KEGG   ENZYME: 1.3.99.33
Entry
EC 1.3.99.33                Enzyme                                 

Name
urocanate reductase;
urdA (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors
Sysname
dihydrourocanate:acceptor oxidoreductase
Reaction(IUBMB)
dihydrourocanate + acceptor = urocanate + reduced acceptor [RN:R10330]
Reaction(KEGG)
R10330
Substrate
dihydrourocanate [CPD:C20522];
acceptor [CPD:C00028]
Product
urocanate [CPD:C00785];
reduced acceptor [CPD:C00030]
Comment
The enzyme from the bacterium Shewanella oneidensis MR-1 contains a noncovalently-bound FAD and a covalently-bound FMN. It functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor. The activity has been demonstrated with the artificial donor reduced methylviologen.
History
EC 1.3.99.33 created 2013
Pathway
ec00340  Histidine metabolism
Orthology
K17363  urocanate reductase
Genes
CAMA: F384_13015
VHA: VIBHAR_05539
VCA: M892_23855
VHR: AL538_25370
VOW: A9237_19860
VGA: BSQ33_13175 BSQ33_15260
VSH: BSZ05_19580
VAF: D1115_19610
SON: SO_4620
SBM: Shew185_4193
SSE: Ssed_0694
SPL: Spea_3574
SHL: Shal_2847
SWD: Swoo_3912
SBK: SHEWBE_1046(urdA)
DAL: Dalk_0748
DOV: DSCO28_43500(urdA)
ADE: Adeh_2096
SER: SERP2381
SEP: SE0195
SEPP: SEB_00124
SEPS: DP17_1268
LPK: LACPI_0686(fccA1)
SMU: SMU_180
SMUA: SMUFR_0150(frdA)
SGT: SGGB_1913
STB: SGPB_1754
SCF: Spaf_0869 Spaf_1344(frdA)
SMN: SMA_1833(ifcA)
SIF: Sinf_1644
LJO: LJ_0051
LJH: LJP_0059
LAC: LBA0064
LAD: LA14_0068
LSL: LSL_1794(sdhA)
LSI: HN6_01570(sdhA)
LSJ: LSJ_2085
LDB: Ldb0125
LBU: LBUL_0105
LDL: LBU_0089
LHL: LBHH_1321
LPL: lp_1425
LPJ: JDM1_1191
LPZ: Lp16_1092
LFE: LAF_0986
LFR: LC40_0640
LFF: LBFF_1078
CBE: Cbei_2056
CBZ: Cbs_2056
CBEI: LF65_02225
CSB: CLSA_c08970(urdA)
CPY: Cphy_3885
CSCI: HDCHBGLK_03451(urdA)
HSD: SD1D_1393
PHX: KGNDJEFE_00624(urdA) KGNDJEFE_01991(fccA)
TPZ: Tph_c03790(fccA1)
APR: Apre_0378
PMIC: NW74_04630
 » show all
Reference
1  [PMID:23078170]
  Authors
Bogachev AV, Bertsova YV, Bloch DA, Verkhovsky MI
  Title
Urocanate reductase: identification of a novel anaerobic respiratory pathway in Shewanella oneidensis MR-1.
  Journal
Mol Microbiol 86:1452-63 (2012)
DOI:10.1111/mmi.12067
  Sequence
[son:SO_4620]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.99.33
IUBMB Enzyme Nomenclature: 1.3.99.33
ExPASy - ENZYME nomenclature database: 1.3.99.33
BRENDA, the Enzyme Database: 1.3.99.33

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