KEGG   ENZYME: 1.4.1.14Help
Entry
EC 1.4.1.14                 Enzyme                                 

Name
glutamate synthase (NADH);
glutamate (reduced nicotinamide adenine dinucleotide) synthase;
NADH: GOGAT;
L-glutamate synthase (NADH);
L-glutamate synthetase;
NADH-glutamate synthase;
NADH-dependent glutamate synthase;
glutamate synthase (NADH)
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-glutamate:NAD+ oxidoreductase (transaminating)
Reaction(IUBMB)
2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+ [RN:R00093]
Reaction(KEGG)
Substrate
L-glutamate [CPD:C00025];
NAD+ [CPD:C00003]
Product
L-glutamine [CPD:C00064];
2-oxoglutarate [CPD:C00026];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
A flavoprotein (FMN).
History
EC 1.4.1.14 created 1978
Pathway
ec00250  Alanine, aspartate and glutamate metabolism
ec00910  Nitrogen metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
ec01120  Microbial metabolism in diverse environments
ec01130  Biosynthesis of antibiotics
Orthology
K00264  glutamate synthase (NADH)
Genes
RSS: 109439942
BFO: BRAFLDRAFT_129259
SPU: 754163
APLC: 110978866
SKO: 100371963
DME: Dmel_CG9674(CG9674)
DPO: Dpse_GA21956
DAN: Dana_GF10502
DER: 6543630
DPE: 6601003
DSI: Dsimw501_GD12441(Dsim_GD12441)
DWI: 6645095
MDE: 101893373
AAG: 5565246
AME: 413372
BIM: 100743936
BTER: 100648506
SOC: 105197574
AEC: 105149802
ACEP: 105627138
PBAR: 105424147
HST: 105181045
DQU: 106749864
CFO: 105259420
LHU: 105677426
PGC: 109859877
PCF: 106785427
NVI: 100122109
MDL: 103570096
TCA: 658584
DPA: 109543624
NVL: 108563867
BMOR: 751838(Gogat)
PMAC: 106710933
HAW: 110374537
API: 100158883
DNX: 107164646
CLEC: 106667559
ZNE: 110836732
FCD: 110854382
TUT: 107364085
CEL: CELE_W07E11.1(W07E11.1)
CBR: CBG01975
BMY: Bm1_40910
TSP: Tsp_01351
CRG: 105337796
OBI: 106883777
SHX: MS3_01901
EGL: EGR_01992
EPA: 110251849
ADF: 107355563
ATH: AT5G53460(GLT1)
ALY: ARALYDRAFT_918424(GLT1)
CRB: 17876423
BRP: 103857079
BOE: 106332590
THJ: 104811925
CPAP: 110823143
CIT: 102620225
TCC: 18605743
GRA: 105765457
GHI: 107947250
EGR: 104437859
CAM: 101509615
LJA: Lj0g3v0129059.1(Lj0g3v0129059.1) Lj0g3v0129059.2(Lj0g3v0129059.2) Lj0g3v0254949.2(Lj0g3v0254949.2)
FVE: 101309397
PPER: 18785174
PMUM: 103333633
PAVI: 110767133
ZJU: 107414598
CSV: 101213224
CMO: 103485701
MCHA: 111011404
RCU: 8274353
JCU: 105648339
VVI: 100246868
SLY: 101254281
SPEN: 107013700
SOT: 102580516
NSY: 104244568
NTO: 104098510
INI: 109183410
SIND: 105160371
LSV: 111918005
BVG: 104888263
DOSA: Os05t0555600-01(Os05g0555600)
OBR: 102713634 102721892(NGS)
ATS: 109760356(LOC109760356)
DCT: 110110468
PEQ: 110020245
AOF: 109840747
ATR: 18442390
CRE: CHLREDRAFT_205746(GSN1)
MIS: MICPUN_105473(GLT)
APRO: F751_6615
SCE: YDL171C(GLT1)
ERC: Ecym_4713
KMX: KLMA_50304(GLT1)
NCS: NCAS_0A14190(NCAS0A14190)
NDI: NDAI_0A01860(NDAI0A01860)
TPF: TPHA_0F03070(TPHA0F03070)
TBL: TBLA_0A09100(TBLA0A09100)
TDL: TDEL_0C01870(TDEL0C01870)
PIC: PICST_87428(GLT1)
SPAA: SPAPADRAFT_141734(GLT1)
CAL: CAALFM_C106550WA(GLT1)
CAUR: QG37_03183
SLB: AWJ20_5040(GLT1)
NCR: NCU01744(en(am)-2)
NTE: NEUTE1DRAFT65142(NEUTE1DRAFT_65142)
MGR: MGG_07187
SSCK: SPSK_08269
TRE: TRIREDRAFT_122287(glt1)
MAW: MAC_00032
MAJ: MAA_01819
CMT: CCM_03495
BFU: BCIN_15g02460(Bcglt1)
MBE: MBM_04374
ANI: AN5134.2
ANG: ANI_1_1272064(An07g09920)
PBL: PAAG_12483(PAAG_07998)
ABE: ARB_04215
TVE: TRV_01094
PTE: PTT_08692
SPO: SPAPB1E7.07(glt1)
CNE: CNJ02910
CNB: CNBJ0620
ABP: AGABI1DRAFT104661(AGABI1DRAFT_104661)
ABV: AGABI2DRAFT176670(AGABI2DRAFT_176670)
SLA: SERLADRAFT_357441(NADH-GOGAT)
MGL: MGL_2017
PYO: PY17X_1011100(PY03719)
PCB: PCHAS_101040(PC000809.03.0)
SMIN: v1.2.014989.t1(symbB.v1.2.014989.t1) v1.2.017142.t1(symbB.v1.2.017142.t1) v1.2.017146.t1(symbB.v1.2.017146.t1)
PTI: PHATRDRAFT_51214(GltX)
SPAR: SPRG_06781
 » show all
Taxonomy
Reference
1  [PMID:21790]
  Authors
Boland MJ, Benny AG.
  Title
Enzymes of nitrogen metabolism in legume nodules. Purification and properties of NADH-dependent glutamate synthase from lupin nodules.
  Journal
Eur J Biochem 79:355-62 (1977)
DOI:10.1111/j.1432-1033.1977.tb11816.x
Other DBs
ExplorEnz - The Enzyme Database: 1.4.1.14
IUBMB Enzyme Nomenclature: 1.4.1.14
ExPASy - ENZYME nomenclature database: 1.4.1.14
BRENDA, the Enzyme Database: 1.4.1.14
CAS: 65589-88-0

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