KEGG ENZYME: 1.4.1.11

ENZYME: 1.4.1.11

Entry

EC 1.4.1.11 Enzyme

Name

L-erythro-3,5-diaminohexanoate dehydrogenase;
L-3,5-diaminohexanoate dehydrogenase

Class

Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor

Sysname

L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)

Reaction(IUBMB)

L-erythro-3,5-diaminohexanoate + H2O + NAD+ = (S)-5-amino-3-oxohexanoate + NH3 + NADH + H+ [RN:R03349]

Reaction(KEGG)

R03349

Substrate

L-erythro-3,5-diaminohexanoate [CPD:C01186];
H2O [CPD:C00001];
NAD+ [CPD:C00003]

Product

(S)-5-amino-3-oxohexanoate [CPD:C03656];
NH3 [CPD:C00014];
NADH [CPD:C00004];
H+ [CPD:C00080]

History

EC 1.4.1.11 created 1976

Pathway

ec00310

Lysine degradation

ec01100

Metabolic pathways

Orthology

K18012

L-erythro-3,5-diaminohexanoate dehydrogenase

Genes

RFR:

Rfer_3890

NOK:	FAY22_04170

AZA:	AZKH_1574(yhdH)

AZI:	AzCIB_1066

ADE:

Adeh_3294

ACP:	A2cp1_3414

AFW:	Anae109_3348

ANK:	AnaeK_3370

MXA:

MXAN_4391

MSD:	MYSTI_04880

MYM:	A176_002511

CCX:	COCOR_03521

MFU:	LILAB_30045

MMAS:

MYMAC_004305

SUR:	STAUR_4751

AGE:	AA314_04545

MBD:	MEBOL_007836

VIN:	AKJ08_2044

SCL:

sce2462

SCU:	SCE1572_14815

CCRO:

CMC5_039320

LLU:	AKJ09_02720

MRM:	A7982_05652

BSED:

DN745_01640

PCAY:

FRD00_14910

NOH:	G5V57_09660

TUM:	CBW65_05635

TAB:	CIG75_01535

LFB:	C1X05_16420

TVU:	AB849_005115

KPUL:

GXN76_15770

KEB:	GXN75_17105

CLS:	CXIVA_06650

CPAT:

CLPA_c31490(kdd)

CPAE:

CPAST_c31490(kdd)

CEU:	A7L45_04290

CARG:

RSJ17_19910

AMT:

Amet_4553

AOE:

Clos_0417

GFE:	Gferi_11535

CRS:	FQB35_13855

FPLA:

A4U99_02925 A4U99_11320

LUA:	D4A81_03620

CST:	CLOST_1383(kdd)

STH:

STH34

DAI:	Desaci_1869

IBU:	IB211_00979

AMIJ:

EQM06_11660 EQM06_11665

AMIC:

Ami3637_09130 Ami3637_09135

ABUT:

Ami103574_15010 Ami103574_15015

EUU:	ADJ67_02630

TTE:

TTE0722

TWI:	Thewi_0851

NTH:	Nther_1883 Nther_1902

HPK:	Hprae_1564

HALS:

D7D81_18040

AFT:	BBF96_12085 BBF96_13605

SPOA:

EQM13_02785

PUF:

UFO1_1637

PFT:

JBW_02728

MBJ:	KQ51_00862(kdd)

TBM:	BK010_00740

TBZ:	BK011_00640

MPHL:

MPHLCCUG_04685(kdd)

ICA:	Intca_1790

ARS:	ADJ73_12520

ORN:	DV701_02925

TEH:	GKE56_04775

PHW:	G7075_06415

NCA:

Noca_2662

NOY:	EXE57_02155

NOI:	FCL41_08525

NOO:	FE634_10510

NDP:	E2C04_09125

NSN:	EXE58_17605

KFL:

Kfla_3604

KQI:	F1D05_03980

TCU:

MMAR:

SESP:

SSYI:

KAL:

KPHY:

LED:	BBK82_41130

ALO:

CRK56462

STP:	Strop_2263

SAQ:

Sare_2382

MAU:	Micau_3120

MIL:

MICB:

MTUA:

MICH:

MTEM:

MCAB:

VMA:	VAB18032_20370

ASE:

ACPL_2805

AMS:	AMIS_47620

ACTN:

L083_3924

AFS:

AFR_21820

ACTS:

ACWT_2741

PLK:	CIK06_14130

PLAB:

C6361_03345

PLAT:

C6W10_18280

PFLA:

Pflav_024740

PSUU:

Psuf_079130(kdd)

SNA:

Snas_3952

FNU:

FN1867

FNC:	HMPREF0946_01615

FNT:	HMPREF0405_01363

FUS:	HMPREF0409_01395

FNE:	FSDG_01974

FHW:	RN87_00400

FPD:	CTM68_06730

FVA:	FV113G1_13770

FUL:	C4N20_15460

FGO:	C4N16_05140

FNF:	BSQ88_03855

FPEI:

C4N17_12365

PGI:

PG_1069

PGN:

PGN_1165

PGT:	PGTDC60_1139

PAH:	Poras_0575

PCRE:

NCTC12858_01515

PCAG:

NCTC12856_01004

PET:	PEIBARAKI_4150

OSP:	Odosp_3172

BUY:	D8S85_10220 D8S85_10225

BACC:

BRDCF_p1072 BRDCF_p1073

MBAS:

ALGA_2256

CACI:

CLOAM1348(kdd)

TLE:

Tlet_1664

PHY:	AJ81_05120

TME:

Tmel_0191

TAF:

THA_423

THP:	BG95_02090

THER:

Y592_02095

FNO:

Fnod_0208

FPE:	Ferpe_0540

FIA:	NA23_03015

PMO:

Pmob_1079

MPZ:	Marpi_0477

MARN:

LN42_02760

KOL:

Kole_0964

KPF:	IX53_04765

MPG:	Theba_2112

MINF:

MESINF_1635(kdd)

ASAC:

ATHSA_1333

PSYT:

DSAG12_00557

» show all

Reference

1 [PMID:4344229]

Authors

Baker JJ, Jeng I, Barker HA.

Title

Purification and properties of L-erythro-3,5-diaminohexanoate dehydrogenase from a lysine-fermenting Clostridium.

Journal

J Biol Chem 247:7724-34 (1972)

Other DBs

ExplorEnz - The Enzyme Database:

1.4.1.11

IUBMB Enzyme Nomenclature:

1.4.1.11

ExPASy - ENZYME nomenclature database:

1.4.1.11

BRENDA, the Enzyme Database:

1.4.1.11

CAS:	37377-90-5

DBGET integrated database retrieval system