KEGG ENZYME: 1.7.7.1

ENZYME: 1.7.7.1

Entry

EC 1.7.7.1 Enzyme

Name

ferredoxin---nitrite reductase

Class

Oxidoreductases;
Acting on other nitrogenous compounds as donors;
With an iron-sulfur protein as acceptor

Sysname

ammonia:ferredoxin oxidoreductase

Reaction(IUBMB)

NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+ [RN:R00790]

Reaction(KEGG)

R00790

Substrate

NH3 [CPD:C00014];
H2O [CPD:C00001];
oxidized ferredoxin [CPD:C00139]

Product

nitrite [CPD:C00088];
reduced ferredoxin [CPD:C00138];
H+ [CPD:C00080]

Comment

An iron protein. Contains siroheme and [4Fe-4S] clusters.

History

EC 1.7.7.1 created 1972, modified 1999

Pathway

ec00910

Nitrogen metabolism

ec01120

Microbial metabolism in diverse environments

Orthology

K00366

ferredoxin-nitrite reductase

Genes

ATH:	AT2G15620(NIR1)

ALY:

9319973

CRB:

17892492

CSAT:

104747379 104766730 104792805

EUS:	EUTSA_v10022613mg

BRP:	103844354 103848008

BNA:	106361629 106410460 106445633 106446818

BOE:	106306537 106318938

RSZ:	108812867 108823413 108832401

THJ:	104807271 104819578

CPAP:

110813767

CIT:

102616714

CIC:	CICLE_v10028067mg

TCC:

GRA:

GHI:

GAB:

DZI:	111283096 111308936

EGR:

104418735

GMX:	100775519 732631(NIR)

GSJ:	114388555 114419692

PVU:	PHAVU_003G292100g

VRA:

VAR:

VUN:

CCAJ:

MTR:	MTR_4g086020

CAM:

101501715

LJA:	Lj4g3v0588830.1(Lj4g3v0588830.1) Lj4g3v0588840.1(Lj4g3v0588840.1) Lj4g3v0588840.2(Lj4g3v0588840.2)

ADU:

AIP:

LANG:

FVE:

RCN:

PPER:

PMUM:

PAVI:

MDM:

PXB:

ZJU:

CSV:	101217505(NIR)

CMO:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

JRE:

QSU:

VVI:

SLY:	778325(nii1) 778326

SPEN:

107003008 107032698

SOT:	102581851(NIR) 102596437

CANN:

107840295(nii1) 107858928

NTA:	107764462 107765655(nii4) 107767028(nii2) 107798816(nir-1)

NSY:	104226228 104232141 104237541

NTO:	104118806 104118966

NAU:	109206944 109235478

INI:	109161365 109162137

SIND:

105169542

OEU:

111411582

HAN:	110878688 110938246

LSV:

CCAV:

DCR:

BVG:

SOE:

CQI:	110693275 110720167

NNU:

104601782

PSOM:

113346649 113356842

OSA:	4326014 4330835

DOSA:

Os01t0357100-01(Os01g0357100)

OBR:

BDI:

ATS:

SBI:

ZMA:	103627781 542264

SITA:

PDA:

EGU:

MUS:

DCT:

PEQ:

AOF:

ATR:

SMO:	SELMODRAFT_178021 SELMODRAFT_183174

PPP:	112278473 112293556

CRE:	CHLREDRAFT_192085(NII1)

VCN:	VOLCADRAFT_83067

MNG:	MNEG_12515

CSL:	COCSUDRAFT_29833

CVR:	CHLNCDRAFT_26644

OLU:	OSTLU_50765

OTA:	OT_ostta10g00930

BPG:	Bathy02g01510

MIS:	MICPUN_113259(nii)

MPP:	MICPUCDRAFT_70828(NII)

CCP:	CHC_T00003048001

PTI:	PHATRDRAFT_27757

FCY:	FRACYDRAFT_185143 FRACYDRAFT_263086

TPS:	THAPSDRAFT_262125(NIR_2)

NGD:	NGA_0226700(NIRA)

EHX:	EMIHUDRAFT_428968 EMIHUDRAFT_430293(NII1)

GTT:	GUITHDRAFT_81582

SPIU:

SPICUR_05360

SROS:

BBH56_04690

URU:	DSM104443_00917(sir_1)

BEBA:

BWI17_00025(nirA)

TDN:	Suden_1241

SUA:	Saut_0049 Saut_0726

SULN:

FJR47_03250 FJR47_05710

SULG:

FJR48_02940 FJR48_08170

SULC:

CVO_03760 CVO_06380

SPAL:

FM071_00255 FM071_03045

SKU:	Sulku_1384

SULR:

B649_06150 B649_07115

ALK:	ALEK_3087 ALEK_3165(nirA)

ALP:	LPB137_12740

PACO:

AACT_0422

HYO:	NNO_0571 NNO_0690 NNO_1994

NSA:	Nitsa_1615

SUN:	SUN_0312 SUN_1492

SLH:	YH65_04275 YH65_09495

NIS:	NIS_0952 NIS_1436

CMED:

FE773_05370

DEU:

DBW_0155

BJA:	bll4571(bll4571)

BJU:	BJ6T_51120

BJP:	RN69_24920(nirA)

BRA:

BBT:

BRS:

AOL:

BRC:	BCCGELA001_19590(nirA)

BRAD:

BF49_6922

BIC:	LMTR13_19975(nirA)

BRO:	BRAD285_3579

BOT:	CIT37_31020(nirA)

BRQ:	CIT40_15615(nirA)

BGQ:	X265_19675(nirA)

BGZ:	XH91_17745(nirA)

BSYM:

CIT39_14765(nirA)

BBET:

F8237_32465

BARH:

WN72_26030(nirA)

BVZ:	BRAD3257_4443

RPA:	RPA3710(nirA)

RPB:

RPB_1754

RPE:

RPE_1260

RPT:

Rpal_4231

RPX:	Rpdx1_1640

BOP:	AXW83_02210(nirA)

BOS:	BSY19_1008(cobG)

BVV:	BHK69_13085(nirA)

BOI:	BLM15_08630(nirA)

BOF:	FQV39_24785

VGO:	GJW-30_1_00020(sir)

TRB:	HB776_07390

XAU:

AZC:

SNO:

STAR:

LNE:	FZC33_21260

MEA:	Mex_1p4940

MDI:

MEX:

MCH:

MPO:

MZA:	B2G69_04440(nirA)

MRD:	Mrad2831_2299

MET:

M446_3747

MNO:

Mnod_2867

MOR:	MOC_2721(cobG)

META:

Y590_22905(nirA)

MAQU:

Maq22A_c03270(cysI)

MPHY:

MCBMB27_01914

MEE:	DA075_25670(nirA)

METD:

C0214_24745(nirA)

METX:

A3862_19285(nirA)

METS:

DK389_29715(nirA)

METI:

DK427_15885(nirA)

MMES:

MMSR116_20195

MTEA:

DK419_19205(nirA)

MSL:

Msil_1785

BBAR:

RHAL1_02515

HNI:	W911_01355(nirA)

FIL:	BN1229_v1_1477

FIY:	BN1229_v1_1478

MCG:

MSC:

MROS:

MPAR:

PSIN:

CAK95_17010(nirA)

RGI:	RGI145_04695(nirA)

ROS:	CTJ15_12700(nirA)

RMUC:

FOB66_06500

PHR:	C6569_07430(nirA)

PSTG:

BAN:

BAR:

BAT:

BAH:	BAMEG_3149

BAI:

BAA_1513

BAX:	H9401_1357

BANT:

BANR:

BANS:

BANH:

BANV:

BCE:

BCA:	BCE_1547(nirA)

BCZ:	BCE33L1307(nirA)

BCR:	BCAH187_A1585

BCB:	BCB4264_A1479

BCU:	BCAH820_1515

BCG:	BCG9842_B3865

BCQ:	BCQ_1497(nirA)

BCX:

BCA_1481

BAL:	BACI_c14650(nirA)

BNC:

BCF:

BCER:

BCEF:

BCY:	Bcer98_1146

BTK:	BT9727_1306(nirA)

BTL:

BALH_1279

BTB:	BMB171_C1261

BTT:

HD73_1654

BTHR:

YBT1520_08215

BTHI:

BTK_08415

BTC:	CT43_CH1353

BTF:	YBT020_07770

BTM:

MC28_0661

BTG:	BTB_c14660(nirA)

BTI:

BTG_13620

BTN:	BTF1_04825

BTHT:

BTHU:

BTW:

BTHY:

BWE:	BcerKBAB4_1347

BWW:	bwei_3573(nirA)

BMYO:

BG05_4467

BTY:	Btoyo_4065

BMYC:

DJ92_4074

BBY:	CY96_06290

BWD:	CT694_07930

BTRO:

FJR70_29775

BMOB:

MLA2C4_07525

BCO:	Bcell_3351

BACI:

B1NLA3E_07925

BIF:	N288_13270

BMET:

BMMGA3_02570

BSM:	BSM4216_1926

BHK:	B4U37_02475

BKW:	BkAM31D_06010(sir)

BKO:	CKF48_21930

GWC:	GWCH70_0410

GMC:	GY4MC1_3368

GTH:	Geoth_3459

PTL:	AOT13_05575

PTB:	DER53_06675

ANM:	GFC28_2129

ANL:	GFC29_3305

AND:	GRQ40_02550

ACAI:

ISX45_18075

FPN:	ABE65_010040

FAR:	ABE41_011380

APAK:

AP3564_16500

BSJ:	UP17_12950

BMUR:

ABE28_012075

PBUT:

DTO10_00290

AIA:	AWH56_020965(nirA) AWH56_024045

STEA:

C0679_12480

BLR:	BRLA_c010900

BFM:	BP422_17045

BAGR:

BA6348_09640

BRW:	GOP56_21420

PPY:

PPE_04345

PPM:	PPSC2_22735(nirA)

PPO:	PPM_4515(nirA)

PPOL:

X809_39225

PPQ:	PPSQR21_046040(cysI)

PPOY:

RE92_14480

PTA:	HPL003_04235

PLV:	ERIC2_c01410(nirA)

PSAB:

PSAB_21990

PDU:	PDUR_24960

PGM:	PGRAT_29705

PSTE:

PSTEL_24590

PRI:

PRIO_6210

PPEO:

ABE82_22880

POW:	IJ21_06980

PSWU:

SY83_11190

PKB:	B4V02_02540

PAIH:

ASL14_15075

PALB:

EJC50_01410

PCHI:

PC41400_02845

PBK:	Back11_31370 Back11_52920

PRZ:	GZH47_18625

PLYC:

GXP70_27920

ANX:	ACH33_15550

ASOC:

CB4_03918(sir)

TUM:	CBW65_22295

EFF:	skT53_34240

LFB:	C1X05_13335

TVU:	AB849_007515

KPUL:

GXN76_05270

KEB:	GXN75_06220

LCY:	LC20004_03850

CAC:

CA_C0094

CAE:	SMB_G0095(sir1)

CAY:

CPE:

CPF:

CPR:

CBK:

CBT:

CBE:	Cbei_0832 Cbei_3024

CBZ:	Cbs_0832 Cbs_3024

CBEI:

LF65_00913 LF65_03404

CLS:	CXIVA_11000

CSR:	Cspa_c47420

CPAS:

Clopa_4268

CPAT:

CLPA_c03220(sir1)

CPAE:

CPAST_c03220(sir1)

CSB:	CLSA_c10870(nirA1) CLSA_c23430(nirA2)

CBV:

U729_1400

CTYK:

CTK_C07770

CEU:	A7L45_02455

CSEP:

CP523_02260

CDY:	F3K33_04535 F3K33_15425

CCL:	Clocl_3420

CLE:	Clole_2524

CEW:	EKH84_15255

ACEL:

acsn021_34950

CDF:	CD630_24310

PDC:	CDIF630_02674

CDC:	CD196_2276

CDL:	CDR20291_2323

PDF:	CD630DERM_24310

PSOR:

RSJ16_11430

HCV:	FTV88_1457(nirA)

BPRS:

CK3_09570

MED:

MELS_2103

PUF:

UFO1_4436

AFN:	Acfer_1737

EBM:	SG0102_23740

ACIT:

HPK19_01485

ACE:

Acel_2055

RXY:

Rxyl_0963

RRD:	RradSPS_0874

BSOL:

FSW04_12215

SYN:	slr0898(nirA)

SYZ:	MYO_125100(nirA)

SYY:	SYNGTS_2485(nirA)

SYT:	SYNGTI_2484(nirA)

SYS:	SYNPCCN_2483(nirA)

SYQ:	SYNPCCP_2483(nirA)

SYJ:	D082_20400(nirA)

SYO:	C7I86_13015

SYC:	syc0310_d(nirA) syc2243_c

SYF:	Synpcc7942_1240 Synpcc7942_1851

SYW:	SYNW2477(nirA)

SYD:	Syncc9605_2656

SYE:	Syncc9902_2284

SYG:

sync_2898

SYR:	SynRCC307_2482(nirA)

SYX:	SynWH7803_2492(nirA)

SYP:	SYNPCC7002_A1827(nirA)

CYA:	CYA_0612(nirA)

CYB:	CYB_0034(nirA)

SYNE:

Syn6312_1098 Syn6312_2230

SYNP:

Syn7502_00096 Syn7502_02117

SYNK:

KR100_00620(nirA)

SYNR:

KR49_08700(nirA)

SYND:

KR52_02680(nirA)

SYU:	M744_07195 M744_10440(nirA)

SYH:	Syncc8109_2723

SYNW:

SynWH8103_02865(nirA)

SYV:	AWQ23_09310(nirA)

SYL:	AWQ21_09325

SYNC:

CB0101_07940

TEL:	tlr1349(nirA)

THN:	NK55_02220(nirA)

TVN:	NIES2134_111990(nirA)

THEC:

FFX45_09325

CGC:	Cyagr_2450

CYI:	CBM981_2472(nirA)

DSL:	Dacsa_3250

CMP:	Cha6605_4426 Cha6605_5140

LEP:	Lepto7376_2935

LEN:	LEP3755_01220 LEP3755_49220

LET:	O77CONTIG1_04175(sir_2)

LBO:	LBWT_24130 LBWT_53930

HHG:	XM38_031120

PSEU:

Pse7367_2346

PSER:

ABRG53_1414(cobG) ABRG53_1568(nirA)

PMT:

PMT_2239

PMN:	PMN2A_1298

PMF:	P9303_29861(nirA)

PME:	NATL1_21711(nirA)

PRC:	EW14_1289 EW14_1540

PRM:

EW15_2256

AMR:	AM1_2984(nirA)

THEU:

HPC62_18875

GLP:	Glo7428_1960

GEN:	GM3709_1801

GEE:	GM3708_1114 GM3708_2695

CHON:

NIES4102_02000

MAR:	MAE_02720(nirA) MAE_18410(nirA)

MPK:

VL20_4070

MIQ:	B5D77_21090(nirA) B5D77_22670

MVZ:	myaer102_37790 myaer102_51660(nirA)

CAN:	Cyan10605_0291

CSN:	Cyast_1533

CYL:	AA637_06910(nirA)

HAO:	PCC7418_0557

ENN:	FRE64_00315

CYT:	cce_1223(nirA)

CWA:	CwatDRAFT_3683

CYP:	PCC8801_2468

CYH:	Cyan8802_3641

CYC:	PCC7424_1683

CYJ:	Cyan7822_3569

CYN:	Cyan7425_4573

TER:

Tery_1068

MIC:	Mic7113_0127 Mic7113_0133

ARP:	NIES39_G00870 NIES39_H00190(nirA)

PAGH:

NIES204_04440 NIES204_38560(nirA)

OXY:	HCG48_17470

LFS:	HFV01_15580(cobG) HFV01_17980

GEI:	GEI7407_0749

OAC:	Oscil6304_5870 Oscil6304_5991

ONI:	Osc7112_2344 Osc7112_5690

MPRO:

BJP34_10800(nirA)

CEP:	Cri9333_3676

GVI:	gvip212(nirA)

GLJ:	GKIL_0321(nirA)

ANA:	alr0607(nirA)

NPU:	Npun_F6481 Npun_R1528

NOS:	Nos7107_2252

NOP:	Nos7524_1864 Nos7524_4343

NON:	NOS3756_02310(nirA) NOS3756_06400

NFL:	COO91_00301 COO91_05896

NOE:	CLI64_03620(cobG) CLI64_07165

NSH:	GXM_05954 GXM_06315

NED:	HUN01_28730(cobG) HUN01_33660

AVA:

Ava_4539

NAZ:

Aazo_0121

ANB:	ANA_C13777(nirA) ANA_C20545(cobG)

ACY:	Anacy_1493 Anacy_5141

AWA:	AA650_11745(nirA) AA650_11950

ANN:	EH233_13985

CSG:	Cylst_3297 Cylst_3622

CALO:

Cal7507_0648 Cal7507_2110

CALT:

Cal6303_1024 Cal6303_5351

CALH:

IJ00_18230(nirA) IJ00_25400

RIV:	Riv7116_0549

FIS:	FIS3754_01070 FIS3754_25710

DOU:	BMF77_03993(sir_2) BMF77_04146(sir_3)

DFS:	HGD76_17970 HGD76_18785(cobG)

CCUR:

IAR63_07915 IAR63_14240

TOQ:	HCG51_00950(cobG) HCG51_23345

NCN:	BZZ01_02235(nirA) BZZ01_28210

CTHE:

Chro_3568 Chro_5389

PLP:	Ple7327_1240

SCS:	Sta7437_1527

STAN:

STA3757_35790

HAU:	Haur_1746 Haur_2333

TBH:	Tbon_10135(nirA)

TTR:

Tter_1333

TTH:

TT_C0313

CCZ:	CCALI_00759

OTE:

Oter_1737

OBG:	Verru16b_03269(sir)

VBH:	CMV30_00410(nirA)

OBT:	OPIT5_22765

CAA:

Caka_0346

ROO:	G5S37_05315

LUO:	HHL09_23170

RBA:	RB379(nirA)

PSL:

Psta_4085

PIR:	VN12_22100(sir_2)

RUL:	UC8_50680(sir_2)

AHEL:

Q31a_61810(sir_2)

AAGG:

ETAA8_08120(sir_1)

PND:	Pla175_38590(sir_1)

PLM:

Plim_3055

PBS:	Plabr_3250

PLS:	VT03_13290(sir_2)

FMR:	Fuma_05799(sir_2)

MRI:	Mal4_12930(sir_2)

SDYN:

Mal52_33040(sir_2)

LRS:	PX52LOC_07455(nirA)

SACI:

Sinac_5751

PBOR:

BSF38_01030(sir_1)

PHM:	PSMK_20410

PCOR:

KS4_12750(sir)

HBS:	IPV69_25765

ACM:	AciX9_0128

GMA:	AciX8_0892

TRS:	Terro_1214

TALB:

FTW19_05135

EDA:	GWR55_03175

FMO:	C4N19_08735

IPO:	Ilyop_0920

LEO:	AMK43_04885

STR:	Sterm_0485

RMR:

Rmar_2774

RMG:	Rhom172_2354

HTH:

HTH_0443

HTE:	Hydth_0441

TAL:

Thal_1111

SUL:	SYO3AOP1_0048

PMX:	PERMA_0891

NDE:	NIDE1367(nirA)

NLI:	G3M70_17630

AFU:

AF_0164

HDL:	HALDL1_02570

HHB:	Hhub_1037(nirA) Hhub_2082(nasD)

HJE:	HacjB3_00040 HacjB3_01275 HacjB3_10150

HALR:

EFA46_002125 EFA46_013150

HMA:	rrnAC2625(nirA1) rrnAC2992(nirA2)

HHI:	HAH_0254(nirA1) HAH_3043(nirA2)

HHN:	HISP_01355 HISP_15485

HAB:	SG26_07585 SG26_09190

HTA:	BVU17_01250 BVU17_14795

HALJ:

G9465_01585 G9465_02255

NPH:	NP_1146A(nirA2) NP_4224A(nasD)

NMO:	Nmlp_2080(nirA2)

HUT:	Huta_0176 Huta_1327 Huta_1758

HTI:

HTIA_1351

HALA:

Hrd1104_09215 Hrd1104_11580

HMU:

Hmuk_0435

HALZ:

E5139_05435

HALL:

LC1Hm_2961(nirA)

HALI:

BV210_07285 BV210_10255

HSN:	DV733_06385

HRR:	HZS55_01900 HZS55_04890 HZS55_06930

HPEL:

HZS54_01850 HZS54_04965 HZS54_07465

HLT:	I7X12_08215 I7X12_11405

HARC:

HARCEL1_09115 HARCEL1_13190

HWA:	HQ_1116A(nirA2) HQ_2212A(nasD)

HWC:	Hqrw_1146(nirA2) Hqrw_2438(nasD)

HVO:	HVO_1788(nirA1)

HME:	HFX_1918(nirA2) HFX_2005(nasD) HFX_6482(cysI)

HGI:	ABY42_08910 ABY42_09275

HALE:

G3A49_12220 G3A49_12555

HBO:	Hbor_04420 Hbor_39920

HAQ:	DU484_02655

HAJ:	DU500_03060

HAER:

DU502_00855 DU502_01295

HRA:	EI982_12305 EI982_12745

HLM:	DV707_14285

HALM:

FCF25_00575

HLA:	Hlac_0864 Hlac_1407

HALP:

DOS48_03825

SRUB:

C2R22_02730 C2R22_18130

HAE:	halTADL_2896 halTADL_3328

HALG:

HUG10_08715 HUG10_08910

HALU:

HUG12_07180 HUG12_07420 HUG12_20530

HTU:	Htur_0174 Htur_0241 Htur_2855 Htur_3039

HDA:	BB347_12795 BB347_15145

HJT:	DVR14_08725 DVR14_10140 DVR14_12965

HALY:

HYG82_12940 HYG82_14635

HSAL:

JMJ58_08010 JMJ58_08415 JMJ58_14155

NMG:	Nmag_1601(nirA)

HXA:	Halxa_1302 Halxa_1554 Halxa_1971

NAT:

NJ7G_0304

NPE:	Natpe_0146 Natpe_0726 Natpe_3733

NVR:	FEJ81_00770 FEJ81_18040

NPL:	FGF80_01025 FGF80_16740

NOU:	Natoc_0113 Natoc_2772 Natoc_3905 Natoc_4171

SALI:

L593_06170

HLR:	HALLA_05300 HALLA_18995

NAJ:	B1756_07610

NBG:	DV706_21510

NAS:	GCU68_03980 GCU68_05195

MSE:

Msed_0880

MHK:	DFR87_00445

MPRU:

AMAN:

AAMB:

SAZO:

PAI:

VDI:

VMO:

CSY:	CENSYa_0360

» show all

Reference

1 [PMID:4381617]

Authors

Joy KW, Hageman RH.

Title

The purification and properties of nitrite reductase from higher plants, and its dependence on ferredoxin.

Journal

Biochem J 100:263-73 (1966)
DOI:10.1042/bj1000263

Reference

2 [PMID:5954064]

Authors

Ramirez JM, Del Campo FF, Paneque A, Losada M.

Title

Ferredoxin-nitrite reductase from spinach.

Journal

Biochim Biophys Acta 118:58-71 (1966)
DOI:10.1016/s0926-6593(66)80144-3

Reference

3 [PMID:4390523]

Authors

Zumft WG, Paneque A, Aparicio PJ, Losada M.

Title

Mechanism of nitrate reduction in Chlorella.

Journal

Biochem Biophys Res Commun 36:980-6 (1969)
DOI:10.1016/0006-291X(69)90300-3

Other DBs

ExplorEnz - The Enzyme Database:

1.7.7.1

IUBMB Enzyme Nomenclature:

1.7.7.1

ExPASy - ENZYME nomenclature database:

1.7.7.1

BRENDA, the Enzyme Database:

1.7.7.1

CAS:	37256-44-3

DBGET integrated database retrieval system