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Entry
EC 1.5.3.10                 Enzyme                                 

Name
dimethylglycine oxidase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
N,N-dimethylglycine:oxygen oxidoreductase (demethylating)
Reaction(IUBMB)
N,N-dimethylglycine + H2O + O2 = sarcosine + formaldehyde + H2O2 [RN:R01564]
Reaction(KEGG)
Substrate
N,N-dimethylglycine [CPD:C01026];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
sarcosine [CPD:C00213];
formaldehyde [CPD:C00067];
H2O2 [CPD:C00027]
Comment
A flavoprotein (FAD). Does not oxidize sarcosine.
History
EC 1.5.3.10 created 1992
Pathway
ec00260  Glycine, serine and threonine metabolism
Orthology
K00309  dimethylglycine oxidase
Genes
MGR: MGG_12421
TMN: UCRPA7_1978
FGR: FGSG_03414
FPU: FPSE_08388
FVR: FVEG_10784
FOX: FOXG_12340
NHE: NECHADRAFT_51705
MAW: MAC_06835
MAJ: MAA_00906
CMT: CCM_08027
ANI: AN8654.2
ANG: ANI_1_1304134(An15g02590)
PTE: PTT_07671
PLEO: OHA_1_00894(mlr_2)
BMQ: BMQ_1539
BMD: BMD_1520
BMEG: BG04_3831(dmg)
MMC: Mmcs_2459
MKM: Mkms_2504
MJL: Mjls_2496
MMI: MMAR_4420(gcvT_2)
MMAE: MMARE11_42450(gcvT_2)
MLI: MULP_04640(gcvT_2)
MGI: Mflv_3080
MVQ: MYVA_3366
CVA: CVAR_2042
CTER: A606_08170
ROP: ROP_14920
RHB: NY08_3778
RFA: A3L23_02135(dmg_1)
RHS: A3Q41_01248(dmg)
GOR: KTR9_1190
GOM: D7316_03170(dmg)
SRT: Srot_2474
SCB: SCAB_6961
SBH: SBI_00369
SHY: SHJG_2829
SALS: SLNWT_1480
SALU: DC74_1378
SALL: SAZ_07405
STRE: GZL_07820
SLD: T261_7397
SRW: TUE45_01810(mlr_1)
SMAL: SMALA_0689
SFK: KY5_1140
ART: Arth_3718
AAU: AAur_0484
SERJ: SGUI_2359
STRR: EKD16_17065(mlr2)
SRO: Sros_3855
GOB: Gobs_2879
MMAR: MODMU_2885
AMD: AMED_7548
AOI: AORI_6809
PSEA: WY02_22370
PSEE: FRP1_20290
KAL: KALB_3171
ACTI: UA75_06595
ACAD: UA74_06595
AHG: AHOG_06315(mlr)
ACTN: L083_4087
AFS: AFR_18435
SNA: Snas_1822
RXY: Rxyl_0762
HALH: HTSR_1750
HHSR: HSR6_1816
HMA: pNG7366(gcvT3) pNG7370(gcvT1)
HHI: HAH_5182(gcvT3) HAH_5196(gcvT4) HAH_5197(gcvT5)
HWA: HQ_1760A(dmg1) HQ_1761A(dmg2)
HWC: Hqrw_1889(dmg1) Hqrw_1891(dmg2)
HVO: HVO_B0014(dmg1)
 » show all
Taxonomy
Reference
1
  Authors
Mori, N., Kawakami, B., Tani, Y. and Yamada, H.
  Title
Purification and properties of dimethylglycine oxidase from Cylindrocarpon didymum M-1.
  Journal
Agric Biol Chem 44:1383-1389 (1980)
Other DBs
ExplorEnz - The Enzyme Database: 1.5.3.10
IUBMB Enzyme Nomenclature: 1.5.3.10
ExPASy - ENZYME nomenclature database: 1.5.3.10
BRENDA, the Enzyme Database: 1.5.3.10
CAS: 37256-30-7

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