KEGG   ENZYME: 2.1.1.334
Entry
EC 2.1.1.334                Enzyme                                 
Name
methanethiol S-methyltransferase;
mddA (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:methanethiol S-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + methanethiol = S-adenosyl-L-homocysteine + dimethyl sulfide [RN:R11546]
Reaction(KEGG)
R11546
Substrate
S-adenosyl-L-methionine [CPD:C00019];
methanethiol [CPD:C00409]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
dimethyl sulfide [CPD:C00580]
Comment
The enzyme, found in many bacterial taxa, is involved in a pathway that converts L-methionine to dimethyl sulfide.
History
EC 2.1.1.334 created 2016
Pathway
ec00920  Sulfur metabolism
ec01100  Metabolic pathways
Orthology
K21310  methanethiol S-methyltransferase
Genes
YELLC20_02693
YHID5F51_08825
SLQM495_04985
PVCG3341_08015
PSUWWQ53_09920
LYJFKV23_01610
LSOLGOY17_10880
LSXH8B22_04980
XBCELE36_12935
FSGLQ771_13285
FEDLQ772_14875
DJAHY57_09935
VKABTD91_20750
PREPCA10_21890
PFUWKF707C_33770
PFNHZ99_00795
PFBVO64_5660
PAZOAYR47_25005
PRXHRH33_16290
PFWPF1751_v1c30210
PFFPFLUOLIPICF721090
PSKU771_19100
PFZAV641_17325
PLQAA042_16410
PPSYAOC04_14575
PSETTHL1_2198
POJPtoMrB4_21910
PLALFXN65_10180
PSAMHU731_003585
PTZHU718_017395
PTKEXN22_15340
PTWTUM18999_22770
PCAVD3880_13910
PNBNK667_06095
PSOAPSm6_60160
MSQBKP64_15570
MARAD0851_18950
KAKKalk_00940 Kalk_16030
GPSC427_2071
LALAT746_03355
SALHHMF8227_02551
OSGBST96_11275
MBRGPVT68_13945
CYQQ91_2161
CZACYCME_0261
CYYCPC19_02000
TIGTHII_1134
TEETel_03540 Tel_07835 Tel_15790
SROSBBH56_02705
SPIZGJ672_06210
NAXHC341_06185
GAIIMCC3135_20625
TBNTBH_C2756
EPSL0Y14_15645
TTCFOKN1_0851 FOKN1_1887
THICTspCOW1_07630 TspCOW1_18210
HCHHCH_07018
HAHEENC22_30485
HAHHO5O45_25535
HAKKO116_P100020
HTXEKK97_04295
KKOKkor_2188
SLIMSCL_1908
SVASVA_3646
SEDSAAY24_13775
GKNPVT67_17905
ENMEBS_0312
CTIpRALTA_0314
CCUPBKK81_28105
CUPBKK80_22065
BGLbglu_3p1140
RFRRfer_0359
HPSEHPF_12860
CBABSMCB_1610
RGUA4W93_17455
MENYLSQ66_15985
SLTSlit_1216
SEMEMIZ01_1753
SDRSCD_n01169
SLACSKTS_04810
URUDSM104443_01185(mddA2)
OTROTERR_17240
APETToN1_34940
AZAAZKH_0967
AZIAzCIB_0841
AZDCDA09_05120
TMZTmz1t_3864
THUAC731_013495
THAUC4PIVTH_1540
ACOMCEW83_03375
BEBABWI17_20985
BJAblr1218(blr1218) blr5741(blr5741)
BJUBJ6T_39950 BJ6T_86370
BJPRN69_19390 RN69_41710
BRABRADO0716 BRADO6625
BBTBBta_0910 BBta_7385
BRSS23_08390 S23_25090
AOLS58_69050
BRCBCCGELA001_33550
BRADBF49_4049 BF49_5906
BICLMTR13_12915
BROBRAD285_0211
BRKCWS35_33705
BOTCIT37_16210 CIT37_25595 CIT37_39470
BRQCIT40_02495 CIT40_20695
BGQX265_14955 X265_33805
BSYMCIT39_00950 CIT39_07755 CIT39_20025
BBETF8237_17865 F8237_19115 F8237_27600
BARHWN72_32005 WN72_45170
BVZBRAD3257_0832
BDGLPJ38_01135
BSEPHAP48_0048180
BBANJ4G43_033245 J4G43_034335 J4G43_048295
BCANBcanWSM471_05235 BcanWSM471_25480
BCOUIC761_04600 IC761_33850
BXNI3J27_03965 I3J27_24750
BROSQUH67_11270 QUH67_12530 QUH67_23685
BRAZLRP30_07715 LRP30_39970
RPATX73_014680
RPTRpal_3176
NHANham_4413
TRBHB776_10490
BOPAXW83_20085
BVVBHK69_12935
METM446_6423
MNOMnod_5015
MMESMMSR116_02335
HDTHYPDE_23693
RHZRHPLAN_57630
MCGGL4_1232 GL4_3051
MMEDMame_05043
BRND1F64_03695
NOHG5V57_24760
LIZLGH83_18265
CAUFCSW63_01220
CAULKCG34_10030
RDERD1_0738
DSHDshi_3401
OATOAN307_c35280 OAN307_c44610 OAN307_c45110
OAROA238_c17280
LEJETW24_02955
REDroselon_03608
SULZC1J03_01110
SMEDJNX03_02535 JNX03_19835
SUALKDD17_10225
ROTFIV09_05270
TGLHFZ77_01640
LSALKBK07_07160
LALGLentiSH36_00721
LVSLOKVESSMR4R_02996
RBGBG454_15320
POZI0K15_16380
MMRMmar10_2587
HBAHbal_1129
NPPPP1Y_AT23345
NPNJI59_04765
NREBES08_30055
NOVTQ38_006235
NGFFRF71_00710
SPHKSKP52_05030
SPHXE5675_13960
SPHDHY78_28265
RDICMV14_24260 CMV14_25270
SSANNX02_p1080
SRHIH9L12_11025
SPAIFPZ24_04525
SSAUH8M03_06770
SGLCM1K48_10585
SNOSK8P63_00220
SDONM9980_12605
SJPSJA_C1-04750
SINBSIDU_12140
SCHSphch_4171
SSYSLG_p_00950
SYBTZ53_22565
SBDATN00_20835
SPHTK426_27180
SCLOSCLO_2001410
SUFLFIL70_24600
SBARH5V43_23035
SAMISAMIE_3000890
SPPHKFK14_17275
SPHJBSL82_06745 BSL82_19500
SPZRG5C33_17185
PALGHFP57_08745
AEPAMC99_00869
ALBAEB_P2660
ALHG6N82_13335
ARUEQQX03_04975
ADOA6F68_01773
CNAAB433_05635
CMANA9D14_19270
ERKCD351_04790
EMVHQR01_02510
PORLBG023_11651
ACRAcry_3040
AMVACMV_33840
MAGXXM1_0220
MAGNWV31_03515
FERFNB15_06080 FNB15_08750
MAGQMGMAQ_0034
NACINUH88_04040
MGMMmc1_3239
KOZKFF44_03850
TMKQGN29_09620
SBALHUE88_06550
SULRB649_04520
NSANitsa_1478
SUNSUN_0917
SLHYH65_06895
GSKKN400_1952
GMEGmet_1980
GAOA2G06_07225
GURGura_2810
GLOGlov_1324
PPDPpro_0660
DEUDBW_0197 DBW_0279
DVEDESUT3_18100
DFLDFE_1424
DBADbac_2950
DESUNLA06_14680
DPRDespr_2725
DOGHP555_05215
DBKDGMP_31450
DALDalk_2434
DOVDSCO28_56870
DWDDSCW_40390
DALKDSCA_45860
DLIdnl_44050
DTIDesti_4457
SURSTAUR_4994
AVMJQX13_36910
CFUSCYFUS_003384
SAMYDB32_000175
NANNO0S08_44095
DMTDESME_10330
DAEDtox_2171
CTHMCFE_1060
ABUTAmi103574_08025
CHYCHY_1640
MTURv3238c
MTVRVBD_3238c
MTCMT3335
MRAMRA_3279
MTFTBFG_13267
MTBTBMG_03286
MTKTBSG_03309
MTZTBXG_003266
MTGMRGA327_19930
MTIMRGA423_20295
MTECCDC5079_2988
MTURCFBS_3427
MTLCCDC5180_2950
MTOMTCTRI2_3305
MTDUDA_3238c
MTNERDMAN_3551
MTJJ112_17395
MTUBMT7199_3280
MTUCJ113_22575
MTUEJ114_17360
MTXM943_16730
MTUHI917_22710
MTULTBHG_03174
MTUTHKBT1_3414
MTUUHKBT2_3421
MTQHKBS1_3424
MBOBQ2027_MB3266C
MBBBCG_3267c
MBTJTY_3263
MBMBCGMEX_3265c
MBKK60_033670
MBXBCGT_3104
MAFMAF_32490
MMICRN08_3574
MCEMCAN_32561
MCQBN44_70018
MCVBN43_60247
MCXBN42_41288
MCZBN45_60267
MORYMO_003384
MPAMAP_3351c
MAOMAP4_0433
MAVIRC58_02070
MAVURE97_02075
MAVMAV_4200
MITOCO_40590
MIAOCU_40500
MIDMIP_06116
MYOOEM_40840
MCHIAN480_21330
MIROCQ_41680
MMALCKJ54_19240
MLPMLM_3359
MMANMMAN_28640
MSAMycsm_00891
MULMUL_2574
MMIMMAR_1307
MMAEMMARE11_12730
MLIMULP_01475
MPSEMPSD_14880
MSHOMSHO_60010
MMCMmcs_3486
MKMMkms_3549
MJLMjls_3499
MMMW7S_20265
MKNMKAN_17270 MKAN_21360 MKAN_26235
MYEAB431_14970 AB431_23815
MHADB586_16210 B586_17385
MDXBTO20_12690
MFJMFLOJ_21760
MSTOMSTO_25450
MSIMMSIM_12780
MSAKMSAS_48630
MKUI2456_06665
MLWMJO58_06335
MXEMYXE_21180
MNVMNVI_44680
MPAGC0J29_07305 C0J29_19855
MNMMNVM_02870
MCOOMCOO_04590
MBAIMB901379_01199 MB901379_01267
MSEOMSEO_51380
MHEKJMUB5695_02124
MGAUMGALJ_53870
MLJMLAC_04730
MBRDMBRA_35960
MSHJMSHI_31610
MOTLTS72_22920
MKYIWGMT90018_13550
MWUPT015_03745
MVAMvan_2947
MCBMycch_1328 Mycch_3521 Mycch_4537
MFTXA26_51870
MLLB1R94_22935
MRHMycrhN_0795
MDUMDUV_32670
MMORMMOR_55040
MAICMAIC_09920 MAIC_26250
MALVMALV_27220
MPSCMPSYJ_49790
MGADMGAD_29030
MHEVMHEL_32930
MANYMANY_28770
MAUBMAUB_49450
MPHUMPHO_18500 MPHO_20060
MMUCC1S78_008370
MMATMMAGJ_25040
MBOKMBOE_02200
MFGK6L26_26775
MMONEWR22_18040
MHOLK3U96_11760
MSENK3U95_04890
MPAEK0O64_14365 K0O64_23430
MRFMJO55_07410
MCROMI149_15160 MI149_23840
MSTEMSTE_00408
MSAOMYCSP_21960
MJDJDM601_1602
MTER4434518_01507
MMINMMIN_32030
MHIBMHIB_10460
MVMMJO54_08885
NFANFA_22060
NFRERS450000_01892
NAHF5544_24690
NADNCTC11293_04517
RHARHA1_ro01652
ROPROP_13470
ROAPd630_LPD05789
RAVAAT18_06540
RRZCS378_21660
RKOJWS14_08435
ROZCBI38_01005
RPSKJWS13_37740
GRUGCWB2_16575
GOMD7316_00366
GAVC5O27_11580
GODGKZ92_15500
PEIH9L10_09760
TEDU5C87_03920
NANOG5V58_00045
APRECNX65_23240
AMIAmir_4657
ASEACPL_4161(nrm)
ACTSACWT_4032
ACTLL3i22_034560
PFLAPflav_015670
PSUUPsuf_003850
CATICS0771_47910
DVCDvina_22715
DAURDaura_16755
DMATDmats_18290
CYNCyan7425_2945
AMRAM1_2537
LEPLepto7376_1900
CYTcce_1858
CWACwatDRAFT_2846
CYPPCC8801_0005
CYHCyan8802_0003
TERTery_4814
RIVRiv7116_5563
ATMANT_03710
PSUBPelsub_P2210
OTEOter_4173
SLOMPXH66_06720
PSLPsta_4588
PIRVN12_16870
LCREPla8534_44360
AAGGETAA8_47830
BREMPSR63_05235
LPAVPLANPX_1065 PLANPX_3038 PLANPX_3920
AMUCPan181_19040 Pan181_48760
GIMF1728_06855
GPNPan110_15780
FTJFTUN_5779
ULIETAA1_48510
AGVOJF2_02720
HBSIPV69_21575
UAMUABAM_00293
SBUSpiBuddy_1553
ORPMOP44_00505
PFERIRI77_09965
ABACLuPra_00228 LuPra_03028
MSILMETEAL_26710
MCOSGM418_19870
MBASALGA_3412
NKONiako_4354
FGGFSB75_02485
PSEGD3H65_19065
PGINFRZ67_13885
PGOFSB84_13790
LACSH4075_21440
CMRCycma_1728
CAMUCA2015_1634
BBDBelba_1490
ALMAO498_02055
SLISlin_1791
SPIKEXU85_22930
RHOZGXP67_16175 GXP67_16205
RSIRunsl_1122
RUNDR864_14685
RUPDTQ70_24775
EOLEmtol_1108
ALSDJ013_21900
HYMN008_20490
HYJFHG12_03640
MTTFtrac_2288
FPFDCC35_02315
CLITOQ292_30005
CHKD4L85_22730
FBCFB2170_12981
MARTBTR34_01040
SPONHME9304_02016
PHGKCTC32516_00710
WINWPG_2355
SYISB49_15690
TENLPB136_11690
FEKC1H87_02435
PPONMUN68_011585
FLGLV716_06185
SABUMBM09_11355
FBEFF125_09180
IALIALB_2999
MROMROS_1124
CPRVCYPRO_2360
DDFDEFDS_1124
DAPDacet_1400
CNICalni_0912
FSIFlexsi_1539
NTIDNFV4_00758
NALLPP769_09240
NNEOPQG83_20545
MBAKMSBR3_0546
MACMA_2249
MMAMM_2869
MMAZMmTuc01_2941
MMJMSMAS_1849
MMACMSMAC_1270
MVCMSVAZ_2723
MEKMSKOL_2722
MLSMSLAZ_1867
METMMSMTP_1649
MEFMSWH1_1699
MEQMSWHS_1614
MSJMSSAC_2278
MSZMSSIH_1857
MSWMSSIT_1914
MHORMSHOH_1519
MMETMCMEM_1540
MELOJ7W08_04715
MMHMmah_1061
MHAZBHR79_08175
MEVMetev_0400
MZHMzhil_1200
MZIHWN40_06435
MHZMetho_0527
MCJMCON_0211 MCON_2076
MHIMhar_0676 Mhar_0677
HALQHrr1229_016730 Hrr1229_017875
LOKILokiarch_28780 Lokiarch_34420
 » show all
Reference
1  [PMID:25807229]
  Authors
Carrion O, Curson AR, Kumaresan D, Fu Y, Lang AS, Mercade E, Todd JD
  Title
A novel pathway producing dimethylsulphide in bacteria is widespread in soil environments.
  Journal
Nat Commun 6:6579 (2015)
DOI:10.1038/ncomms7579
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.334
IUBMB Enzyme Nomenclature: 2.1.1.334
ExPASy - ENZYME nomenclature database: 2.1.1.334
BRENDA, the Enzyme Database: 2.1.1.334

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