KEGG   ENZYME: 1.3.1.62Help
Entry
EC 1.3.1.62                 Enzyme                                 

Name
pimeloyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
pimeloyl-CoA:NAD+ oxidoreductase
Reaction(IUBMB)
pimeloyl-CoA + NAD+ = 6-carboxyhex-2-enoyl-CoA + NADH + H+ [RN:R05311]
Reaction(KEGG)
Substrate
pimeloyl-CoA [CPD:C01063];
NAD+ [CPD:C00003]
Product
6-carboxyhex-2-enoyl-CoA [CPD:C06723];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the benzoate degradation (anaerobic) pathway in bacteria.
History
EC 1.3.1.62 created 2000
Pathway
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04118  pimeloyl-CoA dehydrogenase
Genes
REU: Reut_B4559
REH: H16_B0371(pimC) H16_B0372(pimD) H16_B0383(h16_B0383)
RME: Rmet_5529 Rmet_5530
ADN: Alide_3276
ADK: Alide2_1171
EBA: ebA5669(pimD)
Taxonomy
Reference
1  [PMID:8180704]
  Authors
Gallus C, Schink B.
  Title
Anaerobic degradation of pimelate by newly isolated denitrifying bacteria.
  Journal
Microbiology 140 ( Pt 2):409-16 (1994)
DOI:10.1099/13500872-140-2-409
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.62
IUBMB Enzyme Nomenclature: 1.3.1.62
ExPASy - ENZYME nomenclature database: 1.3.1.62
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.62
BRENDA, the Enzyme Database: 1.3.1.62
CAS: 276682-23-6

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