| Entry |
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| Name |
phosphoadenylyl-sulfate reductase (thioredoxin);
PAPS reductase, thioredoxin-dependent;
PAPS reductase;
thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase;
3'-phosphoadenylylsulfate reductase;
thioredoxin:3'-phospho-adenylylsulfate reductase;
phosphoadenosine-phosphosulfate reductase;
adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)
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| Class |
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor
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| Sysname |
adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)
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| Reaction(IUBMB) |
adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin [RN: R02021]
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| Reaction(KEGG) |
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| Substrate |
adenosine 3',5'-bisphosphate [CPD: C00054];
sulfite [CPD: C00094];
thioredoxin disulfide [CPD: C00343]
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| Product |
3'-phosphoadenylyl sulfate [CPD: C00053];
thioredoxin [CPD: C00342]
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| Comment |
Specific for PAPS. The enzyme from Escherichia coli will use thioredoxins from other species.
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| History |
EC 1.8.4.8 created 1999 as EC 1.8.99.4, transferred 2000 to EC 1.8.4.8
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K00390 | phosphoadenosine phosphosulfate reductase |
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| Genes |
| SMO: | SELMODRAFT_270214 SELMODRAFT_270602 |
| NCS: | NCAS_0A15090(NCAS0A15090) |
| NDI: | NDAI_0J00250(NDAI0J00250) |
| TPF: | TPHA_0G00330(TPHA0G00330) |
| TBL: | TBLA_0F02980(TBLA0F02980) |
| TDL: | TDEL_0H00480(TDEL0H00480) |
| KAF: | KAFR_0B00460(KAFR0B00460) |
| KNG: | KNAG_0F03790(KNAG0F03790) |
| CAL: | CAALFM_C407030WA(MET16) |
| NTE: | NEUTE1DRAFT118520(NEUTE1DRAFT_118520) |
| PTKZ: | JDV02_000493(MET16) |
| ANG: | ANI_1_1258094(An11g09780) |
| ZTR: | MYCGRDRAFT_101851(MGSUL7) |
| TML: | GSTUM_00001561001 GSTUM_00002663001 |
| ABP: | AGABI1DRAFT72675(AGABI1DRAFT_72675) |
| ABV: | AGABI2DRAFT188563(AGABI2DRAFT_188563) |
| SCM: | SCHCO_02622365(SCHCODRAFT_02622365) |
| MLR: | MELLADRAFT_28037 MELLADRAFT_37430 |
| SMIN: | v1.2.008330.t1(symbB.v1.2.008330.t1) v1.2.024590.t1(symbB.v1.2.024590.t1) |
| GTT: | GUITHDRAFT_159090 GUITHDRAFT_54190 GUITHDRAFT_72734 GUITHDRAFT_95252 |
| ECOO: | ECRM13514_3617(cysH) |
| ECOH: | ECRM13516_3483(cysH) |
| ECW: | EcE24377A_3064(cysH) |
| EDJ: | ECDH1ME8569_2672(cysH) |
| ECOI: | ECOPMV1_03015(cysH) |
| REE: | electrica_00942(cysH) |
| CLAP: | NCTC11466_00741(cysH) |
| KIE: | NCTC12125_04931(cysH) |
| AHN: | NCTC12129_03957(cysH) |
| METY: | MRY16398_10360(cysH) |
| PTF: | PROFFT_A_02830(cysH) |
| PSHI: | SAMEA2665130_2712(cysH) |
| YPI: | YpsIP31758_3309(cysH) |
| SMW: | SMWW4_v1c07940(cysH) |
| SFJ: | SAMEA4384070_0843(cysH) |
| SOF: | NCTC11214_00685(cysH) |
| EHD: | ERCIPSTX3056_604(cysH) |
| BAPF: | BUMPF009_CDS00173(cysh) |
| BAPG: | BUMPG002_CDS00173(cysh) |
| BAPU: | BUMPUSDA_CDS00173(cysh) |
| BAPW: | BUMPW106_CDS00173(cysh) |
| TPTY: | NCTC11468_00913(cysH) |
| PHEI: | NCTC12003_00944(cysH) |
| PRJ: | NCTC6933_03107(cysH) |
| LRI: | NCTC12151_01215(cysH) |
| HPIT: | NCTC13334_01948(cysH) |
| ALIG: | NCTC10568_02232(cysH) |
| PAET: | NCTC13378_01290(cysH) |
| XFU: | XFF4834R_chr13170(cysH) |
| XPH: | XppCFBP6546_17600(XppCFBP6546P_17600) |
| XHD: | LMG31886_10520(cysH) |
| VAU: | VANGNB10_cI0264(cysH) |
| VPL: | SA104470976_02333(cysH) |
| PAEB: | NCGM1900_4809(cysH) |
| PAER: | PA1R_gp5333 PA1R_gp5373 |
| PVD: | CFBP1590__2128(cysH) |
| PPRC: | PFLCHA0_c18850(cysH) |
| PMUD: | NCTC8068_01555(cysH) |
| PPUU: | PputUW4_03665(cysH) |
| PTW: | TUM18999_19540(cysH) |
| PTAE: | NCTC10697_01180(cysH) |
| MSHE: | MAALD49_18810(cysH) |
| PSYC: | DABAL43B_1428(cysH) |
| ABAL: | ABLAC_07060 ABLAC_18060 |
| ACUM: | C9E88_016115 C9E88_16870 |
| MCAT: | MC25239_00133(cysH) |
| SCAA: | TUM17387_31230(cysH) |
| SALH: | HMF8227_02029(cysH) |
| GIL: | NHM04_02000 NHM04_02085 |
| MISZ: | MishRS11D_28170(cysH) |
| APRS: | BI364_05130 BI364_07445 |
| GAI: | IMCC3135_20220(cysH) |
| HAHE: | ENC22_11965 ENC22_18300 |
| HPRO: | LMS44_07585 LMS44_14465 |
| TOR: | R615_04470 R615_09450 |
| AEL: | NCTC12917_00961(cysH) |
| CHJ: | NCTC10426_01799(cysH) |
| SOK: | D0B54_19785 D0B54_20325 |
| CDIZ: | CEDIAZO_00779(cysH) |
| NME: | NMB1155(cysH-1) NMB1193(cysH-2) |
| NMM: | NMBM01240149_0974(cysH) |
| NMS: | NMBM01240355_1119(cysH) |
| NMQ: | NMBM04240196_1008(cysH) |
| NMZ: | NMBNZ0533_1166(cysH) |
| NMX: | NMA510612_1515(cysH) |
| NZO: | SAMEA4504057_1832(cysH) |
| NCI: | NCTC10296_00711(cysH) |
| NANI: | NCTC12227_00615(cysH) |
| BPM: | BURPS1710b_1168(cysH) |
| PLG: | NCTC10937_02261(cysH) |
| BUO: | BRPE64_ACDS06280(cysH) |
| AXX: | ERS451415_01635(cysH) |
| LIM: | L103DPR2_01896(cysH) |
| LIH: | L63ED372_01721(cysH) |
| NIT: | NAL212_0644 NAL212_2199 |
| NII: | Nit79A3_0316 Nit79A3_0773 Nit79A3_3386 |
| NCO: | AAW31_00980 AAW31_16035 |
| NUR: | ATY38_02705 ATY38_09765 |
| URU: | DSM104443_02695(cysH) |
| UPL: | DSM104440_02418(cysH) |
| MOH: | IHQ72_09380 IHQ72_30990 |
| MMEI: | LRP31_08705 LRP31_30445 |
| RBS: | RHODOSMS8_01378(cysH) |
| SMEL: | SM2011_c00092(cysH) |
| SFD: | USDA257_c06700(cysH) |
| SAME: | SAMCFNEI73_Ch1004(cysH) |
| AGR: | AGROH133_04513(cysH) |
| AVV: | RvVAT039_24490(cysH) |
| AVF: | RvVAR031_11760(cysH) |
| REC: | RHECIAT_CH0001213(cysH) |
| REL: | REMIM1_CH01133(cysH) |
| REP: | IE4803_CH01155(cysH) |
| REI: | IE4771_CH01195(cysH) |
| RGA: | RGR602_CH01055(cysH) |
| RPHA: | AMC79_CH01173(cysH) |
| NEN: | NCHU2750_06530(cysH) |
| BIO: | BR141012304_10387(cysH) |
| VGO: | GJW-30_1_00825(cysH) |
| MAQU: | Maq22A_c18940(cysH) |
| MTUN: | MTUNDRAET4_0746(cysH) |
| FIL: | BN1229_v1_0945(cysH) BN1229_v1_3245 |
| FIY: | BN1229_v1_0948(cysH) BN1229_v1_2678 |
| TSV: | DSM104635_03093(cysH) |
| RLI: | RLO149_c014610(cysH) |
| PHP: | PhaeoP97_02073(cysH) |
| PPIC: | PhaeoP14_01888(cysH) |
| OTM: | OSB_06760(cysH_1) OSB_12820(cysH_2) |
| RED: | roselon_01349 roselon_02539 |
| SINL: | DSM14862_01213(cysH) |
| SPSE: | SULPSESMR1_01157(cysH) |
| RMM: | ROSMUCSMR3_00400(cysH) |
| AHT: | ANTHELSMS3_03263(cysH) |
| LALG: | LentiSH36_01454(cysH) |
| RSU: | NHU_00528(cysH) NHU_02417(cysH) |
| RHM: | B5V46_07550 B5V46_15300 |
| LVS: | LOKVESSMR4R_01165(cysH) |
| PPAF: | I8N54_10215 I8N54_19955 |
| THAS: | C6Y53_00130 C6Y53_04300 |
| SBIN: | SBA_ch1_32020(cysH) |
| SFLA: | SPHFLASMR4Y_00659(cysH) |
| PALG: | HFP57_01675 HFP57_13690 |
| RAP: | RHOA_4196(cysH) RHOA_5599(cysH) |
| SINU: | IMZ28_07195 IMZ28_07200 |
| BSU: | BSU10930(yitB) BSU15570(cysH) |
| BSR: | I33_1228(yitB) I33_1744 |
| BSH: | BSU6051_10930(yitB) BSU6051_15570(cysH) |
| BSY: | I653_05530 I653_08010 |
| BSUT: | BSUB_01190(yitB) BSUB_01688(cysH) |
| BSUL: | BSUA_01190(yitB) BSUA_01688(cysH) |
| BSUS: | Q433_06175 Q433_08940 |
| BSN: | BSn5_17360 BSn5_19895 |
| BSQ: | B657_10930(yitB) B657_15570(cysH) |
| BSX: | C663_1116(yitB) C663_1601(cysH) |
| BSP: | U712_05595 U712_08200 |
| BSS: | BSUW23_05540(yitB) BSUW23_08015(cysH) |
| BST: | GYO_1399(yitB) GYO_1906 |
| BIT: | BIS30_16175 BIS30_18630 |
| BLI: | BL01979(yitB) BL02282(cysH) |
| BLD: | BLi01778(cysH1) BLi02154(cysH2) |
| BLH: | BaLi_c18110(cysH) BaLi_c22290(yitB) |
| BAZ: | BAMTA208_09365(cysH) |
| BAE: | BATR1942_03100 BATR1942_05580 |
| BSON: | S101395_02482(cysH) S101395_03175 |
| BHT: | DIC78_01605 DIC78_04135 |
| BMOJ: | HC660_11480(yitB) HC660_16220(cysH) |
| BTEQ: | G4P54_05780 G4P54_08140 |
| BIQ: | AN935_05665 AN935_08135 |
| BSTR: | QI003_05895(yitB) QI003_08385(cysH) |
| BGY: | BGLY_1772(cysH) BGLY_2294 |
| BBAD: | K7T73_08080 K7T73_17350 |
| BCAB: | EFK13_06150 EFK13_08610 |
| BRY: | M0696_06060 M0696_08465 |
| BACI: | B1NLA3E_03515 B1NLA3E_07905 |
| GST: | HW35_17430 HW35_17480 |
| BACY: | QF06_04400 QF06_06810 |
| BACL: | BS34A_12070(yitB) BS34A_17260(cysH) |
| BALM: | BsLM_1138 BsLM_1655 |
| PARG: | PspKH34_34030(cysH) |
| ASED: | IRT44_00975 IRT44_10705 |
| LAO: | AOX59_10770 AOX59_16030 |
| AQT: | FN924_04665 FN924_12210 |
| BTHV: | CQJ30_05060 CQJ30_09400 |
| NDT: | L1999_01920 L1999_12120 |
| NCM: | QNK12_02410 QNK12_10680 |
| NNV: | QNH39_11890 QNH39_14250 |
| BLEN: | NCTC4824_02179(cysH) |
| BCOA: | BF29_2522 BF29_2599 BF29_2735 |
| SFOR: | QNH23_04120 QNH23_17360 |
| SPIC: | SAMEA4384060_2469(cysH) |
| SSTE: | SAMEA4384403_0215(cysH) |
| BBE: | BBR47_16150 BBR47_42670(cysH) |
| BFM: | BP422_03265 BP422_17030 |
| BAGR: | BA6348_09660 BA6348_20860 |
| BCHS: | JNE38_08925 JNE38_22295 |
| BPAB: | PSE45_08045 PSE45_19990 |
| BAYD: | BSPP4475_04930 BSPP4475_14825 |
| PPQ: | PPSQR21_045030(cysH) |
| PSOP: | KP014_20355 KP014_28215 |
| COHN: | KCTCHS21_53990(cysH) |
| AACO: | K1I37_04205 K1I37_18650 |
| ADAU: | NZD86_04735 NZD86_21010 |
| AFAS: | NZD89_04800 NZD89_25990 |
| EFF: | skT53_22770(cysH) skT53_34280(yitB) |
| KPUL: | GXN76_05250 GXN76_13040 |
| KEB: | GXN75_06200 GXN75_14760 |
| LACY: | A4V08_09805 A4V08_32320 |
| THEF: | E1B22_03390 E1B22_11665 |
| SAY: | TPY_0738(cysH) TPY_2304(cysH) |
| SAP: | Sulac_2900 Sulac_3563 |
| SDIA: | QU667_06175 QU667_10590 |
| MPA: | MAP_2036(cysH) MAP_2209(cysH) |
| MAVI: | RC58_08055 RC58_08940 |
| MAVU: | RE97_08055 RE97_08945 |
| MCHI: | AN480_09065 AN480_26895 |
| MMAN: | MMAN_18730(cysH_1) MMAN_23160(cysH_2) |
| MSA: | Mycsm_04104 Mycsm_07118 Mycsm_07256 |
| MUL: | MUL_2696(cysH_1) MUL_3653(cysH) |
| MMI: | MMAR_3417(cysH_1) MMAR_3711(cysH) |
| MMAE: | MMARE11_33250(cysH_1) MMARE11_36180(cysH) |
| MLI: | MULP_03683(cysH_1) MULP_03961(cysH) |
| MSHO: | MSHO_32320(cysH_1) MSHO_48280(cysH_2) |
| MKN: | MKAN_03835 MKAN_04970 |
| MNV: | MNVI_00960(cysH_1) MNVI_38680(cysH_2) |
| MPAG: | C0J29_20700 C0J29_31640 |
| MBAI: | MB901379_03062(cysH_1) MB901379_03295(cysH_2) |
| MSEO: | MSEO_20280(cysH_1) MSEO_21980(cysH_2) |
| MHEK: | JMUB5695_01970(cysH) |
| MMAM: | K3U93_12255 K3U93_15835 |
| MOT: | LTS72_06185 LTS72_07325 |
| MMEH: | M5I08_06185 M5I08_09380 M5I08_12280 M5I08_24645 |
| MKY: | IWGMT90018_20920(cysH) |
| MPHL: | MPHLCCUG_03501(cysH) |
| MRH: | MycrhN_2888 MycrhN_4313 |
| MTHN: | 4412656_02816(cysH) |
| MAUU: | NCTC10437_03658(cysH) |
| MFLV: | NCTC10271_01755(cysH) |
| MSAL: | DSM43276_01523(cysH) |
| MTER: | 4434518_01414(cysH) |
| CMIN: | NCTC10288_00241(cysH) |
| CRL: | NCTC7448_00572(cysH) |
| CCYS: | SAMEA4530656_0003(cysH) |
| NFR: | ERS450000_02696(cysH) |
| NAD: | NCTC11293_02411(cysH) |
| NWL: | NWFMUON74_53410(cysH) |
| NIE: | KV110_01405 KV110_10045 |
| NSPU: | IFM12276_47800(cysH) |
| RHA: | RHA1_ro01252(cysH) RHA1_ro10068 RHA1_ro11012 |
| RER: | RER_37470(cysH) RER_pREL1-00830 |
| REB: | XU06_17490 XU06_31290 |
| ROP: | ROP_09720(cysH) ROP_pROB01-00800 ROP_pROB01-05620 |
| RFA: | A3L23_03785(cysH_1) A3L23_05017(cysH_2) |
| RCR: | NCTC10994_04134(cysH) |
| ROZ: | CBI38_11545 CBI38_36445 |
| RPSK: | JWS13_00245 JWS13_02690 JWS13_03920 JWS13_39960 |
| GHN: | MVF96_15790 MVF96_23970 |
| TPUL: | TPB0596_17020(cysH) |
| SAMB: | SAM23877_5819(cysH) |
| SLE: | sle_15750(sle_15750) |
| SGM: | GCM10017557_17150(cysH) |
| SLX: | SLAV_09560(cysH1) SLAV_39780(cysH2) |
| SAST: | CD934_05955 CD934_07275 |
| SFUG: | CNQ36_26110 CNQ36_29735 |
| STUI: | GCM10017668_56080(cysH) |
| SXT: | KPP03845_105757(cysH) |
| AMAU: | DSM26151_28850(cysH) |
| AMAV: | GCM10025877_25450(cysH) |
| CPRT: | FIC82_016235 FIC82_020645 |
| DSS: | GCM25873_25680(cysH) |
| PAUS: | NCTC13651_01541(cysH) |
| NCA: | Noca_2349 Noca_3794 Noca_4821 Noca_4834 |
| NPI: | G7071_10430 G7071_13295 |
| NAQU: | ENKNEFLB_02913(cysH) |
| KUT: | JJ691_12580 JJ691_57500(cysH) |
| ACTA: | C1701_18825 C1701_22810 |
| MSAG: | GCM10017556_14980(cysH) |
| ACTR: | Asp14428_58330(cysH) |
| PFLA: | Pflav_005070(cysH_1) Pflav_080700(cysH_2) |
| ANE: | ATCC27039_13550(cysH) |
| AHW: | NCTC11636_00691(cysH) |
| ASLA: | NCTC11923_02328(cysH) |
| AVC: | NCTC10951_01214(cysH) |
| BALA: | DSM104299_05401(cysH) |
| SBAE: | DSM104329_05307(cysH) |
| SYR: | SynRCC307_0390(cysH) |
| SYX: | SynWH7803_2174(cysH) |
| SYP: | SYNPCC7002_A1497(cysH) |
| SYH: | Syncc8109_2391(cysH) |
| SYNW: | SynWH8103_02482(cysH) |
| DSL: | Dacsa_0255 Dacsa_2435 |
| AMR: | AM1_0350(cysH) AM1_0876(cysH) |
| TVN: | NIES2134_107140(cysH) |
| LET: | O77CONTIG1_01145(cysH) |
| KOV: | K9N68_14270(cysH) K9N68_38300 |
| LSC: | KIK02_16235 KIK02_23585(cysH) |
| LSK: | J5X98_04075 J5X98_11180(cysH) |
| HHG: | XM38_042940(cysH_1) XM38_045330(cysH_2) |
| GLP: | Glo7428_2845 Glo7428_4018 |
| CHON: | NIES4102_22590 NIES4102_33030 |
| MVZ: | myaer102_46720(cysH) |
| CYN: | Cyan7425_2865 Cyan7425_3330 |
| MIC: | Mic7113_1852 Mic7113_4948 |
| MPRO: | BJP34_19450 BJP34_30990 |
| GML: | ISF26_04435 ISF26_23995 |
| RIV: | Riv7116_5071 Riv7116_6049 |
| NSPH: | BDGGKGIB_01816(cysH) |
| STAN: | STA3757_19030(cysH) |
| PMET: | G4Y79_01190 G4Y79_06925 |
| OBG: | Verru16b_01224(cysH) |
| OBT: | OPIT5_03930 OPIT5_10670 |
| LCRE: | Pla8534_35410(cysH) |
| PLH: | VT85_19720(cysH_1) VT85_26575(cysH_2) |
| GES: | VT84_09455 VT84_33335(cysH) |
| ALKQ: | M9189_00290 M9189_06165 |
| HHY: | Halhy_1817 Halhy_5887 |
| SMIZ: | 4412673_02154(cysH) |
| SDJ: | NCTC13534_03108(cysH) |
| STHA: | NCTC11429_04458(cysH) |
| CMR: | Cycma_0676 Cycma_1052 |
| CAMU: | CA2015_0582 CA2015_0949 |
| PSEZ: | HME7025_02274(cysH) |
| RHOZ: | GXP67_13405 GXP67_16230 |
| MTT: | Ftrac_1006 Ftrac_2991 |
| FPF: | DCC35_09885 DCC35_15205 |
| CLIT: | OQ292_14700 OQ292_19390 |
| FBT: | D770_06265 D770_21300 |
| FMM: | LVD15_12240 LVD15_25290 |
| FUA: | LVD17_03585 LVD17_25980 |
| FLW: | LVD16_11285 LVD16_25130 |
| PRHO: | PZB74_00355 PZB74_15870 |
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