KEGG   ENZYME: 1.3.7.13
Entry
EC 1.3.7.13                 Enzyme                                 

Name
3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin);
bciB (gene name);
cyano-type divinyl chlorophyllide a 8-vinyl-reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With an iron-sulfur protein as acceptor
Sysname
protochlorophyllide-a:ferredoxin C-81-oxidoreductase
Reaction(IUBMB)
protochlorophyllide a + 2 oxidized ferredoxin [iron-sulfur] cluster = 3,8-divinyl protochlorophyllide a + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ [RN:R11519]
Reaction(KEGG)
R11519
Substrate
protochlorophyllide a [CPD:C02880];
oxidized ferredoxin [iron-sulfur] cluster [CPD:C00139]
Product
3,8-divinyl protochlorophyllide a [CPD:C11831];
reduced ferredoxin [iron-sulfur] cluster [CPD:C00138];
H+ [CPD:C00080]
Comment
The enzyme, found in many phototrophic bacteria, land plants, and some green and red algae, is involved in the production of monovinyl versions of (bacterio)chlorophyll pigments from their divinyl precursors. Binds two [4Fe-4S] clusters and an FAD cofactor. It can also act on 3,8-divinyl chlorophyllide a, 3,8-divinyl chlorophyll a, and chlorophyll c2. cf. EC 1.3.1.75, 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH).
History
EC 1.3.7.13 created 2016
Pathway
ec00860  Porphyrin and chlorophyll metabolism
ec01100  Metabolic pathways
Orthology
K21231  3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin)
Genes
ALV: Alvin_1181
TVI: Thivi_1847
MPUR: MARPU_13415
TSY: THSYN_32255
TTP: E6P07_07490
SYN: slr1923
SYZ: MYO_120210
SYY: SYNGTS_2003(slr1923)
SYT: SYNGTI_2002(slr1923)
SYS: SYNPCCN_2001(slr1923)
SYQ: SYNPCCP_2001(slr1923)
SYC: syc0195_d
SYR: SynRCC307_0774(frhB)
SYX: SynWH7803_1550(frhB)
SYP: SYNPCC7002_A2638(fruB)
CYA: CYA_1215
CYB: CYB_1261
TEL: tll1845
THN: NK55_05905(cvrA)
AMR: AM1_2849(frhB)
MAR: MAE_40060
CYL: AA637_09240(frhB)
CYT: cce_4662
TER: Tery_0742
GLJ: GKIL_2429(frhB) GKIL_4087(frhB)
ANA: all1601
NSH: GXM_03620
AVA: Ava_4214
NAZ: Aazo_3552
CALH: IJ00_05065
CTHE: Chro_1099
CAU: Caur_2555
CAG: Cagg_3479
PPH: Ppha_2739
PAA: Paes_0603
CTS: Ctha_1208
 » show all
Reference
1  [PMID:17148453]
  Authors
Chew AG, Bryant DA
  Title
Characterization of a plant-like protochlorophyllide a divinyl reductase in green sulfur bacteria.
  Journal
J Biol Chem 282:2967-75 (2007)
DOI:10.1074/jbc.M609730200
Reference
2  [PMID:24151992]
  Authors
Saunders AH, Golbeck JH, Bryant DA
  Title
Characterization of BciB: a ferredoxin-dependent 8-vinyl-protochlorophyllide reductase from the green sulfur bacterium Chloroherpeton thalassium.
  Journal
Biochemistry 52:8442-51 (2013)
DOI:10.1021/bi401172b
  Sequence
[cts:Ctha_1208]
Reference
3  [PMID:24399236]
  Authors
Ito H, Tanaka A
  Title
Evolution of a new chlorophyll metabolic pathway driven by the dynamic changes in enzyme promiscuous activity.
  Journal
Plant Cell Physiol 55:593-603 (2014)
DOI:10.1093/pcp/pct203
  Sequence
[syn:slr1923]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.7.13
IUBMB Enzyme Nomenclature: 1.3.7.13
ExPASy - ENZYME nomenclature database: 1.3.7.13
BRENDA, the Enzyme Database: 1.3.7.13

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