KEGG ENZYME: 1.5.1.11

ENZYME: 1.5.1.11

Entry

EC 1.5.1.11                 Enzyme

Name

D-octopine dehydrogenase;
D-octopine synthase;
octopine dehydrogenase;
octopine:NAD+ oxidoreductase;
ODH;
2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)

Class

Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)

Reaction(IUBMB)

N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH + H+ [RN:R00562]

Reaction(KEGG)

R00562

Substrate

N2-(D-1-carboxyethyl)-L-arginine [CPD:C04137];
NAD+ [CPD:C00003];
H2O [CPD:C00001]

Product

L-arginine [CPD:C00062];
pyruvate [CPD:C00022];
NADH [CPD:C00004];
H+ [CPD:C00080]

Comment

In the reverse direction, acts also on L-ornithine, L-lysine and L-histidine.

History

EC 1.5.1.11 created 1972

Pathway

ec00330

Arginine and proline metabolism

ec01100

Metabolic pathways

Orthology

K23233

D-octopine dehydrogenase

Genes

LGI:	LOTGIDRAFT_202998

PVUL:

126817613 126817614

LSAX:

138954702 138979639

GAE:	121375148 121375171 121375569

HRF:	124130929 124130932 124135646 124141222 124141236 124143581

HRJ:	124269418 124275434 124275436 124275497 124279633 124285795 124285908

HASI:

137281013 137290908 137290961 137291576 137291937 137292024

HCRA:

139447505 139448735 139479363 139480015 139480152 139480207

CRG:	105331524 105331526 105331583 105342796

CANU:

128165198 128166457 128167379 128167958

CVN:	111118735 111118741 111118934 111119819 111119820 111120370 111122144 111122441

OED:	125670414 125670567 125671462

MYI:	110451252 110457910

PMAX:

117318100 117325339 117332653

AIRR:

138324799 138325198 138328231 138331180

MCAF:

127699589 127704786 127704952 127726270 127726287

MMER:

123524662 123525369 123525370

RPHI:

132733507 132758115 132758118 132760106

DPOL:

127862474 127862524

MAEA:

128213050 128213110 128213168 128215533

OBI:	106869612 106880801

OSN:	115219799 115219972

LJP:

135470748

LLON:

135484369 135484371 135499408

MCAZ:

138024866

HSY:

130612781

» show all

Reference

Authors

Kemp JD, Hack E, Sutton DW, El-Wakil M.

Title

Unusual amino acids and their relationship to tumorigenesis.

Journal

Proc Int Conf Plant Pathol Bact 4th:183-188 (1979)

Reference

2 [PMID:4310628]

Authors

van Thoai N, Huc C, Pho DB, Olomucki A.

Title

[Octopine dehydrogenase. Purification and catalytic properties]

Journal

Biochim Biophys Acta 191:46-57 (1969)
DOI:10.1016/0005-2744(69)90313-1

Other DBs

ExplorEnz - The Enzyme Database:

1.5.1.11

IUBMB Enzyme Nomenclature:

1.5.1.11

ExPASy - ENZYME nomenclature database:

1.5.1.11

BRENDA, the Enzyme Database:

1.5.1.11

CAS:	37256-27-2

All links

Protein sequence (53)   
   UniProt (37)   
   SWISS-PROT (5)   
   RefSeq(pep) (7)   
   PDBSTR (4)   
DNA sequence (123)   
   RefSeq(nuc) (63)   
   GenBank (30)   
   EMBL (30)   
3D Structure (4)   
   PDB (4)   
Protein domain (5)   
   InterPro (5)   
All databases (185)   

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