KEGG   ENZYME: 2.1.1.119Help
Entry
EC 2.1.1.119                Enzyme                                 

Name
10-hydroxydihydrosanguinarine 10-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 10-hydroxydihydrosanguinarine = S-adenosyl-L-homocysteine + dihydrochelirubine [RN:R04707]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
10-hydroxydihydrosanguinarine [CPD:C05247]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
dihydrochelirubine [CPD:C05194]
Comment
This reaction is part of the pathway for synthesis of benzophenanthridine alkaloids in plants.
History
EC 2.1.1.119 created 1999
Pathway
ec00950  Isoquinoline alkaloid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Reference
1
  Authors
De-Eknamkul, W., Tanahashi, T. and Zenk, M.H.
  Title
Enzymic 10-hydroxylation and 10-O-methylation of dihydrosanguinarine in dihydrochelirubine formation by Eschscholtzia.
  Journal
Phytochemistry 31:2713-2717 (1992)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.119
IUBMB Enzyme Nomenclature: 2.1.1.119
ExPASy - ENZYME nomenclature database: 2.1.1.119
BRENDA, the Enzyme Database: 2.1.1.119
CAS: 144388-39-6

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