KEGG   ENZYME: 1.6.1.3Help
Entry
EC 1.6.1.3                  Enzyme                                 

Name
NAD(P)+ transhydrogenase;
pyridine nucleotide transhydrogenase;
transhydrogenase (ambiguous);
nicotinamide adenine dinucleotide (phosphate) transhydrogenase (ambiguous);
NAD+ transhydrogenase (ambiguous);
NADH transhydrogenase (misleading);
nicotinamide nucleotide transhydrogenase (ambiguous);
NADPH-NAD+ transhydrogenase (ambiguous);
pyridine nucleotide transferase (ambiguous);
NADPH-NAD+ oxidoreductase (ambiguous);
NADH-NADP+-transhydrogenase (ambiguous);
NADPH:NAD+ transhydrogenase;
H+-Thase (ambiguous);
non-energy-linked transhydrogenase (ambiguous)
Class
Oxidoreductases;
Acting on NADH or NADPH;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
NADPH:NAD+ oxidoreductase
Reaction(IUBMB)
NADPH + NAD+ = NADP+ + NADH [RN:R00112]
Reaction(KEGG)
Substrate
NADPH [CPD:C00005];
NAD+ [CPD:C00003]
Product
NADP+ [CPD:C00006];
NADH [CPD:C00004]
Comment
The enzyme catalyses the NADPH-driven reduction of NAD+. This entry stands for enzymes whose stereo-specificity with respect to NADPH is not known. [cf. EC 1.6.1.1, NAD(P)+ transhydrogenase (Si-specific) and EC 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)].
History
EC 1.6.1.3 created 2013
Reference
1  [PMID:13752224]
  Authors
KEISTER DL, SAN PIETRO A, STOLZENBACH FE
  Title
Pyridine nucleotide transhydrogenase from spinach. I. Purification and properties.
  Journal
J Biol Chem 235:2989-96 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 1.6.1.3
IUBMB Enzyme Nomenclature: 1.6.1.3
ExPASy - ENZYME nomenclature database: 1.6.1.3
BRENDA, the Enzyme Database: 1.6.1.3

  All links  
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
All databases (10)   

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