KEGG   ENZYME: 1.3.8.5
Entry
EC 1.3.8.5                  Enzyme                                 
Name
short-chain 2-methylacyl-CoA dehydrogenase;
ACADSB (gene name);
2-methylacyl-CoA dehydrogenase;
branched-chain acyl-CoA dehydrogenase (ambiguous);
2-methyl branched chain acyl-CoA dehydrogenase;
2-methylbutanoyl-CoA:(acceptor) oxidoreductase;
2-methyl-branched-chain-acyl-CoA:electron-transfer flavoprotein 2-oxidoreductase;
2-methyl-branched-chain-enoyl-CoA reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With a flavin as acceptor
Sysname
short-chain 2-methylacyl-CoA:electron-transfer flavoprotein 2-oxidoreductase
Reaction(IUBMB)
2-methylbutanoyl-CoA + electron-transfer flavoprotein = (E)-2-methylbut-2-enoyl-CoA + reduced electron-transfer flavoprotein + H+ [RN:R03169]
Reaction(KEGG)
R03169;
(other) R02661 R03172 R04751
Substrate
2-methylbutanoyl-CoA [CPD:C01033];
electron-transfer flavoprotein [CPD:C04253]
Product
(E)-2-methylbut-2-enoyl-CoA [CPD:C03345];
reduced electron-transfer flavoprotein [CPD:C04570];
H+ [CPD:C00080]
Comment
A flavoprotein (FAD). The mammalian enzyme catalyses an oxidative reaction as a step in the mitochondrial beta-oxidation of short-chain 2-methyl fatty acids and participates in isoleucine degradation. The enzyme from the parasitic helminth Ascaris suum catalyses a reductive reaction as part of a fermentation pathway, shuttling reducing power from the electron-transport chain to 2-methyl branched-chain enoyl CoA.
History
EC 1.3.8.5 created 1992 as EC 1.3.1.52, transferred 2012 to EC 1.3.8.5 (EC 1.3.99.12, created 1986, incorporated 2020), modified 2020
Pathway
ec00071  Fatty acid degradation
ec00280  Valine, leucine and isoleucine degradation
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09478  short-chain 2-methylacyl-CoA dehydrogenase
K11410  short-chain 2-methylacyl-CoA dehydrogenase
Genes
HSA36(ACADSB)
PTR745464(ACADSB)
PPS100991276(ACADSB)
GGO101132470(ACADSB)
PON100171571(ACADSB)
NLE100603582(ACADSB)
MCC707487(ACADSB)
MCF102133754(ACADSB)
CSAB103216651(ACADSB)
CATY105578003(ACADSB)
PANU101010148(ACADSB)
TGE112631223(ACADSB)
RRO104658093(ACADSB)
RBB108519576(ACADSB)
TFN117065359(ACADSB)
PTEH111550816(ACADSB)
CJC100396089(ACADSB)
SBQ101028121(ACADSB)
CSYR103273161(ACADSB)
MMUR105880343(ACADSB)
OGA100953370(ACADSB)
MMU66885(Acadsb)
MCAL110299023(Acadsb)
MPAH110326470(Acadsb)
RNO25618(Acadsb)
MCOC116103099(Acadsb)
MUN110564692
CGE100766828(Acadsb)
PLEU114692584(Acadsb)
NGI103729261(Acadsb)
HGL101698912(Acadsb)
CPOC100714817(Acadsb)
CCAN109691642(Acadsb)
DORD105989765(Acadsb)
DSP122126854(Acadsb)
OCU100351868(ACADSB)
OPI101520488(ACADSB)
TUP102474463(ACADSB)
CFA477856(ACADSB)
VVP112928830(ACADSB)
VLG121484200(ACADSB)
AML100470228(ACADSB)
UMR103657958(ACADSB)
UAH113252021(ACADSB)
UAR123803910(ACADSB)
ELK111145042
LLV125084472
MPUF101674215(ACADSB)
ORO101373794(ACADSB)
EJU114221858(ACADSB)
ZCA113918458(ACADSB)
MLX118027358(ACADSB)
FCA101092794(ACADSB)
PYU121037337(ACADSB)
PBG122493340(ACADSB)
PTG102951023(ACADSB)
PPAD109252314(ACADSB)
AJU106969392(ACADSB)
HHV120235521(ACADSB)
BTA504301(ACADSB)
BOM102266366(ACADSB)
BIU109579124(ACADSB)
BBUB102397738(ACADSB)
CHX102177588(ACADSB)
OAS101102606(ACADSB)
ODA120873887(ACADSB)
CCAD122445842(ACADSB)
SSC100154810(ACADSB)
CFR102517479(ACADSB)
CBAI105067638(ACADSB)
CDK105085769(ACADSB)
VPC102530289(ACADSB)
BACU102999342(ACADSB)
LVE103077062(ACADSB)
OOR101289781(ACADSB)
DLE111172226(ACADSB)
PCAD102992141(ACADSB)
PSIU116741947(ACADSB)
ECB100057998(ACADSB)
EPZ103543854 103557817
EAI106847757(ACADSB)
MYB102253452(ACADSB)
MYD102769159(ACADSB)
MMYO118669618(ACADSB)
MLF102426270(ACADSB)
MNA107532676(ACADSB)
PKL118719613(ACADSB)
HAI109396916(ACADSB)
DRO112300262(ACADSB)
SHON118990529(ACADSB)
AJM119059542(ACADSB)
PDIC114497198(ACADSB)
PHAS123828694(ACADSB)
MMF118632767(ACADSB)
RFQ117018663 117036024(ACADSB)
PALE102891849(ACADSB)
PVP105295679(ACADSB)
MJV108390573(ACADSB)
TOD119234148(ACADSB)
SARA101540063(ACADSB)
LAV100658432(ACADSB)
TMU101353141
DNM101442022(ACADSB)
MDO100025277(ACADSB)
GAS123238205(ACADSB)
SHR100925751(ACADSB)
PCW110192795(ACADSB)
OAA100086999(ACADSB)
GGA423947(ACADSB)
PCOC116231551(ACADSB)
MGP100542282(ACADSB)
CJO107316256(ACADSB)
NMEL110399180(ACADSB)
APLA101793844(ACADSB)
ACYG106038988(ACADSB)
AFUL116491073(ACADSB)
TGU100217590(ACADSB)
LSR110468433(ACADSB)
SCAN103813777(ACADSB)
PMOA120500006(ACADSB)
OTC121341683(ACADSB)
PRUF121350144(ACADSB)
GFR102040450(ACADSB)
FAB101819094(ACADSB)
PHI102100927(ACADSB)
PMAJ107206820(ACADSB)
CCAE111931386(ACADSB)
CCW104694570(ACADSB)
ETL114070836(ACADSB)
ZAB102061915(ACADSB)
FPG101917969(ACADSB)
FCH102057808(ACADSB)
CLV102096980(ACADSB)
EGZ104128327(ACADSB)
NNI104022112(ACADSB)
ACUN113481576(ACADSB)
TALA104363380(ACADSB)
PADL103918535(ACADSB)
ACHC115348115(ACADSB)
AAM106494200(ACADSB)
AROW112966013(ACADSB)
NPD112947790(ACADSB)
DNE112994034(ACADSB)
ASN102386096(ACADSB)
AMJ102577069(ACADSB)
CPOO109324120(ACADSB)
GGN109287690(ACADSB)
PSS102458654(ACADSB)
CMY102942130(ACADSB)
CPIC101938408(ACADSB)
TST117881058(ACADSB)
CABI116834432(ACADSB)
MRV120409153(ACADSB)
ACS100556766(acadsb)
PVT110087224(ACADSB)
SUND121926642(ACADSB)
PBI103066261(ACADSB)
PMUR107285940(ACADSB)
TSR106554066(ACADSB)
PGUT117676700(ACADSB)
VKO123031110(ACADSB)
PMUA114597407(ACADSB)
ZVI118096516(ACADSB)
GJA107116296(ACADSB)
XLA494679(acadsb.L)
XTR448259(acadsb)
NPR108784780(ACADSB)
RTEM120946704(ACADSB)
BBUF121003427(ACADSB)
BGAR122939774(ACADSB)
DRE100037342(acadsb) 110437777(acadsb)
SRX107746745
SANH107684586
SGH107574492 107580754
CAUA113055802 113055901
IPU108273611(acadsb)
PHYP113527247(acadsb)
SMEO124388480(acadsb)
AMEX103042655(acadsb)
EEE113588401(acadsb)
TRU101075946(acadsb)
TNGGSTEN00012530G001
LCO104926628(acadsb)
NCC104954036(acadsb)
CGOB115024463(acadsb)
ELY117246729(acadsb)
PLEP121959173(acadsb)
SLUC116061434(acadsb)
ECRA117937079(acadsb)
PFLV114548099(acadsb)
GAT120819195(acadsb)
PPUG119213264(acadsb)
MSAM119915473(acadsb)
CUD121528185(acadsb)
MZE101471898(acadsb)
ONL100692418(acadsb)
OAU116328816(acadsb)
OLA101163855(acadsb)
OML112154111(acadsb)
XMA102220838(acadsb)
XCO114152310(acadsb)
XHE116727535(acadsb)
PRET103481581(acadsb)
PFOR103150604(acadsb)
PLAI106951746(acadsb)
PMEI106922409(acadsb)
GAF122823478(acadsb)
CVG107090227(acadsb)
CTUL119775960(acadsb)
GMU124874815(acadsb)
NFU107387801(acadsb)
KMR108246997(acadsb)
ALIM106516587(acadsb)
NWH119423721(acadsb)
AOCE111582229(acadsb)
CSEM103381955(acadsb)
POV109626616(acadsb)
SSEN122759127(acadsb)
HHIP117753123(acadsb)
LCF108899015(acadsb)
SDU111220345(acadsb)
SLAL111660219(acadsb)
XGL120794321(acadsb)
HCQ109523983(acadsb)
BPEC110165473(acadsb)
MALB109962961(acadsb)
SASA106575476 106577431
OTW112236388(acadsb)
OMY110511537 110531877 118966130
OGO124018349 124018350 124018361
SALP112075854
SNH120036957 120038512
ELS105009552(acadsb)
SFM108939566(acadsb)
PKI111853681(acadsb)
AANG118217576(acadsb)
LOC102695849(acadsb)
PSPA121322435 121325972
ARUT117418434(acadsb)
LCM102365761(ACADSB)
CMK103185437(acadsb)
RTP109927465(acadsb)
BFO118414863
BBEL109471473
SPU593139
APLC110988182
SKO100378591
DMEDmel_CG3902(CG3902)
DER6545091
DSE6618359
DSIDsimw501_GD12323(Dsim_GD12323)
DYADyak_GE22545 Dyak_GE22549
DAN6493668
DSR110185241
DPODpse_GA17761
DPE6595810
DMN108153425
DWI6645938
DGR6557827
DMODmoj_GI11829
DNV108650232
DHE111592256
DVI6624036
CCAT101448771
BOD106621980
MDE101890297
SCAC106084745
LCQ111690724
AGAAgaP_AGAP009783
ACOZ120957175
AARA120902866
AAG5569333
AALB109407248 115258624
CQUCpipJ_CPIJ009148
CPII120428341
CNS116344277
AME409712
ACER108000837
ALAB122713002
BIM100749552
BBIF117208917
BVK117230754
BVAN117166325
BTER100649947
BPYO122575479
CCAL108628770
OBB114880543
MGEN117218232
NMEA116431539
CGIG122394773
SOC105198238 105200366
MPHA105829763 105836416
AEC105143927
ACEP105618707 105620526
PBAR105428815
VEM105565887 105566772
HST105185846 109504503
DQU106744734 106751200
CFO105250026
FEX115239064
LHU105674413
PGC109859061
OBO105285330 105286634
PCF106790286
PFUC122515375
VPS122636144
NVI100120366 103315463
CSOL105365671
TPRE106657840
MDL103579394
CGLO123265115
FAS105271986
DAM107040820
AGIF122848924
CCIN107266330
TCA657543 660569
DPA109540223
SOY115888800
ATD109595381
CSET123323030
AGB108916585
LDC111506372
NVL108567387 108567469
APLN108739121
PPYR116163432 116163438
OTU111413217 111413219 111423491
BMOR733139(Acade)
MSEX115442043 119189779
DPLKGM_211032B
BANY112051716
PMAC106716140
PPOT106104020
PXU106116729
PRAP111002788
ZCE119833809
HAW110372345
TNL113505313
OFU114359408
PXY105383530
API100161123
DNX107163553
AGS114124068
RMD113551881
BTAB109039976
DCI103511898
CLEC106664106
HHAL106682813
NLU111045258 120351105 120351214 120351215
PHUPhum_PHUM226870 Phum_PHUM226980
FOC113213120 113214143
ZNE110839588
CSEC111874809
FCD110852222
DPXDAPPUDRAFT_216649
DMK116927994
PVM113821404
PJA122257914
HAME121864223
PCLA123745291
PTRU123519321
HAZT108664568
TUT107368035 107368037 107368406
DPTE113793263
DFR124492942
CSCU111633258
CELCELE_C55B7.4(acdh-1) CELE_K06A5.6(acdh-3) CELE_T10E9.9(acdh-4)
CBRCBG_12633 CBG_12644(Cbr-acdh-1) CBG_12664
NAINECAME_06715
TSPTsp_04649
LGILOTGIDRAFT_235352
PCAN112563554
BGT106074053
GAE121384123
HRF124138069
HRJ124274560
CRG105329007
MYI110442658
PMAX117320595 117339390
MMER123546362
OBI106881672
OSN115219213
LAK106173907
OVIT265_13702
NVE5508334
EPA110246509
ATEN116293762
AMIL114958115
PDAM113681854
SPIS111331973
DGT114515827
XEN124443586
HMG100205931
TADTRIADDRAFT_19851 TRIADDRAFT_20131 TRIADDRAFT_33900 TRIADDRAFT_58518
AQU100640316
QSU112003075
CMECYME_CML080C
GSLGasu_17150 Gasu_59510
SLBAWJ20_448
NCRNCU06543
NTENEUTE1DRAFT145014(NEUTE1DRAFT_145014)
SMPSMAC_04665
PANPODANS72p032
TTTTHITE_2114314
MTMMYCTH_2310435
CTHRCTHT_0037110
TMNUCRPA7_8128
SSCKSPSK_09149
FGRFGSG_09661
FPUFPSE_05941
FVRFVEG_06269
FOXFOXG_08409
TRETRIREDRAFT_75175
TRRM419DRAFT_96652
CMTCCM_00006
PLJVFPFJ_06541
VALVDBG_03478
VDAVDAG_09908
CFJCFIO01_11312
SAPOSAPIO_CDS7574
ELAUCREL1_10586
PFYPFICI_04716
BFUBCIN_12g04690
MBEMBM_00834
PSCOLY89DRAFT_685177
GLZGLAREA_09258
AALTCC77DRAFT_1053649
ZTRMYCGRDRAFT_104112
PFJMYCFIDRAFT_58199
BCOMBAUCODRAFT_31007
TMLGSTUM_00006562001
TMSTREMEDRAFT_64236
TASAA1Q1_02301
TVSTRAVEDRAFT_144721
DSQDICSQDRAFT_135367
PCOPHACADRAFT_249214
SHSSTEHIDRAFT_158089
HIRHETIRDRAFT_314566
PSQPUNSTDRAFT_132268
ADLAURDEDRAFT_143192
FMEFOMMEDRAFT_135127
GTRGLOTRDRAFT_126037
MRRMoror_10865
ABPAGABI1DRAFT116215(AGABI1DRAFT_116215)
ABVAGABI2DRAFT191649(AGABI2DRAFT_191649)
CPUTCONPUDRAFT_81604
SLASERLADRAFT_460044
WSEWALSEDRAFT_31958
WICJ056_003478
PFPPFL1_06787
MRTMRET_3963
MSYMMSY001_2328
PGRPGTG_06436 PGTG_13966
MLRMELLADRAFT_49293
DDIDDB_G0282967(acadsb)
DPPDICPUDRAFT_44750
DFADFA_08597(acadsb)
ACANACA1_384630
TGOTGME49_266270
PTIPHATRDRAFT_20310
FCYFRACYDRAFT_187779(ACD2)
TPSTHAPSDRAFT_269127(ACD3)
AAFAURANDRAFT_58548
PIFPITG_06732 PITG_15615
PSOJPHYSODRAFT_350120 PHYSODRAFT_351306
SPARSPRG_03679
EHXEMIHUDRAFT_464665
GTTGUITHDRAFT_156886
LMALMJF_35_2730
LIFLINJ_35_2780
LDOLDBPK_352780
LMILMXM_34_2730
LBZLBRM_34_2630
LPANLPMP_342570
NGRNAEGRDRAFT_56367
PALLUYA_22885
KAKKalk_08120
GPBHDN1F_19750(acdH)
RPJN234_25705
CUHBJN34_36180
REUReut_C6425
COXE0W60_28530
BGEBC1002_5761
AKATKWG_20020
ODIODI_R3782
PARKLSG25_06695
HTNKI616_03445
SIMPC6571_14795
STHMIS481_03160
DMADMR_42700
DCBC3Y92_01775
DMLDmul_28490(acdA10)
DALDalk_4346
DATHRM2_10010(acd3)
DTOTOL2_C06730(AcdA)
DOVDSCO28_50220(acdA)
DWDDSCW_44620(acdA)
DALKDSCA_44210(acdA_2)
DLIdnl_30090(acdA2)
DMMdnm_037100(acdA3)
DTIDesti_2061
DBRDeba_1947
PCAYFRD00_04700
XDIEZH22_08990
MNOMnod_8045
PGVSL003B_1080(acdH)
SUFLFIL70_14525
AOZHUE56_26240
KPULGXN76_04315
MTURv2500c(fadE19)
MTVRVBD_2500c
MTCMT2575
MRAMRA_2526(fadE19)
MTFTBFG_12522
MTBTBMG_01471
MTKTBSG_01482
MTZTBXG_001458
MTGMRGA327_15415
MTECCDC5079_2304
MTURCFBS_2649(fadE19)
MTLCCDC5180_2276
MTOMTCTRI2_2546(fadE19)
MTDUDA_2500c(fadE19)
MTNERDMAN_2750(fadE19)
MTJJ112_13410
MTUBMT7199_2531
MTUCJ113_17390
MTUEJ114_13370
MTXM943_12910
MTUHI917_17645
MTULTBHG_02437
MTUTHKBT1_2640(fadE19)
MTUUHKBT2_2643(fadE19)
MTQHKBS1_2647(fadE19)
MBOBQ2027_MB2528C(fadE19)
MBTJTY_2514(fadE19)
MBMBCGMEX_2512c(fadE19)
MBKK60_025980
MBXBCGT_2338
MAFMAF_25150(fadE19)
MMICRN08_2771
MCEMCAN_25391(fadE19)
MCQBN44_50491(fadE)
MCVBN43_40166(fadE)
MCXBN42_40456(fadE)
MCZBN45_50884(fadE)
MPAMAP_2312c(fadE19)
MAOMAP4_1511
MAVIRC58_07510
MAVURE97_07510
MITOCO_17410
MIAOCU_17600
MIDMIP_02453
MYOOEM_15430
MCHIAN480_08560
MIROCQ_15050
MMALCKJ54_07445
MLPMLM_2830
MMANMMAN_24270(fadE19)
MSAMycsm_04392
MMCMmcs_3629
MKMMkms_3702
MJLMjls_3634
MMIMMAR_3847(fadE19)
MMAEMMARE11_37330(fadE19)
MMMW7S_07370
MLIMULP_04093(fadE19)
MKNMKAN_05615
MYVG155_20205
MYEAB431_21075
MGOAFA91_16940
MHADB586_08605
MDXBTO20_11080
MSHGMSG_03512(fadE19)
MFJMFLOJ_51830(fadE19)
MSTOMSTO_56040(fadE19)
MSIMMSIM_41300(fadE19)
MSAKMSAS_17830(fadE19)
MKUI2456_18485
MGROFZ046_23910
MXEMYXE_17680
MNVMNVI_02190
MPAGC0J29_21330
MNMMNVM_04810(fadE19)
MGORH0P51_19345
MCOOMCOO_15620
MBAIMB901379_03415(mmgC_14)
MSEOMSEO_23110(fadE19)
MPSEMPSD_39080(fadE19)
MSHOMSHO_30710(fadE19)
MHEKJMUB5695_01851
MGAUMGALJ_24700
MLJMLAC_10850(fadE19)
MBRDMBRA_33150
MSHJMSHI_22950(fadE19)
MKRMKOR_02780
MDFK0O62_20010
MMAMK3U93_16635
MHOLK3U96_08965
MHERK3U94_07695
MSENK3U95_09765
MPAEK0O64_20615
MSPGF6B93_15760
MOTLTS72_05610
MSMMSMEG_4715
MSGMSMEI_4598
MSBLJ00_23320
MSNLI99_23325
MSHLI98_23330
MVAMvan_4089
MGIMflv_2554
MSPMspyr1_19830
MCBMycch_3532
MNED174_19725
MYNMyAD_19345
MFTXA26_41210
MPHLMPHLCCUG_03665(acdA_10)
MVQMYVA_3888
MRHMycrhN_4090
MTHN4412656_02958
MHASMHAS_01111(acdA_3)
MDUMDUV_05720
MCHTMCHIJ_30270
MDRMDOR_26720
MAUUNCTC10437_03836
MMAGMMAD_38410
MMORMMOR_24700
MFXMFAL_15540
MAICMAIC_37140
MIJMINS_40260
MALVMALV_53970
MTYMTOK_60960
MPSCMPSYJ_27210
MARZMARA_58870
MGADMGAD_57880
MHEVMHEL_04080
MSARMSAR_47610
MANYMANY_21480
MAUBMAUB_48440
MPOFMPOR_42230
MPHUMPHO_21250
MMUCC1S78_007700
MMATMMAGJ_77830
MBOKMBOE_32570
MFGK6L26_11550
MSEIMSEDJ_49780
MFLVNCTC10271_01636
MABMAB_4538c
MMVMYCMA_2510
MABBMASS_4565
MABLMMASJCM_4593
MCHEBB28_23155
MIZBAB75_25630
MSTEMSTE_04705
MSAOMYCSP_21130
MSALDSM43276_04379(mmgC_10)
MJDJDM601_1405(fadE19)
MTER4434518_01298(fadE19)
MMINMMIN_29990(fadE19)
MHIBMHIB_08610(fadE19)
ASDAS9A_4351
MPAKMIU77_05660
CRDCRES_1678(fadE8)
CVACVAR_2090
CTERA606_08410
CMDB841_00690
CFNCFAL_08685
CVTB843_04475
COADR71_1563
CHMB842_03730
CEICEPID_03915
CLWCLAC_02630
CSPHCSPHI_02550
CXEFOB82_07985
CPRECsp1_08440(mmgC)
CANSGP473_06915
CLIAC3E79_02240
CAMCI6I65_09920
CUOCUROG_07785(mmgC2)
CKWCKALI_08480(acdA)
CZOIAU67_07130
CCYCSCMU_15500
NFANFA_50390(fadE43)
NFRERS450000_04852
NCYNOCYR_4822
NBRO3I_037975
NNONONO_c68550
NSLBOX37_28920
NSRNS506_01427
NTPCRH09_36275
NOZDMB37_16780
NODFOH10_00750
NAHF5544_40520
NADNCTC11293_06426
NWLNWFMUON74_64330
NIEKV110_37155
NTCKHQ06_09890
NHUH0264_09230
NYALTV02_23770
NGPLTT66_16910
RHARHA1_ro06097
RERRER_18320(fadE)
REYO5Y_08795
REBXU06_09030
RQIC1M55_09270
ROPROP_61540(fadE)
ROAPd630_LPD02739
REQREQ_36020
RPYY013_15655
RBYCEJ39_02160
RHBNY08_3989
RAVAAT18_18350
RFAA3L23_02158(acdA_6)
RHSA3Q41_01220(acdA_3)
RHWBFN03_03355
RRZCS378_07870
RHUA3Q40_00066(acdA_1)
RHQIM25_05610
RHODAOT96_19635
RRT4535765_04751
RCRNCTC10994_02778
RTMG4H71_16440
RKOJWS14_33235
RGOKYT97_09405
GBRGbro_1359
GPOGPOL_c11980
GORKTR9_1273
GOQACH46_04150
GTABCM27_07325
GOCCXX93_17935
GITC6V83_05035
GRUGCWB2_06965(mmgC7)
GOMD7316_01863(acdA_1)
GAVC5O27_20825
GODGKZ92_06605
GAMGII34_04780
GPDGII33_17990
GJIH1R19_06705
GOILK459_03750
SPINKV203_03735
TPRTpau_3319
TSMASU32_04855
DTMBJL86_2295
DITC3V38_01175
DIZCT688_11395
DPCA6048_11965
DLUA6035_10990
TOYFO059_05460
SCOSCO2779(acdH)
SALBXNR_4209
SMASAVERM_5275(fadE4)
SGRSGR_4756
SGBWQO_11760
SCBSCAB_58001(acdH)
SSXSACTE_2272
SVLStrvi_8097
SHYSHJG_4280
SHOSHJGH_4044
SRCM271_31140
SMALSMALA_2810
SSOII1A49_17960
SCTSCAT_1857(yngJ)
SCYSCATT_18520
SFASfla_4110
SBHSBI_06919
SVESVEN_2568
SDVBN159_5499(yngJ1)
SALSSLNWT_2338
STRPF750_2606
SFISFUL_2370
SCIB446_14660
SALUDC74_3256
SALLSAZ_17345
SLVSLIV_23780
SGUSGLAU_12675
SVTSVTN_13735
STREGZL_05657
SCWTU94_12155
SLDT261_5312
SLCSL103_05390
SXISXIM_37940
STRMM444_13330
STRCAA958_10345
SAMBSAM23877_2814(yngJ)
SPRISPRI_4763
SCZABE83_24135
SCXAS200_28470
SRWTUE45_03394(mmgC_7)
STRFASR50_13510
SLEsle_44610(sle_44610)
SRNA4G23_01831(mmgC_3)
SPAVSpa2297_11770
STRTA8713_11110
SCLFBB341_18610
SGSAVL59_41555
STSIA4E84_14650
SKYD0C37_22665
SALWCP975_12485
SGMGCM10017557_53020
SCADDN051_24675
SLSSLINC_3198
SNRSNOUR_26450
SPLULK06_010705
STRDNI25_24960
SNWBBN63_22830
SAUOBV401_17700
SSIAA7J05_23365
SVUB1H20_11010
SPUNBFF78_26595
SGVB1H19_15645
SLAUSLA_2529
SALFSMD44_03078(acdH)
SALJSMD11_4398(acdH)
SLXSLAV_23940(mmgC10)
STROSTRMOE7_14480
SFKKY5_2919
SNZDC008_12255
SGEDWG14_05329(mmgC_4)
SRJSRO_4690
SLKSLUN_14235
SDXC4B68_25760
SGDELQ87_24685
SQZFQU76_10295
SCYAEJ357_16785
SASTCD934_21350
SNQCP978_12885
STIRDDW44_08980
SKACP970_27950
SGZC0216_26170
SVNCP980_21585
SNKCP967_22255
SHAWCEB94_15240
SRKFGW37_11615 FGW37_30950
SFICEIZ62_21560
SGALCP966_13260
SSPODDQ41_07305 DDQ41_20970
SVRCP971_21915
SPADDVK44_10020 DVK44_31300
SFYGFH48_25715
SAQUEJC51_19155
SGFHEP81_05017
SCAVCVT27_10455
SSEOD0Z67_10240
SBYH7H31_23430
SRIMCP984_26170
SSUBCP968_21370
SPHVF9278_16735
SCINCP977_12430
SFUGCNQ36_12620
SPACB1H29_23550
STSUB7R87_10025
SCHACP983_27410
SGXH4W23_14845
SCOECP976_16195
SBATG4Z16_22485
SSPBCP982_16525
SNFJYK04_03391(mmgC_3)
SPLACP981_14255
SBROGQF42_17580
STUIGCM10017668_25000
SATAC5746_15035
SCHFIPT68_13570
SHUNDWB77_04913(mmgC_5)
SHARHUT13_18815
SCYGS1361_15210(mmgC6)
SFEUIM697_07225
SLIAHA039_22765
SDWK7C20_13300
SVDCP969_15010
SCALI6J39_11225
SAUHSU9_011850
SFBCP974_10260
SMOBJ7W19_11375
SPRACP972_13255
SPEUCGZ69_12615
SROIIAG44_26060
SXNIAG42_22720
SGJIAG43_11100
SHKJ2N69_12635
SANUK7396_23280
STRYEQG64_10870
SDDD9753_22575
SACTDMT42_14640
KSKKSE_26850(fadE3)
KABB7C62_10610 B7C62_33350
KAUB6264_16500
KITCFP65_2503
STRIC7M71_009610
YIALO772_08555
LXLKDY119_00180
LEIFHF024_12150
LSEF1C12_00825
MTSMTES_3611(fadE19)
MIMAKG07_03655
MIOAOA12_01415
MIXAB663_002469
MIPAXH82_14605
MCWA8L33_09690
MIHBJP65_01910
MICRBMW26_08255
MAURBOH66_10490
MHOSCXR34_11250
MFOLDXT68_08005
MOOBWL13_01138(mmgC_3)
MLVCVS47_01278(mmgC_2)
MWAE4K62_07985
MPRTET475_17015
MOYCVS54_01933(acdA)
MCAWF6J84_07480
MLZF6J85_07650
MCHNHCR76_09775
MRNK8F61_03920
AGYATC03_12795
AGMDCE93_05550
AGFET445_14410
AARCG127AT_02030
MALKMalAC0309_2110
MYLC3E77_04865
SALCC2138_08100
SALAESZ53_04420
SALDFVA74_11925
PLAPEAO79_15580
AGGC1N71_06400
MANTBHD05_13195
GLNF1C58_10175
ARTArth_1387
ARRARUE_c14430
ARMART_4230
ARLAFL94_04615
AREAL755_07140
AAQAOC05_03650
ARWMB46_03600
ARYATC04_13215
ARZAUT26_06685
ARUASPU41_12135
ARQBWQ92_03025
ARNCGK93_07910
ARXARZXY2_2450
ACRYAC20117_16525
ARTHC3B78_06620
ARTPE5206_16555
AAGINCTC2676_1_00932
AJGKKR91_05590
ARIUM93_01385
PNVJMY29_07230
ACHAchl_1405
APNAsphe3_13780
PSULAU252_00840 AU252_01515 AU252_03420
PSNINIBR502771_18675
PSEYGU243_01350
AAIAARI_09950
GARAOZ07_05275
GCRGcLGCM259_0791
GLUF0M17_04920
GPRJQN66_05045
RSARSal33209_0552
KRHKRH_22750(fadE)
KFVAS188_04445
KRSEQG70_16480
MLUMlut_06870
MICKB1A86_00003325
SATKSA2016_1628
NAEBHE16_04245
AULDCC27_004980
CIGE7744_10495
PAEYKUF55_04830
BCVBcav_3850
BFABfae_00480
BRXBH708_13610
BRVCFK39_08490
BRZCFK38_02525
BSAUDWV08_14380
KSEKsed_08210
DNIHX89_03175
DAYFV141_02650
LMOIVV02_10345
YIMJ5M86_04045
ALXLVQ62_16470
XCEXcel_2102
XYAET471_13705
IVAIsova_0521
IDOI598_1783(acdA)
CETB8281_02365
CCEUCBR64_09530
CFICelf_2557
CELHGXP71_03140
OEKFFI11_002355
ICAIntca_1234
ARSADJ73_16075
JTEASJ30_11400
JLIEXU32_02965
JMEEEW87_003760
TEHGKE56_00515
PHWG7075_10785
PEIH9L10_02495
SERJSGUI_3118
SERWFY030_10620
ORNDV701_17925
ORZFNH13_06405
BLYA2T55_05115
BLINBLSMQ_0975
BRIFDF13_01110
BLUTEW640_13555
BCAUI6G59_07945
AUSIPK37_02155
HALTIM660_07235
MPHMLP_10090(fadE)
MIKFOE78_07035
MICGGJV80_22880
NCANoca_3506
NDKI601_0190(acdA_1)
NOYEXE57_06805
NOIFCL41_12530
NOOFE634_07100
NDPE2C04_13045
NSNEXE58_12870
NANOG5V58_16030
NMESH9L09_04450
NAROCFH99_18485
NPIG7071_09035
NAQUENKNEFLB_01235(acdA_3)
NROK8W59_12415
NOQLN652_18550
PSIMKR76_20105
AERAERYTH_04895
AEZC3E78_13950
AEBC6I20_02275
AEFGEV26_03450
MUZH4N58_15675
KFLKfla_1418
KQIF1D05_27010
TFUTfu_0946
THAONI17_002135
NDANdas_3266
NALB005_0221
NGVCDO52_10860
STRREKD16_09530(mmgC4)
SAIUJ4H86_06040
TCUTcur_1974
ACTWF7P10_37910
AGRAAGRA3207_007075
SROSros_6410
NOABKM31_02295
NOWGBF35_35690
NCXNocox_29015(acdA6)
NGNLCN96_40000
TBITbis_2151
FRAFrancci3_2247
FREFranean1_4050
FRIFraEuI1c_1632 FraEuI1c_5336
FALFRAAL3160
ACEAcel_0405
NMLNamu_1730
NAKEH165_06720
GOBGobs_1474
SENSACE_7037(acdH)
SACGFDZ84_09915
SVISvir_30500
SACCEYD13_16915(mmgC6)
AMDAMED_7920
AMNRAM_36560 RAM_40710
AMMAMES_7012 AMES_7802
AMZB737_7012 B737_7802
AOIAORI_6737(bcd)
AJAAJAP_05435
AMQAMETH_1831(acdH) AMETH_5735(acdH)
AMYCCU254_32175
AMYBBKN51_26965
AABA4R43_22915
AMYYYIM_05860(mmgC3)
AORISD37_06945
AACDLWP59_32995
PDXPsed_1781 Psed_6155
PSEAWY02_14630
PSEEFRP1_27840
PSEHXF36_26125
PSEQAD006_07020
PECQAD017_14835
PHHAFB00_12860
PAUTPdca_64080
PBROHOP40_08245
APRECNX65_30660
AMIAmir_6228
SESPBN6_74940
SSYIEKG83_41780
KALKALB_7771
KPHYAOZ06_47600
LEDBBK82_19875
AHMTL08_22915
ACTIUA75_26745
ACADUA74_26160
AHGAHOG_24035(mmgC2)
ACTAC1701_16415
ALOCRK59629
PMADBAY61_25885
SACEGIY23_21265
STPStrop_0028
SAQSare_0034
MAUMicau_0078
MILML5_0061
MICBMicB006_0069
MTUACSH63_25660
MICHFJK98_00285
MTEMGCE86_25850
MCABHXZ27_00215
MSAGGCM10017556_26500
VMAVAB18032_04720
MCRAID554_14015 ID554_21250
ASEACPL_149(acdH)
AMSAMIS_300
ACTNL083_0037(fadE)
AFSAFR_00195
ACTSACWT_0034
AIHAiant_43140
PLKCIK06_00360
PLABC6361_17380
PLATC6W10_34475
PFLAPflav_069680
PSUUPsuf_032120
VERHUT12_00240
ATLAthai_63270
ASERAsera_12160
PRYPrubr_24600
CATICS0771_12610
DVCDvina_00190
NHYJQS43_00195
CAICaci_2187
SNASnas_6416
NAVJQS30_00695
GLYK3N28_16000
AEYCDG81_21180
EKEEK0264_07800
RXYRxyl_1707
RRDRradSPS_1634
RUBGBA63_11850
BSOLFSW04_24045
CWOCwoe_0232
AFOAfer_0732
ATQGH723_03780
AQZKSP35_00810
IAMHC251_08300
ERZER308_14650
EUZDVS28_a0936
KBSEPA93_40530
SUSAcid_5310
PFERIRI77_14895
CTMCabther_A0832
BLQL21SP5_00851(mmgC_1)
CABYCabys_2853
 » show all
Reference
1  [PMID:6401712]
  Authors
Ikeda Y, Dabrowski C, Tanaka K.
  Title
Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase.
  Journal
J Biol Chem 258:1066-76 (1983)
Reference
2  [PMID:3988734]
  Authors
Komuniecki R, Fekete S, Thissen-Parra J.
  Title
Purification and characterization of the 2-methyl branched-chain Acyl-CoA dehydrogenase, an enzyme involved in NADH-dependent enoyl-CoA reduction in anaerobic mitochondria of the nematode, Ascaris suum.
  Journal
J Biol Chem 260:4770-7 (1985)
Reference
3  [PMID:2736251]
  Authors
Komuniecki R, McCrury J, Thissen J, Rubin N.
  Title
Electron-transfer flavoprotein from anaerobic Ascaris suum mitochondria and its role in NADH-dependent 2-methyl branched-chain enoyl-CoA reduction.
  Journal
Biochim Biophys Acta 975:127-31 (1989)
DOI:10.1016/S0005-2728(89)80210-5
Reference
4  [PMID:10989435]
  Authors
Vockley J, Mohsen al-W A, Binzak B, Willard J, Fauq A.
  Title
Mammalian branched-chain acyl-CoA dehydrogenases: molecular cloning and characterization of recombinant enzymes.
  Journal
Methods Enzymol 324:241-58 (2000)
DOI:10.1016/s0076-6879(00)24236-5
Reference
5  [PMID:11013134]
  Authors
Andresen BS, Christensen E, Corydon TJ, Bross P, Pilgaard B, Wanders RJ, Ruiter JP, Simonsen H, Winter V, Knudsen I, Schroeder LD, Gregersen N, Skovby F
  Title
Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism.
  Journal
Am J Hum Genet 67:1095-103 (2000)
DOI:10.1086/303105
Other DBs
ExplorEnz - The Enzyme Database: 1.3.8.5
IUBMB Enzyme Nomenclature: 1.3.8.5
ExPASy - ENZYME nomenclature database: 1.3.8.5
BRENDA, the Enzyme Database: 1.3.8.5

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