KEGG ENZYME: 2.1.1.229

ENZYME: 2.1.1.229

Entry

EC 2.1.1.229                Enzyme

Name

tRNA (carboxymethyluridine34-5-O)-methyltransferase;
ALKBH8;
ABH8;
Trm9;
tRNA methyltransferase 9

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:tRNA (carboxymethyluridine34-5-O)-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + carboxymethyluridine34 in tRNA = S-adenosyl-L-homocysteine + 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA

Substrate

S-adenosyl-L-methionine [CPD:C00019];
carboxymethyluridine34 in tRNA

Product

S-adenosyl-L-homocysteine [CPD:C00021];
5-(2-methoxy-2-oxoethyl)uridine34 in tRNA

Comment

The enzyme catalyses the posttranslational modification of uridine residues at the wobble position 34 of the anticodon loop of tRNA.

History

EC 2.1.1.229 created 2011

Orthology

K10770

alkylated DNA repair protein alkB homolog 8

K15444

tRNA (uracil-5-)-methyltransferase TRM9

Genes

HSA:	91801(ALKBH8)

PTR:	466772(ALKBH8)

PPS:	100986393(ALKBH8)

GGO:	101146805(ALKBH8)

PON:	100443674(ALKBH8)

NLE:	100593027(ALKBH8)

HMH:	116476886(ALKBH8)

MCC:	706917(ALKBH8)

MCF:	102129238(ALKBH8)

MTHB:

126936203

MNI:	105493666(ALKBH8)

CSAB:

103248392(ALKBH8)

CATY:

105588740(ALKBH8)

PANU:

101015427(ALKBH8)

TGE:	112606357(ALKBH8)

MLEU:

105543021(ALKBH8)

RRO:	104660492(ALKBH8)

RBB:	108517385(ALKBH8)

TFN:	117080097(ALKBH8)

PTEH:

111540095(ALKBH8)

CANG:

105500968(ALKBH8)

CJC:	100388487(ALKBH8)

SBQ:	101044794(ALKBH8)

CIMI:

108316903(ALKBH8)

CSYR:

103255250(ALKBH8)

MMUR:

105876106(ALKBH8)

LCAT:

123641749(ALKBH8)

PCOQ:

105822177(ALKBH8)

OGA:	100949105(ALKBH8)

MMU:	67667(Alkbh8)

MCAL:

110288481

MPAH:

110327860(Alkbh8)

RNO:	366783(Alkbh8)

MCOC:

116074214(Alkbh8)

ANU:	117699939(Alkbh8)

MUN:	110564373(Alkbh8)

CGE:	100760738(Alkbh8)

MAUA:

101837993(Alkbh8)

PROB:

127217565(Alkbh8)

PLEU:

114688416 114709267(Alkbh8)

MORG:

121432447(Alkbh8)

MFOT:

126491154

AAMP:

119810509(Alkbh8)

NGI:	103731325(Alkbh8)

HGL:	101705703(Alkbh8)

CPOC:

100714624(Alkbh8)

CCAN:

109700254(Alkbh8)

DORD:

105980594(Alkbh8)

DSP:	122104185(Alkbh8)

NCAR:

124958740

OCU:

100355593

OPI:	101531657(ALKBH8)

TUP:	102497943(ALKBH8)

CFA:	489424(ALKBH8)

CLUD:

112671411(ALKBH8)

VVP:	112925952(ALKBH8)

VLG:	121499793(ALKBH8)

AML:	100466448(ALKBH8)

UMR:	103662428(ALKBH8)

UAH:	113260110(ALKBH8)

UAR:	123792522(ALKBH8)

ELK:

111153767

LLV:

125079063

MPUF:

101678514(ALKBH8)

NVS:	122912234(ALKBH8)

ORO:	101375464(ALKBH8)

EJU:	114211436(ALKBH8)

ZCA:	113915239(ALKBH8)

MLX:	118013179(ALKBH8)

NSU:	110586392(ALKBH8)

LWW:	102743430(ALKBH8)

FCA:	101099745(ALKBH8)

PYU:	121035340(ALKBH8)

PBG:	122482911(ALKBH8)

LRUF:

124505428

PTG:	102961068(ALKBH8)

PPAD:

109278709(ALKBH8)

PUC:

125915511

AJU:	106983930(ALKBH8)

HHV:	120224567(ALKBH8)

BTA:	781788(ALKBH8)

BOM:

102284430

BIU:	109569852(ALKBH8)

BBUB:

102389868(ALKBH8)

BBIS:

105005067(ALKBH8)

CHX:	102188424(ALKBH8)

OAS:	101104088(ALKBH8)

ODA:	120876203(ALKBH8)

CCAD:

122449538(ALKBH8)

SSC:	100626321(ALKBH8)

CBAI:

105069856(ALKBH8)

VPC:	102534148(ALKBH8)

BACU:

102999435 103003035(ALKBH8)

LVE:	103088459(ALKBH8)

OOR:	101276479(ALKBH8)

DLE:	111170794(ALKBH8)

PCAD:

102992533(ALKBH8)

PSIU:

116758771(ALKBH8)

ECB:	100061658(ALKBH8)

EPZ:	103564993(ALKBH8)

EAI:	106843661(ALKBH8)

MYB:	102256283(ALKBH8)

MYD:	102766171(ALKBH8)

MMYO:

118664402(ALKBH8)

MLF:

102428819

MNA:	107532924(ALKBH8)

PKL:	118713195(ALKBH8)

HAI:	109371436(ALKBH8)

DRO:	112314395(ALKBH8)

SHON:

118988249(ALKBH8)

AJM:	119043622(ALKBH8)

PDIC:

114500585(ALKBH8)

PHAS:

123819521(ALKBH8)

MMF:	118627598(ALKBH8)

RFQ:	117031285(ALKBH8)

PGIG:

120607115

PVP:	105297453(ALKBH8)

RAY:	107507116 107507126 107509190 107509193 107509252 107509763 107510156 107510406 107510426 107510977 107518695(ALKBH8)

MJV:	108394639(ALKBH8)

TOD:	119240896(ALKBH8)

SARA:

101551643(ALKBH8)

LAV:	100659555(ALKBH8)

TMU:

101360861

ETF:	101650677(ALKBH8)

DNM:	101423542(ALKBH8)

MDO:	100032528(ALKBH8)

GAS:	123241405(ALKBH8)

SHR:	100925951(ALKBH8)

AFZ:

127554949

PCW:	110215012(ALKBH8)

OAA:	100077668(ALKBH8)

GGA:	418972(ALKBH8)

PCOC:

116237191(ALKBH8)

MGP:	104909226(ALKBH8)

CJO:	107308365(ALKBH8)

NMEL:

110389669(ALKBH8)

APLA:

101804846(ALKBH8)

ACYG:

106047551(ALKBH8)

AFUL:

116494870(ALKBH8)

TGU:	100232062(ALKBH8)

LSR:	110470029(ALKBH8)

SCAN:

103827292(ALKBH8)

PMOA:

120506756(ALKBH8)

OTC:	121341289(ALKBH8)

PRUF:

121364281(ALKBH8)

GFR:	102044005(ALKBH8)

FAB:	101811495(ALKBH8)

PHI:	102113659(ALKBH8)

PMAJ:

107206743(ALKBH8)

CCAE:

111924140(ALKBH8)

CCW:	104690049(ALKBH8)

CBRC:

103612470(ALKBH8)

ETL:	114066021(ALKBH8)

ZAB:	102066464(ALKBH8)

ACHL:

103797258(ALKBH8)

SVG:	106854028(ALKBH8)

FPG:	101915946(ALKBH8)

FCH:	102058925(ALKBH8)

CLV:	102086962(ALKBH8)

EGZ:	104130053(ALKBH8)

NNI:	104023058(ALKBH8)

PCAO:

104046132(ALKBH8)

ACUN:

113483734(ALKBH8)

TALA:

104360765(ALKBH8)

PADL:

103926406(ALKBH8)

AFOR:

103897003(ALKBH8)

ACHC:

115353413(ALKBH8)

HLE:	104828438(ALKBH8)

AGEN:

126048469

GCL:

127027111

CCRI:

104166435(ALKBH8)

CSTI:

104557344(ALKBH8)

EHS:	104510097(ALKBH8)

CMAC:

104485784(ALKBH8)

MUI:	104548773(ALKBH8)

GSTE:

104257148(ALKBH8)

LDI:	104339971(ALKBH8)

MNB:	103773079(ALKBH8)

OHA:	104333043(ALKBH8)

NNT:	104409818(ALKBH8)

SHAB:

115604568(ALKBH8)

DPUB:

104306316(ALKBH8)

PGUU:

104471734

ACAR:

104517903(ALKBH8)

CPEA:

104390282(ALKBH8)

AVIT:

104267087

CVF:	104291651(ALKBH8)

CUCA:

104055340(ALKBH8)

BRHI:

104495824(ALKBH8)

AAM:	106493489(ALKBH8)

AROW:

112967798(ALKBH8)

NPD:	112943782(ALKBH8)

TGT:	104577075(ALKBH8)

DNE:	112983215(ALKBH8)

ASN:	102382297(ALKBH8)

AMJ:	102561181(ALKBH8)

CPOO:

109306711

GGN:	109303199(ALKBH8)

PSS:	102443978(ALKBH8)

CMY:	102932808(ALKBH8)

CPIC:

101943831(ALKBH8)

TST:	117871156(ALKBH8)

CABI:

116830992(ALKBH8)

MRV:	120368925(ALKBH8)

ACS:	100555791(alkbh8)

PVT:	110084096(ALKBH8)

SUND:

121926961(ALKBH8)

PBI:	103048090(ALKBH8)

PMUR:

107297397(ALKBH8)

CTIG:

120298403(ALKBH8)

TSR:	106548783(ALKBH8)

PGUT:

117661013(ALKBH8)

VKO:	123029339(ALKBH8)

PMUA:

114595676(ALKBH8)

ZVI:	118085207(ALKBH8)

GJA:	107118531(ALKBH8)

STOW:

125432118(ALKBH8)

XLA:	108709989(alkbh8.S)

XTR:	550051(alkbh8)

NPR:	108796088(ALKBH8)

RTEM:

120929055(ALKBH8)

BBUF:

120996381(ALKBH8)

BGAR:

122931960(ALKBH8)

DRE:	556362(alkbh8)

SRX:

107719115

SANH:

107666883(alkbh8) 107686611

SGH:	107600490(alkbh8)

CCAR:

109064512(alkbh8)

CAUA:

113115891(alkbh8)

CGIB:

127975473

PPRM:

120462188(alkbh8)

MAMB:

125243208(alkbh8)

CIDE:

127496837

MASI:

127453454

IPU:	108256248(alkbh8)

PHYP:

113524784(alkbh8)

SMEO:

124403779(alkbh8)

TFD:	113651835(alkbh8)

AMEX:

103028213(alkbh8)

EEE:	113574394(alkbh8)

TRU:	101067875(alkbh8)

TNG:	GSTEN00019484G001

LCO:	104928517(alkbh8)

NCC:	104945138(alkbh8)

CGOB:

115017732(alkbh8)

ELY:	117259312(alkbh8)

EFO:	125889326(alkbh8)

PLEP:

121943420(alkbh8)

SLUC:

116048258(alkbh8)

ECRA:

117942275(alkbh8)

ESP:	116686918(alkbh8)

PFLV:

114552382(alkbh8)

GAT:	120828245(alkbh8)

PPUG:

119210322(alkbh8)

MSAM:

119882861(alkbh8)

CUD:	121515512(alkbh8)

ALAT:

119011742(alkbh8)

MZE:	101470566(alkbh8)

ONL:	100699460(alkbh8)

OAU:	116322931(alkbh8)

OLA:	101169473(alkbh8)

OML:	112149580(alkbh8)

XMA:	102220910(alkbh8)

XCO:	114133629(alkbh8)

XHE:	116708247(alkbh8)

PRET:

103474500(alkbh8)

PFOR:

103145555(alkbh8)

PLAI:

106955683(alkbh8)

PMEI:

106921346(alkbh8)

GAF:	122832979(alkbh8)

CVG:	107093948(alkbh8)

CTUL:

119798305(alkbh8)

GMU:	124883560(alkbh8)

NFU:	107380437(alkbh8)

KMR:	108244647(alkbh8)

ALIM:

106521472(alkbh8)

NWH:	119411519(alkbh8)

AOCE:

111580971(alkbh8)

MCEP:

125013995(alkbh8)

CSEM:

103378521(alkbh8)

POV:	109629958(alkbh8)

SSEN:

122774032(alkbh8)

HHIP:

117773388(alkbh8)

HSP:	118106575(alkbh8)

LCF:

108890870

SDU:	111224087(alkbh8)

SLAL:

111651811(alkbh8)

XGL:	120792522(alkbh8)

HCQ:	109525529(alkbh8)

SSCV:

125971828

BPEC:

110174300(alkbh8)

MALB:

109971623(alkbh8)

BSPL:

114868110(alkbh8)

SASA:

100195302(alkbh8)

STRU:

115206574(alkbh8)

OTW:	112267471(alkbh8)

OMY:	110503172(alkbh8)

OGO:	124006257(alkbh8)

ONE:	115124883(alkbh8)

SALP:

111959864(alkbh8)

SNH:	120028830(alkbh8)

CCLU:

121567795(alkbh8)

ELS:	105024079(alkbh8)

SFM:	108924659(alkbh8)

PKI:	111833772(alkbh8)

AANG:

118208820(alkbh8)

LOC:	102685793(alkbh8)

PSPA:

121302710(alkbh8)

ARUT:

117406004 117973055

PSEX:

120523166(alkbh8)

LCM:	102356130(ALKBH8)

CMK:	103185771(alkbh8)

RTP:	109920145 109927218(alkbh8)

BFO:

118419193

BBEL:

109477625

CIN:

100183670

SCLV:

120327845

SPU:	580052 592985

APLC:

110977185

AJC:

117103591

SKO:

100369536

DME:	Dmel_CG17807(CG17807)

DER:

6546676

DSE:

6615554

DSI:	Dsimw501_GD25121(Dsim_GD25121)

DYA:	Dyak_GE11857

DAN:

6495852

DSR:

110175979

DPO:

4804218

DPE:

6590607

DMN:

108159422

DWI:

6646268

DGR:

6560552

DMO:	Dmoj_GI20008

DAZ:

108617529

DNV:

108654484

DHE:

111593917

DVI:

6625492

CCAT:

101461239

BOD:

106627119

RZE:

108381707

MDE:

101894009

SCAC:

106091948

LCQ:

111687412

LSQ:

119615921

HIS:

119656141

AGA:	AgaP_AGAP011900

ACOZ:

120958253

AARA:

120903628

ASTE:

118508065

AAG:

5567453

AALB:

109410742

CQU:	CpipJ_CPIJ001243

CPII:

120428804

CNS:

116340256

BCOO:

119076671

AME:

411649

ACER:

107997909

ALAB:

122715077

BIM:

100746842

BBIF:

117207027

BVK:

117231139

BVAN:

117154245

BTER:

100650876

BPYO:

122565675

CCAL:

108625041

OBB:

114874081

MGEN:

117218293

NMEA:

116429323

CGIG:

122403537

SOC:

105193071

MPHA:

105839545

AEC:

105144255

ACEP:

105619235

PBAR:

105433077

VEM:

105570642

HST:

105182053

DQU:

106743531

CFO:

105251336

FEX:

115236756

LHU:

105668425

PGC:

109857915

OBO:

105277869

PCF:

106785310

PFUC:

122518609

VPS:

122635559

NVI:

100122369

CSOL:

105365426

TPRE:

106654162 106654164

MDL:

103574650

CGLO:

123262437

FAS:

105271497

DAM:

107047868

AGIF:

122851861

CINS:

118065223

LHT:

122509640

CCIN:

107268536

TCA:

663807

DPA:

109542362

SOY:

115881620

ATD:

109601077

CSET:

123309649

AGB:

108912065

LDC:

111508982

NVL:

108562219

APLN:

108738031

PPYR:

116168027

OTU:

111415793

BMOR:

101736667

BMAN:

114239741

MSEX:

115452927

DPL:	KGM_211918

BANY:

112053482

NIQ:

126781671

PMAC:

106709549

PPOT:

106105028

PXU:

106123388

PRAP:

110998356

PBX:

123712494

PNAP:

125057898

ZCE:

119833554

CCRC:

123691618

HAW:

110374414

HZE:

124632280

TNL:

113508553

SLIU:

111358342

OFU:

114362489

PXY:

105386278

CFEL:

113385639 113385641

API:

100168657

DNX:	107161557 107170661

AGS:	114130228 114130233 114130327

RMD:	113548991 113554697

BTAB:

109038559

DCI:

108253431

CLEC:

106668903

HHAL:

106685842

NLU:

111047323

PHU:	Phum_PHUM123970

FOC:

113202302

TPAL:

117646756

ZNE:

110834248

CSEC:

111865742

SGRE:

126281939

FCD:

110860039

DPX:	DAPPUDRAFT_260253 DAPPUDRAFT_306906

DMK:

116922104

DPZ:

124338628

PVM:

113817360

PJA:

122246114

PCHN:

125033379

PMOO:

119577977

HAME:

121869349

PCLA:

123761319

PTRU:

123499404

HAZT:

108668231

EAF:

111703032

LSM:

121123680

PPOI:

119108336 119108503

ISC:	IscW_ISCW015479

DSV:

119453055

RSAN:

119400129

RMP:

119179775

VDE:

111254125

VJA:

111264301

TUT:

107370080

DPTE:

113793367 113799067

DFR:

124491997

CSCU:

111621256

PTEP:

107447699

SDM:

118204310

CEL:	CELE_C14B1.10(alkb-8)

CBR:	CBG_25960(Cbr-alkb-8)

BMY:	BM_BM2193(Bma-alkb-8)

LOA:	LOAG_09472

NAI:	NECAME_03859

TSP:	Tsp_12125 Tsp_13498a Tsp_15782 Tsp_16107

HRO:	HELRODRAFT_69129

LGI:	LOTGIDRAFT_143038

PCAN:

112560879

BGT:

106051347

GAE:

121376359

HRF:

124132652

HRJ:

124274595

CRG:

105318500

MYI:

110445761

PMAX:

117329000

MCAF:

127714236

MMER:

123557506

DPOL:

127876081

OBI:

106878852

OSN:

115218397

LAK:	106180537 112041439

SMM:	Smp_124160.1

OVI:	T265_05412

EGL:

EGR_05611

NVE:

5504540

EPA:

110252534

ATEN:

116300287

ADF:

107351190

AMIL:

114976071

PDAM:

113686830

SPIS:

111334431

DGT:

114524827

XEN:

124445621

HMG:

100207968

TAD:	TRIADDRAFT_26003

AQU:

100635888

ATH:	AT1G31600(TRM9) AT1G36310

ALY:	9327278 9329901

CRB:	17897569 17899581

CSAT:

104741763 104742087 104757812 104777194 104777497 104787286

EUS:	EUTSA_v10004311mg

BRP:	103833805 103848760 103867438

BNA:	106399512 106411637 106411643 106411644 106412207 106418960 106447489 111205055

BOE:	106307572 106308184 106342941

RSZ:	108813771 108819092

THJ:	104798532 104813129

CPAP:

110812544 110818506

CIT:	102616373 102625137

CIC:	CICLE_v10001407mg

PVY:	116131581 116143241

MINC:

123195808 123228866

TCC:	18592225 18606930

GRA:	105764921 105773784

GHI:	107918198 107946842 107946865

GAB:	108479336 108486729

DZI:	111275453 111295045 111312355

EGR:	104444193 104456636

GMX:	100777529 100784028 100807751

GSJ:	114409321 114415355 114424972

PVU:	PHAVU_002G123600g PHAVU_009G027100g

VRA:	106759935 106777615

VAR:	108329993 108335758

VUN:	114164818 114173430

CCAJ:

109796724 109815811

APRC:

113852660 113868611

MTR:	11416556 25488378

CAM:	101494433 101511642

PSAT:

127084163 127119896

LJA:	Lj0g3v0046209.1(Lj0g3v0046209.1) Lj0g3v0064359.1(Lj0g3v0064359.1) Lj2g3v1573010.1(Lj2g3v1573010.1) Lj2g3v1573010.2(Lj2g3v1573010.2)

ADU:	107460794 107487073

AIP:	107606112 107642443

AHF:	112706137 112747573 112767321 112800179

LANG:

109348998 109357026

FVE:	101301875 101305382

RCN:	112175228 112180448

PPER:

18776672 18788824

PMUM:

103332964 103336690

PAVI:

110753860 110755353

PDUL:

117615331 117628175

MDM:	103416044 103441609

PXB:

103955543

ZJU:	107422678 107430520

MNT:	21385544 21404370 21406663

CSV:	101210859 101216715

CMO:	103485433 103487636

BHJ:	120076615 120085248

MCHA:

111008031 111020230

CMAX:

111477075 111487507 111489322

CMOS:

111443258 111445406 111464581

CPEP:

111781823 111797701 111808235

RCU:	8263009 8280124

JCU:	105638853 105643385

HBR:	110640684 110644165 110667825

MESC:

110604451 110610008

POP:	18109215 7495129

PEU:	105127887 105128148

PALZ:

118028648 118041715

JRE:	109012454 109019322 109021366

CILL:

122282026 122313590

QSU:	112010177 112023712 112039268

QLO:	115969772 115972518

TWL:	120000712 120009105 120016236

VVI:	100252728 100262638

VRI:	117906577 117910167 117928117

SLY:	101260324 101263510

SPEN:

107005551 107015589

SOT:	102587122 102591578

SSTN:

125854891 125863178

CANN:

107850720 107867583

NTA:	107777356 107778504 107782177 107784057 107799087 107802481

NSY:	104228789 104231727 104246141

NTO:	104088120 104097471 104104403

NAU:	109212711 109213036 109240633

INI:	109170202 109170629

ITR:	115999840 116030543

SIND:

105159340 105164991

OEU:	111377742 111378936 111383327 111404274

EGT:	105957908 105959580

SSPL:

121753244 121755947 121759299 121783205

APAN:

127253844 127265525

HAN:	110868608 110918392

ECAD:

122584729 122607435

LSV:	111883014 111909289

CCAV:

112511520 112520698

DCR:	108194488 108212681

CSIN:

114316395 114318303

BVG:	104892444 104905687

SOE:	110774879 110797769

CQI:	110682734 110694955 110696487 110713354 110719361

NNU:	104600059 104610319

MING:

122073935 122080298 122081925

TSS:	122645111 122646875 122668072

PSOM:

113281896 113286943 113297538 113332003

OSA:

4330741

DOSA:

Os02t0750500-01(Os02g0750500) Os04t0602700-00(Os04g0602700)

OBR:

102703096

OGL:	127762408 127769470

BDI:	100827681 100835069

ATS:	109741229 109760172

TDC:	119317833 119324975 119356307

TAES:

123054398 123128353 123138210 123145461

TUA:

125514584

LPER:

127306152 127336329

SBI:

8066423

ZMA:	100282025 103627749

SITA:

101775180 101777379

SVS:	117838326 117862976

PVIR:

120641675 120641935 120657264 120688079

PHAI:

112883639 112900949

PDA:	103713010 103715224

EGU:	105033011 105053522

MUS:	103990395 103996326

ZOF:	122012432 122016345 122018778 122022443

DCT:	110097186 110106918

PEQ:	110017816 110036569

AOF:

109832664

NCOL:

116263365 116266349

ATR:	18422136 18422692

SMO:	SELMODRAFT_112271 SELMODRAFT_112315 SELMODRAFT_78643 SELMODRAFT_78730

PPP:

112285437

VCN:	VOLCADRAFT_108374

MNG:

MNEG_3576

APRO:

F751_1394

OLU:	OSTLU_88555

OTA:	OT_ostta11g00670 OT_ostta13g02300

BPG:	Bathy04g02310 Bathy13g02890

MIS:	MICPUN_60739 MICPUN_86885

MPP:	MICPUCDRAFT_17097 MICPUCDRAFT_41620

CME:	CYME_CMC092C

GSL:	Gasu_35150

CCP:	CHC_T00002663001

SCE:	YML014W(TRM9)

SEUB:

DI49_4075

SPAO:

SPAR_M01130

AGO:	AGOS_ADR181W

KLA:	KLLA0_B01023g

KMX:	KLMA_40600(TRM9)

LTH:	KLTH0G04158g

VPO:	Kpol_1023p89

ZRO:	ZYRO0D12936g

CGR:	CAGL0H04807g

NCS:	NCAS_0H02650(NCAS0H02650)

NDI:	NDAI_0C00970(NDAI0C00970)

TPF:	TPHA_0K00450(TPHA0K00450)

TBL:	TBLA_0A06960(TBLA0A06960)

TGB:	HG536_0A05620

TDL:	TDEL_0A04070(TDEL0A04070)

KAF:	KAFR_0C05480(KAFR0C05480)

KNG:	KNAG_0B03590(KNAG0B03590)

ZMK:	HG535_0D05100

PPA:	PAS_chr2-1_0406

DHA:	DEHA2E06116g

PIC:	PICST_53251(TRM9)

PGU:	PGUG_05578

SPAA:

SPAPADRAFT_59316

LEL:	LELG_03081

CAL:	CAALFM_CR08180CA(TRM9)

CTP:	CTRG_03035 CTRG_03049

COT:	CORT_0G02400

CDU:	CD36_33810

CTEN:

CANTEDRAFT_119620

YLI:	YALI0D12837g

CLU:	CLUG_02894

CLUS:

A9F13_18g00121

CAUR:

CJI97_003917

PKZ:	C5L36_0B05370

BNN:	FOA43_003977

BBRX:

BRETT_000702

OPA:	HPODL_04856

SLUD:

SCDLUD_003322

NCR:	NCU01705 NCU09959

NTE:	NEUTE1DRAFT74900(NEUTE1DRAFT_74900) NEUTE1DRAFT83783(NEUTE1DRAFT_83783)

SMP:	SMAC_02412 SMAC_09505

PAN:	PODANSg267 PODANSg6505

TTT:	THITE_2109182 THITE_2124421

MTM:	MYCTH_2302938 MYCTH_2312616

CTHR:

CTHT_0008400 CTHT_0064220

MGR:

MGG_14001

PPEI:

PpBr36_10819

TMN:	UCRPA7_4460

SSCK:

SPSK_09477

FGR:	FGSG_00319

FPU:	FPSE_07691

FVR:	FVEG_00768

FOX:	FOXG_00748

NHE:	NECHADRAFT_98875

TRE:	TRIREDRAFT_102855

TRR:	M419DRAFT_67572

MAW:

MAC_06558

MAJ:

MAA_07627

CMT:

CCM_04762

PLJ:	VFPFJ_04819 VFPFJ_07021

VAL:	VDBG_07133

VDA:	VDAG_06775

CFJ:	CFIO01_13405

CLUP:

CLUP02_00806

CHIG:

CH63R_12743

ELA:	UCREL1_550

PFY:	PFICI_15018

SSL:	SS1G_01858 SS1G_03786

BFU:	BCIN_02g02290(Bctrm9) BCIN_04g03650

MBE:

MBM_02302

PSCO:

LY89DRAFT_658762

GLZ:	GLAREA_12235

ANI:

AN5119.2

AFM:	AFUA_1G07570

ACT:	ACLA_027030

NFI:	NFIA_017170

AOR:	AO090012001009

ANG:	ANI_1_1304064(An07g10200)

AFV:	AFLA_002733

ALUC:

AKAW2_11274S(TRM9)

ACHE:

ACHE_11257S(TRM9)

APUU:

APUU_41214A(TRM9)

PCS:	Pc12g05260

PDP:	PDIP_34580

TMF:	PMAA_096130

TRG:	TRUGW13939_11498

CIM:	CIMG_02532

CPW:	CPC735_037900

URE:	UREG_03197

PBL:	PAAG_08025

PBN:	PADG_08090

ABE:

ARB_04238

TVE:

TRV_05273

AJE:	HCAG_02062

BGH:	BDBG_06041

PNO:	SNOG_01346

PTE:

PTT_18672

BZE:	COCCADRAFT_94651

BSC:	COCSADRAFT_257765

BOR:	COCMIDRAFT_102480

AALT:

CC77DRAFT_991231

ZTR:	MYCGRDRAFT_36443

PFJ:	MYCFIDRAFT_29298

FFU:	CLAFUR5_02880

NPA:	UCRNP2_1011

TML:	GSTUM_00009410001

SPO:	SPAC13D6.03c(trm9)

CNE:

CNG00280

CNB:

CNBG4490

CNG:	CNAG_07748

CGI:	CGB_G6420C

TMS:	TREMEDRAFT_36141

TASA:

A1Q1_01231

TVS:	TRAVEDRAFT_175821

DSQ:	DICSQDRAFT_49632

SHS:	STEHIDRAFT_153743

HIR:	HETIRDRAFT_14892

PSQ:	PUNSTDRAFT_114868

FME:	FOMMEDRAFT_79111

GTR:	GLOTRDRAFT_126680

LBC:	LACBIDRAFT_316000

CCI:	CC1G_03924

ABP:	AGABI1DRAFT97973(AGABI1DRAFT_97973)

ABV:	AGABI2DRAFT148979(AGABI2DRAFT_148979)

MRR:	Moror_6463

E1B28_008731

SCM:	SCHCO_02606184(SCHCODRAFT_02606184)

CPUT:

CONPUDRAFT_87550

SLA:	SERLADRAFT_363113

WSE:	WALSEDRAFT_60459

WIC:	J056_002916

UMA:	UMAG_10709

MRT:

MRET_3516

MSYM:

MSY001_0392

PGR:	PGTG_04654 PGTG_20366

MLR:	MELLADRAFT_76777

ECU:	ECU09_1500

EIN:	Eint_091190

EHE:	EHEL_091160

ERO:	EROM_090900

NCE:	NCER_101265

MBR:	MONBRDRAFT_25170

SRE:	PTSG_04730

DDI:	DDB_G0292448

DPP:	DICPUDRAFT_58748

DFA:

DFA_09055

EDI:	EDI_187020

EIV:	EIN_344210

ACAN:

ACA1_266340

PYO:	PY17X_0513200

PCB:	PCHAS_0512200

PBE:	PBANKA_0512100

PKN:	PKNH_0612400

PVX:	PVX_111320

PCY:	PCYB_062210

TPV:

TP01_0568

TOT:	TOT_010000528

BEQ:	BEWA_001730

BBO:	BBOV_I002790

BMIC:

BMR1_01G00967

CPV:	cgd7_1000 cgd7_630

CHO:	Chro.70078 Chro.70124

TGO:	TGME49_248960

TET:	TTHERM_01143900

PTM:	GSPATT00006150001 GSPATT00014589001

SMIN:

v1.2.016030.t1(symbB.v1.2.016030.t1)

FCY:	FRACYDRAFT_161237 FRACYDRAFT_185395

NGD:	NGA_2105200

AAF:	AURANDRAFT_15079

PIF:	PITG_02033 PITG_03063

PSOJ:

PHYSODRAFT_471314 PHYSODRAFT_491312

SPAR:

SPRG_08500 SPRG_08773

EHX:	EMIHUDRAFT_240478

GTT:	GUITHDRAFT_115004 GUITHDRAFT_157249

LIF:	LINJ_36_2780

LDO:	LDBPK_362780

LMI:	LMXM_36_2650

LBZ:	LBRM_35_2860

LPAN:

LPMP_352710

NGR:	NAEGRDRAFT_58773 NAEGRDRAFT_958

TVA:	TVAG_2v0181540 TVAG_2v0919850

RDE:

RD1_4214

RLI:	RLO149_c037220

CFF:	CFF8240_1554

CFT:	CFF04554_1563

CFZ:

CSG_16900

EYY:	EGYY_11160

APV:

Apar_0905

ATB:	J4859_02955

CGO:	Corgl_0595

CSTC:

LK434_05380

DET:

DET0611

DEH:

cbdbA594

DEB:	DehaBAV1_0585

DEV:

DhcVS_550

DEG:	DehalGT_0547

DMC:

btf_572

DMD:

dcmb_618

DMG:

GY50_0538

DMX:	X792_02975

DMY:	X793_02720

DMZ:	X794_02460

DUC:	UCH007_05340

DLY:	Dehly_0734

DETH:

HX448_06355

ATM:

ANT_05350

ABAT:

CFX1CAM_1915

PSUB:

Pelsub_P0558

ABAO:

BEQ56_11730

CAP:	CLDAP_10540

PBF:	CFX0092_A0371

PMET:

G4Y79_07415

APRD:

HLG78_02375

SRG:	XF24_00863

TMG:	US01_C0001G0671

WWE:	P147_WWE3C01G0370

HAL:

VNG_0821C

HSL:

OE_2210R

HDL:	HALDL1_08540

HHB:

Hhub_1989

HAGS:

JT689_04645

HABO:

JRZ79_03150

HNO:	LT974_04865

HLU:	LT972_08155

HANR:

LJ422_03370

HJE:	HacjB3_11040

HALH:

HTSR_0801

HHSR:

HSR6_0828

HSU:	HLASF_1487

HSF:	HLASA_1474

SALR:

FQU85_10580

HALR:

EFA46_009620

HAAD:

MW046_09655

HALX:

M0R89_13595

HAXZ:

M0R88_13970

SALI:

L593_07745

SAIM:

K0C01_08385

HARA:

AArcS_1515

HMA:

rrnAC0542

HHI:

HAH_1099

HHN:	HISP_05640

HAB:	SG26_13300

HTA:	BVU17_05370

HALJ:

G9465_10120

HSIN:

KDQ40_07985

NPH:

NP_3110A

NMO:

Nmlp_1349

NHO:	HWV23_14975

NSAL:

HWV07_00210

HUT:

Huta_2530

HTI:

HTIA_2295

HALA:

Hrd1104_07230

HMU:

Hmuk_2566

HALZ:

E5139_00095

HALL:

LC1Hm_1905(trm9)

HAZP:

GBQ70_00095

HALI:

BV210_00725

HSN:	DV733_14080

HDS:	HSR122_0729

HRR:	HZS55_20015

HPEL:

HZS54_23515

HLT:	I7X12_17070

HARC:

HARCEL1_09675

HDO:	MUK72_12900

SSAI:

N0B31_08890

HWA:

HQ_1601A

HWC:

Hqrw_1711

HVO:

HVO_1032

HME:

HFX_1030

HGI:	ABY42_04995

HALE:

G3A49_08395

HLS:	KU306_09765

HBO:	Hbor_22130

HAQ:	DU484_11715

HAJ:	DU500_11990

HAER:

DU502_11250

HRA:	EI982_18070

HLM:	DV707_13250

HALM:

FCF25_12190

HLA:

Hlac_1030

HALP:

DOS48_05535

HALB:

EKH57_07020

HEZZ:

EO776_05410

HALQ:

Hrr1229_000875

HSS:	J7656_11300

HSAI:

HPS36_01575

HAZZ:

KI388_02875

SRUB:

C2R22_06565

HAE:	halTADL_0018

HALN:

B4589_002080

HALG:

HUG10_02520

HALU:

HUG12_14500

HMP:	K6T50_01005

HRE:	K6T36_00780

HRM:	K6T25_00440

HACB:

Hbl1158_07990

HDF:	AArcSl_1021

HAH:	Halar_1393

HTU:

Htur_1066

HDA:	BB347_03155

HSAL:

JMJ58_03425

HLO:	J0X27_04380

HAKZ:

J0X25_13190

NMG:

Nmag_3224

HXA:	Halxa_3715

NAT:

NJ7G_3238

NPE:	Natpe_2803

NVR:	FEJ81_13875

NPL:	FGF80_13500

NAY:	HYG81_17020

HALY:

HYG82_20335

HJT:	DVR14_04025

NGE:	Natgr_0728

HRU:	Halru_0760

HALV:

NGM15_06580

NOU:	Natoc_1030

HLR:	HALLA_09920

HLC:	CHINAEXTREME19915

NAJ:	B1756_14920

NAG:	AArcMg_1730

NAN:	AArc1_1926

NBG:	DV706_01805 DV706_19455

NAS:	GCU68_11935

SAWL:

NGM29_15360

DKA:

DKAM_0609

DFD:	Desfe_0711

TAG:

Tagg_0551

IAG:

Igag_1818

STO:

STK_16210

SOH:	D1869_09125

SACN:

SacN8_08010

SACR:

SacRon12I_08020

SACS:

SUSAZ_07815

SID:

M164_1674

SIH:

SiH_1601

SIR:

SiRe_1522

SIC:

SiL_1514

SULE:

GFS03_09170

AHO:

Ahos_0077

ABRI:

DFR85_02015

ASUL:

DFR86_01950

AAMB:

D1866_07275

SAZO:

D1868_05650

PIS:

Pisl_1163

PCL:

Pcal_0086

PYR:

P186_2374

POG:

Pogu_2359

TNE:

Tneu_0119

CMA:

Cmaq_0994

VDI:

Vdis_0251

VMO:

VMUT_1382

THB:	N186_08395

KCR:

Kcr_0966

PSYT:

DSAG12_02304

» show all

Reference

1 [PMID:20308323]

Authors

Fu D, Brophy JA, Chan CT, Atmore KA, Begley U, Paules RS, Dedon PC, Begley TJ, Samson LD

Title

Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival.

Journal

Mol Cell Biol 30:2449-59 (2010)
DOI:10.1128/MCB.01604-09

Sequence

[hsa:91801]

Reference

2 [PMID:20123966]

Authors

Songe-Moller L, van den Born E, Leihne V, Vagbo CB, Kristoffersen T, Krokan HE, Kirpekar F, Falnes PO, Klungland A

Title

Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding.

Journal

Mol Cell Biol 30:1814-27 (2010)
DOI:10.1128/MCB.01602-09

Sequence

[hsa:91801] [mmu:67667]

Reference

3 [PMID:14645538]

Authors

Kalhor HR, Clarke S

Title

Novel methyltransferase for modified uridine residues at the wobble position of tRNA.

Journal

Mol Cell Biol 23:9283-92 (2003)
DOI:10.1128/MCB.23.24.9283-9292.2003

Sequence

[sce:YML014W]

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.229

IUBMB Enzyme Nomenclature:

2.1.1.229

ExPASy - ENZYME nomenclature database:

2.1.1.229

BRENDA, the Enzyme Database:

2.1.1.229

All links

Gene (4871)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (1225)   
   KEGG MGENES (1282)   
   RefGene (2362)   
Protein sequence (966)   
   UniProt (938)   
   SWISS-PROT (8)   
   RefSeq(pep) (20)   
DNA sequence (73)   
   RefSeq(nuc) (29)   
   GenBank (24)   
   EMBL (20)   
Protein domain (10)   
   InterPro (10)   
All databases (5920)   

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