KEGG   ENZYME: 2.1.1.168
Entry
EC 2.1.1.168                Enzyme                                 
Name
21S rRNA (uridine2791-2'-O)-methyltransferase;
MRM2 (gene name);
mitochondrial 21S rRNA methyltransferase;
mitochondrial rRNA MTase 2
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:21S rRNA (uridine2791-2'-O-)-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + uridine2791 in 21S rRNA = S-adenosyl-L-homocysteine + 2'-O-methyluridine2791 in 21S rRNA
Substrate
S-adenosyl-L-methionine [CPD:C00019];
uridine2791 in 21S rRNA
Product
S-adenosyl-L-homocysteine [CPD:C00021];
2'-O-methyluridine2791 in 21S rRNA
Comment
The enzyme catalyses the methylation of uridine2791 of mitochondrial 21S rRNA.
History
EC 2.1.1.168 created 2010
Orthology
K15508  21S rRNA (uridine2791-2'-O)-methyltransferase
Genes
SCE: YGL136C(MRM2)
SEUB: DI49_1839
SPAO: SPAR_G01130
AGO: AGOS_AFL117C
ERC: Ecym_2178
KLA: KLLA0_B01980g
KMX: KLMA_40559(MRM2)
LTH: KLTH0H03630g
VPO: Kpol_1002p37
ZRO: ZYRO0E07370g
CGR: 2888754(GVI51_H08855)
NCS: NCAS_0D04060(NCAS0D04060)
NDI: NDAI_0I00870(NDAI0I00870)
TPF: TPHA_0J02530(TPHA0J02530)
TBL: TBLA_0A06070(TBLA0A06070)
TGB: HG536_0E05570
TDL: TDEL_0E05470(TDEL0E05470)
KAF: KAFR_0A06980(KAFR0A06980)
KNG: KNAG_0F01850(KNAG0F01850)
ZMK: HG535_0B01070
SLUD: SCDLUD_001125
DHA: DEHA2A00902g
PIC: PICST_54885(MRM2)
PGU: PGUG_04922
SPAA: SPAPADRAFT_133465
LEL: PVL30_002372(MRM2_1)
LBG: 92207185(LODBEIA_P19890)
CAL: CAALFM_CR10260WA(CaO19.7601)
CTP: CTRG_05839
COT: CORT_0D00650
CDU: CD36_35230
CTEN: 18245469(MRM2_1)
CLU: CLUG_00829
CLUS: A9F13_10g01012
CAUR: CJI96_0002574
ASAU: 88175161(PUMCH_004099)
PPA: PAS_chr1-1_0182
PKZ: C5L36_0A06370
BNN: FOA43_001586
BBRX: BRETT_004923
OPA: HPODL_02704
NCR: NCU12112
SMP: 10802195(SMAC4_06164)
PAN: PODANSg910
PBEL: QC761_0063670(MRM2)
PPSD: QC762_402430(MRM2)
TTT: THITE_2110860
MTM: MYCTH_2307459
RTHE: 98128956(VTJ83DRAFT_7485)
MGR: MGG_04502
PPEI: PpBr36_05341
TMN: UCRPA7_2772
SSCK: SPSK_05255
FGR: FGSG_09867
FPU: FPSE_10214
FPOA: FPOAC1_002942
FVR: FVEG_02579
FOX: FOXG_05560
NHE: NECHADRAFT_41834
FKR: NCS57_00714200
TRE: TRIREDRAFT_56345
TRR: M419DRAFT_72593
MAW: 19245108(MRM2_1)
MAJ: MAA_08235
UVI: 66065465(UV8b_04687)
PLJ: 28891703(PLICBS_010252)
DCON: 63717704(DCS_05061)
VAL: VDBG_07045
VDA: VDAG_06685
CFJ: CFIO01_07045
CDET: 87950649(CDEST_14149)
SAPO: SAPIO_CDS8547
ELA: UCREL1_8974
PFY: PFICI_06430
SSL: SS1G_10584
BFU: BCIN_04g01170(Bcmrm2)
PSCO: LY89DRAFT_618377
GLZ: GLAREA_04625
ACT: ACLA_068050
NFI: NFIA_083050
AOR: AO090001000745
ANG: An02g14920
PCS: N7525_007720
PDP: PDIP_56780
TRG: TRUGW13939_06086
CIM: CIMG_07241
CPW: 9692423(MRM2)
URE: UREG_05685
ABE: ARB_02633
AJE: HCAG_02032
BGH: BDBG_09494
PNO: SNOG_02889
PTE: PTT_07944
BZE: COCCADRAFT_7764
BSC: COCSADRAFT_112979
BOR: COCMIDRAFT_166
AALT: CC77DRAFT_1098056
ADAC: 96088004(ACET3X_007682)
ZTR: MYCGRDRAFT_73148
PFJ: MYCFIDRAFT_100647
FFU: CLAFUR5_09719
NPA: UCRNP2_4269
TML: GSTUM_00005489001
SPO: 2540444(mrm2)
SOM: SOMG_00137(mrm2)
TASA: A1Q1_07548
PFP: PFL1_02317
PGR: PGTG_10173
DDI: DDB_G0271998(fsjB)
 » show all
Reference
1  [PMID:11867542]
  Authors
Pintard L, Bujnicki JM, Lapeyre B, Bonnerot C
  Title
MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase.
  Journal
EMBO J 21:1139-47 (2002)
DOI:10.1093/emboj/21.5.1139
  Sequence
[sce:YGL136C]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.168
IUBMB Enzyme Nomenclature: 2.1.1.168
ExPASy - ENZYME nomenclature database: 2.1.1.168
BRENDA, the Enzyme Database: 2.1.1.168

  All links  
Gene (31)   
   RefGene (31)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (13)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (5)   
All databases (49)   

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