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Entry
EC 1.4.3.10                 Enzyme                                 

Name
putrescine oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
putrescine:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2 [RN:R01151]
Reaction(KEGG)
Substrate
putrescine [CPD:C00134];
O2 [CPD:C00007];
H2O [CPD:C00001]
Product
4-aminobutanal [CPD:C00555];
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD). 4-Aminobutanal condenses non-enzymically to 1-pyrroline.
History
EC 1.4.3.10 created 1976
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K03343  putrescine oxidase
Genes
MDX: BTO20_02740
MAB: MAB_4321
MMV: MYCMA_04160
MABB: MASS_4385
MABL: MMASJCM_4423
MIZ: BAB75_24735
ASD: AS9A_2717
CGL: NCgl0220(Cgl0223)
CGB: cg0274
CGU: WA5_0220
CGM: cgp_0274
CUL: CULC22_02315(puo)
CUC: CULC809_02158(puo)
CUE: CULC0102_2312(puo)
CVA: CVAR_2956(puo)
CGY: CGLY_01565(puo)
CSX: CSING_03535(puo1) CSING_03615(puo2)
CTED: CTEST_03955(puo)
CSP: WM42_0722(puo)
RER: RER_44090(puo)
REY: O5Y_20700
ROP: ROP_56710(puo)
RFA: A3L23_00934(puo_1)
RHS: A3Q41_02419(puo_2)
TPR: Tpau_0682
MTS: MTES_2458
ART: Arth_0040
ARR: ARUE_c00400(puo)
ARM: ART_2629
ARX: ARZXY2_3854(puo)
AAU: AAur_0043(puo)
ACH: Achl_0040
AAI: AARI_27810(puo)
KRH: KRH_00860(puo)
BLIN: BLSMQ_2014
NAL: B005_4495(puo)
KRA: Krad_0838
ASE: ACPL_3219(puo)
ACTS: ACWT_3091
 » show all
Taxonomy
Reference
1  [PMID:4341347]
  Authors
DeSa RJ.
  Title
Putrescine oxidase from Micrococcus rubens. Purification and properties of the enzyme.
  Journal
J Biol Chem 247:5527-34 (1972)
Reference
2
  Authors
Yamada, H.
  Title
Putrescine oxidase (Micrococcus rubens).
  Journal
Methods Enzymol 17B:726-730 (1971)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.10
IUBMB Enzyme Nomenclature: 1.4.3.10
ExPASy - ENZYME nomenclature database: 1.4.3.10
BRENDA, the Enzyme Database: 1.4.3.10
CAS: 9076-87-3

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