KEGG   ENZYME: 2.1.1.312Help
Entry
EC 2.1.1.312                Enzyme                                 

Name
25S rRNA (uracil2843-N3)-methyltransferase;
BMT6
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:tRNA (uracil2843-N3)-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + uracil2843 in 25S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil2843 in 25S rRNA
Substrate
S-adenosyl-L-methionine [CPD:C00019];
uracil2843 in 25S rRNA
Product
S-adenosyl-L-homocysteine [CPD:C00021];
N3-methyluracil2843 in 25S rRNA
Comment
The enzyme, described from the yeast Saccharomyces cerevisiae, is involved in ribosome biogenesis.
History
EC 2.1.1.312 created 2014
Orthology
K19308  25S rRNA (uracil2843-N3)-methyltransferase
Genes
QSU: 111992908 112016728
SCE: YLR063W(BMT6)
AGO: AGOS_ACR222W
ERC: Ecym_1512
KLA: KLLA0_D05203g
KMX: KLMA_70060
LTH: KLTH0G18700g
VPO: Kpol_1058p17
ZRO: ZYRO0F02926g
CGR: CAGL0F01661g
NCS: NCAS_0J00400(NCAS0J00400)
NDI: NDAI_0C06480(NDAI0C06480)
TPF: TPHA_0P00220(TPHA0P00220)
TBL: TBLA_0D02430(TBLA0D02430)
TDL: TDEL_0C00550(TDEL0C00550)
KAF: KAFR_0D00970(KAFR0D00970)
CAL: CAALFM_CR01780WA(CaO19.2575)
SLB: AWJ20_5181(BMT6)
NCR: NCU01329
NTE: NEUTE1DRAFT34580(NEUTE1DRAFT_34580)
MGR: MGG_02469
SSCK: SPSK_05334
MAW: MAC_01146
MAJ: MAA_05588
CMT: CCM_03476
BFU: BCIN_14g01890(Bcbmt6)
ANI: AN0685.2
ANG: ANI_1_2058074(An08g06530)
ABE: ARB_01752
TVE: TRV_01322
PTE: PTT_15390
CNE: CNE00650
CNB: CNBE0590
 » show all
Taxonomy
Reference
1  [PMID:24335083]
  Authors
Sharma S, Yang J, Duttmann S, Watzinger P, Kotter P, Entian KD
  Title
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae.
  Journal
Nucleic Acids Res 42:3246-60 (2014)
DOI:10.1093/nar/gkt1281
  Sequence
[sce:YLR063W]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.312
IUBMB Enzyme Nomenclature: 2.1.1.312
ExPASy - ENZYME nomenclature database: 2.1.1.312
BRENDA, the Enzyme Database: 2.1.1.312

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