KEGG   ENZYME: 2.1.1.154
Entry
EC 2.1.1.154                Enzyme                                 
Name
isoliquiritigenin 2'-O-methyltransferase;
chalcone OMT;
CHMT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin [RN:R07242]
Reaction(KEGG)
R07242
Substrate
S-adenosyl-L-methionine [CPD:C00019];
isoliquiritigenin [CPD:C08650]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
2'-O-methylisoliquiritigenin [CPD:C15531]
Comment
Not identical to EC 2.1.1.65, licodione 2'-O-methyltransferase [2]. While EC 2.1.1.154, isoliquiritigenin 2'-O-methyltransferase can use licodione as a substrate, EC 2.1.1.65 cannot use isoliquiritigenin as a substrate.
History
EC 2.1.1.154 created 2004
Orthology
K21553  isoliquiritigenin 2'-O-methyltransferase
Genes
PVY116125315
EGR104449527
GMX100787536 100798347 100802593
GSJ114370915 114401317 114401452
PVUPHAVU_007G090100g PHAVU_007G091000g
VRA106772242 106772244
VAR108318701 108324723 108324724 108325719 108326037
VUN114190466 114190779 114192264 114192266 114192433
CCAJ109803028
APRC113871769 113871770 113871771 113871772 113871773 113873258
MTRMTR_1g096310
CAM101489515
LJALj5g3v1853310.1(Lj5g3v1853310.1) Lj5g3v1853430.1(Lj5g3v1853430.1)
ADU107491547
AIP107642249
AHF112743545 112752034 112803088
LANG109359216
QLO115963914 115965339 115965980 115966026
 » show all
Reference
1  [PMID:1731632]
  Authors
Maxwell CA, Edwards R, Dixon RA.
  Title
Identification, purification, and characterization of S-adenosyl-L-methionine: isoliquiritigenin 2'-O-methyltransferase from alfalfa (Medicago sativa L.).
  Journal
Arch Biochem Biophys 293:158-66 (1992)
DOI:10.1016/0003-9861(92)90379-B
  Sequence
Reference
2  [PMID:9055445]
  Authors
Ichimura M, Furuno T, Takahashi T, Dixon RA, Ayabe S
  Title
Enzymic O-methylation of isoliquiritigenin and licodione in alfalfa and licorice cultures.
  Journal
Phytochemistry 44:991-5 (1997)
DOI:10.1016/S0031-9422(96)00670-X
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.154
IUBMB Enzyme Nomenclature: 2.1.1.154
ExPASy - ENZYME nomenclature database: 2.1.1.154
BRENDA, the Enzyme Database: 2.1.1.154
CAS: 139317-14-9

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