Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy

pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)

(1) pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + H2O2 [RN:R00277];
(2) pyridoxine 5'-phosphate + O2 = pyridoxal 5'-phosphate + H2O2 [RN:R00278]

R00277 R00278;
(other) R01710 R01711
Reaction

pyridoxamine 5'-phosphate [CPD:C00647];
H2O [CPD:C00001];
O2 [CPD:C00007];
pyridoxine 5'-phosphate [CPD:C00627]

A flavoprotein (FMN). In Escherichia coli, the cofactor pyridoxal 5'-phosphate is synthesized de novo by a pathway that involves EC 1.2.1.72 (erythrose-4-phosphate dehydrogenase), EC 1.1.1.290 (4-phosphoerythronate dehydrogenase), EC 2.6.1.52 (phosphoserine transaminase), EC 1.1.1.262 (4-hydroxythreonine-4-phosphate dehydrogenase), EC 2.6.99.2 (pyridoxine 5'-phosphate synthase) and EC 1.4.3.5 (with pyridoxine 5'-phosphate as substrate). N4'-Substituted pyridoxamine derivatives are also oxidized in reaction (1) to form pyridoxal 5-phosphate and the corresponding primary amine.

EC 1.4.3.5 created 1961, modified 2006