KEGG   ENZYME: 1.3.1.73
Entry
EC 1.3.1.73                 Enzyme                                 
Name
1,2-dihydrovomilenine reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
17-O-acetylnorajmaline:NADP+ oxidoreductase
Reaction(IUBMB)
17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + NADPH + H+ [RN:R05879]
Reaction(KEGG)
R05879
Substrate
17-O-acetylnorajmaline [CPD:C11809];
NADP+ [CPD:C00006]
Product
1,2-dihydrovomilenine [CPD:C11808];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Forms part of the ajmaline biosynthesis pathway.
History
EC 1.3.1.73 created 2002
Pathway
ec00901  Indole alkaloid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K27778  1,2-dihydrovomilenine reductase
Reference
1  [PMID:12391554]
  Authors
Gao S, von Schumann G, Stockigt J.
  Title
A newly-detected reductase from Rauvolfia closes a gap in the biosynthesis of the antiarrhythmic alkaloid ajmaline.
  Journal
Planta Med 68:906-11 (2002)
DOI:10.1055/s-2002-34935
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.73
IUBMB Enzyme Nomenclature: 1.3.1.73
ExPASy - ENZYME nomenclature database: 1.3.1.73
BRENDA, the Enzyme Database: 1.3.1.73

  All links  
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (16)   

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