Entry
Name
pyrogallol hydroxytransferase;
1,2,3,5-tetrahydroxybenzene hydroxyltransferase;
1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase;
1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase);
pyrogallol hydroxyltransferase;
1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase
Class
Oxidoreductases;
Other oxidoreductases;
Sole sub-subclass for oxidoreductases that do not belong in the other subclasses
BRITE hierarchy
Sysname
1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase
Reaction(IUBMB)
1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene [RN:
R04297 ]
Reaction(KEGG)
Substrate
1,2,3,5-tetrahydroxybenzene [CPD:
C03743 ];
1,2,3-trihydroxybenzene [CPD:
C01108 ]
Product
1,3,5-trihydroxybenzene [CPD:
C02183 ];
1,2,3,5-tetrahydroxybenzene [CPD:
C03743 ]
Comment
1,2,3,5-Tetrahydroxybenzene acts as a co-substrate for the conversion of pyrogallol into phloroglucinol, and for a number of similar isomerizations. The enzyme is provisionally listed here, but might be considered as the basis for a new class in the transferases, analogous to the aminotransferases.
History
EC 1.97.1.2 created 1992
Pathway
ec01120 Microbial metabolism in diverse environments
Reference
Authors
Brune A, Schink B.
Title
Pyrogallol-to-phloroglucinol conversion and other hydroxyl-transfer reactions catalyzed by cell extracts of Pelobacter acidigallici.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.97.1.2
ExPASy - ENZYME nomenclature database: 1.97.1.2
UM-BBD (Biocatalysis/Biodegradation Database): 1.97.1.2