KEGG   ENZYME: 1.3.99.40
Entry
EC 1.3.99.40                Enzyme                                 

Name
carotenoid chi-ring synthase;
crtU (gene name) (ambiguous);
cruE (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors
Sysname
carotenoid beta-ring:acceptor oxidoreductase/methyltranferase (chi-ring forming)
Reaction(IUBMB)
carotenoid beta-end group + 2 acceptor = carotenoid chi-end group + 2 reduced acceptor [RN:R12116]
Reaction(KEGG)
R12116
Substrate
carotenoid beta-end group [CPD:C21915];
acceptor [CPD:C00028]
Product
carotenoid chi-end group [CPD:C21917];
reduced acceptor [CPD:C00030]
Comment
The enzyme, found in purple sulfur bacteria (Chromatiaceae) and some cyanobacteria, is involved in the biosynthesis of carotenoids that contain chi-type end groups, such as okenone, renierapurpurin, and synechoxanthin.
History
EC 1.3.99.40 created 2018
Orthology
K09879  carotenoid phi-ring synthase / carotenoid chi-ring synthase
Genes
MPUR: MARPU_13345
TSY: THSYN_31050
THIP: N838_26820
GBI: PG2T_09200
AGE: AA314_01168
MBD: MEBOL_006296
CFUS: CYFUS_002285
SAMY: DB32_005179 DB32_008580
HOH: Hoch_2162
MPA: MAP_3075
MAO: MAP4_0725
MAVI: RC58_03535
MAVU: RE97_03540
MAV: MAV_3890
MIT: OCO_37120
MIA: OCU_37200
MID: MIP_05621
MYO: OEM_37780
MIR: OCQ_38330
MMC: Mmcs_5080
MKM: Mkms_5168
MJL: Mjls_5459
MMM: W7S_18580
MSHG: MSG_01535
MVA: Mvan_1580
MGI: Mflv_1844
MPHL: MPHLCCUG_02043(pds_2)
MVQ: MYVA_1335
MTHN: 4412656_00241(pds)
MHAS: MHAS_02867(pds)
MAUU: NCTC10437_01603(pds_1) NCTC10437_04608(pds_2)
MMAG: MMAD_33560
MAIC: MAIC_34480
MTY: MTOK_54220(crtU)
MARZ: MARA_41900(crtU)
MGAD: MGAD_53570
RHB: NY08_3769
RFA: A3L23_01906(pds)
RHS: A3Q41_01459(pds)
RCR: NCTC10994_03817(pds_2)
SCO: SCO0189(crtU)
SALB: XNR_5691
SMA: SAVERM_1019(crtU)
SGR: SGR_56t(crtU2) SGR_6826(crtU) SGR_7083t(crtU3)
SCB: SCAB_5511(crtU)
SCT: SCAT_p0247(crtU)
SFA: Sfla_0352
SHY: SHJG_1675
SALS: SLNWT_1103
STRP: F750_6659
SFI: SFUL_35
STRM: M444_00670
SPRI: SPRI_1987
SLE: sle_65890(sle_65890)
SRN: A4G23_05081(pds)
SLAU: SLA_5754
SGE: DWG14_00741(pds_1)
SRJ: SRO_7452
IDO: I598_1137
SERJ: SGUI_1794
BLIN: BLSMQ_3111
MPH: MLP_17830
TLA: TLA_TLA_02530(pds)
KFL: Kfla_3858
TFU: Tfu_3090
NDA: Ndas_3570
STRR: EKD16_08510(pds)
NML: Namu_2500
SEN: SACE_3271(crtU)
AMD: AMED_4070(crtU)
AMN: RAM_20740
AMM: AMES_4022(crtU)
AMZ: B737_4022(crtU)
AOI: AORI_1550(crtU)
AMQ: AMETH_3322(crtU)
AORI: SD37_26385
PDX: Psed_3342
PSEE: FRP1_10365
PSEH: XF36_09615
PAUT: Pdca_36260(crtU)
SESP: BN6_50870(crtU)
SAQ: Sare_0282
MIL: ML5_2707
ACTN: L083_3346
SYN: sll0254
SYY: SYNGTS_1358(sll0254)
SYT: SYNGTI_1358(sll0254)
SYS: SYNPCCN_1357(sll0254)
SYQ: SYNPCCP_1357(sll0254)
SYP: SYNPCC7002_A1248(crtU)
CYL: AA637_02280(crtU)
CYT: cce_2233
TER: Tery_3577
ARP: NIES39_D01920(crtL)
PAGH: NIES204_24750(crtL)
GVI: gll1923
GLJ: GKIL_2757(crtU)
ANA: alr2785
AVA: Ava_0036
CTHE: Chro_4091
CEO: ETSB_1389
CTE: CT0323
CPC: Cpar_1713
CLI: Clim_1747
PVI: Cvib_0486
PLT: Plut_0435
PPH: Ppha_2256
PAA: Paes_1698
PROC: Ptc2401_01837(petC_1)
 » show all
Reference
1  [PMID:18849428]
  Authors
Graham JE, Bryant DA
  Title
The Biosynthetic pathway for synechoxanthin, an aromatic carotenoid synthesized by the euryhaline, unicellular cyanobacterium Synechococcus sp. strain PCC 7002.
  Journal
J Bacteriol 190:7966-74 (2008)
DOI:10.1128/JB.00985-08
  Sequence
Reference
2  [PMID:22070388]
  Authors
Vogl K, Bryant DA
  Title
Biosynthesis of the biomarker okenone: chi-ring formation.
  Journal
Geobiology 10:205-15 (2012)
DOI:10.1111/j.1472-4669.2011.00297.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.3.99.40
IUBMB Enzyme Nomenclature: 1.3.99.40
ExPASy - ENZYME nomenclature database: 1.3.99.40
BRENDA, the Enzyme Database: 1.3.99.40

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