KEGG   ENZYME: 2.1.1.338Help
Entry
EC 2.1.1.338                Enzyme                                 

Name
desmethylxanthohumol 6'-O-methyltransferase;
OMT1 (ambiguous)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
desmethylxanthohumol [CPD:C16416]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
xanthohumol [CPD:C16417]
Comment
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
History
EC 2.1.1.338 created 2017
Pathway
ec00941  Flavonoid biosynthesis
Orthology
K21581  desmethylxanthohumol 6'-O-methyltransferase
Reference
1  [PMID:18223037]
  Authors
Nagel J, Culley LK, Lu Y, Liu E, Matthews PD, Stevens JF, Page JE
  Title
EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol.
  Journal
Plant Cell 20:186-200 (2008)
DOI:10.1105/tpc.107.055178
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.338
IUBMB Enzyme Nomenclature: 2.1.1.338
ExPASy - ENZYME nomenclature database: 2.1.1.338
BRENDA, the Enzyme Database: 2.1.1.338

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