KEGG   ENZYME: 2.1.1.278Help
Entry
EC 2.1.1.278                Enzyme                                 

Name
indole-3-acetate O-methyltransferase;
IAA carboxylmethyltransferase;
IAMT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + (indol-3-yl)acetate = S-adenosyl-L-homocysteine + methyl (indol-3-yl)acetate [RN:R10452]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
(indol-3-yl)acetate [CPD:C00954]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
methyl (indol-3-yl)acetate [CPD:C20635]
Comment
Binds Mg2+. The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. The product, methyl (indol-3-yl)acetate is inactive as hormone [2].
History
EC 2.1.1.278 created 2013
Orthology
K18848  indole-3-acetate O-methyltransferase
Genes
ATH: AT5G55250(IAMT1)
ALY: ARALYDRAFT_495611
CRB: 17876787
CSAT: 104726072 104731592 104761558 109127202
EUS: EUTSA_v10015669mg
BRP: 103844968
BNA: 106429974
BOE: 106314016
THJ: 104811634 104817688
CPAP: 110820813
CIT: 102609472
TCC: 18593419
GRA: 105781276
CAM: 101501068
LJA: Lj2g3v3222870.1(Lj2g3v3222870.1) Lj6g3v0819010.1(Lj6g3v0819010.1)
FVE: 101295605
CSV: 101213472
CMO: 103490122
RCU: 8268129
JCU: 105633024
VVI: 100258858
CANN: 107877415
SIND: 105174912
HAN: 110890061
LSV: 111898207
DCR: 108216756
SOE: 110777861
DOSA: Os04t0665200-01(Os04g0665200) Os06t0322400-00(Os06g0322400) Os06t0323100-01(Os06g0323100)
PDA: 103702327
EGU: 105050524
ATR: 18429711
 » show all
Taxonomy
Reference
1  [PMID:12897246]
  Authors
Zubieta C, Ross JR, Koscheski P, Yang Y, Pichersky E, Noel JP
  Title
Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family.
  Journal
Plant Cell 15:1704-16 (2003)
DOI:10.1105/tpc.014548
  Sequence
[ath:AT5G55250]
Reference
2  [PMID:17926040]
  Authors
Li L, Hou X, Tsuge T, Ding M, Aoyama T, Oka A, Gu H, Zhao Y, Qu LJ
  Title
The possible action mechanisms of indole-3-acetic acid methyl ester in Arabidopsis.
  Journal
Plant Cell Rep 27:575-84 (2008)
DOI:10.1007/s00299-007-0458-9
  Sequence
[ath:AT5G55250]
Reference
3  [PMID:18162595]
  Authors
Zhao N, Ferrer JL, Ross J, Guan J, Yang Y, Pichersky E, Noel JP, Chen F
  Title
Structural, biochemical, and phylogenetic analyses suggest that indole-3-acetic acid methyltransferase is an evolutionarily ancient member of the SABATH family.
  Journal
Plant Physiol 146:455-67 (2008)
DOI:10.1104/pp.107.110049
  Sequence
[osa:4337315]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.278
IUBMB Enzyme Nomenclature: 2.1.1.278
ExPASy - ENZYME nomenclature database: 2.1.1.278
BRENDA, the Enzyme Database: 2.1.1.278

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