KEGG   ENZYME: 2.1.1.295Help
Entry
EC 2.1.1.295                Enzyme                                 

Name
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase;
VTE3 (gene name);
2-methyl-6-solanyl-1,4-hydroquinone methyltransferase;
MPBQ/MSBQ methyltransferase;
MPBQ/MSBQ MT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:2-methyl-6-phytyl-1,4-benzoquinol C-3-methyltransferase
Reaction(IUBMB)
(1) S-adenosyl-L-methionine + 2-methyl-6-phytylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytylbenzene-1,4-diol [RN:R07501];
(2) S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol = S-adenosyl-L-homocysteine + plastoquinol [RN:R10709];
(3) S-adenosyl-L-methionine + 6-geranylgeranyl-2-methylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol [RN:R10710]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
2-methyl-6-phytylbenzene-1,4-diol [CPD:C15882];
2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol [CPD:C17570];
6-geranylgeranyl-2-methylbenzene-1,4-diol [CPD:C20737]
Product
plastoquinol [CPD:C16695]
Comment
Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols).
History
EC 2.1.1.295 created 2014
Pathway
ec00130  Ubiquinone and other terpenoid-quinone biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K12502  MPBQ/MSBQ methyltransferase
K18534  MPBQ/MSBQ methyltransferase
Genes
ATH: AT3G63410(APG1)
ALY: ARALYDRAFT_907927
CRB: 17887229
CSAT: 104699535 104699536 104748980 104788679 104788680
EUS: EUTSA_v10006087mg
BRP: 103830388
BNA: 106353332 106410579
BOE: 106300824
RSZ: 108818362
THJ: 104801966 104804929 104823034
CPAP: 110823242
EGR: 104427271
MTR: 11429739
LJA: Lj5g3v1014830.1(Lj5g3v1014830.1) Lj5g3v1208090.1(Lj5g3v1208090.1)
CSV: 101218864
CMO: 103491265
MCHA: 111015269
SIND: 105163320
OEU: 111375743
BVG: 104894575
DOSA: Os07t0179300-00(Os07g0179300) Os12t0615400-01(Os12g0615400)
OBR: 102717119
ATS: 109753840(LOC109753840) 109759333(LOC109759333) 109759692(LOC109759692)
ZMA: 100284931
SITA: 101777009
PDA: 103716169
EGU: 105055609
MUS: 103975699
DCT: 110110033
AOF: 109833025
ATR: 18429566
MNG: MNEG_2018
APRO: F751_0698
FCY: FRACYDRAFT_277748(VTE3)
SYN: sll0418
SYY: SYNGTS_1914(sll0418)
SYT: SYNGTI_1913(sll0418)
SYS: SYNPCCN_1912(sll0418)
SYQ: SYNPCCP_1912(sll0418)
SYJ: D082_05990(erg6)
SYW: SYNW2141
SYC: syc0927_c
SYG: sync_0378
CYA: CYA_0166
CYB: CYB_0976
SYNR: KR49_10590
SYND: KR52_00850
TEL: tll1726
THN: NK55_05270(vte3)
LET: O77CONTIG1_03739(rebM_3)
PMA: Pro_1661
PMM: PMM1505
PMT: PMT_1785
PRC: EW14_1844
PRM: EW15_2010
AMR: AM1_4828
MAR: MAE_31670
MPK: VL20_1779
CYT: cce_2731
TER: Tery_2173
ANA: all2121
AVA: Ava_1078
CALH: IJ00_04090
CEO: ETSB_0305
NJA: NSJP_3545
 » show all
Taxonomy
Reference
1  [PMID:11821038]
  Authors
Shintani DK, Cheng Z, DellaPenna D
  Title
The role of 2-methyl-6-phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803.
  Journal
FEBS Lett 511:1-5 (2002)
DOI:10.1016/S0014-5793(01)03223-9
  Sequence
[syn:sll0418]
Reference
2  [PMID:14508009]
  Authors
Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D.
  Title
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.
  Journal
Plant Cell 15:2343-56 (2003)
DOI:10.1105/tpc.013656
  Sequence
Reference
3  [PMID:14630966]
  Authors
Van Eenennaam AL, Lincoln K, Durrett TP, Valentin HE, Shewmaker CK, Thorne GM, Jiang J, Baszis SR, Levering CK, Aasen ED, Hao M, Stein JC, Norris SR, Last RL
  Title
Engineering vitamin E content: from Arabidopsis mutant to soy oil.
  Journal
Plant Cell 15:3007-19 (2003)
DOI:10.1105/tpc.015875
  Sequence
[ath:AT3G63410] [ana:all2121]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.295
IUBMB Enzyme Nomenclature: 2.1.1.295
ExPASy - ENZYME nomenclature database: 2.1.1.295
BRENDA, the Enzyme Database: 2.1.1.295

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