KEGG   ENZYME: 2.1.1.154Help
Entry
EC 2.1.1.154                Enzyme                                 

Name
isoliquiritigenin 2'-O-methyltransferase;
chalcone OMT;
CHMT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin [RN:R07242]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
isoliquiritigenin [CPD:C08650]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
2'-O-methylisoliquiritigenin [CPD:C15531]
Comment
Not identical to EC 2.1.1.65, licodione 2'-O-methyltransferase [2]. While EC 2.1.1.154, isoliquiritigenin 2'-O-methyltransferase can use licodione as a substrate, EC 2.1.1.65 cannot use isoliquiritigenin as a substrate.
History
EC 2.1.1.154 created 2004
Orthology
K21553  isoliquiritigenin 2'-O-methyltransferase
Genes
EGR: 104445297
GMX: 100787536 100798295 100798347 100802593
PVU: PHAVU_007G090100g PHAVU_007G091000g
VRA: 106759043 106772242 106772244
VAR: 108318701 108324723 108324724 108325719 108326037
CCAJ: 109792778 109803028
MTR: MTR_1g096310 MTR_2g055940 MTR_6g060290 MTR_7g012070
CAM: 101489515
ADU: 107470446 107491547
AIP: 107642249
LJA: Lj1g3v2994540.2(Lj1g3v2994540.2) Lj5g3v1853310.1(Lj5g3v1853310.1) Lj5g3v1853430.1(Lj5g3v1853430.1)
LANG: 109359216
 » show all
Taxonomy
Reference
1  [PMID:1731632]
  Authors
Maxwell CA, Edwards R, Dixon RA.
  Title
Identification, purification, and characterization of S-adenosyl-L-methionine: isoliquiritigenin 2'-O-methyltransferase from alfalfa (Medicago sativa L.).
  Journal
Arch Biochem Biophys 293:158-66 (1992)
DOI:10.1016/0003-9861(92)90379-B
  Sequence
Reference
2  [PMID:9055445]
  Authors
Ichimura M, Furuno T, Takahashi T, Dixon RA, Ayabe S.
  Title
Enzymic O-methylation of isoliquiritigenin and licodione in alfalfa and licorice cultures.
  Journal
Phytochemistry 44:991-5 (1997)
DOI:10.1016/S0031-9422(96)00670-X
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.154
IUBMB Enzyme Nomenclature: 2.1.1.154
ExPASy - ENZYME nomenclature database: 2.1.1.154
BRENDA, the Enzyme Database: 2.1.1.154
CAS: 139317-14-9

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