KEGG ENZYME: 1.3.1.75

ENZYME: 1.3.1.75

Entry

EC 1.3.1.75                 Enzyme

Name

3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH);
DVR (gene name);
bciA (gene name);
[4-vinyl]chlorophyllide a reductase;
4VCR;
chlorophyllide-a:NADP+ oxidoreductase;
divinyl chlorophyllide a 8-vinyl-reductase;
plant-type divinyl chlorophyllide a 8-vinyl-reductase

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

protochlorophyllide-a:NADP+ C-81-oxidoreductase

Reaction(IUBMB)

protochlorophyllide a + NADP+ = 3,8-divinyl protochlorophyllide a + NADPH + H+ [RN:R06896]

Reaction(KEGG)

R06896;
(other) R06272

Substrate

protochlorophyllide a [CPD:C02880];
NADP+ [CPD:C00006]

Product

3,8-divinyl protochlorophyllide a [CPD:C11831];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

The enzyme, found in higher plants, green algae, and some phototrophic bacteria, is involved in the production of monovinyl versions of (bacterio)chlorophyll pigments from their divinyl precursors. It can also act on 3,8-divinyl chlorophyllide a. cf. EC 1.3.7.13, 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin).

History

EC 1.3.1.75 created 2003, modified 2016

Pathway

ec00860

Porphyrin metabolism

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K19073

divinyl chlorophyllide a 8-vinyl-reductase

Genes

ATH:	AT5G18660(PCB2)

ALY:

9307897

CRB:

17883865

CSAT:

104706180 104735928 104770196

EUS:	EUTSA_v10013668mg

BRP:

103845814

BNA:	106371918 106387806

BOE:

106318279

RSZ:

108815128

THJ:

104802726

CPAP:

110814259

CIT:

102611623

CIC:	CICLE_v10005043mg

PVY:

116105570

MINC:

123210385 123221916

TCC:

18603440

GRA:

105777605

GHI:	107895769 107913651

GAB:

108466514

HSYR:

120119369 120201876

DZI:

111298566

EGR:

104415041

GMX:	100780482 100813325

GSJ:	114376217 114386315

PVU:

137832348

VRA:

106776114

VAR:

108341969

VUN:

114188027

VUM:

124828621

CCAJ:

109803641

APRC:

113874649

MTR:

11443863

TPRA:

123898637

CAM:

101497324

PSAT:

127079223

VVO:	131599957 131631529

LJA:

130725982

ADU:

107471190

AIP:

107622854

AHF:	112716444 112783136

LANG:

109329757 109345279

PCIN:

129309206

QSA:	O6P43_003511

FVE:

101295217

AANS:

126791202

RCN:

112195975

PPER:

18792216

PMUM:

103322926

PAVI:

110751584

PDUL:

117632562

MDM:	103416790 103453029

MSYL:

126596013 126608542

PXB:	103937579 103937586 103943616 103958557

ZJU:

107410210

MNT:

21391831

CSAV:

115722333

CSV:	101218189(DVR)

CMO:

103483795

BHJ:

120069854

MCHA:

111009253

CMAX:

111479393

CMOS:

111458024

CPEP:

111791664

RCU:

8262391

MEAN:

126670378

JCU:

105631824

HBR:

110647459

MESC:

110602306

POP:

7481639

PEU:

105117385

PALZ:

118061037

PNZ:

133704080

JRE:

109005949

CILL:

122300457

CAVE:

132185719

QSU:

112031944

QLO:

115950655

TWL:	120012294 120012850

VVI:

100244223

VRI:

117913865

SLY:

101247061

SPEN:

107007940

SOT:

102602338

SSTN:

125874803

SDUL:

129887276

CANN:

107842746

LBB:

132626823

NTA:	107774957 107794507

NSY:

104215321

NTO:

104092779

NAU:

109223504

INI:

109168326

ITR:

116016667

SIND:

105171428

OEU:

111371466

EGT:

105977914

SSPL:

121799775 121808089

SMIL:

130991651

SHIS:

125218367

APAN:

127249148

HAN:

110871637

ECAD:

122578096

LSV:

111917219

CCAV:

112501561

DCR:

108203180

CSIN:

114306084 114312326

RVL:

131321701

AEW:	130764692 130775127

BVG:

104891135

SOE:

110774885

CQI:	110716408 110735310

ATRI:

130828237

MOF:

131150608

NNU:

104585991

MING:

122057191

TSS:	122653775 122658894

PSOM:

113349600 113357464

OSA:	4332843(DVR)

OBR:

102699390

OGL:

127767432

BDI:

100843699

ATS:

109742416

TDC:	119285672 119318606 119325495

TAES:

123085862 123129079 123139971 123146248

TUA:

125530255

LPER:

127332113

LRD:	124698337 124700320

SBI:

8082294

ZMA:

100281890

MFLO:

136528591 136531209 136531548 136543226 136544985

SITA:

101760694

SVS:

117838525

PVIR:

120652360 120687909

PHAI:

112874535

PDA:

103723232

EGU:

105045229

MUS:

135619684

ZOF:	122001944 122006205

DCT:

110106923

PEQ:

110023072

AOF:

109844069

MSIN:

131231665

ACAK:

137956620

NCOL:

116246015 116253899 116253935 116260576 116263581

ATR:

18445232

CJF:

131066942

SMO:	SELMODRAFT_45092 SELMODRAFT_55147

PPP:

112284586

CRE:	CHLRE_01g042800v5

VCN:	VOLCADRAFT_76013

MNG:

MNEG_2465

CSL:	COCSUDRAFT_35797

CVR:	CHLNCDRAFT_56043

APRO:

F751_3586

OLU:	OSTLU_27566

OTA:	OT_ostta15g01850

BPG:	Bathy02g01050

MIS:	MICPUN_62770(DVR)

MPP:	MICPUCDRAFT_40801(DVR)

PTI:	PHATRDRAFT_30690

FCY:	FRACYDRAFT_259321(DVR2) FRACYDRAFT_268496(DVR1)

TPS:	THAPSDRAFT_270316 THAPSDRAFT_37615

AAF:	AURANDRAFT_20831

EHX:	EMIHUDRAFT_426672 EMIHUDRAFT_464355

GTT:	GUITHDRAFT_89883(DVR)

THIP:

N838_27145

SHAI:

LMH63_10035

LIM:	L103DPR2_01017

HYR:	BSY239_1364

RDP:	RD2015_1031

ROI:	N4261_01175

AGC:	BSY240_3267 BSY240_4518

ABAW:

D5400_18425

PDES:

FE840_006765

BRA:

BRADO2496

BBT:

BBta_2842

AOL:

S58_51160

BRO:	BRAD285_4854

BROS:

QUH67_14450

BOY:	LQG66_11890

BOS:	BSY19_1997

MET:

M446_3136

MOR:

MOC_4712

MPHY:

MCBMB27_03576

METX:

A3862_10955

METS:

DK389_23140

MMES:

MMSR116_23895

MTEA:

DK419_14570

BBAR:

RHAL1_02065

SUAM:

BOO69_04815

SUAL:

KDD17_00480

TOM:	BWR18_03010

RMM:	ROSMUCSMR3_01081

ROK:	RAK1035_0027

RID:	RIdsm_04445

ROH:	FIU89_16900(azoB2)

PLCG:

RVY76_02280

MARU:

FIU81_04640

RED:	roselon_00803

RSP:

RSP_3070

RSH:	Rsph17029_3798

RSQ:	Rsph17025_3907

CAZT:

LV780_16135

RBL:	B6K69_04755

PTP:	RCA23_c29790

RSU:

NHU_01747

RHM:	B5V46_08255

RHC:

RGUI_2175

TAW:	EI545_09375

NSM:	JO391_16245

RBG:	BG454_11220

RCP:	RCAP_rcc03260

NGF:	FRF71_11475

NOG:	GKE62_15975

SGLC:

M1K48_04220

SQO:	NMP03_07000

SRAD:

LLW23_04730

SAAP:

E2E30_04750

CIJ:	WG74_05770

SLAA:

EUU25_10420

PALG:

HFP57_01300

PARJ:

J4G78_07580

SAND:

H3309_06380

POQ:	KZX46_04020

PMEA:

KTC28_07395

ALH:	G6N82_04305

ARUE:

QQX03_03990

ELQ:	Ga0102493_111607

ERK:	CD351_15145

ERF:	FIU90_14995

PNS:	A9D12_07260

ERYT:

KDC96_16135

PORL:

BG023_11867

PHZ:	CHX26_05075

POT:	E2E27_06060

PORC:

CBR61_04890

NCB:	C0V82_19910

NFC:	KG111_11930

AWN:	NQV15_12445

MUZ:	H4N58_11600

SYD:	Syncc9605_1613

SYE:	Syncc9902_1374

SYG:

sync_1014

SYNK:

KR100_07640

SYNR:

KR49_03475

SYND:

KR52_08165

SYH:	Syncc8109_1014

SYNW:

SynWH8103_01101(dvr)

SYW:

SYNW0963

AMR:	AM1_2394(nmrA)

ACAM:

HRE53_09605

LEP:	Lepto7376_1324

GPH:	GEMMAAP_00910

GGR:	HKW67_10010

PSPC:

Strain318_002213

CTE:

CT1063

CPC:

Cpar_1021

CLZ:	BIU88_05785

CCH:

Cag_1059

CPB:	Cphamn1_1379

PVI:

Cvib_0527

PLT:

Plut_0471

PPH:

Ppha_1163

PAA:

Paes_1217

PROC:

Ptc2401_01320(azoB)

PROS:

CHL67_05860

PROW:

OO006_06365

PROI:

OO005_05905

» show all

Reference

1 [PMID:16666133]

Authors

Tripathy BC, Rebeiz CA.

Title

Chloroplast Biogenesis 60 : Conversion of Divinyl Protochlorophyllide to Monovinyl Protochlorophyllide in Green(ing) Barley, a Dark Monovinyl/Light Divinyl Plant Species.

Journal

Plant Physiol 87:89-94 (1988)
DOI:10.1104/pp.87.1.89

Reference

2 [PMID:1390630]

Authors

Parham R, Rebeiz CA.

Title

Chloroplast biogenesis: [4-vinyl] chlorophyllide a reductase is a divinyl chlorophyllide a-specific, NADPH-dependent enzyme.

Journal

Biochemistry 31:8460-4 (1992)
DOI:10.1021/bi00151a011

Reference

3 [PMID:8678296]

Authors

Parham R, Rebeiz CA.

Title

Chloroplast biogenesis 72: a [4-vinyl]chlorophyllide a reductase assay using divinyl chlorophyllide a as an exogenous substrate.

Journal

Anal Biochem 231:164-9 (1995)
DOI:10.1006/abio.1995.1516

Reference

4 [PMID:11488624]

Authors

Kolossov VL, Rebeiz CA.

Title

Chloroplast biogenesis 84: solubilization and partial purification of membrane-bound [4-vinyl]chlorophyllide a reductase from etiolated barley leaves.

Journal

Anal Biochem 295:214-9 (2001)
DOI:10.1006/abio.2001.5195

Reference

5 [PMID:15632054]

Authors

Nagata N, Tanaka R, Satoh S, Tanaka A

Title

Identification of a vinyl reductase gene for chlorophyll synthesis in Arabidopsis thaliana and implications for the evolution of Prochlorococcus species.

Journal

Plant Cell 17:233-40 (2005)
DOI:10.1105/tpc.104.027276

Sequence

[ath:AT5G18660]

Reference

6 [PMID:17148453]

Authors

Chew AG, Bryant DA

Title

Characterization of a plant-like protochlorophyllide a divinyl reductase in green sulfur bacteria.

Journal

J Biol Chem 282:2967-75 (2007)
DOI:10.1074/jbc.M609730200