Entry |
|
Name |
formyltetrahydrofolate dehydrogenase;
10-formyl tetrahydrofolate:NADP oxidoreductase;
10-formyl-H2PtGlu:NADP oxidoreductase;
10-formyl-H4folate dehydrogenase;
N10-formyltetrahydrofolate dehydrogenase;
10-formyltetrahydrofolate dehydrogenase
|
Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
10-formyltetrahydrofolate:NADP+ oxidoreductase
|
Reaction(IUBMB) |
10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+ [RN: R00941]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
History |
EC 1.5.1.6 created 1972
|
Pathway |
|
Orthology |
K00289 | formyltetrahydrofolate dehydrogenase |
|
Genes |
HSA: | 10840(ALDH1L1) 160428(ALDH1L2) |
PTR: | 452195(ALDH1L2) 460655(ALDH1L1) |
PPS: | 100978685(ALDH1L2) 100989341(ALDH1L1) |
GGO: | 101134299(ALDH1L1) 101139377(ALDH1L2) |
PON: | 100172380(ALDH1L1) 100459691(ALDH1L2) |
PPYG: | 129010291(ALDH1L2) 129032831(ALDH1L1) |
NLE: | 100587670(ALDH1L1) 100604236(ALDH1L2) |
HMH: | 116466824(ALDH1L1) 116478012(ALDH1L2) |
SSYN: | 129459340(ALDH1L2) 129471028(ALDH1L1) |
MCC: | 701242(ALDH1L2) 716977(ALDH1L1) |
MCF: | 102115759(ALDH1L2) 102146254(ALDH1L1) |
MTHB: | 126930896 126949102 |
MNI: | 105470240(ALDH1L1) 105497706(ALDH1L2) |
CSAB: | 103228129(ALDH1L1) 103239007(ALDH1L2) |
CATY: | 105573273(ALDH1L2) 105589811(ALDH1L1) |
PANU: | 101021537(ALDH1L2) 101025922(ALDH1L1) |
TGE: | 112619430(ALDH1L1) 112635275(ALDH1L2) |
MLEU: | 105533167(ALDH1L1) 105536219(ALDH1L2) |
RRO: | 104657483(ALDH1L2) 104675907(ALDH1L1) |
RBB: | 108528191(ALDH1L1) 108544280(ALDH1L2) |
TFN: | 117083372(ALDH1L1) 117089496(ALDH1L2) |
PTEH: | 111540530(ALDH1L2) 111544651(ALDH1L1) |
CANG: | 105508179(ALDH1L2) 105517974(ALDH1L1) |
CJC: | 100391281(ALDH1L1) 100403455(ALDH1L2) |
SBQ: | 101028391(ALDH1L2) 101052460(ALDH1L1) |
CIMI: | 108294203(ALDH1L1) 108312602(ALDH1L2) |
ANAN: | 105728684(ALDH1L2) 105733401(ALDH1L1) |
CSYR: | 103273966(ALDH1L2) 103276884(ALDH1L1) |
MMUR: | 105862258 105875597(ALDH1L2) |
LCAT: | 123625638(ALDH1L1) 123639352(ALDH1L2) |
PCOQ: | 105810661(ALDH1L2) 105821632(ALDH1L1) |
OGA: | 100946787(ALDH1L2) 100948849(ALDH1L1) |
MMU: | 107747(Aldh1l1) 216188(Aldh1l2) |
MCAL: | 110295709(Aldh1l1) 110303271(Aldh1l2) |
MPAH: | 110315010(Aldh1l1) 110326326(Aldh1l2) |
RNO: | 299699(Aldh1l2) 64392(Aldh1l1) |
MCOC: | 116076480(Aldh1l2) 116099258(Aldh1l1) |
ANU: | 117696791(Aldh1l2) 117715439(Aldh1l1) |
MUN: | 110549855(Aldh1l1) 110550767(Aldh1l2) |
CGE: | 100762089(Aldh1l1) 100772371(Aldh1l2) |
MAUA: | 101827187(Aldh1l2) 101840178(Aldh1l1) |
PROB: | 127235965(Aldh1l1) 127237833(Aldh1l2) |
PLEU: | 114681208(Aldh1l1) 114702991(Aldh1l2) |
MORG: | 121440478(Aldh1l1) 121462323 |
MFOT: | 126503812 126512444 |
AAMP: | 119803534(Aldh1l2) 119806339(Aldh1l1) |
NGI: | 103730367(Aldh1l1) 103742132(Aldh1l2) |
HGL: | 101697075(Aldh1l2) 101709289(Aldh1l1) |
CPOC: | 100717976(Aldh1l2) 100730205(Aldh1l1) |
CCAN: | 109681401(Aldh1l1) 109685514(Aldh1l2) |
DORD: | 105981372(Aldh1l1) 105988073(Aldh1l2) |
DSP: | 122107953(Aldh1l1) 122119300(Aldh1l2) |
PLOP: | 125358850(Aldh1l1) 125359187(Aldh1l2) |
NCAR: | 124970944 124983834 |
MMMA: | 107139676(Aldh1l2) 107150165(Aldh1l1) |
OPI: | 101523021(ALDH1L1) 101523052(ALDH1L2) |
TUP: | 102499911(ALDH1L1) 102502729(ALDH1L2) |
GVR: | 103587655(ALDH1L2) 103610886 |
CFA: | 474534(ALDH1L2) 476506(ALDH1L1) |
CLUD: | 112660210(ALDH1L1) 112669262(ALDH1L2) |
VVP: | 112914495(ALDH1L1) 112929137(ALDH1L2) |
VLG: | 121492117(ALDH1L2) 121494574(ALDH1L1) |
NPO: | 129511934(ALDH1L2) 129522071(ALDH1L1) |
AML: | 100465263(ALDH1L1) 100476798(ALDH1L2) |
UMR: | 103669466(ALDH1L1) 103676565(ALDH1L2) |
UAH: | 113255960(ALDH1L2) 113257287(ALDH1L1) |
UAR: | 123780833(ALDH1L2) 123802050(ALDH1L1) |
MPUF: | 101670776(ALDH1L2) 101683491(ALDH1L1) |
MNP: | 132010447(ALDH1L1) 132019298(ALDH1L2) |
MLK: | 131824324(ALDH1L1) 131839363(ALDH1L2) |
NVS: | 122891077(ALDH1L2) 122909123(ALDH1L1) |
ORO: | 101369691(ALDH1L1) 101380649(ALDH1L2) |
EJU: | 114207725(ALDH1L1) 114222944(ALDH1L2) |
ZCA: | 113917843(ALDH1L1) 113922912(ALDH1L2) |
MLX: | 117998787(ALDH1L2) 118005896(ALDH1L1) |
NSU: | 110578186(ALDH1L2) 110585005(ALDH1L1) |
LWW: | 102746407 102749777(ALDH1L2) |
FCA: | 101088592(ALDH1L2) 101091432(ALDH1L1) |
PYU: | 121022275(ALDH1L1) 121040494(ALDH1L2) |
PCOO: | 112858107(ALDH1L1) 112863325(ALDH1L2) |
PBG: | 122472631(ALDH1L2) 122487613(ALDH1L1) |
PVIV: | 125160650(ALDH1L1) 125170241(ALDH1L2) |
LRUF: | 124501713 124524168 |
PTG: | 102969433(ALDH1L2) 102971961(ALDH1L1) |
PPAD: | 109261178(ALDH1L1) 109265446(ALDH1L2) |
AJU: | 106968242 106971881 106985431 |
HHV: | 120221253(ALDH1L1) 120245710(ALDH1L2) |
BTA: | 505677(ALDH1L1) 516864(ALDH1L2) |
BIU: | 109556620(ALDH1L1) 109559467(ALDH1L2) |
BBUB: | 102408419(ALDH1L1) 102416005(ALDH1L2) |
BBIS: | 104988946(ALDH1L1) 104998300(ALDH1L2) |
CHX: | 102179144(ALDH1L1) 102189931(ALDH1L2) |
OAS: | 100913154(ALDH1L1) 101114182(ALDH1L2) |
BTAX: | 128048190(ALDH1L2) 128048938(ALDH1L1) |
ODA: | 120858635(ALDH1L2) 120868039(ALDH1L1) |
CCAD: | 122423681(ALDH1L2) 122424683(ALDH1L1) |
MBEZ: | 129536767(ALDH1L2) 129547665(ALDH1L1) |
SSC: | 100151976(ALDH1L2) 100622210(ALDH1L1) |
CFR: | 102512961(ALDH1L1) 102521632(ALDH1L2) |
CBAI: | 105071688(ALDH1L1) 105081391(ALDH1L2) |
CDK: | 105102962(ALDH1L2) 105104512(ALDH1L1) |
VPC: | 102534100(ALDH1L1) 102543803(ALDH1L2) |
BACU: | 103005570(ALDH1L2) 103015395(ALDH1L1) |
BMUS: | 118901863(ALDH1L2) 118903706(ALDH1L1) |
LVE: | 103079904(ALDH1L2) 103083157(ALDH1L1) |
OOR: | 101286106(ALDH1L2) 101287203(ALDH1L1) |
DLE: | 111168786(ALDH1L1) 111187792(ALDH1L2) |
PCAD: | 102974464(ALDH1L1) 102980582(ALDH1L2) |
PSIU: | 116761354(ALDH1L2) 116762583(ALDH1L1) |
NASI: | 112391007(ALDH1L2) 112411981(ALDH1L1) |
ECB: | 100053705(ALDH1L2) 100061108(ALDH1L1) |
EPZ: | 103552696(ALDH1L2) 103567591 |
EAI: | 106834458(ALDH1L1) 106846797(ALDH1L2) |
MYB: | 102246127(ALDH1L1) 102256559(ALDH1L2) |
MYD: | 102751421(ALDH1L1) 102763705(ALDH1L2) |
MMYO: | 118651256(ALDH1L2) 118663424(ALDH1L1) |
MLF: | 102433777(ALDH1L2) 102435890(ALDH1L1) |
MDT: | 132227083(ALDH1L2) 132239816(ALDH1L1) |
PKL: | 118708220(ALDH1L1) 118730514(ALDH1L2) |
EFUS: | 103289101(ALDH1L2) 103302459(ALDH1L1) |
MNA: | 107525201(ALDH1L1) 107545107(ALDH1L2) |
DRO: | 112321822(ALDH1L2) 112322753(ALDH1L1) |
PDIC: | 114506345(ALDH1L1) 114514058(ALDH1L2) |
PHAS: | 123810697(ALDH1L2) 123825970(ALDH1L1) |
MMF: | 118618641(ALDH1L1) 118623650(ALDH1L2) |
PPAM: | 129071264(ALDH1L2) 129081640(ALDH1L1) |
HAI: | 109377662(ALDH1L1) 109387752(ALDH1L2) |
RFQ: | 117028624(ALDH1L2) 117038749(ALDH1L1) |
PALE: | 102886245(ALDH1L2) 102893157(ALDH1L1) |
PGIG: | 120586980(ALDH1L1) 120614929(ALDH1L2) |
PVP: | 105302834(ALDH1L1) 105310852(ALDH1L2) |
RAY: | 107501175(ALDH1L2) 107518670(ALDH1L1) |
TOD: | 119247349(ALDH1L2) 119256429(ALDH1L1) |
SARA: | 101540284(ALDH1L1) 101545100(ALDH1L2) |
SETR: | 125998226(ALDH1L1) 126022318(ALDH1L2) |
LAV: | 100667848(ALDH1L2) 100671746(ALDH1L1) |
ETF: | 101643804(ALDH1L1) 101647708(ALDH1L2) |
DNM: | 101411027(ALDH1L1) 101429958(ALDH1L2) |
MDO: | 100022528(ALDH1L2) 100026594(ALDH1L1) |
GAS: | 123247283(ALDH1L1) 123250103(ALDH1L2) |
SHR: | 100918967(ALDH1L1) 100922488(ALDH1L2) |
PCW: | 110204922(ALDH1L1) 110205675(ALDH1L2) |
TVP: | 118831011(ALDH1L1) 118851359(ALDH1L2) |
OAA: | 100074128(ALDH1L2) 100078554(ALDH1L1) |
XLA: | 108711033(aldh1l2.L) 108713198(aldh1l2.S) 444321(aldh1l1.L) |
XTR: | 100127737(aldh1l2) 496436(aldh1l1) |
NPR: | 108784934(ALDH1L2) 108795920 |
RTEM: | 120932117(ALDH1L2) 120945119 |
BBUF: | 120978592(ALDH1L1) 120979352(ALDH1L2) |
BGAR: | 122923157 122928092(ALDH1L2) 122943341(ALDH1L1) |
MUO: | 115471840(ALDH1L1) 115477711(ALDH1L2) |
GSH: | 117351320(ALDH1L1) 117363313(ALDH1L2) |
DRE: | 100333269(aldh1l2) 100526683(aldh1l1) |
SRX: | 107710173 107726046(aldh1l2) 107743541 107755669 |
SANH: | 107656123 107656317 107658818 107691487 |
SGH: | 107580561 107586352 107592231 |
CAUA: | 113048288 113050708 113059007 |
CGIB: | 127956461 127976967 128015480 |
PTET: | 122343323(aldh1l2) 122346799(aldh1l1) |
LROH: | 127163935(aldh1l2) 127167007(aldh1l1) |
OMC: | 131538680(aldh1l2) 131543094(aldh1l1) |
PPRM: | 120466934(aldh1l1) 120476576(aldh1l2) |
MAMB: | 125245544(aldh1l2) 125278104(aldh1l1) |
CIDE: | 127510552 127514560 |
CERY: | 137010616(aldh1l1) 137024242(aldh1l2) |
MASI: | 127435253 127436391 |
IPU: | 108272091(aldh1l1) 108280121 |
IFU: | 128614746(aldh1l1) 128623462(aldh1l2) |
PHYP: | 113530536 113532247(aldh1l2) |
SMEO: | 124390046(aldh1l1) 124401507(aldh1l2) |
TFD: | 113642874(aldh1l1) 113645752(aldh1l2) |
TVC: | 132844518(aldh1l1) 132858690(aldh1l2) |
TRN: | 134316872(aldh1l1) 134323809(aldh1l2) |
AMEX: | 103022276(aldh1l1) 103024881(aldh1l2) |
CMAO: | 118808393(aldh1l1) 118812560(aldh1l2) |
EEE: | 113581548 113584409(aldh1l2) |
CHAR: | 105896739(aldh1l2) 105901876(aldh1l1) |
TRU: | 101063025 101078185(aldh1l2) |
TFS: | 130519515(aldh1l2) 130524463 |
TNG: | GSTEN00003776G001 GSTEN00032475G001 |
LCO: | 104923764(aldh1l2) 104936356 |
TBEN: | 117475656 117483189(aldh1l2) |
CGOB: | 115008648 115028413 |
PGEO: | 117439154(aldh1l2) 117446862(aldh1l1) |
EMAC: | 134879444(aldh1l2) 134882555 |
ELY: | 117249218(aldh1l2) 117257498(aldh1l1) |
EFO: | 125882983(aldh1l2) 125885409(aldh1l1) |
PLEP: | 121951872(aldh1l1) 121961501(aldh1l2) |
SLUC: | 116042053(aldh1l2) 116050232 |
ECRA: | 117939092(aldh1l2) 117943786(aldh1l1) |
PFLV: | 114549841 114553837 |
GAT: | 120818154(aldh1l2) 120835586(aldh1l1) |
PPUG: | 119211597(aldh1l2) 119229951(aldh1l1) |
AFB: | 129105414(aldh1l1) 129112255(aldh1l2) |
CLUM: | 117726218(aldh1l2) 117730634(aldh1l1) |
PSWI: | 130200473(aldh1l2) 130208290(aldh1l1) |
MSAM: | 119885546 119918162(aldh1l2) |
SCHU: | 122862279 122871409(aldh1l2) |
CUD: | 121505314(aldh1l2) 121506812(aldh1l1) |
ALAT: | 119020955(aldh1l1) 119032742(aldh1l2) |
MZE: | 101480024 101485420 112433931 |
ONL: | 100704523 100710779(aldh1l2) |
OAU: | 116313687(aldh1l1) 116316283(aldh1l2) |
OLA: | 101167504(aldh1l2) 101174660 |
OML: | 112145476(aldh1l1) 112157195(aldh1l2) |
CSAI: | 133424331(aldh1l2) 133448957(aldh1l1) |
XMA: | 102232560(aldh1l2) 102235454 102237507 111605848 |
XCO: | 114135580 114160830(aldh1l2) |
XHE: | 116709908 116736641(aldh1l2) |
PRET: | 103459710 103465496 |
PFOR: | 103151786(aldh1l2) 103152725 |
PLAI: | 106959693 106960202(aldh1l2) |
PMEI: | 106926622(aldh1l2) 106929322 |
GAF: | 122826500(aldh1l2) 122833744(aldh1l1) |
PPRL: | 129354809(aldh1l1) 129376022(aldh1l2) |
CTUL: | 119772607 119775063(aldh1l2) |
GMU: | 124857202(aldh1l1) 124883334(aldh1l2) |
KMR: | 108228235 108228428(aldh1l2) |
ALIM: | 106526877 106530822(aldh1l2) |
AOCE: | 111580328 111589053(aldh1l2) |
MCEP: | 124999922(aldh1l2) 125007079(aldh1l1) |
CSEM: | 103382426(aldh1l2) 103386628 |
POV: | 109629008 109637471(aldh1l2) |
SSEN: | 122760542 122766131(aldh1l2) |
HHIP: | 117757373(aldh1l2) 117760918(aldh1l1) |
HSP: | 118101263(aldh1l2) 118103826(aldh1l1) |
PPLT: | 128428678(aldh1l2) 128447127(aldh1l1) |
SMAU: | 118309406(aldh1l1) 118319163(aldh1l2) |
SDU: | 111221548 111224720(aldh1l2) |
SLAL: | 111664233(aldh1l2) 111668621 |
XGL: | 120800781(aldh1l2) 120807326(aldh1l1) |
SBIA: | 133493198 133507181(aldh1l1) |
PEE: | 133398182 133408953(aldh1l1) |
PTAO: | 133473676 133483122(aldh1l1) |
BPEC: | 110167873 110170281 |
MALB: | 109960958(aldh1l2) 109970592 |
BSPL: | 114855513(aldh1l1) 114863299(aldh1l2) |
SJO: | 128354915(aldh1l1) 128385240(aldh1l2) |
SASA: | 106576152 106583638 106609325 |
STRU: | 115150147 115180207 115198784 |
OTW: | 112214304 112246202 112256543(aldh1l2) |
OMY: | 110490304(aldh1l2) 110500181 110528507 |
OGO: | 123994601 124014283 124026926 |
ONE: | 115106988 115133131 115143729 |
OKI: | 109864290 109891397 109896735 |
OKE: | 118365951(aldh1l2) 118372202 118399709 |
SALP: | 111970466 112072655 |
SNH: | 120032248 120050022 120065415 |
CCLU: | 121543627 121575698 121578012 |
ELS: | 105024789 105030469(aldh1l2) |
SFM: | 108918573 108921000(aldh1l2) |
PKI: | 111844275(aldh1l2) 111851698 |
AANG: | 118210495(aldh1l1) 118218844(aldh1l2) |
LOC: | 102683454(aldh1l2) 102687756 |
PSPA: | 121298085 121318469 121319628 |
ARUT: | 117411986 117413641 117415484 117419439 |
PSEX: | 120534321(aldh1l2) 120540392(aldh1l1) |
LCM: | 102358231(ALDH1L1) 102358739(ALDH1L2) |
CMK: | 103176681(aldh1l1) 103189341(aldh1l2) |
RTP: | 109921813(aldh1l2) 109925323 |
CPLA: | 122559232 122561527 |
HOC: | 132822211(aldh1l1) 132826817 |
LERI: | 129704648(aldh1l1) 129707620 |
PMRN: | 116942317(ALDH1L2) 116952313 |
LRJ: | 133349522 133349574 133355424 |
DSI: | Dsimw501_GD24321(Dsim_GD24321) |
AMER: | 121596773 121602234 |
AALB: | 109409300 109419523 115258594 |
PPOI: | 119107143 119108687 |
LPOL: | 106468095 106469348 |
CBR: | CBG_05984(Cbr-alh-3) |
MAEA: | 128217563 128217973 |
LLON: | 135490706 135491681 |
» show all
|
Reference |
|
Authors |
Kutzbach C, Stokstad EL. |
Title |
Partial purification of a 10-formyl-tetrahydrofolate: NADP oxidoreductase from mammalian liver. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 1.5.1.6 |
ExPASy - ENZYME nomenclature database: | 1.5.1.6 |
BRENDA, the Enzyme Database: | 1.5.1.6 |
|