KEGG   ENZYME: 2.1.1.273
Entry
EC 2.1.1.273                Enzyme                                 
Name
benzoate O-methyltransferase;
BAMT;
S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:benzoate O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + benzoate = S-adenosyl-L-homocysteine + methyl benzoate [RN:R10447]
Reaction(KEGG)
R10447
Substrate
S-adenosyl-L-methionine [CPD:C00019];
benzoate [CPD:C00180]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
methyl benzoate [CPD:C20645]
Comment
While the enzyme from the plant Zea mays is specific for benzoate [6], the enzymes from Arabidopsis species and Clarkia breweri also catalyse the reaction of EC 2.1.1.274, salicylate 1-O-methyltransferase [1,5]. In snapdragon (Antirrhinum majus) two isoforms are found, one specific for benzoate [2,3] and one that is also active towards salicylate [4]. The volatile product is an important scent compound in some flowering species [2].
History
EC 2.1.1.273 created 2013
Orthology
K21482  benzoate O-methyltransferase
K21484  benzoate/salicylate 1-O-methyltransferase
Genes
ATHAT3G11480(BSMT1) AT5G04370(NAMT1) AT5G04380 AT5G66430
ALY9320913
CRB17893670
CSAT104708682 104727399 104734448 104745350 104745353 104745842 104746543 104762932 104764901 104766009 104768626 104773442 109130817
EUSEUTSA_v10013754mg EUTSA_v10022292mg
BRP103837152 103847295 103847297 103847298 103847299 103855566 103859391 103870342 103870344
BNA106345178 106345495 106346584 106353051 106362614 106364005 106366900 106370700 106372697 106372698 106383478 106416291 106416341 106423490 106436478 106436480 106436482 106440340 106442990 111215743 111215744
BOE106302931 106313641 106316499 106318326 106318327 106329214 106332554
RSZ108814453 108816075 108818257 108846057 108857765 108859694 108860654 108861249
THJ104819197 104819198 104820147
CPAP110822348 110822461 110826209
CIT102624846 102625129 102625698
TCC18589945
GRA105775995
GHI107915639 107953092
DZI111309877
POP7487202
PALZ118056955
JRE108983849
VVI100249594 100266757
VRI117912404 117913130 117913186
SLY101254028 101254332
SPEN107001190 107015380 107015389
SOT102597978 102598302 102598971 102599293
CANN107857182
NTA107766085 107799152
NSY104246528
NTO104120721
SIND105173412 105173413 105173418 105173794
EGT105952352 105954778 105954779 105966293
HAN110889844 110889847 110923123
ECAD122592138 122592141 122592173 122608325 122608527
LSV111906000 111906002 111906004 111906005 111908135 111913950
CCAV112504667
DCR108203055
CSIN114306756 114321136
NNU104595931
OSA9267163 9272356
OBR102706569
TAES123157742 123169982
SBI110434364
ZMA100282829 103628300
SITA101766563
SVS117845571
PHAI112882088
 » show all
Reference
1  [PMID:10375393]
  Authors
Ross JR, Nam KH, D'Auria JC, Pichersky E
  Title
S-Adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme involved in floral scent production and plant defense, represents a new class of plant methyltransferases.
  Journal
Arch Biochem Biophys 367:9-16 (1999)
DOI:10.1006/abbi.1999.1255
Reference
2  [PMID:10852939]
  Authors
Dudareva N, Murfitt LM, Mann CJ, Gorenstein N, Kolosova N, Kish CM, Bonham C, Wood K
  Title
Developmental regulation of methyl benzoate biosynthesis and emission in snapdragon flowers.
  Journal
Plant Cell 12:949-61 (2000)
DOI:10.1105/tpc.12.6.949
  Sequence
Reference
3  [PMID:11051108]
  Authors
Murfitt LM, Kolosova N, Mann CJ, Dudareva N
  Title
Purification and characterization of S-adenosyl-L-methionine:benzoic acid carboxyl methyltransferase, the enzyme responsible for biosynthesis of the volatile ester methyl benzoate in flowers of Antirrhinum majus.
  Journal
Arch Biochem Biophys 382:145-51 (2000)
DOI:10.1006/abbi.2000.2008
Reference
4  [PMID:12361714]
  Authors
Negre F, Kolosova N, Knoll J, Kish CM, Dudareva N
  Title
Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is  not involved in floral scent production in snapdragon flowers.
  Journal
Arch Biochem Biophys 406:261-70 (2002)
DOI:10.1016/S0003-9861(02)00458-7
Reference
5  [PMID:14617060]
  Authors
Chen F, D'Auria JC, Tholl D, Ross JR, Gershenzon J, Noel JP, Pichersky E
  Title
An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense.
  Journal
Plant J 36:577-88 (2003)
DOI:10.1046/j.1365-313X.2003.01902.x
  Sequence
[ath:AT3G11480]
Reference
6  [PMID:20519632]
  Authors
Kollner TG, Lenk C, Zhao N, Seidl-Adams I, Gershenzon J, Chen F, Degenhardt J
  Title
Herbivore-induced SABATH methyltransferases of maize that methylate anthranilic acid using s-adenosyl-L-methionine.
  Journal
Plant Physiol 153:1795-807 (2010)
DOI:10.1104/pp.110.158360
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.273
IUBMB Enzyme Nomenclature: 2.1.1.273
ExPASy - ENZYME nomenclature database: 2.1.1.273
BRENDA, the Enzyme Database: 2.1.1.273

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