KEGG ENZYME: 1.3.5.6

ENZYME: 1.3.5.6

Entry

EC 1.3.5.6                  Enzyme

Name

9,9'-dicis-zeta-carotene desaturase;
zeta-carotene desaturase;
ZDS

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With a quinone or related compound as acceptor

Sysname

9,9'-dicis-zeta-corotene:quinone oxidoreductase

Reaction(IUBMB)

9,9'-dicis-zeta-carotene + 2 quinone = 7,9,7',9'-tetracis-lycopene + 2 quinol (overall reaction) [RN:R07511];
(1a) 9,9'-dicis-zeta-carotene + a quinone = 7,9,9'-tricis-neurosporene + a quinol [RN:R09656];
(1b) 7,9,9'-tricis-neurosporene + a quinone = 7,9,7',9'-tetracis-lycopene + a quinol [RN:R09658]

Reaction(KEGG)

R07511 R09656 R09658;
(other) R04798 R04800

Substrate

9,9'-dicis-zeta-carotene [CPD:C15857];
quinone [CPD:C15602];
7,9,9'-tricis-neurosporene [CPD:C19759]

Product

7,9,7',9'-tetracis-lycopene [CPD:C15858];
quinol [CPD:C15603];
7,9,9'-tricis-neurosporene [CPD:C19759]

Comment

This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria.

History

EC 1.3.5.6 created 1999 as EC 1.14.99.30, transferred 2011 to EC 1.3.5.6

Pathway

ec00906

Carotenoid biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K00514

zeta-carotene desaturase

Genes

ATH:	AT3G04870(ZDS)

ALY:

9320542

CRB:

17893635

CSAT:

104705395 104744597 104764122

EUS:	EUTSA_v10020402mg

BRP:

103849152

BNA:	106427407 106453079

BOE:

106295419

RSZ:

108863436

THJ:

104821685

CPAP:

110809670

CIT:	102577969(CitZDS)

PVY:

116133864

MINC:

123221170

TCC:

18600240

GRA:	105782169 105804712

GHI:	107888796 107893220 107920020 107945977

GAB:	108461129 108472101

HSYR:

120138884 120161778

DZI:	111277201 111296669

EGR:

104430315

RARG:

115743937

GMX:	100776502 100816122

GSJ:	114371240 114403049

PVU:

137829901

VRA:

106772487

VAR:

108345914

VUN:

114191961

VUM:

124828385

CCAJ:

109789910

APRC:

113871335

MTR:

11415648

TPRA:

123903098

CAM:

101493508

PSAT:

127098549

VVO:	131627424 131644135

LJA:

130718205

ADU:

107465815

AIP:

107617599

AHF:	112710918 112776436

LANG:

109336428 109345421 109354942

PCIN:

129306399

QSA:	O6P43_007610

FVE:

101296114

AANS:

126798042

RCN:

112192306

PPER:

18772557

PMUM:

103318575

PAVI:

110755575 110759721

PDUL:

117632924

MDM:	103434148 103451012

MSYL:

126593685 126619154

PXB:

103954429

PCOX:

137722295 137744714

ZJU:

107412247

MNT:

21389609

CSAV:

115721277 133034877

HLP:

133790777

CSV:

101210522

CMO:

103501020

BHJ:

120071290

MCHA:

111025098

CMAX:

111495951

CMOS:

111440894

CPEP:

111792647

RCU:

8289444

MEAN:

126673260

JCU:

105647663

HBR:	110656752 110662590

MESC:

110620945

POP:	18098943 7473341

PEU:	105111905 105131258

PALZ:

118044066 118051360 118056983 118061421

PNZ:	133670153 133695342

JRE:

109009708

CILL:

122316751

CAVE:

132171613

AGLU:

133851679

QSU:

111983961

QLO:	115980038 115981676

CSAA:

142628326

TWL:

120009935

VVI:

100245154

VRI:

117930372

SLY:	543629(zds)

SPEN:

107003189

SOT:

102598493

SSTN:

125853351

SDUL:

129886298

SVER:

125815208

CANN:

107839468 107839472

LBB:

132645253

NTA:	107772271 107830915

NSY:

104239912

NTO:

104085990

NAU:

109237858

INI:

109182207

ITR:

116007099

SIND:

105162430 105172259

OEU:	111379201 111379204

EGT:	105964808 105974162 105974562

SSPL:

121765143 121793432 121797720 121799747

SMIL:

130998871 130998879

SHIS:

125203525 125223442

APAN:

127245726 127260962

HPUM:

140879709

PHUA:

140960412 140986301

PEBU:

140841404

PTAB:

142530884

CARB:

113727469 113732666

HAN:

110909342

BHW:	143537561 143577914

ECAD:

122603044

LSV:

111883354

CCAV:

112509585

DCR:	108196705 108209330

AGRV:

141661778 141668909

CSIN:

114319340

RVL:

131332370

AEW:	130783708 130795367

DLT:

127801158

CFLO:

132299857

BVG:

104890922

SOE:

110797887

CQI:	110708463 110737059

ATRI:

130817454

SLAF:

141657486

MOF:

131154598

NNU:

104596524

MING:

122091296

TSS:

122668779

PSOM:

113332730 113347119

OSA:

4342680

DOSA:

Os07g0204900

OBR:

102721567

OGL:

127780101

BDI:

100836583

ATS:

109753119

TDC:	119354461 119363591

TAES:

100270658 123044758 123052650

TUA:

125537055

HVG:

123425989

LPER:

127321959

LRD:

124674719

SBI:

8078415

ZMA:

542604

MFLO:

136541581 136545392

SITA:

101786776

SVS:

117843813

PVIR:

120659662 120665630

PHAI:

112879845

PAUA:

133890650 133892664

TANG:

140759615

CROT:

144575408(ZDS)

PDA:

103723760

EGU:

105054948

MUS:

135610174

ZOF:	121971957 121976980

DCT:

110095455

PEQ:

110023507

AOF:

109833809

ACAK:

137945227

NCOL:

116255365

ATR:

18448792

CJF:

131036090

SMO:	SELMODRAFT_108745 SELMODRAFT_146971

PPP:	112277797 112292818 112294714

CRE:	CHLRE_07g314150v5

VCN:	VOLCADRAFT_95071

MNG:	MNEG_10716

CSL:	COCSUDRAFT_35471

CVR:	CHLNCDRAFT_141585(ZDS)

APRO:

F751_3908

CME:	CYME_CMT061C

GSL:	Gasu_31940

CCP:	CHC_T00008407001

PTI:	PHATRDRAFT_53974(ZDS)

FCY:	FRACYDRAFT_291551(ZDS)

TPS:	THAPSDRAFT_24832

AAF:	AURANDRAFT_71930

EHX:	EMIHUDRAFT_421941

GTT:	GUITHDRAFT_93434

PALJ:

LZC94_27750

CTE:

CT1414

CPC:

Cpar_0751

CLZ:	BIU88_03670

CCH:

Cag_1590

CPH:	Cpha266_0830

CPB:	Cphamn1_0949

CLI:

Clim_0916

PVI:

Cvib_1233

PLT:

Plut_1415

PPH:

Ppha_1769

PAA:

Paes_1524

PROC:

Ptc2401_00675(pds_1)

PRS:	B9H02_04065

PROS:

CHL67_03655

PROW:

OO006_08930

PROI:

OO005_08230

CTS:

Ctha_1697

PNK:	AASFL403_19565

SYN:	slr0940(crtQ)

SYZ:	MYO_118430(crtQ)

SYY:	SYNGTS_1826(crtQ)

SYT:	SYNGTI_1826(crtQ)

SYS:	SYNPCCN_1825(crtQ)

SYQ:	SYNPCCP_1825(crtQ)

SYJ:	D082_20520(crtQ-2)

SYO:	C7I86_09510(zds)

SYNH:

HTZ78_03750(zds)

SYNS:

OLK001_09940

SYC:	syc2497_c(zds)

SYU:	M744_08565

SYF:	Synpcc7942_1512

SYD:	Syncc9605_2356

SYE:	Syncc9902_0335

SYG:

sync_2568

SYR:	SynRCC307_0275(crtQ)

SYX:	SynWH7803_2224(crtQ)

CYA:	CYA_0668(zds)

CYB:	CYB_1060(zds)

SYNE:

Syn6312_1408

SYNP:

Syn7502_03575

SYNK:

KR100_14605

SYNR:

KR49_07360

SYND:

KR52_04330

SYH:	Syncc8109_2460(crtQ)

SYNW:

SynWH8103_02544(zds)

SYNC:

CB0101_10980(zds)

SYNY:

BM449_04240

SYNZ:

H8F24_02355(zds)

SYNL:

KJJ24_09080(zds)

SYNO:

LY254_10035(zds)

SYNU:

SynWH8101_2566

SYW:	SYNW2213(crtQ)

CGC:	Cyagr_2942

CYI:	CBM981_3121(zds)

PMA:	Pro_0136(crtQ)

PMM:	PMM0115(crtQ)

PMT:

PMT_1968

PMN:	PMN2A_1484

PMI:	PMT9312_0118

PMB:	A9601_01331(crtQ)

PMC:	P9515_01291(crtQ)

PMF:	P9303_26211(crtQ)

PMG:	P9301_01321(crtQ)

PMH:	P9215_01331(crtQ)

PMJ:	P9211_01311(crtQ)

PME:	NATL1_01891(crtQ)

PRC:

EW14_0141

PRM:

EW15_0204

WNA:	KA717_20885(zds)

CMP:	Cha6605_0709

CYN:	Cyan7425_3176

CEP:	Cri9333_4053

TVN:	NIES2134_100610(crtQ)

SLW:	BRW62_02590

TEL:	tll0337(crtQ)

THN:	NK55_00380(crtQ)

THEC:

FFX45_00400(zds)

THEY:

JW907_00395(zds)

TSQ:	D3A95_05655(zds)

AMR:

AM1_3692

ACAM:

HRE53_15085(zds)

TSZ:	OOK60_17185(zds)

LEN:	LEP3755_42080

LET:	O77CONTIG1_02617(pds_2)

LBO:	LBWT_35440

LEPI:

EDM05_66145(zds)

KOV:	K9N68_24890(zds)

LSC:	KIK02_22960(zds)

LSK:	J5X98_09255(zds)

SFRI:

RBJ76_08710(zds)

HHG:	XM38_043900

DSL:	Dacsa_1294

PSEU:

Pse7367_2939

PSER:

ABRG53_3074(crtQ)

PGX:	OA858_03700(zds)

THEU:

HPC62_02610(zds)

TOG:	HNI00_05410(zds)

TSIN:

OXH18_09360(zds)

CHON:

NIES4102_31770

GDU:	P0S91_12035(zds)

GEN:	GM3709_2071

GEE:	GM3708_3458

CAN:	Cyan10605_2265

CSN:	Cyast_1610

CYL:	AA637_06790(crtQ)

CYR:	A5482_005065(zds)

CYD:	Dongsha4_03245(zds)

SYP:	SYNPCC7002_A0529(crtQ)

SYV:	AWQ23_02815

SYL:	AWQ21_02615

LEP:	Lepto7376_0182

SYNN:

NIES970_10330(crtQ)

PIP:	FEK30_06745(zds)

MAR:	MAE_53100(crtQ)

MPK:

VL20_1522

MIQ:	B5D77_20965

MVZ:	myaer102_25870(crtQ)

MIBL:

ACE3JL_15280(zds)

MICD:

ACQY1Y_23605(zds)

MPRC:

ACQY1X_23700(zds)

HAO:	PCC7418_2975

ENN:	FRE64_00510(zds)

CYT:	cce_2779(crtQ)

CWA:	CwatDRAFT_5404

CYP:	PCC8801_3430

CYH:	Cyan8802_2686

CYC:	PCC7424_0679

TER:

Tery_3954

PAGH:

NIES204_05360(crtQb)

PPSU:

NO713_02569(crtQ)

PRUN:

PCC7821_03755(crtQ)

MVAG:

D0A34_16550(zds)

LFS:	HFV01_07070(zds)

LIX:	H2674_18710(zds)

ARP:	NIES39_B00980(crtQb)

CSAU:

ACL6C3_26720(zds)

OXY:	HCG48_04035(zds)

OAC:	Oscil6304_0259

PHOR:

JWS08_13970(zds)

PYH:	NEA10_18420(zds)

ONI:	Osc7112_1468

MIC:	Mic7113_1472

MPRO:

BJP34_05885

GEI:	GEI7407_2276

ANA:	all2382(crtQ)

NPU:	Npun_R0498

NOS:	Nos7107_5121

NOP:	Nos7524_4587

NON:	NOS3756_07760(crtQ)

NFL:	COO91_05714

NOE:	CLI64_24205(zds)

NSH:

GXM_02002

NED:	HUN01_23865(zds)

NLK:	NIES25_05320

NCW:	NIES2107_45990

NCF:	ANSO36C_24710(crtQ)

NOST:

GJB62_02895(zds)

NOSU:

JYQ62_05250(zds)

NOSQ:

PQG02_08915(zds)

NOSZ:

WKK05_21085(zds)

NOSC:

L6494_23020(zds)

AVA:

Ava_0200

NAZ:

Aazo_4788

ANB:	ANA_C11939

ACY:	Anacy_2337

AWA:	AA650_01540

ANN:	EH233_15050(zds)

CSG:	Cylst_6049

RSIN:

B6N60_02861

HBQ:	QI031_05555(zds)

NSP:	BMF81_00045(crtQ)

NSPH:

BDGGKGIB_04406(pds_4)

AEE:	IM676_12935(zds)

CALO:

Cal7507_4291

CALT:

Cal6303_5059

CALH:

IJ00_20820

CALN:

NIES2098_35990

RIV:	Riv7116_6892

MDP:	NIES3275_50190

FIS:	FIS3754_41450

DOU:	BMF77_00518(pds_1)

DFS:	HGD76_13440(zds)

DHT:	NG743_15530(zds)

DCM:	NIES806_24910

DOT:	EZY12_08600(zds)

DOZ:	HEP80_15540(zds)

DOC:	HEQ26_01885(zds)

CCUR:

IAR63_16840(zds)

CRK:	L3I90_09045(zds)

AFLO:

HEQ12_11555(zds)

STOQ:

K2F26_19300(zds)

SKV:	NIES73_12930

RCS:	NIES932_20800

OCF:	WJM97_09120(zds)

TOQ:	HCG51_23730(zds)

TTQ:	NIES37_07970

TOI:	HG267_16970(zds)

TOZ:	HGR01_01840(zds)

ALAX:

NIES50_11860

SCYT:

SAMD_16570

SCYS:

NIES4073_05500

BSEN:

DP114_10240(zds)

BOX:	DP113_10185(zds)

NCN:	BZZ01_28110

CTHE:

Chro_1619

PLP:	Ple7327_2403

SCS:	Sta7437_0865

STAN:

STA3757_45750

GLT:	GlitD10_0032(crtQ)

GCY:	LQF76_09275(zds)

DTB:	BH720_029215(zds)

CEO:	ETSB_0758(crtQ)

CER:	RGRSB_0718(crtQ)

CEEC:

P3F56_03720(zds)

» show all

Reference

1 [PMID:8617254]

Authors

Albrecht M, Linden H, Sandmann G.

Title

Biochemical characterization of purified zeta-carotene desaturase from Anabaena PCC 7120 after expression in Escherichia coli.

Journal

Eur J Biochem 236:115-20 (1996)
DOI:10.1111/j.1432-1033.1996.00115.x

Reference

2 [PMID:10938359]

Authors

Josse EM, Simkin AJ, Gaffe J, Laboure AM, Kuntz M, Carol P

Title

A plastid terminal oxidase associated with carotenoid desaturation during chromoplast differentiation.

Journal

Plant Physiol 123:1427-36 (2000)
DOI:10.1104/pp.123.4.1427

Reference

3 [PMID:10491195]

Authors

Breitenbach J, Kuntz M, Takaichi S, Sandmann G

Title

Catalytic properties of an expressed and purified higher plant type zeta-carotene desaturase from Capsicum annuum.

Journal

Eur J Biochem 265:376-83 (1999)
DOI:10.1046/j.1432-1327.1999.00746.x

Sequence

[ag:CAA61985]

Reference

4 [PMID:15503129]

Authors

Breitenbach J, Sandmann G

Title

zeta-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene.

Journal

Planta 220:785-93 (2005)
DOI:10.1007/s00425-004-1395-2

Sequence

[ag:CAA61985]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.5.6

IUBMB Enzyme Nomenclature:

1.3.5.6

ExPASy - ENZYME nomenclature database:

1.3.5.6

BRENDA, the Enzyme Database:

1.3.5.6

All links

Gene (5402)   
   MGENES (2119)   
   RefGene (3283)   
Protein sequence (2381)   
   UniProt (1211)   
   SWISS-PROT (10)   
   RefSeq(pep) (1160)   
DNA sequence (2599)   
   RefSeq(nuc) (1863)   
   GenBank (436)   
   EMBL (300)   
Protein domain (1)   
   InterPro (1)   
All databases (10383)   

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