KEGG   ENZYME: 1.8.1.21Help
Entry
EC 1.8.1.21                 Enzyme                                 

Name
dissimilatory dimethyldisulfide reductase
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
methanethiol:NAD+ oxidoreductase (dimethyl disulfide-forming)
Reaction(IUBMB)
2 methanethiol + NAD+ = dimethyl disulfide + NADH + H+ [RN:R12457]
Reaction(KEGG)
Substrate
methanethiol [CPD:C00409];
NAD+ [CPD:C00003]
Product
dimethyl disulfide [CPD:C08371];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme's activity has been demonstrated in the bacterium Thiobacillus thioparus E6. The methanethiol formed is eventually oxidized to sulfate and carbon dioxide, and the latter assimilated for autotrophic growth.
History
EC 1.8.1.21 created 2019
Reference
1
  Authors
Smith, N. A. and Kelly, D. P.
  Title
Isolation and physiological characterization of authotrophic sulphur bacteria oxidizing dimethyldisulphide as sole source of energy.
  Journal
J Gen Microbiol 134:1407-1417 (1988)
Reference
2
  Authors
Smith, N. A. and Kelly, D. P.
  Title
Mechanism of oxidation of dimethyl disulphide by Thiobacillus thioparus E6.
  Journal
J Gen Microbiol 134:3031-3039 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 1.8.1.21
IUBMB Enzyme Nomenclature: 1.8.1.21
ExPASy - ENZYME nomenclature database: 1.8.1.21
BRENDA, the Enzyme Database: 1.8.1.21

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