Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy

S-adenosyl-L-methionine:tRNA (cytidine32/guanosine34-2'-O)-methyltransferase

S-adenosyl-L-methionine + cytidine32/guanosine34 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine32/2'-O-methylguanosine34 in tRNA

S-adenosyl-L-methionine [CPD:C00019];
cytidine32/guanosine34 in tRNA

The enzyme from Saccharomyces cerevisiae catalyses the formation of 2'-O-methylnucleotides at positions 32 and 34 of the yeast tRNAPhe, tRNATrp and, possibly, tRNALeu.

EC 2.1.1.205 created 2011

1  [PMID:11927565]

Pintard L, Lecointe F, Bujnicki JM, Bonnerot C, Grosjean H, Lapeyre B

Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.

EMBO J 21:1811-20 (2002)
DOI:10.1093/emboj/21.7.1811

[sce:YBR061C]