KEGG   ENZYME: 2.1.1.21Help
Entry
EC 2.1.1.21                 Enzyme                                 

Name
methylamine---glutamate N-methyltransferase;
N-methylglutamate synthase;
methylamine-glutamate methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
methylamine:L-glutamate N-methyltransferase
Reaction(IUBMB)
methylamine + L-glutamate = NH3 + N-methyl-L-glutamate [RN:R01586]
Reaction(KEGG)
Substrate
methylamine [CPD:C00218];
L-glutamate [CPD:C00025]
Product
NH3 [CPD:C00014];
N-methyl-L-glutamate [CPD:C01046]
History
EC 2.1.1.21 created 1972
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K22081  methylamine---glutamate N-methyltransferase subunit A
K22082  methylamine---glutamate N-methyltransferase subunit B
K22083  methylamine---glutamate N-methyltransferase subunit C
Genes
VPB: VPBB_A0706
VPK: M636_03290
VPF: M634_21775
VPH: VPUCM_20666
VAG: N646_4163
VEX: VEA_000267
VDB: AL552_06545
VHR: AL538_25000
VNA: PN96_19960
VOW: A9237_21850
VSP: VS_2138
VTA: A2453
PCQ: PcP3B5_34400(gltA_2) PcP3B5_34410 PcP3B5_34420(purF_2)
PPX: T1E_2051 T1E_2052(glxC) T1E_2053(glxD)
SLO: Shew_2984
SSE: Ssed_3552
SPL: Spea_3227
SHL: Shal_3299
SWD: Swoo_3007
SWP: swp_0971
SVO: SVI_3467
SPSW: Sps_04476
CPS: CPS_1903
PSEN: PNC201_20860(gltB2)
FBL: Fbal_0057
NWA: Nwat_2963
TEE: Tel_14685
TKM: TK90_1518
TNI: TVNIR_1529(gltB_[C])
TVR: TVD_07390
REH: H16_B2192(glxb) H16_B2193(glxC) H16_B2194(gltB2)
AZO: azo3011(glxB) azo3012(glxC) azo3013(glxD)
DDS: Ddes_1157
DPS: DP0505
AMIH: CO731_05431(glmS_2) CO731_05432 CO731_05433(gltA_2)
RBS: RHODOSMS8_03430(gltA)
SME: SMc02610(glxB) SMc02611(glxC) SMc02612(glxD)
SMX: SM11_chr3558(glxB) SM11_chr3559(glxC) SM11_chr3560(glxD)
SMI: BN406_03221(glxB) BN406_03222(glxC) BN406_03223(glxD)
SMEL: SM2011_c02610(glxB) SM2011_c02611(glxC) SM2011_c02612(glxD)
RHI: NGR_c14380(glxB) NGR_c14390(glxC) NGR_c14400(glxD)
SFH: SFHH103_06334(glxD) SFHH103_06335(glxC) SFHH103_06336(glxB)
ATU: Atu4227(purF) Atu4228(fwdC) Atu4229(gltB)
ARA: Arad_8362(glxB) Arad_8364(glxC) Arad_8365(glxD)
ATF: Ach5_36160 Ach5_36170(fwdC) Ach5_36180(purF)
AVI: Avi_5749(purF) Avi_5750(fwdC) Avi_5751(gltB)
RET: RHE_PE00419(glxD) RHE_PE00420(glxC) RHE_PE00421(glxB)
RLE: pRL110555(glxD) pRL110556(glxC) pRL110557(glxB)
RHN: AMJ98_PD00426(glxD) AMJ98_PD00427(glxC) AMJ98_PD00428(glxB)
RPHA: AMC79_PB00340(glxD) AMC79_PB00341(glxC) AMC79_PB00342(glxB)
RHX: AMK02_PE00433(glxD) AMK02_PE00434(glxC) AMK02_PE00435(glxB)
RHK: Kim5_PB00402(glxD) Kim5_PB00403(glxC) Kim5_PB00404(glxB)
REZ: AMJ99_PC00427(glxD) AMJ99_PC00428(glxC) AMJ99_PC00429(glxB)
MAQU: Maq22A_c07635(gltB) Maq22A_c07640(gltB) Maq22A_c07645(gltB)
BBAR: RHAL1_02576(mgsC) RHAL1_02577(mgsB) RHAL1_02578(glxB)
HMC: HYPMC_4363(mgsA) HYPMC_4364(mgsB) HYPMC_4365(mgsC)
PLEO: OHA_1_03150(glmS_2) OHA_1_03151 OHA_1_03152(gltA_2)
HDI: HDIA_3399(gltA_2) HDIA_3400 HDIA_3401(glmS)
RUT: FIU92_04950(purF1) FIU92_04955 FIU92_04960(gltA1)
JAN: Jann_3121
PAMN: pAMV1p0106(mgsA) pAMV1p0107(mgsB) pAMV1p0108(mgsC)
PSF: PSE_1109
PTP: RCA23_c23610(glxB) RCA23_c23620(glxC) RCA23_c23630(glxD)
LABT: FIU93_11205(gltA1)
KEU: S101446_00795(purF) S101446_00796(fwdC) S101446_00797(gltB)
KSC: CD178_01526(purF_2) CD178_01527 CD178_01528(gltA)
BMEG: BG04_5799
OIH: OB0697
AAD: TC41_2039
BPRO: PMF13cell1_01335(gltA_1)
STH: STH930
DSY: DSY4044
AWO: Awo_c07180(glxB) Awo_c07190(glxC) Awo_c07200(glxD)
TMR: Tmar_0774
MTHO: MOTHE_c20620(gltS)
MTHZ: MOTHA_c21400(gltS)
CAD: Curi_c05380(gltB1) Curi_c06530(gltB2)
MANA: MAMMFC1_02802(gltB)
STED: SPTER_37580(fni_2) SPTER_43730
PFAC: PFJ30894_01965(gltA)
MHAS: MHAS_03923(glmS_2) MHAS_03924 MHAS_03925(gltA)
MCHE: BB28_24180
MSTE: MSTE_04897
ASD: AS9A_2461
GRU: GCWB2_23575(gltA2) GCWB2_23580 GCWB2_23585(glmS2)
GOM: D7316_03131(gltB_2) D7316_03132 D7316_03133(glmS_2)
SHY: SHJG_1666
SFK: KY5_0482c
SRJ: SRO_1557
NAL: B005_1644
FAL: FRAAL1888 FRAAL1889(glxC) FRAAL1890(glxD)
AOI: AORI_3157
RBA: RB5439(fwdC)
RUL: UC8_20200
FLM: MY04_2505
CBAT: M666_04210
CPC: Cpar_0213
CLI: Clim_1229
PPH: Ppha_0954
PAA: Paes_2083
CTS: Ctha_0161
MMD: GYY_04030
METE: tca_00174 tca_00176(gltA_2) tca_01614(gltA_3)
MEB: Abm4_0994(gltA) Abm4_0995(gltB) Abm4_0996
MMIL: sm9_1163 sm9_1451 sm9_1452(gltB) sm9_1454(gltA)
MOL: YLM1_0399
MFC: BRM9_0648 BRM9_0649(gltB1) BRM9_0652(gltA1) BRM9_0966(gltB2) BRM9_1602(gltA3)
MCUB: MCBB_0615 MCBB_1650 MCBB_1651(glxC) MCBB_1653(glxD1) MCBB_2012(fwdC3)
MKA: MK1064(gltB_3)
MARC: AR505_1047
MMET: MCMEM_0725
MMH: Mmah_1580
MPI: Mpet_1731
MPL: Mpal_1225
IHO: Igni_0407
PIS: Pisl_0142
TNE: Tneu_0458
CMA: Cmaq_0063
TTN: TTX_0637(gltB)
TAA: NMY3_03179(gltB) NMY3_03180(glmS_1) NMY3_03182(gltA)
 » show all
Taxonomy
Reference
1  [PMID:5905132]
  Authors
Shaw WV, Tsai L, Stadtman ER.
  Title
The enzymatic synthesis of N-methylglutamic acid.
  Journal
J Biol Chem 241:935-45 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.21
IUBMB Enzyme Nomenclature: 2.1.1.21
ExPASy - ENZYME nomenclature database: 2.1.1.21
BRENDA, the Enzyme Database: 2.1.1.21
CAS: 9045-32-3

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