KEGG   ENZYME: 1.8.98.3Help
Entry
EC 1.8.98.3                 Enzyme                                 

Name
sulfite reductase (coenzyme F420);
coenzyme F420-dependent sulfite reductase;
Fsr
Class
Oxidoreductases;
Acting on a sulfur group of donors;
With other, known, physiological acceptors
BRITE hierarchy
Sysname
hydrogen sulfide:coenzyme F420 oxidoreductase
Reaction(IUBMB)
hydrogen sulfide + 3 oxidized coenzyme F420 + 3 H2O = sulfite + 3 reduced coenzyme F420 [RN:R10803]
Reaction(KEGG)
Substrate
hydrogen sulfide [CPD:C00283];
oxidized coenzyme F420 [CPD:C00876];
H2O [CPD:C00001]
Product
sulfite [CPD:C00094];
reduced coenzyme F420 [CPD:C01080]
Comment
The enzyme, isolated from the archaeon Methanocaldococcus jannaschii, is involved in sulfite detoxification and assimilation.
History
EC 1.8.98.3 created 2014
Orthology
K21816  sulfite reductase (coenzyme F420)
Genes
MJA: MJ_0870
MFE: Mefer_1132
MVU: Metvu_0754
MFS: MFS40622_1290 MFS40622_1412
MIF: Metin_1351
MJH: JH146_1030
MIG: Metig_1040
MAE: Maeo_0778
MOK: Metok_0476
MTH: MTH_280
METC: MTCT_0242
MEB: Abm4_0376
MCUB: MCBB_1036
MFV: Mfer_0696
MKA: MK0799
MBU: Mbur_0619
MMET: MCMEM_1088
MMH: Mmah_0276
 » show all
Taxonomy
Reference
1  [PMID:16048999]
  Authors
Johnson EF, Mukhopadhyay B
  Title
A new type of sulfite reductase, a novel coenzyme F420-dependent enzyme, from the methanarchaeon Methanocaldococcus jannaschii.
  Journal
J Biol Chem 280:38776-86 (2005)
DOI:10.1074/jbc.M503492200
  Sequence
[mja:MJ_0870]
Reference
2  [PMID:18378657]
  Authors
Johnson EF, Mukhopadhyay B
  Title
Coenzyme F420-dependent sulfite reductase-enabled sulfite detoxification and use  of sulfite as a sole sulfur source by Methanococcus maripaludis.
  Journal
Appl Environ Microbiol 74:3591-5 (2008)
DOI:10.1128/AEM.00098-08
Other DBs
ExplorEnz - The Enzyme Database: 1.8.98.3
IUBMB Enzyme Nomenclature: 1.8.98.3
ExPASy - ENZYME nomenclature database: 1.8.98.3
BRENDA, the Enzyme Database: 1.8.98.3

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