KEGG ENZYME: 1.3.99.33

ENZYME: 1.3.99.33

Entry

EC 1.3.99.33 Enzyme

Name

urocanate reductase;
urdA (gene name)

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors

Sysname

dihydrourocanate:acceptor oxidoreductase

Reaction(IUBMB)

dihydrourocanate + acceptor = urocanate + reduced acceptor [RN:R10330]

Reaction(KEGG)

R10330

Substrate

dihydrourocanate [CPD:C20522];
acceptor [CPD:C00028]

Product

urocanate [CPD:C00785];
reduced acceptor [CPD:C00030]

Comment

The enzyme from the bacterium Shewanella oneidensis MR-1 contains a noncovalently-bound FAD and a covalently-bound FMN. It functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor. The activity has been demonstrated with the artificial donor reduced methyl viologen.

History

EC 1.3.99.33 created 2013

Pathway

ec00340

Histidine metabolism

Orthology

K17363

urocanate reductase

Genes

CAMA:

F384_13015

VHA:	VIBHAR_05539

VCA:	M892_23855

VHR:	AL538_25370

VOW:	A9237_19860

VGA:	BSQ33_13175 BSQ33_15260

VSH:	BSZ05_19580

VAF:	D1115_19610

VSR:	Vspart_01386(urdA_1) Vspart_01796(urdA_2)

VZI:	G5S32_18720

SON:

SO_4620

SBM:	Shew185_4193

SBN:	Sbal195_4325

SBT:	Sbal678_4357

SPC:	Sputcn32_3795

SHP:	Sput200_0127

SSE:

Ssed_0694

SPL:

Spea_3574

SHN:	Shewana3_4004

SHW:	Sputw3181_0118

SHL:

Shal_2847

SWD:

Swoo_3912

SHF:	CEQ32_15300

SBJ:	CF168_20210

SHEW:

CKQ84_06850

SALG:

BS332_06385

SBK:	SHEWBE_1046(urdA)

SCAA:

TUM17387_37640(urdA)

GAP:	GAPWK_0254

CDIZ:

CEDIAZO_01025(namA_1)

SUTT:

SUTMEG_08670(sdhA_1) SUTMEG_09080 SUTMEG_09730 SUTMEG_09860 SUTMEG_10420 SUTMEG_10550(urdA_1) SUTMEG_10820 SUTMEG_10850(sdhA_2) SUTMEG_11420 SUTMEG_11920 SUTMEG_12430(urdA_2) SUTMEG_12800 SUTMEG_12940 SUTMEG_14070 SUTMEG_14190(urdA_3) SUTMEG_17280(sdhA_3)

SUTK:

FG381_00090 FG381_01030 FG381_03995 FG381_04045 FG381_04120 FG381_10100 FG381_10115 FG381_11010 FG381_12355

SWS:	I6J16_00840 I6J16_01155 I6J16_01505 I6J16_01680 I6J16_01685 I6J16_01760 I6J16_02170 I6J16_02190 I6J16_03240 I6J16_03735 I6J16_04100 I6J16_05325 I6J16_05580 I6J16_06510 I6J16_06560 I6J16_07065 I6J16_07970 I6J16_08350 I6J16_08370

BBAY:

A4V04_02335 A4V04_02340 A4V04_02370 A4V04_02375 A4V04_03975 A4V04_05365 A4V04_08680 A4V04_08930 A4V04_08935 A4V04_09115 A4V04_09190 A4V04_10310 A4V04_10315 A4V04_10850 A4V04_12970

DAL:

Dalk_0748

DOV:	DSCO28_43500(urdA)

ADE:

Adeh_2096

ACP:	A2cp1_1861

ANK:	AnaeK_1782

SER:

SEP:

SEPP:

SEPS:

SLG:	SLGD_00224

SLN:	SLUG_02230

SSIF:

AL483_10675

GEQ:	CG018_00505

BLR:	BRLA_c010270

BRW:	GOP56_21105

PTA:	HPL003_01965

POD:	PODO_03480

PAEF:

R50345_03355 R50345_26125

PAEJ:

H70737_03570

PIH:	UB51_06430

PLUT:

EI981_16270

PBAC:

HUB98_26735

LPK:	LACPI_0686(fccA1)

LRN:	CMV25_10335

LCAR:

BHS00_07215

LPAA:

BHS01_08105

SMU:

SMU_180

SMC:	SmuNN2025_0152

SMUT:

SMUGS5_00790

SMJ:	SMULJ23_0173

SMUA:

SMUFR_0150(frdA)

SUB:	SUB0908 SUB1360

SGA:	GALLO_1929

SGG:	SGGBAA2069_c18810

SGT:

SGGB_1913

STK:	STP_0733 STP_1198

STB:

SGPB_1754

SCP:	HMPREF0833_10770

SCF:	Spaf_0869 Spaf_1344(frdA)

SMN:	SMA_1833(ifcA)

SIF:

Sinf_1644

STV:	V470_10250

SPAT:

A0O21_07025 A0O21_07075

SSOB:

DK181_06480

SRAT:

FY406_03685

STRG:

SRT_01730

SMEN:

SAMEA4412692_1366(fccA)

SCHJ:

DDV21_003160 DDV21_008990

SPOC:

NCTC10925_00464

LJO:

LJ_0051

LJF:	FI9785_114

LJH:

LJP_0059

LJN:	T285_00310

LAC:

LAD:

LDB:

LBU:

LDE:	LDBND_0097

LDL:

LBU_0089

LGA:	LGAS_0049 LGAS_1072

LHL:

LBHH_1321

LCR:	LCRIS_00614(frdA1) LCRIS_00618

LAM:	LA2_00360 LA2_04165

LAI:	LAC30SC_00280 LAC30SC_03955

LAY:	LAB52_00295 LAB52_03950

LKE:	WANG_0866 WANG_1634 WANG_p1003

LAW:	LACWKB8_0103 LACWKB8_0116

LAE:	LBAT_0078 LBAT_0080

LJE:	BUE77_00575 BUE77_07895

LAMY:

B1745_07375

LPW:	LpgJCM5343_00480(frdA) LpgJCM5343_08760

LKL:	DKL58_00240 DKL58_00435 DKL58_00495

LAPI:

DKL56_00370

LHS:	DLD54_00570

LTA:	H1A07_00270

LUU:	H4B44_00465

LPL:

lp_1425

LPJ:

JDM1_1191

LPT:	zj316_1469

LPR:	LBP_cg1088

LPZ:

Lp16_1092

LPB:	SH83_05895

LPX:	ASU28_05785 ASU28_14090

LPG:	BB562_10265

LFE:

LAF_0986

LFR:

LC40_0640

LFF:

LBFF_1078

LOR:	AYI71_14025

LGAS:

LG045_03685

LNG:	BSQ50_05310

LHW:	BSQ49_01200

LMAL:

LM596_00725 LM596_01000 LM596_01430

LCU:	PL11_000170

LSUA:

H3M12_06600

LSL:	LSL_1794(sdhA)

LSI:	HN6_01570(sdhA)

LSJ:

LSJ_2085

LAGL:

BEN83_08220

LACA:

LAC1533_0308

LPD:	AYR62_06325 AYR62_12100

LROS:

LROSL1_0221

LGN:	ABM34_07810

LALW:

BTM29_03960

LALI:

LA20249_05385

LFT:	FG051_00765

CPAB:

G6534_11420

LDX:	LH506_03660

ECAS:

ECBG_01227 ECBG_02589

EGA:	AL523_01535 AL523_05475

EGV:	EGCR1_00865 EGCR1_08750

ERAF:

J9537_10830

VCP:	H9L18_02710

VHY:	G7082_08820

AUR:	HMPREF9243_0220 HMPREF9243_0557 HMPREF9243_0993 HMPREF9243_1093

AUN:	AWM73_04395 AWM73_04800 AWM73_06760 AWM73_08065

AUI:	APT62_08825

ASAN:

AWM72_05045 AWM72_07150

ACG:	AWM71_07330

ADC:	FOC79_05320

ABAE:

CL176_02525 CL176_04855 CL176_05320 CL176_06550 CL176_06700 CL176_06745 CL176_06865

CARN:

FPV25_03505

JEH:	EJN90_09320

DPM:	FNV33_02535

CTC:	CTC_00811 CTC_01488 CTC_01847

CTET:

BN906_00849 BN906_01653 BN906_01988

CBE:

Cbei_2056

CBZ:

Cbs_2056

CBEI:

LF65_02225

CSR:	Cspa_c49690

CSB:	CLSA_c08970(urdA)

CACE:

CACET_c23280 CACET_c24890(ifcA)

CFM:	BJL90_19055 BJL90_20575

CDY:	F3K33_10220

CCOH:

SAMEA4530647_0668(ifcA_1) SAMEA4530647_1282(ifcA_2) SAMEA4530647_1605(ifcA_3)

CGAS:

J1C67_18130

AMT:	Amet_0327 Amet_0759 Amet_1551 Amet_3460

AOE:	Clos_0178 Clos_2690

FPRA:

CG447_01865

CPY:

Cphy_3885

CSCI:

HDCHBGLK_03451(urdA)

HSD:

SD1D_1393

ACEL:

acsn021_15800(urdA)

PHX:	KGNDJEFE_00624(urdA) KGNDJEFE_01991(fccA)

DDH:	Desde_0309 Desde_0595

ACAE:

HYG86_05520

TPZ:	Tph_c03790(fccA1)

NTH:	Nther_2466

APR:

Apre_0378

PMIC:

NW74_04630

BULL:

JOS54_04565 JOS54_05205 JOS54_05435 JOS54_05480 JOS54_06790

MGOR:

H0P51_00590

MMOR:

MMOR_56700

CCYS:

SAMEA4530656_2667

CCU:	Ccur_01540 Ccur_10160 Ccur_13430 Ccur_13640

ELE:	Elen_0107 Elen_0488 Elen_2653 Elen_2741 Elen_2778

EGD:	GS424_000585 GS424_000690 GS424_002370 GS424_002540 GS424_002840 GS424_003790 GS424_007055 GS424_008060 GS424_014990 GS424_015560 GS424_016195 GS424_016670

AEQ:	AEQU_0802 AEQU_0921 AEQU_0948 AEQU_1715

DDT:	AAY81_06825

CBAC:

JI75_00415 JI75_03430 JI75_07510 JI75_08095

TPHG:

FUT81_01170

TPAV:

HRQ91_05130 HRQ91_07645 HRQ91_08135

SSM:	Spirs_0848 Spirs_3327 Spirs_4289

BHC:	JFL75_00380 JFL75_02885 JFL75_03675 JFL75_10440 JFL75_16795 JFL75_19175

FVA:	FV113G1_05680 FV113G1_07820 FV113G1_11890

FUL:	C4N20_02440 C4N20_03460 C4N20_11790

FMO:	C4N19_09130

IPO:	Ilyop_1577

CAGG:

HYG79_06570

DAP:	Dacet_2523

» show all

Reference

1 [PMID:23078170]

Authors

Bogachev AV, Bertsova YV, Bloch DA, Verkhovsky MI

Title

Urocanate reductase: identification of a novel anaerobic respiratory pathway in Shewanella oneidensis MR-1.

Journal

Mol Microbiol 86:1452-63 (2012)
DOI:10.1111/mmi.12067

Sequence

[son:SO_4620]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.99.33

IUBMB Enzyme Nomenclature:

1.3.99.33

ExPASy - ENZYME nomenclature database:

1.3.99.33

BRENDA, the Enzyme Database:

1.3.99.33

DBGET integrated database retrieval system