KEGG   ENZYME: 1.3.99.33
Entry
EC 1.3.99.33                Enzyme                                 

Name
urocanate reductase;
urdA (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors
Sysname
dihydrourocanate:acceptor oxidoreductase
Reaction(IUBMB)
dihydrourocanate + acceptor = urocanate + reduced acceptor [RN:R10330]
Reaction(KEGG)
R10330
Substrate
dihydrourocanate [CPD:C20522];
acceptor [CPD:C00028]
Product
urocanate [CPD:C00785];
reduced acceptor [CPD:C00030]
Comment
The enzyme from the bacterium Shewanella oneidensis MR-1 contains a noncovalently-bound FAD and a covalently-bound FMN. It functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor. The activity has been demonstrated with the artificial donor reduced methylviologen.
History
EC 1.3.99.33 created 2013
Pathway
ec00340  Histidine metabolism
Orthology
K17363  urocanate reductase
Genes
CAMA: F384_13015
VHA: VIBHAR_05539
VCA: M892_23855
VHR: AL538_25370
VOW: A9237_19860
VGA: BSQ33_13175 BSQ33_15260
VSH: BSZ05_19580
VAF: D1115_19610
SON: SO_4620
SBM: Shew185_4193
SBN: Sbal195_4325
SBT: Sbal678_4357
SPC: Sputcn32_3795
SHP: Sput200_0127
SSE: Ssed_0694
SPL: Spea_3574
SHN: Shewana3_4004
SHW: Sputw3181_0118
SHL: Shal_2847
SWD: Swoo_3912
SHF: CEQ32_15300
SBJ: CF168_20210
SHEW: CKQ84_06850
SALG: BS332_06385
SBK: SHEWBE_1046(urdA)
GAP: GAPWK_0254
SUTT: SUTMEG_08670(sdhA_1) SUTMEG_09080 SUTMEG_09730 SUTMEG_09860 SUTMEG_10420 SUTMEG_10550(urdA_1) SUTMEG_10820 SUTMEG_10850(sdhA_2) SUTMEG_11420 SUTMEG_11920 SUTMEG_12430(urdA_2) SUTMEG_12800 SUTMEG_12940 SUTMEG_14070 SUTMEG_14190(urdA_3) SUTMEG_17280(sdhA_3)
SUTK: FG381_00090 FG381_01030 FG381_03995 FG381_04045 FG381_04120 FG381_10100 FG381_10115 FG381_11010 FG381_12355
BBAY: A4V04_02335 A4V04_02340 A4V04_02370 A4V04_02375 A4V04_03975 A4V04_05365 A4V04_08680 A4V04_08930 A4V04_08935 A4V04_09115 A4V04_09190 A4V04_10310 A4V04_10315 A4V04_10850 A4V04_12970
DAL: Dalk_0748
DOV: DSCO28_43500(urdA)
ADE: Adeh_2096
ACP: A2cp1_1861
ANK: AnaeK_1782
SER: SERP2381
SEP: SE0195
SEPP: SEB_00124
SEPS: DP17_1268
SLG: SLGD_00224
SLN: SLUG_02230
SSIF: AL483_10675
GEQ: CG018_00505
BLR: BRLA_c010270
BRW: GOP56_21105
PTA: HPL003_01965
POD: PODO_03480
PAEF: R50345_03355 R50345_26125
PAEJ: H70737_03570
PIH: UB51_06430
PLUT: EI981_16270
LPK: LACPI_0686(fccA1)
LRN: CMV25_10335
SMU: SMU_180
SMC: SmuNN2025_0152
SMUT: SMUGS5_00790
SMJ: SMULJ23_0173
SMUA: SMUFR_0150(frdA)
SUB: SUB0908 SUB1360
SGA: GALLO_1929
SGG: SGGBAA2069_c18810
SGT: SGGB_1913
STK: STP_0733 STP_1198
STB: SGPB_1754
SCP: HMPREF0833_10770
SCF: Spaf_0869 Spaf_1344(frdA)
SMN: SMA_1833(ifcA)
SIF: Sinf_1644
STV: V470_10250
SPAT: A0O21_07025 A0O21_07075
SSOB: DK181_06480
SRAT: FY406_03685
LJO: LJ_0051
LJF: FI9785_114
LJH: LJP_0059
LJN: T285_00310
LAC: LBA0064
LAD: LA14_0068
LSL: LSL_1794(sdhA)
LSI: HN6_01570(sdhA)
LSJ: LSJ_2085
LDB: Ldb0125
LBU: LBUL_0105
LDE: LDBND_0097
LDL: LBU_0089
LGA: LGAS_0049 LGAS_1072
LHL: LBHH_1321
LCR: LCRIS_00614(frdA1) LCRIS_00618
LAM: LA2_00360 LA2_04165
LAI: LAC30SC_00280 LAC30SC_03955
LAY: LAB52_00295 LAB52_03950
LKE: WANG_0866 WANG_1634 WANG_p1003
LAW: LACWKB8_0103 LACWKB8_0116
LAE: LBAT_0078 LBAT_0080
LPX: ASU28_05785 ASU28_14090
LOR: AYI71_14025
LPD: AYR62_06325 AYR62_12100
LJE: BUE77_00575 BUE77_07895
LCU: PL11_000170
LAMY: B1745_07375
LAGL: BEN83_08220
LPG: BB562_10265
LACA: LAC1533_0308
LALW: BTM29_03960
LALI: LA20249_05385
LPW: LpgJCM5343_00480(frdA) LpgJCM5343_08760
LDX: LH506_03660
LKL: DKL58_00240 DKL58_00435 DKL58_00495
LPL: lp_1425
LPJ: JDM1_1191
LPT: zj316_1469
LPR: LBP_cg1088
LPZ: Lp16_1092
LPB: SH83_05895
LFE: LAF_0986
LFR: LC40_0640
LFF: LBFF_1078
LNG: BSQ50_05310
LHW: BSQ49_01200
ECAS: ECBG_01227 ECBG_02589
EGA: AL523_01535 AL523_05475
EGV: EGCR1_00865 EGCR1_08750
AUR: HMPREF9243_0220 HMPREF9243_0557 HMPREF9243_0993 HMPREF9243_1093
AUN: AWM73_04395 AWM73_04800 AWM73_06760 AWM73_08065
AUI: APT62_08825
ASAN: AWM72_05045 AWM72_07150
ACG: AWM71_07330
ADC: FOC79_05320
ABAE: CL176_02525 CL176_04855 CL176_05320 CL176_06550 CL176_06700 CL176_06745 CL176_06865
CARN: FPV25_03505
JEH: EJN90_09320
DPM: FNV33_02535
CTC: CTC_00811 CTC_01488 CTC_01847
CTET: BN906_00849 BN906_01653 BN906_01988
CBE: Cbei_2056
CBZ: Cbs_2056
CBEI: LF65_02225
CSR: Cspa_c49690
CSB: CLSA_c08970(urdA)
CACE: CACET_c23280 CACET_c24890(ifcA)
CFM: BJL90_19055 BJL90_20575
CDY: F3K33_10220
AMT: Amet_0327 Amet_0759 Amet_1551 Amet_3460
AOE: Clos_0178 Clos_2690
CPY: Cphy_3885
CSCI: HDCHBGLK_03451(urdA)
HSD: SD1D_1393
PHX: KGNDJEFE_00624(urdA) KGNDJEFE_01991(fccA)
DDH: Desde_0309 Desde_0595
TPZ: Tph_c03790(fccA1)
NTH: Nther_2466
APR: Apre_0378
PMIC: NW74_04630
CCU: Ccur_01540 Ccur_10160 Ccur_13430 Ccur_13640
ELE: Elen_0107 Elen_0488 Elen_2653 Elen_2741 Elen_2778
AEQ: AEQU_0802 AEQU_0921 AEQU_0948 AEQU_1715
DDT: AAY81_06825
CBAC: JI75_00415 JI75_03430 JI75_07510 JI75_08095
TPHG: FUT81_01170
SSM: Spirs_0848 Spirs_3327 Spirs_4289
FVA: FV113G1_05680 FV113G1_07820 FV113G1_11890
FUL: C4N20_02440 C4N20_03460 C4N20_11790
FMO: C4N19_09130
IPO: Ilyop_1577
CAGG: HYG79_06570
DAP: Dacet_2523
 » show all
Reference
1  [PMID:23078170]
  Authors
Bogachev AV, Bertsova YV, Bloch DA, Verkhovsky MI
  Title
Urocanate reductase: identification of a novel anaerobic respiratory pathway in Shewanella oneidensis MR-1.
  Journal
Mol Microbiol 86:1452-63 (2012)
DOI:10.1111/mmi.12067
  Sequence
[son:SO_4620]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.99.33
IUBMB Enzyme Nomenclature: 1.3.99.33
ExPASy - ENZYME nomenclature database: 1.3.99.33
BRENDA, the Enzyme Database: 1.3.99.33

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Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (5313)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (270)   
   KEGG MGENES (5042)   
Protein sequence (3445)   
   UniProt (3439)   
   SWISS-PROT (6)   
DNA sequence (80)   
   GenBank (41)   
   EMBL (39)   
Protein domain (8)   
   InterPro (8)   
All databases (8854)   

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