KEGG   ENZYME: 1.7.1.2Help
Entry
EC 1.7.1.2                  Enzyme                                 

Name
nitrate reductase [NAD(P)H];
assimilatory nitrate reductase ( ambiguous);
assimilatory NAD(P)H-nitrate reductase;
NAD(P)H bispecific nitrate reductase;
nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate));
nitrate reductase NAD(P)H;
NAD(P)H-nitrate reductase;
nitrate reductase [NAD(P)H2];
NAD(P)H2:nitrate oxidoreductase
Class
Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
nitrite:NAD(P)+ oxidoreductase
Reaction(IUBMB)
nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ [RN:R00794 R00796]
Reaction(KEGG)
Substrate
nitrite [CPD:C00088];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
nitrate [CPD:C00244];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
An iron-sulfur molybdenum flavoprotein.
History
EC 1.7.1.2 created 1961 as EC 1.6.6.2, transferred 2002 to EC 1.7.1.2
Pathway
ec00910  Nitrogen metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K10534  nitrate reductase (NAD(P)H)
Genes
ATH: AT1G37130(NIA2) AT1G77760(NIA1)
GMX: 100813471 100818103 100818642 732634(INR2)
MTR: MTR_3g073150 MTR_3g073180 MTR_5g059820
FVE: 101295234
CSV: 101219000(NR2) 101219242(NR3)
POP: 7469126
VVI: 100264320
SLY: 100736473(NR)
OSA: 4330867 4345795 4345798
DOSA: Os02t0770800-01(Os02g0770800) Os08t0468100-01(Os08g0468100) Os08t0468700-00(Os08g0468700)
ZMA: 100383210
CRE: CHLREDRAFT_184661(NIT1)
VCN: VOLCADRAFT_76569(nitA)
NCR: NCU05298(nit-3)
MGR: MGG_06062
BFU: BCIN_07g01270(BcniaD)
ANG: ANI_1_2088064(An07g08910) ANI_1_2090064(An07g08920) ANI_1_802074(An08g05610)
ABE: ARB_06695
TVE: TRV_04039
PTE: PTT_08192
 » show all
Taxonomy
Reference
1
  Authors
Nason, A.
  Title
Nitrate reductases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 587-607.
Reference
2  [PMID:5864033]
  Authors
Paneque A, Del Campo FF, Ramirez JM, Losada M.
  Title
Flavin nucleotide nitrate reductase from spinach.
  Journal
Biochim Biophys Acta 109:79-85 (1965)
Reference
3  [PMID:11289301]
  Authors
Campbell WH.
  Title
Structure and function of eukaryotic NAD(P)H:nitrate reductase.
  Journal
Cell Mol Life Sci 58:194-204 (2001)
DOI:10.1007/PL00000847
Reference
4  [PMID:8534676]
  Authors
Berks BC, Ferguson SJ, Moir JW, Richardson DJ.
  Title
Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions.
  Journal
Biochim Biophys Acta 1232:97-173 (1995)
DOI:10.1016/0005-2728(95)00092-5
Other DBs
ExplorEnz - The Enzyme Database: 1.7.1.2
IUBMB Enzyme Nomenclature: 1.7.1.2
ExPASy - ENZYME nomenclature database: 1.7.1.2
BRENDA, the Enzyme Database: 1.7.1.2
CAS: 9029-27-0

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