KEGG   ENZYME: 1.4.3.2
Entry
EC 1.4.3.2                  Enzyme                                 

Name
L-amino-acid oxidase;
ophio-amino-acid oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
Sysname
L-amino-acid:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
an L-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 [RN:R01259]
Reaction(KEGG)
Substrate
L-amino acid [CPD:C00151];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
2-oxo carboxylate [CPD:C00161];
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD).
History
EC 1.4.3.2 created 1961
Pathway
ec00250  Alanine, aspartate and glutamate metabolism
ec00270  Cysteine and methionine metabolism
ec00280  Valine, leucine and isoleucine degradation
ec00350  Tyrosine metabolism
ec00360  Phenylalanine metabolism
ec00380  Tryptophan metabolism
ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ec00950  Isoquinoline alkaloid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K03334  L-amino-acid oxidase
Genes
HSA: 259307(IL4I1)
PTR: 456223(IL4I1)
PPS: 100980850(IL4I1)
GGO: 101153847(IL4I1)
PON: 100936174(IL4I1)
NLE: 100588082(IL4I1)
MCC: 719114(IL4I1)
MCF: 102115096(IL4I1)
CSAB: 103225935 103235062(IL4I1)
CATY: 105595313(IL4I1)
PANU: 101019624(IL4I1) 110742566
RRO: 104667273(IL4I1)
RBB: 108535617 108535810(IL4I1)
TFN: 117091607(IL4I1)
PTEH: 111520078(IL4I1)
CJC: 100393511(IL4I1)
SBQ: 101036047(IL4I1)
MMUR: 105865621(IL4I1)
MMU: 100328588(Il4i1b) 100470(Lao1) 14204(Il4i1) 73988(4930438A08Rik)
RNO: 100360621(Il4i1) 287305(RGD1308564) 298483(Lao1)
HGL: 101710424(Il4i1)
OPI: 101528013(IL4I1) 101530470
TUP: 102481575 102484685(IL4I1)
CFA: 482436 484371(IL4I1)
VVP: 112908249 112931512(IL4I1)
VLG: 121478904(IL4I1) 121481065
AML: 100476680
UMR: 103657267(IL4I1) 103670918
UAH: 113243274(IL4I1) 113254224
ORO: 101367095(IL4I1) 101374427
MPUF: 101679701 101682166(IL4I1)
EJU: 114199615(IL4I1) 114224205
MLX: 117998280(IL4I1) 118019531
FCA: 101100683(IL4I1) 111561629
PYU: 121017594 121018799(IL4I1)
PBG: 122479388 122493838(IL4I1)
PTG: 102958405(IL4I1) 107179172
PPAD: 109253035(IL4I1) 109254834
AJU: 106970164 106983121(IL4I1)
HHV: 120236036 120240706(IL4I1)
BTA: 104968452(IL4I1) 782545
BOM: 102265076(IL4I1) 102281829
BIU: 109556898 109572132(IL4I1)
BBUB: 102390358 102390534(IL4I1)
CHX: 102183203 102186899(IL4I1)
OAS: 101103614 105602079(IL4I1)
ODA: 120856603 120872106(IL4I1)
CCAD: 122420530(IL4I1) 122429212
BACU: 103000198(IL4I1) 103011548
LVE: 103085233 103091507(IL4I1)
OOR: 101272245 101278148(IL4I1)
DLE: 111175407 111180588(IL4I1)
PCAD: 102976825(IL4I1) 102988769
MYD: 102756117
MMYO: 118655360(IL4I1) 118675115
MNA: 107531789(IL4I1) 107544363
PKL: 118712191(IL4I1) 118723116
HAI: 109391026(IL4I1)
DRO: 112310093(IL4I1)
SHON: 118977598(IL4I1)
AJM: 119050609(IL4I1) 119052159
MMF: 118638866(IL4I1)
PALE: 102888858 102897392(IL4I1)
PGIG: 120607388 120615521(IL4I1)
RAY: 107500425(IL4I1) 107508277
MJV: 108383350(IL4I1)
TOD: 119236741 119249626(IL4I1)
OAA: 100079395(IL4I1)
GGA: 417039(IL4I1)
PCOC: 116236713(IL4I1)
MGP: 100540143(IL4I1)
CJO: 107321571(IL4I1)
NMEL: 110406676(IL4I1)
APLA: 101790142(IL4I1)
ACYG: 106049930(IL4I1)
TGU: 100222394(IL4I1)
SCAN: 103824938(IL4I1)
PMOA: 120503973(IL4I1)
OTC: 121338701(IL4I1)
PRUF: 121359413(IL4I1)
GFR: 102037637(IL4I1)
FAB: 101808392(IL4I1)
PHI: 102109935(IL4I1)
PMAJ: 107198862(IL4I1)
CCAE: 111936793(IL4I1)
CCW: 120412144(IL4I1)
FPG: 106112282(IL4I1)
FCH: 102046121(IL4I1)
CLV: 102086260(IL4I1)
EGZ: 104133949(IL4I1)
NNI: 104011855(IL4I1)
PADL: 103922928(IL4I1)
AAM: 106482065(IL4I1)
AROW: 112978516(IL4I1)
DNE: 112992962(IL4I1)
AMJ: 102565465 102573609(IL4I1)
XLA: 108696562 108696644(il4i1.L)
XTR: 100493881(il4i1) 100496394
DRE: 337166(si:dkey-40g16.6)
IPU: 108277784(il4i1)
PHYP: 113532631(il4i1)
EEE: 113579601(il4i1)
TRU: 101072153 101072660(il4i1)
NCC: 104942625
CGOB: 115017826(il4i1) 115024066
GAT: 120814801(il4i1) 120823029
PPUG: 119209117(il4i1) 119222932
CSEM: 103377764(il4i1)
XGL: 120792272(il4i1) 120797257
HCQ: 109510681
BPEC: 110161951(il4i1)
MALB: 109954170(il4i1)
ELS: 105024042(il4i1)
SFM: 108928687(il4i1)
PKI: 111833916(il4i1)
AANG: 118209514(il4i1)
PSPA: 121303996(il4i1) 121324337
EAF: 111712914
BGT: 106053389
 » show all
Reference
1
  Authors
Meister, A. and Wellner, D.
  Title
Flavoprotein amino acid oxidase.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 609-648.
Reference
2  [PMID:13843884]
  Authors
WELLNER D, MEISTER A.
  Title
Crystalline L-amino acid oxidase of Crotalus adamanteus.
  Journal
J Biol Chem 235:2013-8 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 1.4.3.2
IUBMB Enzyme Nomenclature: 1.4.3.2
ExPASy - ENZYME nomenclature database: 1.4.3.2
BRENDA, the Enzyme Database: 1.4.3.2
CAS: 9000-89-9

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