KEGG ENZYME: 2.1.1.210

ENZYME: 2.1.1.210

Entry

EC 2.1.1.210                Enzyme

Name

demethylspheroidene O-methyltransferase;
1-hydroxycarotenoid O-methylase;
1-hydroxycarotenoid methylase;
1-HO-carotenoid methylase;
CrtF

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + demethylspheroidene = S-adenosyl-L-homocysteine + spheroidene [RN:R07535]

Reaction(KEGG)

R07535;
(other) R07521 R07524 R07527 R07529 R07533 R12753

Substrate

S-adenosyl-L-methionine [CPD:C00019];
demethylspheroidene [CPD:C15898]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
spheroidene [CPD:C15900]

Comment

In Rhodopseudomonas capsulata and Rubrivivax gelatinosus the enzyme is involved in biosynthesis of spheroidene [1,2,3]. In Rubrivivax gelatinosus the enzyme also catalyses the methylation of demethylspirilloxanthin to spirilloxanthin and the methylation of 3,4-didehydrorhodopin to anhydrorhodovibrin [2].

History

EC 2.1.1.210 created 2011

Pathway

ec00906

Carotenoid biosynthesis

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K09846

demethylspheroidene O-methyltransferase

Genes

ALV:	Alvin_2564

ATEP:

Atep_25170

TVI:	Thivi_2013

TMB:	Thimo_3007

MPUR:

MARPU_13360

TSY:	THSYN_31020

TTP:	E6P07_01730

THIP:

N838_12385

CJAP:

GWK36_12650

THIM:

KFB96_13110 KFB96_13150

TBOG:

LT988_08915

HHA:

Hhal_1612

HHC:	M911_10360

EBS:	ECTOBSL9_3048

PDQ:	CL55_00013610

PANI:

DCO16_03470

PCOS:

C2747_06965

RAC:	RA876_05990

LIM:	L103DPR2_00970(crtF)

LIH:	L63ED372_00626(crtF)

HYR:	BSY239_1383

HCZ:	G9Q37_00120

METP:

C1M51_03585

RGE:	RGE_33720(crtF)

RBN:	RBXJA2T_09432

RDP:	RD2015_1035

ROI:	N4261_01195

ATER:

MW290_02530

METR:

BSY238_2446

BEB:	AEM42_07465

RPOD:

E0E05_11780

AGC:	BSY240_3670

ABAW:

D5400_04840

PDES:

FE840_002315

BRA:	BRADO1616(crtF)

BBT:	BBta_6439(crtF)

BRS:	S23_19160(crtF)

AOL:

S58_59200

BRO:	BRAD285_5783(crtF)

BRQ:	CIT40_23950

BGZ:	XH91_02635

BBET:

F8237_24665

RPA:	RPA1520(crtF)

RPB:

RPB_4003

RPC:

RPC_1291

RPD:

RPD_3758

RPE:

RPE_1325

RPT:

Rpal_1708

RPX:	Rpdx1_4000

BOS:	BSY19_4057

MEA:	Mex_1p2925(crtF)

MDI:	METDI3494(crtF)

MEX:

Mext_2728

MCH:

Mchl_2955

MPO:

Mpop_2850

MZA:	B2G69_21180

MRD:	Mrad2831_2820

MET:

M446_3695

MOR:

MOC_3185

META:

Y590_13130

MAQU:

Maq22A_1p32535

MPHY:

MCBMB27_02261

MEE:	DA075_03950

METD:

C0214_15295

METX:

A3862_17690

METS:

DK389_31445

METI:

DK427_17905

MMES:

MMSR116_13605

MTEA:

DK419_04910

MIND:

mvi_08960

MOG:	MMB17_23895

MTAD:

M6G65_16635

MSL:

Msil_2050

BBAR:

RHAL1_03016(crtF)

RVA:

Rvan_0208

MSC:

BN69_3625

MBRY:

B1812_02310

MROS:

EHO51_05530 EHO51_17025

MHEY:

H2LOC_006870

MPAR:

F7D14_00815

MTW:	CQW49_13335

CMET:

K6K41_01665

AUZ:	Sa4125_27770

AUB:	LXB15_06390

BSB:	Bresu_3047

BRL:	BZG35_15465

RUT:	FIU92_10165(crtF)

JAN:	Jann_0181(crtF)

RDE:	RD1_0113(crtF)

RLI:	RLO149_p940140(crtF)

RPON:

G3256_18650

DSH:	Dshi_3515(crtF)

RED:	roselon_01076

SUAM:

BOO69_19420

TOM:	BWR18_20230

RMM:	ROSMUCSMR3_00907(crtF)

ROK:	RAK1035_3776

RID:	RIdsm_01753(crtF_1)

ROM:	EI983_05430

ROH:	FIU89_14245(crtF)

THAA:

CFI11_23540

MARU:

FIU81_13870(crtF)

ROT:	FIV09_18060(crtF2)

RMH:	LVO79_17410

MALU:

KU6B_16410(crtF)

RSP:	RSP_0264(crtF)

RSH:	Rsph17029_1908

RSQ:	Rsph17025_2038

RSK:	RSKD131_1591

CAZT:

LV780_09085

RCP:	RCAP_rcc00685(crtF)

RBL:	B6K69_00180

PTP:	RCA23_c29600(crtF)

RSU:

NHU_04285

RHM:	B5V46_17495

RHC:

RGUI_1963

LVS:	LOKVESSMR4R_03677(crtF)

RBG:	BG454_03025

GEH:	HYN69_05515

TAW:	EI545_18935

POZ:	I0K15_00020

NSM:	JO391_16455

FAQ:	G5B39_11890

HBC:	AEM38_14595

NOT:	C7W88_00470

NGF:	FRF71_09135

NOG:	GKE62_08425

SPHI:

TS85_22895

SSAN:

NX02_18460

SCHY:

GVO57_11640

SGLC:

M1K48_13815

SQO:	NMP03_02110

SRAD:

LLW23_12135

CIJ:	WG74_05035

BLAS:

BSY18_3553

BFW:	B5J99_08560

PALG:

HFP57_06960

PARJ:

J4G78_07545

SAND:

H3309_05740

POQ:	KZX46_18715

PMEA:

KTC28_17025

ALH:	G6N82_11420

ELQ:	Ga0102493_111840

ERK:	CD351_13860

ERF:	FIU90_13820(crtF)

PNS:	A9D12_01280

PORL:

BG023_112668

POT:	E2E27_07345

AMV:	ACMV_18810(crtF)

SRF:	LHU95_13845

RAP:	RHOA_2426(crtF)

NCB:	C0V82_18175

SKT:	IGS68_17125

SMUC:

JL100_008910

SROE:

JL101_015305

RRU:

Rru_A2982

RRF:

F11_15275

RCE:	RC1_2092(crtF)

ELIO:

KO353_03085

GPH:	GEMMAAP_06530

GGR:	HKW67_08755

NFT:	FBF37_02080

» show all

Reference

1 [PMID:12770713]

Authors

Badenhop F, Steiger S, Sandmann M, Sandmann G

Title

Expression and biochemical characterization of the 1-HO-carotenoid methylase CrtF from Rhodobacter capsulatus.

Journal

FEMS Microbiol Lett 222:237-42 (2003)
DOI:10.1016/S0378-1097(03)00302-1

Sequence

[rcp:RCAP_rcc00685]

Reference

2 [PMID:12664193]

Authors

Pinta V, Ouchane S, Picaud M, Takaichi S, Astier C, Reiss-Husson F.

Title

Characterization of unusual hydroxy- and ketocarotenoids in Rubrivivax gelatinosus: involvement of enzyme CrtF or CrtA.

Journal

Arch Microbiol 179:354-62 (2003)
DOI:10.1007/s00203-003-0538-3

Sequence

[rge:RGE_33720]

Reference

3 [PMID:7358679]

Authors

Scolnik PA, Walker MA, Marrs BL

Title

Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata.

Journal

J Biol Chem 255:2427-32 (1980)

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.210

IUBMB Enzyme Nomenclature:

2.1.1.210

ExPASy - ENZYME nomenclature database:

2.1.1.210

BRENDA, the Enzyme Database:

2.1.1.210

DBGET integrated database retrieval system