KEGG ENZYME: 1.8.5.1

ENZYME: 1.8.5.1

Entry

EC 1.8.5.1                  Enzyme

Name

glutathione dehydrogenase (ascorbate);
dehydroascorbic reductase;
dehydroascorbic acid reductase;
glutathione dehydroascorbate reductase;
DHA reductase ;
dehydroascorbate reductase;
GDOR;
glutathione:dehydroascorbic acid oxidoreductase

Class

Oxidoreductases;
Acting on a sulfur group of donors;
With a quinone or similar compound as acceptor

Sysname

glutathione:dehydroascorbate oxidoreductase

Reaction(IUBMB)

2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate [RN:R01108]

Reaction(KEGG)

R01108

Substrate

glutathione [CPD:C00051];
dehydroascorbate [CPD:C05422]

Product

glutathione disulfide [CPD:C00127];
ascorbate [CPD:C00072]

History

EC 1.8.5.1 created 1961

Pathway

ec00053

Ascorbate and aldarate metabolism

ec00480

Glutathione metabolism

ec01100

Metabolic pathways

Orthology

K21888

glutathione dehydrogenase/transferase

K29001

glutathione dehydrogenase/transferase

Genes

PFLL:

139141784

EAF:

111711828

PCAN:

112571966

LSAX:

138964156

BARL:

143284993

HRF:

124136020

HRJ:

124274675

HASI:

137295894

MYI:

110441083

PMAX:

117331608

AIRR:

138305001

YBA:

132560713

MMER:

123525413

RPHI:

132743760

ATEN:

116304405

XEN:

124441006

TAD:	TRIADDRAFT_56715

CCLM:

134177221

OSA:	4337622 4340581

DOSA:

Os05g0116100 Os06g0232600

OBR:	102709006 102719584

OGL:	127773260 127776011

BDI:	100823882 100830397

ATS:	109765491 109782434

TDC:	119318465 119330127 119337564 119360867

TAES:

123076802 123076809 123076818 123105935 123149683 123156637 123164852 123180069 543069

TUA:	125519426 125544581

HVG:	123408438 123451934

LPER:

127317533 127343142

LRD:	124647344 124685391 124685427 124708242

SBI:	110431218 8067348 8067349

ZMA:	100191219(dhar3) 100273125(dhar1) 100285047(dhar4) 100382696(dhar2)

MFLO:

136512352 136514016 136514017 136516368 136517931 136527542

SITA:

101759688 101769608

SVS:	117850548 117853206

PVIR:

120664052 120667827 120670112 120697269 120703055

PHAI:

112887710 112890073

PAUA:

133926571 133928308 133930569

TANG:

140765501 140775288

CROT:

144568558(DHAR3) 144574704

PDA:	103706622 103710555 103719938

EGU:	105044500 105053239 105057001

MUS:	135615863 135617555 135626905 135626918

ZOF:	121989275 122002718 122006961 122038808

DCT:	110094742 110105563

PEQ:	110024161 110027478

AOF:	109821733 109829920 109849073

ATH:	AT1G19550 AT1G19570(DHAR1) AT1G75270(DHAR2) AT5G16710(DHAR3)

ALY:	110227884 9304537 9323647 9326409

CRB:	17884168 17895904 17898354

CSAT:

104702262 104705963 104713173 104735705 104740653 104751400 104756300 104769957 104776068

EUS:	EUTSA_v10008761mg EUTSA_v10014453mg EUTSA_v10019864mg

BRP:	103835841 103846305 103851061 103852942 103872760

BNA:	106346950 106357292 106371989 106375652 106387685 106397189 106401061 106440767 106449347 125575024 125594897

BOE:	106292345 106295217 106309564 106315292 106315491 106322741 106338740

RSZ:	108805309 108814496 108816015 108821023 108841068 108843573 108856963 130498732 130499541

THJ:	104827191 104827305

CPAP:

110809731 110824209

CIT:	102620936 102629685

CIC:	CICLE_v10012501mg

PVY:	116115920 116126915

MINC:

123197901 123228042 123230317

TCC:	18586245 18601869

GRA:	105776802 105780418 105789278

GHI:	107887344 107897777 107925966 107930662 107953969 107959887

GAB:	108458125 108470682 108480636

HSYR:

120115371 120140101 120161231 120182767 120205539 120213283

DZI:	111294215 111296873 111310245 111313584

EGR:	104422157 104454151 104454260

RARG:

115745336 115752102

GMX:	100306061(DHAR4) 100805216(DHAR2) 100819803(DHAR1) 732557(DHAR3)

GSJ:	114370026 114381018 114394539 114403797

PVU:	137814961 137828740

VRA:	106756718 106769672

VAR:	108324205 108329329

VUN:	114173710 114189983

VUM:	124832730 124834120 124846323

CCAJ:

109792184 109806919

APRC:

113849681 113872224

MTR:	25485729 25489243

TPRA:

123902358 123913780 123918283

CAM:	101496317 101503639

PSAT:

127083802 127098111 127126936

VVO:	131629636 131649076 131661841

LJA:	130718101 130723881

ADU:	107467663 107481050 107485017

AIP:	107611072 107618632

AHF:	112712312 112733706 112770022 112776849 112791636

LANG:

109335897 109345126 109354486 109359087

PCIN:

129293686 129297926

QSA:	O6P43_005722 O6P43_014301

FVE:	101303648 101305509 101312105 105353026

AANS:

126782627 126792063

RCN:	112184608 112195020

PPER:

18784488 18787430

PMUM:

103328578 103332585

PAVI:

110755157 110756668

PDUL:

117619943 117622957

MDM:	103432300 103433463(DHAR) 103435916 103444197

MSYL:

126583417(LOC126583417) 126622992(LOC126622992) 126628119(LOC126628119)

PXB:	103927266 103928568 103936763 103948366 103959477

PCOX:

137708313 137720041 137735068 137738892

ZJU:	107413560 107416296

MNT:	21408127 21409825

CSAV:

115698725 115702075 115702896 115707810

HLP:	133787766 133797587 133817732 133818627

CSV:	101203335 101203666

CMO:	103496793 103500187

BHJ:	120070347 120081792

MCHA:

111010278 111010279 111013239

CMAX:

111476861 111482062 111483874 111483885

CMOS:

111442357 111448000 111448001 111458209

CPEP:

111789995 111791405 111806122 111806146

RCU:	8260840 8260843 8287964

MEAN:

126660773 126661381 126679046

JCU:	105634679(DHAR) 105638586

HBR:	110663890 110664808 110671418

MESC:

110601236 110623873

POP:	18099386 7469797 7489598

PEU:	105123341 105123470 105127481

PALZ:

118039628 118052231 118059885

PNZ:	133670562 133697352 133704713

JRE:	108988174 109007806 109022303 109022305

CILL:

122290216 122301238 122302890 122308076

CAVE:

132186879

AGLU:

133859386 133864710

QSU:	112002186 112035702

QLO:	115955933 115967123 115975953

CSAA:

142621766 142640487

TWL:	119980794 119989506 119989527 120012094

VVI:	100233050(DHAR) 100258402

VRI:	117929237 117929912

SLY:	101254215 101257804 778229(DHAR1) 778343(DHAR2)

SPEN:

107004866 107020618

SOT:	102577622(DHAR) 102577766(DHAR2) 102598042

SSTN:

125843897 125867684

SDUL:

129881041 129896948

SVER:

125819651 125836900

CANN:

107870482 107871328

LBB:	132613999 132640164

NTA:	107773610 107777254 107819842

NSY:	104227810 104243291

NTO:	104112793 104114192

NAU:	109213372 109218056

INI:	109177910 109186899

ITR:	116000003 116012783

SIND:

105171922 105176366

OEU:	111385880 111389223

EGT:	105959293 105962725

SSPL:

121760121 121763473 121765800 121783291 121786266

SMIL:

131005988 131009525 131021890

SHIS:

125201649 125209964 125211838

APAN:

127241278 127261988

HPUM:

140870713

PHUA:

140973933

PEBU:

140824301 140834082

PTAB:

142538268 142555166

CARB:

113701218 113725530 113730556 140010495

HAN:	110872537 110888227 110893651 110896725 110909251 110933878 118481235

BHW:	143538897 143549656 143569424 143584497 143588919 143601063 143610683 143637552

ECAD:

122585089 122603356 122603675

LSV:	111883404(DHAR3) 111888975(LOC111888975) 111888985(LOC111888985)

CCAV:

112519586(LOC112519586)

DCR:	108197400 108203465

AGRV:

141663894 141697072 141703090

CSIN:

114274471 114275044 114278095

RVL:	131300537 131304048 131318773

AEW:	130758469 130763539 130777636 130781758

DLT:	127798168 127804289

CFLO:

132266250 132312005

BVG:	104887241(LOC104887241) 104906117(LOC104906117)

SOE:	110774995 110799104

CQI:	110696661 110706021 110730692 110735130

CALB:

145586236(LOC145586236) 145590585(LOC145590585) 145593591(LOC145593591) 145596195(LOC145596195) 145641752(LOC145641752) 145641862(LOC145641862)

ATRI:

130802406 130802709 130804335

SLAF:

141606070 141611947 141639762

MOF:	131160419 131165588

NNU:	104594651 104599264 104609976

MING:

122069365 122078463

TSS:	122650273 122652929

PSOM:

113275549 113282063 113307676 113310919 113314260 113322673 113322725

MSIN:

131243575 131251438 131253021

ACAK:

137936611 137955869 137965629

NCOL:

116254866 116255819

ATR:	18422040 18434119

CJF:

131041873

SMO:	SELMODRAFT_139875 SELMODRAFT_159481 SELMODRAFT_168685 SELMODRAFT_233824 SELMODRAFT_271409 SELMODRAFT_422242

PPP:	112273233 112275199 112292200

CRE:	CHLRE_10g456750v5

MNG:

MNEG_0969

CSL:	COCSUDRAFT_31289 COCSUDRAFT_45129

CVR:	CHLNCDRAFT_143262

APRO:

F751_6478

SCE:	YGR154C(GTO1) YKR076W(ECM4) YMR251W(GTO3)

SEUB:

DI49_3446 DI49_4335

SPAO:

SPAR_G03690 SPAR_K02790 SPAR_M03660

KLA:	KLLA0_F12056g

KMX:	KLMA_20130(ECM4)

LTH:	KLTH0F17622g

VPO:	Kpol_489p16 Kpol_489p17

ZRO:	ZYRO0B09922g

CGR:	2888060(ECM4)

NCS:	NCAS_0A03430(NCAS0A03430) NCAS_0J00110(NCAS0J00110)

NDI:	NDAI_0A03260(NDAI0A03260) NDAI_0B01870(NDAI0B01870) NDAI_0B06370(NDAI0B06370) NDAI_0D01360(NDAI0D01360) NDAI_0F00100(NDAI0F00100)

TPF:	TPHA_0C04090(TPHA0C04090)

TBL:	TBLA_0G01970(TBLA0G01970)

TGB:	HG536_0H02580

TDL:	TDEL_0B02560(TDEL0B02560)

KAF:	KAFR_0A04880(KAFR0A04880) KAFR_0H00400(KAFR0H00400)

KNG:	KNAG_0C06410(KNAG0C06410) KNAG_0F03100(KNAG0F03100)

ZMK:	HG535_0F05660

SLUD:

SCDLUD_003145

DHA:	DEHA2C16566g DEHA2C16588g

PIC:	PICST_43969(ECM4)

PGU:	PGUG_03861

SPAA:

SPAPADRAFT_59851

LEL:	PVL30_000069(ECM4)

LBG:	92206216(LODBEIA_P10200)

COT:	CORT_0A01520

CAL:	CAALFM_CR02130WA(ECM4)

CTP:	CTRG_00896

CDU:	CD36_27050

CTEN:

18248366(ECM4)

CLU:	CLUG_03766

CLUS:

A9F13_01g03762

CAUR:

CJI96_0001736 CJI96_0002951

ASAU:

88174774(PUMCH_003711)

PPA:	PAS_chr2-1_0315

PKZ:	C5L36_0B11220

BNN:	FOA43_004058

BBRX:

BRETT_002896

OPA:	HPODL_03063

YLI:	2906632(YALI2_C00672g) 2906848(YALI2_B00043g)

SLB:	AWJ20_3344(ECM4)

NCR:	NCU04368 NCU09570

NTE:	NEUTE1DRAFT102651(NEUTE1DRAFT_102651) NEUTE1DRAFT79533(NEUTE1DRAFT_79533)

SMP:	10806078(SMAC4_05712) 10806217(SMAC4_01776)

PAN:	PODANSg6184

PBEL:

QC761_303640(ECM4)

PPSD:

87908567(ECM4)

PPSP:

QC763_303640(ECM4)

PPSA:

QC764_303640(ECM4)

TTT:	THITE_2144537

MTM:	MYCTH_2299397

CTHR:

CTHT_0030670

RTHE:

98125878(VTJ83DRAFT_4714)

MGR:	MGG_01410 MGG_02244

PPEI:

PpBr36_00923 PpBr36_06893

PGRI:

PgNI_04105 PgNI_05448

TMN:	UCRPA7_5959 UCRPA7_6880

SSCK:

SPSK_02582 SPSK_07449 SPSK_10623

FGR:	FGSG_04433 FGSG_09688

FPU:	FPSE_04292 FPSE_09935

FPOA:

FPOAC1_006906 FPOAC1_011959

FVN:	FVRRES_07537 FVRRES_13027

FVR:	FVEG_06294 FVEG_11213 FVEG_13590

FOX:	FOXG_08382 FOXG_13780 FOXG_16651 FOXG_16708 FOXG_16775

NHE:	NECHADRAFT_39661 NECHADRAFT_51934 NECHADRAFT_76152 NECHADRAFT_95795

FFC:	NCS54_00228200 NCS54_01072700 NCS54_01313300

FKR:	NCS57_00223500 NCS57_01066500 NCS57_01299800

FMU:	J7337_004492 J7337_011919 J7337_012376

TRE:	TRIREDRAFT_112633 TRIREDRAFT_56819

TRR:	M419DRAFT_135149

TATV:

25778431(TrAtP1_012052) 25779155(TrAtP1_010211) 25786356(TrAtP1_007463) 25786657(TrAtP1_009963)

TASP:

36612687(TrAFT101_010822) 36614550(TrAFT101_011025) 36619161(TrAFT101_011230) 90966893(TrAFT101_007932)

MAW:	19248288(ECM4) 19248807(J3458_014350)

MAJ:	MAA_07012 MAA_07818

MBRN:

26238058(gto2_0) 26246911(gto2_1)

PCHM:

VFPPC_04964 VFPPC_10730 VFPPC_13580

UVI:	66064370(UV8b_03592)

CMT:

CCM_07575

AMUS:

LMH87_009904

PLJ:	28892999(PLICBS_003914) 90642532(PLICBS_000333)

PTKZ:

JDV02_001918 JDV02_003279(UBA1_2)

VAL:	VDBG_00810

VDA:	VDAG_00421

CFJ:	CFIO01_04709

CLUP:

CLUP02_16216

CDET:

87942688(CDEST_06185) 87944945(CDEST_08442)

SAPO:

SAPIO_CDS6497 SAPIO_CDS7082

ELA:	UCREL1_10599 UCREL1_11693 UCREL1_8429

PFY:	PFICI_02566 PFICI_04151 PFICI_04386

SSL:	SS1G_05554 SS1G_08258

BFU:	BCIN_09g05920 BCIN_12g01340

MBE:	MBM_01973 MBM_07281

PSCO:

LY89DRAFT_617572 LY89DRAFT_680144 LY89DRAFT_693490

GLZ:	GLAREA_02462 GLAREA_04147 GLAREA_09515

ANI:	ANIA_05831 ANIA_10273 ANIA_10379

AFM:	AFUA_2G15770 AFUA_7G06460

ACT:	ACLA_008200 ACLA_074720

NFI:	NFIA_027750 NFIA_091010

AOR:	AO090011000920 AO090012000247

ANG:	An03g05540 An05g00350 An15g06030

AFV:	AFLA_001960 AFLA_008314

ALUC:

AKAW2_50926S AKAW2_60168A(ECM4) AKAW2_60732S

ACHE:

ACHE_60429A(ECM4)

APUU:

APUU_10839S APUU_20474A(ECM4) APUU_80845S

PCS:	N7525_006756 N7525_007147

PDP:	PDIP_24610 PDIP_80930

POU:	POX_d05108

PPSF:

300793149(PFLUO_LOCUS7027) 300793836(PFLUO_LOCUS7646) 300795516(PFLUO_LOCUS9158)

TMF:	EYB26_000079 EYB26_002117 EYB26_005126

TRG:	TRUGW13939_02497

CIM:	CIMG_00933 CIMG_12887(CIMG00293)

CPW:	90964830(D8B26_002216) 9692139(ECM4)

URE:	UREG_00366

ABE:

ARB_07429

TVE:

TRV_02657

PBL:	PAAG_03931

PBN:	PADG_03423

AJE:	HCAG_01006 HCAG_07421

BGH:	BDBG_00859 BDBG_08201

PNO:	SNOG_02588 SNOG_14093

PTE:	PTT_03996 PTT_13161 PTT_14020

PTRR:

6338980(PtrM4_024840) 6340797(PtrM4_061280) 6347349(PtrM4_035430)

BZE:	COCCADRAFT_105127 COCCADRAFT_109935 COCCADRAFT_38161

BSC:	COCSADRAFT_136591 COCSADRAFT_155997 COCSADRAFT_169655

BOR:	COCMIDRAFT_33545 COCMIDRAFT_81270 COCMIDRAFT_84047

AALT:

CC77DRAFT_1030782 CC77DRAFT_1033861 CC77DRAFT_1057147 CC77DRAFT_994099

ADAC:

96082918(ACET3X_002596) 96087648(ACET3X_007326) 96088584(ACET3X_008262)

ARAB:

EKO05_0000171 EKO05_0003071 EKO05_0009023

ZTR:	MYCGRDRAFT_70572 MYCGRDRAFT_95660

PFJ:	MYCFIDRAFT_187791 MYCFIDRAFT_43687 MYCFIDRAFT_44255

FFU:	CLAFUR5_05475 CLAFUR5_05824 CLAFUR5_11025

CBET:

CB0940_05205 CB0940_07224 CB0940_08202

BCOM:

BAUCODRAFT_38792 BAUCODRAFT_67640 BAUCODRAFT_75408

NPA:	UCRNP2_2219 UCRNP2_6962 UCRNP2_9721

TML:	GSTUM_00004090001 GSTUM_00006030001 GSTUM_00010048001

SPO:	2539028(gst4)

SOM:	SOMG_04472(gst4)

CNE:	CNK02300 CNK02340

CNB:	CNBK1210 CNBK1250

CNG:	CNAG_01889 CNAG_01893

CGI:	CGB_K1480C CGB_K1520W

CDEU:

CNBG_3050 CNBG_3053

CDEC:

89991729(IAS62_004958) 89991733(IAS62_004962)

CTEG:

91992086(I308_105230) 91992090(I308_105234)

CBAS:

91985349(I312_105304) 91985353(I312_105308)

CDEP:

91086736(L203_102524)

KMG:	30161548(I203_105927)

KNE:	92183370(IAR55_006112)

KDJ:	28964257(I303_100557)

KBI:	30206791(I302_103687)

KPIN:

30168861(I206_100834)

KSH:	87952674(IL334_000543)

KER:	91102818(V865_004016)

KSN:	43586209(CI109_106836)

KBO:	90013865(L199_002879)

KEP:	91091255(L201_000583)

TMS:	TREMEDRAFT_57346

TASA:

A1Q1_04691

CCAC:

CcaHIS019_0204350(ECM4)

TVS:	TRAVEDRAFT_50990 TRAVEDRAFT_66368 TRAVEDRAFT_73942

DSQ:	DICSQDRAFT_137388 DICSQDRAFT_181982

PCO:	PHACADRAFT_200431 PHACADRAFT_251136

SHS:	STEHIDRAFT_106892 STEHIDRAFT_83033

HIR:	HETIRDRAFT_107605(GST9) HETIRDRAFT_39076(GST11) HETIRDRAFT_442680(GST8)

PSQ:	PUNSTDRAFT_118707 PUNSTDRAFT_52675 PUNSTDRAFT_55793 PUNSTDRAFT_62356

ADL:	AURDEDRAFT_115811 AURDEDRAFT_115815 AURDEDRAFT_83353

FME:	FOMMEDRAFT_130383 FOMMEDRAFT_130388 FOMMEDRAFT_143667

GTR:	GLOTRDRAFT_112236 GLOTRDRAFT_120328 GLOTRDRAFT_137290 GLOTRDRAFT_37102

RSX:	RhiXN_00999

LBC:	LACBIDRAFT_179508

CCI:	CC1G_04116 CC1G_11081

ABP:	AGABI1DRAFT86711(AGABI1DRAFT_86711)

ABV:	AGABI2DRAFT137874(AGABI2DRAFT_137874)

PCUB:

JR316_0009139

MPR:	MPER_10964

MRR:	Moror_4468 Moror_4470 Moror_4473

66075259 66075261 66075262

SCM:	SCHCO_02086920(SCHCODRAFT_02086920) SCHCO_02516063(SCHCODRAFT_02516063) SCHCO_02615640(SCHCODRAFT_02615640)

CPUT:

CONPUDRAFT_60697 CONPUDRAFT_82579

SLA:	SERLADRAFT_379203

WSE:	WALSEDRAFT_31542 WALSEDRAFT_60195

WIC:	J056_002802

UMA:	UMAG_01515 UMAG_11662

PFP:	PFL1_00997

SGRA:

EX895_004260 EX895_004313

MGL:

MGL_1656

MSYM:

MSY001_2538

MJP:	85226101(ECM4_2)

MVES:

80902134(ECM4)

MLR:	MELLADRAFT_35938

RIE:	OCT59_003883

» show all

Reference

1 [PMID:16747320]

Authors

Crook EM

Title

The system dehydroascorbic acid-glutathione.

Journal

Biochem J 35:226-36 (1941)
DOI:10.1042/bj0350226

Other DBs

ExplorEnz - The Enzyme Database:

1.8.5.1

IUBMB Enzyme Nomenclature:

1.8.5.1

ExPASy - ENZYME nomenclature database:

1.8.5.1

BRENDA, the Enzyme Database:

1.8.5.1

CAS:

9026-38-4

All links

Gene (658)   
   MGENES (55)   
   RefGene (603)   
Protein sequence (2862)   
   UniProt (2769)   
   SWISS-PROT (26)   
   RefSeq(pep) (52)   
   PDBSTR (15)   
DNA sequence (159)   
   RefSeq(nuc) (60)   
   GenBank (49)   
   EMBL (50)   
3D Structure (11)   
   PDB (11)   
Protein domain (3)   
   InterPro (3)   
All databases (3693)   

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