KEGG   ENZYME: 2.1.1.21Help
Entry
EC 2.1.1.21                 Enzyme                                 

Name
methylamine---glutamate N-methyltransferase;
N-methylglutamate synthase;
methylamine-glutamate methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
methylamine:L-glutamate N-methyltransferase
Reaction(IUBMB)
methylamine + L-glutamate = NH3 + N-methyl-L-glutamate [RN:R01586]
Reaction(KEGG)
Substrate
methylamine [CPD:C00218];
L-glutamate [CPD:C00025]
Product
NH3 [CPD:C00014];
N-methyl-L-glutamate [CPD:C01046]
History
EC 2.1.1.21 created 1972
Pathway
ec00680  Methane metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K22081  methylamine---glutamate N-methyltransferase subunit A
K22082  methylamine---glutamate N-methyltransferase subunit B
K22083  methylamine---glutamate N-methyltransferase subunit C
Genes
PMY: Pmen_3465 Pmen_3466 Pmen_3467
PRE: PCA10_14290 PCA10_14300 PCA10_14310
PCQ: PcP3B5_34400(gltA_2) PcP3B5_34410 PcP3B5_34420(purF_2)
PPG: PputGB1_2248 PputGB1_2249 PputGB1_2250
PPT: PPS_3152 PPS_3153 PPS_3154
PPX: T1E_2051 T1E_2052(glxC) T1E_2053(glxD)
PPUH: B479_15655 B479_15660 B479_15665
PPUT: L483_16930 L483_16935 L483_16940 L483_19175 L483_19180 L483_19185
PPUN: PP4_21640 PP4_21650 PP4_21660
PPUD: DW66_3424 DW66_3425 DW66_3426
REH: H16_B2192(glxb) H16_B2193(glxC) H16_B2194(gltB2)
AZO: azo3011(glxB) azo3012(glxC) azo3013(glxD)
AMIH: CO731_05431(glmS_2) CO731_05432 CO731_05433(gltA_2)
SME: SMc02610(glxB) SMc02611(glxC) SMc02612(glxD)
SMX: SM11_chr3558(glxB) SM11_chr3559(glxC) SM11_chr3560(glxD)
SMI: BN406_03221(glxB) BN406_03222(glxC) BN406_03223(glxD)
SMEL: SM2011_c02610(glxB) SM2011_c02611(glxC) SM2011_c02612(glxD)
RHI: NGR_c14380(glxB) NGR_c14390(glxC) NGR_c14400(glxD)
SFH: SFHH103_06334(glxD) SFHH103_06335(glxC) SFHH103_06336(glxB)
ATU: Atu4227(purF) Atu4228(fwdC) Atu4229(gltB)
ARA: Arad_8362(glxB) Arad_8364(glxC) Arad_8365(glxD)
ATF: Ach5_36160 Ach5_36170(fwdC) Ach5_36180(purF)
AVI: Avi_5749(purF) Avi_5750(fwdC) Avi_5751(gltB)
RET: RHE_PE00419(glxD) RHE_PE00420(glxC) RHE_PE00421(glxB)
RLE: pRL110555(glxD) pRL110556(glxC) pRL110557(glxB)
RHN: AMJ98_PD00426(glxD) AMJ98_PD00427(glxC) AMJ98_PD00428(glxB)
RPHA: AMC79_PB00340(glxD) AMC79_PB00341(glxC) AMC79_PB00342(glxB)
RHX: AMK02_PE00433(glxD) AMK02_PE00434(glxC) AMK02_PE00435(glxB)
RHK: Kim5_PB00402(glxD) Kim5_PB00403(glxC) Kim5_PB00404(glxB)
MAQU: Maq22A_c07635(gltB) Maq22A_c07640(gltB) Maq22A_c07645(gltB)
HMC: HYPMC_4363(mgsA) HYPMC_4364(mgsB) HYPMC_4365(mgsC)
HDI: HDIA_3399(gltA_2) HDIA_3400 HDIA_3401(glmS)
PAMN: pAMV1p0106(mgsA) pAMV1p0107(mgsB) pAMV1p0108(mgsC)
PTP: RCA23_c23610(glxB) RCA23_c23620(glxC) RCA23_c23630(glxD)
KEU: S101446_00795(purF) S101446_00796(fwdC) S101446_00797(gltB)
PUB: SAR11_1308 SAR11_1313(glxB) SAR11_1314(glxC) SAR11_1315(glxD)
FAL: FRAAL1888 FRAAL1890(glxD)
 » show all
Taxonomy
Reference
1  [PMID:5905132]
  Authors
Shaw WV, Tsai L, Stadtman ER.
  Title
The enzymatic synthesis of N-methylglutamic acid.
  Journal
J Biol Chem 241:935-45 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.21
IUBMB Enzyme Nomenclature: 2.1.1.21
ExPASy - ENZYME nomenclature database: 2.1.1.21
BRENDA, the Enzyme Database: 2.1.1.21
CAS: 9045-32-3

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