KEGG   ENZYME: 1.3.99.37
Entry
EC 1.3.99.37                Enzyme                                 

Name
1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase;
crtD (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors
Sysname
dihydroisopentenyldehydrorhodopin:acceptor 3,4-oxidoreductase
Reaction(IUBMB)
(1) dihydroisopentenyldehydrorhodopin + acceptor = isopentenyldehydrorhodopin + reduced acceptor;
(2) dihydrobisanhydrobacterioruberin + acceptor = bisanhydrobacterioruberin + reduced acceptor
Substrate
dihydroisopentenyldehydrorhodopin [CPD:C22058];
acceptor [CPD:C00028];
dihydrobisanhydrobacterioruberin [CPD:C22060]
Product
isopentenyldehydrorhodopin [CPD:C22059];
reduced acceptor [CPD:C00030];
bisanhydrobacterioruberin
Comment
The enzyme, isolated from the archaeon Haloarcula japonica, is involved in the biosynthesis of the C50 carotenoid bacterioruberin. In this pathway it catalyses the desaturation of the C-3,4 double bond in dihydroisopentenyldehydrorhodopin and the desaturation of the C-3',4' double bond in dihydrobisanhydrobacterioruberin.
History
EC 1.3.99.37 created 2015
Orthology
K20611  1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase
Genes
CGU: WA5_0597(CrtI2) WA5_2346(CrtI')
CGT: cgR_0742
CGS: C624_03890
CGG: C629_03890
CGM: cgp_0720(crtI2)
CGJ: AR0_03715 AR0_11650
CGQ: CGLAR1_03575 CGLAR1_11500
CGX: SB89_03330
CDP: CD241_1779(crtI)
CDH: CDB402_1737(crtI)
CDT: CDHC01_1782(crtI)
CDE: CDHC02_1776(crtI)
CDR: CDHC03_1757(crtI)
CDA: CDHC04_1759(crtI)
CDZ: CD31A_1870(crtI)
CDB: CDBH8_1839(crtI)
CDS: CDC7B_1831(crtI)
CDD: CDCE8392_1744(crtI)
CDW: CDPW8_1843(crtI)
CDV: CDVA01_1718(crtI)
CDIP: ERS451417_01871(crtI)
CAR: cauri_2129(crtI)
CPL: Cp3995_2146(crtI2)
CPG: CP316_10715(crtI)
CPP: CpP54B96_2115(crtI2)
CPK: CP1002_10490(crtI)
CPQ: CPC231_10495(crtI)
CPX: CPI19_10515(crtI)
CPZ: CpPAT10_2084(crtI2)
COR: Cp267_2158(crtI2)
COP: CP31_10930(crtI)
COS: Cp4202_2072(crtI2)
COI: CPCIP5297_10730(crtI)
COE: CP258_10730(crtI)
COU: CP162_10720(crtI)
CPSE: CPTA_00491
CPSU: CPTB_01040
CPSF: CPTC_00708
CUL: CULC22_02325(crtI)
CUC: CULC809_02168(crtI)
CUE: CULC0102_2322(crtI)
CUN: Cul210932_2310(crtI)
CUS: CulFRC11_2181(crtI)
CUQ: Cul210931_2264(crtI)
CUZ: Cul05146_2304(crtI)
CUJ: CUL131002_2212(crtI)
CVA: CVAR_0536(crtI)
CTER: A606_02395
CGY: CGLY_13265(crtI)
CSX: CSING_11005(crtI)
CMQ: B840_00360(crtI)
CKU: UL82_01440(crtI)
CCJ: UL81_01090(crtI2)
CMV: CMUST_03145(crtI2)
CEI: CEPID_09015(crtI)
CUT: CUTER_00095(crtI)
CSP: WM42_1946(crtI)
CPHO: CPHO_02265
CGV: CGLAU_04265(crtN)
CAQU: CAQU_09170
CAMG: CAMM_11150
CMIN: NCTC10288_00437(crtI)
CPEG: CPELA_00960(carA1)
CEE: CENDO_09935(carA2)
CSAN: E3227_00050(crtI)
GBR: Gbro_2545
GOR: KTR9_4487
GRU: GCWB2_22475(carA2)
GOM: D7316_03183(carA2_2)
GOD: GKZ92_21465(crtI)
LXL: KDY119_02695(crtI)
LEIF: HF024_11775(crtI)
CMI: CMM_2887(crtBI)
CMS: CMS2607
CMC: CMN_02853(crtBI)
MTS: MTES_3131
MFOL: DXT68_12225(crtI)
MOO: BWL13_01680(carA2)
MLV: CVS47_01819(carA2)
MWA: E4K62_11395(crtI)
AQG: HRU87_05225(crtI)
RTE: GSU10_13035(crtI)
AUW: AURUGA1_01589(crtN_2)
SALA: ESZ53_08965(crtI)
SALD: FVA74_00845(crtI)
HUM: DVJ78_03065(crtI)
PLAP: EAO79_07295(crtI)
LEU: Leucomu_00180(crtI)
LTR: EVS81_07625(crtI)
HEA: HL652_18475(crtI)
ARM: ART_3630
ARX: ARZXY2_3596(crtI)
AAI: AARI_13730(crtI)
GLU: F0M17_07050(crtI)
KRH: KRH_20830(crtI)
KII: KocCE7_11305(crtI)
KRS: EQG70_15385(crtI)
KOD: HBK84_11245(crtI)
MICK: B1A86_00010485(crtI)
CIG: E7741_02935(crtI)
BCV: Bcav_3491
BSAU: DWV08_16190(crtI)
JDE: Jden_0340
IDO: I598_2038(crtN)
SANW: G7063_11860(crtI)
CFL: Cfla_2891
CFI: Celf_3169
CELZ: E5225_02945(crtI)
CEJ: GC089_03330(crtI)
CELH: GXP71_19965(crtI)
OEK: FFI11_006295(crtI)
PSEI: GCE65_12350(crtI)
JME: EEW87_16425(crtI)
ORN: DV701_13645(crtI)
ORZ: FNH13_18140(crtI)
BLIN: BLSMQ_3115
BRI: FDF13_02195(crtI)
BLUT: EW640_12595(crtI)
NOO: FE634_21985(crtI)
NDP: E2C04_10825(crtI)
SRM: SRM_00920(crtI)
KOS: KORDIASMS9_04390(carA2)
SBAG: UW38_C0001G0645(crtBI)
SRG: XF24_00916(carA2)
MTH: MTH_1807
METC: MTCT_1646
MWO: MWSIV6_0338(crtD)
METE: tca_01745(crtN)
METK: FVF72_02665(crtI)
MTHM: FZP57_01580(crtI)
CDIV: CPM_0973
HAL: VNG_1684G(crtI1) VNG_1755G(crtI2)
HSL: OE_3381R(crtI1) OE_3468R(crtI2)
HHB: Hhub_3180(crtI)
HALH: HTSR_0322(crtI)
HHSR: HSR6_0308(crtI)
HSU: HLASF_0240(crtI)
HSF: HLASA_0240(crtI)
SALR: FQU85_06785(crtI)
HMA: rrnAC0321(crtI2) rrnAC1902(crtI1)
HHI: HAH_1058(crtI1) HAH_2415(crtI2)
HALJ: G9465_16515(crtI)
NPH: NP_0204A(crtI2) NP_4764A(crtD)
NMO: Nmlp_3026(crtI1) Nmlp_3576(crtI2)
HUT: Huta_2373
HALA: Hrd1104_01365(crtI) Hrd1104_03715(crtI)
HALZ: E5139_09960(crtI) E5139_11545(crtI)
HALL: LC1Hm_0581
HSN: DV733_06795(crtI) DV733_07110(crtI)
HWA: HQ_1794A(crtI2) HQ_2863A(crtD)
HWC: Hqrw_1930(crtI2) Hqrw_3257(crtD)
HVO: HVO_2528(crtI)
HME: HFX_2550
HALE: G3A49_16065(crtI)
HAQ: DU484_15070(crtI)
HAJ: DU500_15100(crtI)
HAER: DU502_13080(crtI)
HRA: EI982_09630(crtI) EI982_16645(crtI)
HLM: DV707_06355(crtI)
HALM: FCF25_03150(crtI)
HLA: Hlac_1897
HALB: EKH57_01630(crtI) EKH57_08510(crtI)
HEZZ: EO776_04010(crtI) EO776_05030(crtI) EO776_09980(crtI)
HTU: Htur_2704
HJT: DVR14_14705(crtI)
NMG: Nmag_1001(crtI)
NAT: NJ7G_1612
NVR: FEJ81_05640(crtI)
NPL: FGF80_05295(crtI)
SALI: L593_04765
NBG: DV706_10185(crtI)
NAS: GCU68_01890(crtI)
PAS: Pars_0409
POG: Pogu_1958
 » show all
Reference
1  [PMID:25712483]
  Authors
Yang Y, Yatsunami R, Ando A, Miyoko N, Fukui T, Takaichi S, Nakamura S
  Title
Complete biosynthetic pathway of the C50 carotenoid bacterioruberin from lycopene in the extremely halophilic archaeon Haloarcula japonica.
  Journal
J Bacteriol 197:1614-23 (2015)
DOI:10.1128/JB.02523-14
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.3.99.37
IUBMB Enzyme Nomenclature: 1.3.99.37
ExPASy - ENZYME nomenclature database: 1.3.99.37
BRENDA, the Enzyme Database: 1.3.99.37

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