Entry
Name
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
glycine:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
glycine + H2O + O2 = glyoxylate + NH3 + H2O2 (overall reaction) [RN:
R00366 ];
(1a) glycine + O2 = 2-iminoacetate + H2O2 [RN:
R07463 ];
(1b) 2-iminoacetate + H2O = glyoxylate + NH3 [RN:
R10245 ]
Reaction(KEGG)
Substrate
Product
Comment
A flavoenzyme containing non-covalently bound FAD. The enzyme from Bacillus subtilis is active with glycine, sarcosine, N-ethylglycine, D-alanine, D-alpha-aminobutyrate, D-proline, D-pipecolate and N-methyl-D-alanine. It differs from EC
1.4.3.3 , D-amino-acid oxidase, due to its activity on sarcosine and D-pipecolate. The intermediate 2-iminoacetate is used directly by EC
2.8.1.10 , thiazole synthase.
History
EC 1.4.3.19 created 2002, modified 2012
Pathway
Orthology
Genes
PLF : PANA5342_p10316(thiO)
PVA : Pvag_pPag30158(thiO)
PPUH : B479_03585 B479_18770
PAMG : BKM19_001415 BKM19_005305(thiO) BKM19_030350
PAVL : BKM03_04760(thiO) BKM03_09055 BKM03_30605
PFE : PSF113_5030(thiO2) PSF113_5641(forZ)
PZA : HU749_025550(thiO) HU749_028640
PMUD : NCTC8068_04524(thiO_2)
PMAB : U0037_03910(thiO) U0037_08870
PFW : PF1751_v1c07460(thiO)
PPUU : PputUW4_04657(thiO)
PALK : PSAKL28_07840 PSAKL28_37690
PRH : LT40_00225 LT40_19825
PUM : HGP31_16710 HGP31_26915(thiO)
PVW : HU752_005250(thiO) HU752_023365
PTRT : HU722_0005085(thiO)
PSAM : HU731_019940(thiO) HU731_024800
PTAE : NCTC10697_00761(thiO)
PCAV : D3880_08135(thiO) D3880_18980(thiO)
KAK : Kalk_05730(thiO) Kalk_19420
AVZ : HWI77_12525 HWI77_17150
SALH : HMF8227_02264(thiO)
CBS : COXBURSA331_A0438(thiO)
LLG : 44548918_01832(thiO_2)
LCJ : NCTC11976_01718(thiO_1)
MISZ : MishRS11D_03850(thiO)
CZA : CYCME_0279 CYCME_2190(thiO)
CYY : CPC19_02085 CPC19_10800
TFRI : Thiofri_00930(thiO)
GAI : IMCC3135_19890(thiO)
HBE : BEI_2587(thiO1) BEI_3330(thiO2)
HAF : C8233_12325(thiO) C8233_15945(thiO)
HAXH : J4377_02330(thiO) J4377_15505(thiO)
CMAI : BFX80_00990 BFX80_04565
CAMH : LCW13_12680(thiO) LCW13_16195(thiO)
COBE : CLAM6_25590 CLAM6_32750
COBB : H2O77_13020(thiO) H2O77_16590(thiO)
COBD : U0O11_12815(thiO) U0O11_16380(thiO)
ALCA : ASALC70_01396(thiO)
REV : HUE57_01430 HUE57_16520(thiO)
NMX : NMA510612_0388(thiO)
NZO : SAMEA4504057_0040(thiO_1)
NANI : NCTC12227_02025(thiO_2)
VFF : VITFI_CDS0570 VITFI_CDS0800
BMV : BMASAVP1_A3224(thiO)
BML : BMA10229_A1773(thiO)
BPM : BURPS1710b_3710(thiO)
BPL : BURPS1106A_3739(thiO)
BUR : Bcep18194_A3336 Bcep18194_A3508
BAC : BamMC406_0159 BamMC406_0337
BCON : NL30_18705 NL30_19860
BLAT : WK25_00655 WK25_01575
BSEM : WJ12_00815 WJ12_01735
BMEC : WJ16_00790 WJ16_01685
BSTG : WT74_01070 WT74_02025
BSER : R0290_00880 R0290_01820
BURK : DM992_02070 DM992_03115
PLG : NCTC10937_00954(thiO_1)
VTR : MYVALT_E_00380(thiO)
ERU : Erum5680(probable_thiO)
ERW : ERWE_CDS_05950(thio)
ERG : ERGA_CDS_05860(thio)
MESJ : MJ8_15090 MJ8_40610
AMIS : Amn_09960 Amn_46730
SMK : Sinme_4215 Sinme_4547
SMX : SM11_pD0094(thiO) SM11_pD0427
SMI : BN406_05180(thiO) BN406_05502
SMEG : C770_GR4pD0094 C770_GR4pD0421
SMEL : SM2011_b20616(thiO)
SMER : DU99_25930 DU99_27595
RHI : NGR_b02920 NGR_c24000
SFH : SFHH103_02267 SFHH103_06476(thiO)
SFD : USDA257_c22930(thiO) USDA257_c47590
SIX : BSY16_241 BSY16_3688(thiO)
SAME : SAMCFNEI73_Ch2734(thiO) SAMCFNEI73_pC1979(thiO)
SINO : SS05631_b50660 SS05631_c25000
ESJ : SJ05684_b42680 SJ05684_c24780
EAK : EKH55_2429 EKH55_3972
EMX : FKV68_15570 FKV68_25350(thiO)
EAD : OV14_3912 OV14_a0741
EAH : FA04_12510 FA04_26725
ATA : AWN88_16585 AWN88_17735
AGR : AGROH133_08028(goxB) AGROH133_08711(thiO)
AGC : BSY240_2923(thiO) BSY240_4205
AGT : EYD00_09720 EYD00_10930(thiO)
ALF : CFBP5473_02500(thiO) CFBP5473_03780
AVQ : HRR99_11080 HRR99_13275(thiO)
AVV : RvVAT039_07070 RvVAT039_42140(thiO)
AVF : RvVAR031_27030 RvVAR031_34630(thiO)
ASAL : CFBP5507_11615(thiO)
RPUS : CFBP5875_10050 CFBP5875_11265(thiO)
ALEG : CFBP4996_11655(thiO)
AVI : Avi_3358 Avi_5918(thiO)
REC : RHECIAT_PC0000246(thiO)
REL : REMIM1_CH03197 REMIM1_PA00090(thiO)
REP : IE4803_CH03372 IE4803_PD00417(thiO)
REI : IE4771_CH03409 IE4771_PB00101(thiO-1) IE4771_PE00434(thiO-2)
RLT : Rleg2_2890 Rleg2_6396
RLB : RLEG3_02930 RLEG3_26350
RLU : RLEG12_07370 RLEG12_25695
RTR : RTCIAT899_CH13280 RTCIAT899_PB01195(thiO2) RTCIAT899_PC03450(thiO1)
RHL : LPU83_3048(goxB) LPU83_4033
RGA : RGR602_CH02779 RGR602_PC01291(thiO)
RPHA : AMC79_CH01148 AMC79_CH03313 AMC79_PD00258(thiO)
RHV : BA939_06065 BA939_07450
RHK : Kim5_CH03417 Kim5_PD00393(thiO)
RJG : CCGE525_14550 CCGE525_27680(thiO) CCGE525_34930(thiO)
RHR : CKA34_16135 CKA34_22180(thiO)
RGR : FZ934_10920 FZ934_15620(thiO)
RAD : CO657_14790 CO657_22735(thiO) CO657_33125(thiO)
ROY : G3A56_12920(thiO) G3A56_14285
RII : FFM53_019095 FFM53_032050(thiO)
RHID : FFM81_005420 FFM81_028085(thiO) FFM81_031415(thiO)
RBQ : J2J99_16475 J2J99_29645(thiO) J2J99_33760(thiO)
RLN : J0663_03305 J0663_22230(thiO) J0663_29815(thiO)
RBAN : J2J98_15825 J2J98_27530(thiO) J2J98_29875(thiO)
RRG : J3P73_18515 J3P73_36315(thiO)
RLS : HB780_03305(thiO) HB780_19655
RROS : D4A92_05720(thiO) D4A92_21135
RAW : NE851_02195(thiO) NE851_08330(thiO) NE851_27440
RSUL : N2599_12215 N2599_25410(thiO)
RLW : RlegWSM1455_15830 RlegWSM1455_27185(thiO)
RRHO : PR018_10430 PR018_27190(thiO)
RTU : PR017_10600 PR017_18365
ARA : Arad_3332 Arad_7396(thiO)
ARO : B0909_01410 B0909_24870(thiO)
RHIZ : QMO80_001473 QMO80_003739 QMO80_006456(thiO)
RHIB : I8E17_11190 I8E17_22090(thiO)
LCC : B488_01050 B488_08360
SZO : K8M09_11995 K8M09_14475(thiO)
SOJ : K6301_10675 K6301_12575(thiO)
SSUM : Q9314_13985(thiO) Q9314_15955
PDES : FE840_001305 FE840_004190(thiO)
BIO : BR141012304_10329(thiO)
OCA : OCAR_5034 OCAR_7028(thiO)
OCG : OCA5_c10650(thiO1) OCA5_c29250(thiO2)
PCAX : AFIC_000770 AFIC_002421(thiO)
VGO : GJW-30_1_02853(hcnC_2)
BHS : BM1374165_00469(thiO)
BTX : BM1374166_00708(thiO)
BEZ : NCTC12898_00426(thiO)
MAQU : Maq22A_c24795(dadA)
MMES : MMSR116_28020(thiO)
MTUN : MTUNDRAET4_2158(thiO)
HNI : W911_07375 W911_07500
FIL : BN1229_v1_4062(thiO)
FIY : BN1229_v1_4048(thiO)
MMYR : MXMO3_01065 MXMO3_03198
PLEO : OHA_1_04357(thiO_2)
PSF : PSE_0093 PSE_0910(thiO)
PPHR : APZ00_04835 APZ00_23660
LAP : ACP90_16605 ACP90_19625
LABT : FIU93_23240 FIU93_26180(hcnC2)
LAGG : B0E33_00025 B0E33_03305
BVY : NCTC9239_02066(thiO)
TSV : DSM104635_01812(hcnC)
SIT : TM1040_0146 TM1040_3650
RDE : RD1_0747(thiO) RD1_0969
RLI : RLO149_c001780 RLO149_c039690(thiO)
PGA : PGA1_c09100(thiO) PGA1_c28970
PGL : PGA2_c08820(thiO) PGA2_c26900
PHP : PhaeoP97_00608 PhaeoP97_00874(thiO)
PPIC : PhaeoP14_00829(thiO) PhaeoP14_02669
PHQ : D1820_00320 D1820_09185
OAT : OAN307_c05430 OAN307_c22850(thiO)
OAR : OA238_c01670 OA238_c18440(thiO1) OA238_c39750(thiO2)
LMD : METH_12790 METH_14960
LEJ : ETW24_13455 ETW24_16580
LAQU : R2C4_05555 R2C4_15070
LCAE : K3721_01970 K3721_11805
CEH : CEW89_04335 CEW89_14580
MALG : MALG_03404 MALG_04800
CON : TQ29_01590 TQ29_09715
YPAC : CEW88_16630 CEW88_22480
YAN : AYJ57_20045 AYJ57_23385
TPRO : Ga0080559_TMP3159 Ga0080559_TMP3565
PABY : Ga0080574_TMP3446 Ga0080574_TMP46
SULD : B5M07_07235 B5M07_15875
SPOT : G6548_03185 G6548_08615
SPSE : SULPSESMR1_03471(thiO) SULPSESMR1_04972(thiO)
RMM : ROSMUCSMR3_01913(dadA)
RID : RIdsm_04627(thiO_1) RIdsm_05438(thiO_2)
ROH : FIU89_13635(thiO1) FIU89_18570(thiO2)
AHT : ANTHELSMS3_02029 ANTHELSMS3_03944
MALU : KU6B_42930 KU6B_49130(thiO_1) KU6B_56880(thiO_2)
HAT : RC74_03655 RC74_08380
PAMI : JCM7686_0113 JCM7686_3055
PYE : A6J80_09960 A6J80_11970
PCON : B0A89_04995 B0A89_11475
PZH : CX676_10705 CX676_20060
PARO : CUV01_07130 CUV01_10730
PAMN : JCM7685_0175(thiO) JCM7685_0644
PARS : DRW48_05090 DRW48_13900(thiO)
PARR : EOJ32_00455 EOJ32_11885
PKD : F8A10_00380 F8A10_10195
PPAN : ESD82_18925 ESD82_21125
PLIA : E4191_04510 E4191_14210
PMAU : CP157_00374(thiO_1) CP157_01363(thiO_2)
RMB : K529_015850 K529_018390
TSCO : R1T40_01350 R1T40_13500
DAA : AKL17_0347 AKL17_2347
THW : BMG03_03175 BMG03_04335
LVS : LOKVESSMR4R_00068(thiO) LOKVESSMR4R_02495(mnmC)
SEDI : EBB79_14470 EBB79_18605
PPSO : QPJ95_09565 QPJ95_14545
HML : HmaOT1_04460 HmaOT1_16745
PSEB : EOK75_06265 EOK75_17765
PPRU : FDP22_00805 FDP22_18250
PAED : G5B38_04655 G5B38_07735
MON : G8E03_11155 G8E03_12805
PALW : PSAL_016710 PSAL_030110(thiO)
CACT : HZ995_07685 HZ995_08915
THAS : C6Y53_14120 C6Y53_15100
RBG : BG454_05855 BG454_07780
SINR : O5O51_01390 O5O51_07200(thiO)
RHP : LPB142_02645 LPB142_15410
MAES : Ga0123461_1320 Ga0123461_1712
MFN : Ga0123462_0674 Ga0123462_1082
MXA : MXAN_4231(thiO) MXAN_4550
MSD : MYSTI_02430 MYSTI_03719 MYSTI_05006
MYM : A176_001492 A176_002347 A176_002669
MFB : MFUL124B02_26055 MFUL124B02_27515
MYX : QEG98_22590(thiO) QEG98_29935
MLAN : JY572_01600 JY572_08030(thiO)
MFU : LILAB_29295 LILAB_30750 LILAB_34835
MMAS : MYMAC_004141 MYMAC_004450 MYMAC_005267
PPAK : JY651_09515 JY651_11275(thiO)
AGE : AA314_04391 AA314_04981 AA314_06226
AVM : JQX13_15120 JQX13_35720
PCAY : FRD00_05265(thiO) FRD00_05640 FRD00_14700(thiO)
PIJ : QEJ31_00790 QEJ31_05280
SAQI : AXG55_08765 AXG55_12740
BAZ : BAMTA208_11765(thiO)
BSON : S101395_03588(thiO)
BFD : NCTC4823_03677(thiO_2)
BGI : BGM20_00060 BGM20_21140
PARG : PspKH34_31150(goxB)
ASED : IRT44_08625(thiO) IRT44_16795(thiO)
APAK : AP3564_10215 AP3564_13740
BLEN : NCTC4824_01711(goxB)
SDP : NCTC12225_02652(thiO)
SPIC : SAMEA4384060_0471(goxB)
BBE : BBR47_08930(thiO) BBR47_28660
BAYD : BSPP4475_08565(thiO) BSPP4475_17365(thiO)
PCHI : PC41400_28390(thiO)
PNK : AASFL403_06195(thiO)
FFE : LSG31_06345(thiO) LSG31_21675(thiO)
MMAE : MMARE11_06670(thiO)
MBAI : MB901379_00605(thiO)
MHEK : JMUB5695_04282(thiO)
MKY : IWGMT90018_07220(thiO)
MPHL : MPHLCCUG_04636(thiO)
MFLV : NCTC10271_04595(thiO_2)
MSAL : DSM43276_04099(thiO)
MTER : 4434518_00384(thiO)
CDIP : ERS451417_00036(thiO)
CUN : Cul210932_1499(thiO)
CUQ : Cul210931_1386(thiO)
CUJ : CUL131002_1420(thiO)
CMIN : NCTC10288_00906(thiO)
CRL : NCTC7448_00655(thiO_2)
NFR : ERS450000_04532(thiO)
NAD : NCTC11293_00324(thiO)
NSPU : IFM12276_59820(thiO)
RPY : Y013_10130 Y013_14250
RANT : RHODO2019_14695(thiO)
SRC : M271_35820 M271_40030
STRE : GZL_00045 GZL_02230 GZL_06409 GZL_09368
SCW : TU94_04935 TU94_09130
SLE : sle_50310(sle_50310)
SALW : CP975_00135 CP975_09240(thiO)
SGM : GCM10017557_60890(thiO)
SGV : B1H19_12465 B1H19_30775
SALJ : SMD11_0210 SMD11_4946(thiO)
STIR : DDW44_03855(thiO) DDW44_15200
SRK : FGW37_08860(thiO) FGW37_32895
SPAD : DVK44_06485(thiO) DVK44_18010
SRIM : CP984_30350(thiO) CP984_38420
SPHV : F9278_10855(thiO) F9278_29750 F9278_37025
SCHA : CP983_04305 CP983_31745(thiO)
SCOE : CP976_10795 CP976_12195(thiO)
STUI : GCM10017668_17570(thiO)
SHUN : DWB77_05622(hcnC_3)
SHK : J2N69_09050(thiO) J2N69_31090(thiO)
SMAO : CAG99_19780 CAG99_22570
SGOB : test1122_03605(thiO)
SXT : KPP03845_100421(thiO) KPP03845_102354(hcnC_1)
SYUN : MOV08_00080 MOV08_29840(thiO)
STRZ : OYE22_26265(thiO) OYE22_31315
SPRF : K4G22_05325(thiO) K4G22_29765(thiO)
PSNI : NIBR502771_11735(thiO)
RDN : HMPREF0733_11309(thiO)
AUL : DCC27_005540 DCC27_005550
PSEK : GCM125_04050 GCM125_04060
PAK : HMPREF0675_3569(thiO)
RAIN : Rai3103_10950(thiO)
NAQU : ENKNEFLB_01630(thiO)
AGRA : AGRA3207_006078 AGRA3207_006783(thiO)
MHAI : OHB01_23795(thiO) OHB01_38310
AAB : A4R43_02340 A4R43_26180
AMYZ : HUW46_05020(hcnC_2)
PHH : AFB00_05140 AFB00_13385
AHM : TL08_02085 TL08_05875
AHG : AHOG_01890(hcnC1) AHOG_05350
ACTU : Actkin_00442(hcnC_1)
STP : Strop_3051 Strop_3888
MSAG : GCM10017556_17380(thiO) GCM10017556_50410
ACTN : L083_0963(thiO) L083_2866
AIH : Aiant_49800 Aiant_51810
PRY : Prubr_15660(thiO) Prubr_36940
DVC : Dvina_10745 Dvina_44275(thiO)
DMAT : Dmats_10350 Dmats_38870(thiO)
GVG : HMPREF0421_20253(thiO)
GVA : HMPREF0424_1286(thiO)
GVH : HMPREF9231_1298(thiO)
JCY : M6B22_00510(thiO) M6B22_06110
BALA : DSM104299_00304(thiO)
SBAE : DSM104329_00307(hcnC_1)
SYD : Syncc9605_2498 Syncc9605_2673
SYE : Syncc9902_2170 Syncc9902_2302
SYR : SynRCC307_2376 SynRCC307_2515
SYNP : Syn7502_00031 Syn7502_03120
SYNR : KR49_08095 KR49_08810
SYND : KR52_02585 KR52_03430
SYH : Syncc8109_2596(thiO) Syncc8109_2743
SYNW : SynWH8103_02706 SynWH8103_02895
PMC : P9515_00541(dadA) P9515_18941
PMG : P9301_00501(dadA) P9301_18941
PMJ : P9211_00541(dadA) P9211_18391
PSEU : Pse7367_1707 Pse7367_3150
PSER : ABRG53_0829(thiO) ABRG53_0901
PGX : OA858_00870(thiO) OA858_01305
CYU : UCYN_06790 UCYN_11480
PPSU : NO713_02915(thiO_thiG)
PRUN : PCC7821_04553(thiO_thiG)
KBS : EPA93_01535(thiO) EPA93_10875(thiO)
KBB : ccbrp13_11320 ccbrp13_64590
TRO : trd_1971 trd_A0682(thiO)
MTAI : Mtai_v1c09420(thiO)
MTAR : DF168_00389(thiO_1)
LCRE : Pla8534_45970(thiO)
PND : Pla175_19720(hcnC) Pla175_51650(mnmC)
PBS : Plabr_2608 Plabr_2896
GIM : F1728_03545(thiO) F1728_26115
GPN : Pan110_21050(hcnC) Pan110_38850
MRI : Mal4_03220 Mal4_11900(hcnC)
PLON : Pla110_14540(hcnC) Pla110_20780
GES : VT84_08715 VT84_22585(hcnC)
GOG : C1280_07205 C1280_16010
GMS : SOIL9_07620 SOIL9_17680
LRS : PX52LOC_03934 PX52LOC_05069
ULI : ETAA1_08180 ETAA1_20610(hcnC)
TSPH : KIH39_11100 KIH39_13195
SACI : Sinac_5203 Sinac_7304
SCOR : J3U87_14025(thiO) J3U87_31870
CHG : AXF12_01350 AXF12_01400
AALG : AREALGSMS7_00703(thiO)
KAN : IMCC3317_23170(mnmC_2)
» show all
Taxonomy
Reference
Authors
Job V, Marcone GL, Pilone MS, Pollegioni L
Title
Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein.
Journal
Sequence
Reference
Authors
Nishiya Y, Imanaka T.
Title
Purification and characterization of a novel glycine oxidase from Bacillus subtilis.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.19
ExPASy - ENZYME nomenclature database: 1.4.3.19