KEGG ENZYME: 2.1.1.346

ENZYME: 2.1.1.346

Entry

EC 2.1.1.346                Enzyme

Name

U6 snRNA m6A methyltransferase;
METTL16 (gene name)

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:adenine in U6 snRNA methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + adenine in U6 snRNA = S-adenosyl-L-homocysteine + N6-methyladenine in U6 snRNA [RN:R11953]

Reaction(KEGG)

R11953

Substrate

S-adenosyl-L-methionine [CPD:C00019];
adenine in U6 snRNA [CPD:C21798]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
N6-methyladenine in U6 snRNA [CPD:C21799]

Comment

This enzyme, found in vertebrates, methylates a specific adenine in a hairpin structure of snRNA. The effects of the binding of the methyltransferase to its substrate is important for the regulation of the activity of an isoform of EC 2.5.1.6, methionine adenosyltransferase, that produces S-adenosyl-L-methionine [1,2]. The enzyme also binds (and maybe methylates) the lncRNAs XIST and MALAT1 as well as a number of pre-mRNAs at specific positions often found in the intronic regions [2].

History

EC 2.1.1.346 created 2018

Orthology

K11393

U6 snRNA m6A methyltransferase

Genes

HSA:	79066(METTL16)

PTR:	468142(METTL16)

PPS:	100985777(METTL16)

GGO:	101136835(METTL16)

PON:	100432341(METTL16)

NLE:	100588460(METTL16)

HMH:	116458442(METTL16)

MCC:	721312(METTL16)

MCF:	102126585(METTL16)

MTHB:

126938863

MNI:	105474302(METTL16)

CSAB:

103242135(METTL16)

CATY:

105584038(METTL16)

PANU:

101025110(METTL16)

TGE:	112609893(METTL16)

MLEU:

105544686(METTL16)

RRO:	104682018(METTL16)

RBB:	108526344(METTL16)

TFN:	117067927(METTL16)

PTEH:

111521382(METTL16)

CANG:

105522009(METTL16)

CJC:	100394235(METTL16)

SBQ:	101040153(METTL16)

CIMI:

108313297(METTL16)

CSYR:

103260578(METTL16)

MMUR:

105857981(METTL16)

LCAT:

123620670(METTL16)

PCOQ:

105817373(METTL16)

OGA:	100951183(METTL16)

MMU:	67493(Mettl16)

MCAL:

110304744(Mettl16)

MPAH:

110331579(Mettl16)

MCOC:

116078078(Mettl16)

ANU:	117711581(Mettl16)

MUN:	110551483(Mettl16) 110558711

CGE:	100765063(Mettl16)

MAUA:

101829415(Mettl16)

PROB:

127218920(Mettl16)

PLEU:

114691415(Mettl16)

MORG:

121456621(Mettl16)

MFOT:

126492449

AAMP:

119812021(Mettl16)

NGI:	103730532(Mettl16)

HGL:	101709207(Mettl16)

CPOC:

100734997(Mettl16)

CCAN:

109685289(Mettl16)

DORD:

105985682(Mettl16)

DSP:	122103374(Mettl16)

PLOP:

125365360(Mettl16)

NCAR:

124980743

OCU:

100354377

OPI:	101529808(METTL16)

TUP:	102500444(METTL16)

GVR:	103584899(METTL16) 103590444

CFA:	480655(METTL16)

CLUD:

112677543(METTL16)

VVP:	112933136(METTL16)

VLG:	121474145(METTL16)

NPO:	129509491(METTL16)

AML:	100479575(METTL16)

UMR:	103667151(METTL16)

UAH:	113269143(METTL16)

UAR:	123776841(METTL16)

ELK:

111151376

LLV:

125087822

MPUF:

101670495(METTL16)

MNP:	132003176(METTL16)

NVS:	122906329(METTL16)

ORO:	101368257(METTL16)

EJU:	114213998(METTL16)

ZCA:	113939559(METTL16)

MLX:	118025196(METTL16)

NSU:

110592874

LWW:	102730357 102730660

FCA:	101098176(METTL16)

PYU:	121017336(METTL16)

PCOO:

112854151(METTL16)

PBG:	122485099(METTL16)

LRUF:

124512990

PTG:	102953476(METTL16)

PPAD:

109255176(METTL16)

PUC:

125926886

AJU:

106983218

HHV:	120244873(METTL16)

BTA:	509278(METTL16)

BOM:	102269245(METTL16)

BIU:	109573961(METTL16)

BBUB:

102415457(METTL16)

BBIS:

105003884(METTL16)

CHX:	102181233(METTL16)

OAS:	101118885(METTL16)

BTAX:

128052858 128057123 128065030(METTL16)

ODA:	120866207(METTL16)

CCAD:

122447430(METTL16)

MBEZ:

129541562(METTL16)

SSC:	100512985(METTL16)

CFR:	102517540(METTL16)

CBAI:

105071497(METTL16)

CDK:	105094394(METTL16)

VPC:	102524731(METTL16)

BACU:

103018670(METTL16)

LVE:	103079111(METTL16)

OOR:	101277494(METTL16)

DLE:	111185691(METTL16)

PCAD:

102980728(METTL16)

PSIU:

116745499(METTL16)

NASI:

112393440(METTL16)

ECB:	100060313(METTL16)

EPZ:	103554989(METTL16)

EAI:	106822016(METTL16)

MYB:	102245762(METTL16)

MYD:	102763524(METTL16)

MMYO:

118671926(METTL16)

MLF:	102432877(METTL16)

MNA:	107535629(METTL16)

PKL:	118702505(METTL16)

EFUS:

103291782(METTL16)

HAI:	109386913(METTL16)

DRO:	112308453(METTL16)

SHON:

119003680(METTL16)

AJM:	119040680(METTL16)

PDIC:

114503053(METTL16)

PHAS:

123817040(METTL16)

MMF:	118634690(METTL16)

RFQ:	117013310(METTL16)

PALE:

102893627(METTL16)

PGIG:

120621061(METTL16)

PVP:	105291837(METTL16)

RAY:	107507706(METTL16)

MJV:	108385927(METTL16)

TOD:	119230470(METTL16)

SARA:

101536921(METTL16)

LAV:	100667422(METTL16)

TMU:

101359623

ETF:	101639019(METTL16)

MDO:	100013253(METTL16)

GAS:	123244469(METTL16)

SHR:	100929591(METTL16)

AFZ:

127558818

PCW:	110222082(METTL16)

OAA:	100078226(METTL16)

GGA:	431184(METTL16)

PCOC:

116242295(METTL16)

MGP:

100544219

CJO:	107319635(METTL16)

TPAI:

128072310(METTL16)

LMUT:

125691774(METTL16)

NMEL:

110399133(METTL16)

APLA:

101799964(METTL16)

ACYG:

125179960(METTL16)

CATA:

118245073(METTL16)

AFUL:

116502055(METTL16)

TGU:	100224599(METTL16)

LSR:	110480767(METTL16)

SCAN:

103827124(METTL16)

PMOA:

120506461(METTL16)

OTC:	121339304(METTL16)

PRUF:

121351679(METTL16)

GFR:	102035966(METTL16)

FAB:	101821499(METTL16)

OMA:	130254760(METTL16)

PHI:	102104214(METTL16)

PMAJ:

107213548(METTL16)

CCAE:

111938740 111942600

CCW:	104687188(METTL16)

CBRC:

103613875(METTL16)

ETL:	114062564(METTL16)

ZAB:	102065399(METTL16)

ACHL:

103798466(METTL16)

SVG:	106860846(METTL16)

MMEA:

130585552(METTL16)

HRT:	120748596(METTL16)

FPG:	101917549(METTL16)

FCH:	102058069(METTL16)

CLV:	102083907(METTL16)

EGZ:	104126569(METTL16)

NNI:	104008661(METTL16)

PCRI:

104024001(METTL16)

PLET:

104622039(METTL16)

EHS:

104505578

PCAO:

104050420(METTL16)

ACUN:

113480566(METTL16)

TALA:

104355567(METTL16)

PADL:

103922188(METTL16)

AFOR:

103905475(METTL16)

ACHC:

115343907(METTL16)

HALD:

104310778(METTL16)

HLE:	104831720(METTL16)

AGEN:

126049016

GCL:

127018547

CCRI:

104158920(METTL16)

CSTI:

104549218

CMAC:

104473228(METTL16)

MUI:	104534381(METTL16)

BREG:

104629238(METTL16)

FGA:

104071610

GSTE:

104250636(METTL16)

LDI:

104340122

MNB:	103774934(METTL16)

OHA:	104335971(METTL16)

NNT:	104410268(METTL16)

SHAB:

115601686(METTL16)

DPUB:

104305659(METTL16)

PGUU:

104464624(METTL16)

ACAR:

104525406(METTL16)

CPEA:

104387709(METTL16)

AVIT:

104267063(METTL16)

CVF:	104281882(METTL16)

RTD:	128912343(METTL16)

CUCA:

104055822(METTL16)

BRHI:

104487881(METTL16)

AAM:	106497249(METTL16)

NPD:	112956853(METTL16)

TGT:	104578730(METTL16)

SCAM:

104153687(METTL16)

ASN:	102379059(METTL16)

AMJ:	102560118(METTL16)

CPOO:

109319186(METTL16)

GGN:	109304704(METTL16)

PSS:	102445105(METTL16)

CMY:	102934705(METTL16)

CCAY:

125621886(METTL16)

DCC:	119843267(METTL16)

CPIC:

101940016(METTL16)

TST:	117886467(METTL16)

CABI:

116820862(METTL16)

MRV:	120400403(METTL16)

ACS:	100561572(mettl16)

PVT:	110088992(METTL16)

SUND:

121935449(METTL16)

PBI:	103059496(METTL16)

PMUR:

107303009(METTL16)

CTIG:

120315183(METTL16)

TSR:	106554152(METTL16)

PGUT:

117664720(METTL16)

APRI:

131198901(METTL16)

PTEX:

113447836(METTL16)

NSS:	113422068(METTL16)

VKO:	123031825(METTL16)

PMUA:

114582238(METTL16)

PRAF:

128399867(METTL16)

ZVI:	118094428(METTL16)

HCG:	128346027(METTL16)

GJA:	107121598(METTL16)

STOW:

125436625(METTL16)

EMC:	129345808(METTL16)

XLA:	108709350 443759(mettl16.L)

XTR:	100170444(mettl16)

NPR:	108785099(METTL16)

RTEM:

120927637(METTL16)

BBUF:

120994719(METTL16)

BGAR:

122932496(METTL16)

MUO:	115456671(METTL16)

GSH:	117349323(METTL16)

DRE:	445217(mettl16)

SRX:	107743666 107744784

SANH:

107664944

SGH:

107585611

CCAR:

109058035(mettl16) 109067099 109084010

CAUA:

113115019

CGIB:

127972892

PTET:

122326836

LROH:

127176803(mettl16)

OMC:	131554025(mettl16)

PPRM:

120478874(mettl16)

MAMB:

125248751(mettl16)

CIDE:

127495967

MASI:

127422315 127430270

TROS:

130564659(mettl16)

MANU:

129438070(mettl16)

IPU:

108277677

IFU:	128621619(mettl16)

PHYP:

113532552(mettl16)

SMEO:

124394684(mettl16)

TFD:	113643769(mettl16)

AMEX:

103028752(mettl16)

CMAO:

118801517(mettl16)

EEE:	113569750(mettl16)

CHAR:

105898224(mettl16)

TRU:	101062099(mettl16)

TFS:	130535056(mettl16)

TNG:	GSTEN00033357G001

LCO:	104935454(mettl16)

NCC:	104967203(mettl16)

CGOB:

115017956(mettl16)

ELY:	117259408(mettl16)

EFO:	125888673(mettl16)

PLEP:

121943521(mettl16)

SLUC:

116048313(mettl16)

ECRA:

117941740(mettl16)

ESP:	116677353(mettl16)

PFLV:

114552438(mettl16)

GAT:	120826703(mettl16)

PPUG:

119218599(mettl16)

AFB:	129091866(mettl16)

CLUM:

117741640(mettl16)

MSAM:

119883414(mettl16)

SCHU:

122878810(mettl16)

CUD:	121516304(mettl16)

ALAT:

119011654(mettl16)

MZE:	101474733(mettl16)

ONL:	100695707(mettl16)

OAU:	116315193(mettl16)

OLA:	101169471(mettl16)

OML:	112149898(mettl16)

XMA:	102232539(mettl16)

XCO:	114133391(mettl16)

XHE:	116708147(mettl16)

PRET:

103474551(mettl16)

PFOR:

103155190(mettl16)

PLAI:

106957252(mettl16)

PMEI:

106927285(mettl16)

GAF:	122833170(mettl16)

CVG:	107103570(mettl16) 107103989

CTUL:

119782803(mettl16)

GMU:	124883746(mettl16)

NFU:	107380377(mettl16)

KMR:	108246060(mettl16)

ALIM:

106515476(mettl16)

NWH:	119410587(mettl16)

AOCE:

111573002(mettl16)

MCEP:

125013973(mettl16)

CSEM:

103378477(mettl16)

POV:	109630391(mettl16)

SSEN:

122773745(mettl16)

HHIP:

117772515(mettl16)

HSP:	118106514(mettl16)

LCF:

108890382

SDU:	111238017(mettl16)

SLAL:

111653420(mettl16)

XGL:	120792465(mettl16)

HCQ:	109525371 109525404(mettl16)

SSCV:

125972105

BPEC:

110154120(mettl16)

MALB:

109960183(mettl16)

BSPL:

114867502(mettl16)

SASA:

100195164(mettl16)

STRU:

115206286(mettl16)

OTW:

112267042

OMY:

110503873

OGO:

124005289

ONE:	115141778(mettl16)

OKI:	109875612(mettl16)

OKE:

118394745

SALP:

111959225(mettl16)

SNH:	120018221 120028973(mettl16)

CCLU:

121566331 121567912

ELS:	105005717(mettl16)

SFM:	108921289(mettl16)

PKI:	111852900(mettl16)

AANG:

118234918(mettl16)

LOC:	102697714(mettl16)

PSPA:

121308682(mettl16)

ARUT:

117429870 117430782

PSEX:

120531485(mettl16)

LCM:	102357476(METTL16)

CMK:	103183305(mettl16)

RTP:	109915373(mettl16)

CPLA:

122563955(mettl16)

LERI:

129710533(mettl16)

BFO:

118426728

BBEL:

109463429

SCLV:

120336691 120341264

SPU:	115918828 588854

LPIC:

129254680

APLC:

110982293

AJC:

117118759

SKO:

100375111

DME:	Dmel_CG7544(CG7544)

DER:

6548994

DSE:

6609249

DSI:	Dsimw501_GD11099(Dsim_GD11099)

DYA:	Dyak_GE13632

DAN:

6495163

DSR:

110177681

DPO:

4804015

DPE:

6590543

DMN:

108158198

DWI:

6639760

DGR:

6561347

DMO:	Dmoj_GI18716

DAZ:

108615824

DNV:

115564616

DHE:

111602555

DVI:

6626490

CCAT:

101450250

BOD:

106621395

RZE:	108364773 108367852

TDA:

119680699

MDE:

101892334

SCAC:

106082350

LCQ:

111680035

LSQ:

119611533

ECOE:

129940341

HIS:

119661463

AGA:	AgaP_AGAP011889

ACOZ:

120955374

AARA:

120901475

AMER:

121598652

ASTE:

118504839

AFUN:

125770194

AALI:

118462733

AAG:

5571925

AALB:

109410613 109410722

CQU:	CpipJ_CPIJ012620 CpipJ_CPIJ015643

CPII:

120420336

CNS:

116337892

BCOO:

119066908

AME:

552510

ACER:

107998128

ALAB:

122712223

ADR:

102681861

AFLR:

100865169

BIM:

100746437

BBIF:

117209209

BVK:

117239531

BVAN:

117165875

BTER:

100644922

BAFF:

126916318

BPYO:

122565928

FVI:

122532956

CCAL:

108625270

OBB:

114879372

MGEN:

117217881

NMEA:

116432072

CGIG:

122398540

SOC:

105199230

MPHA:

105836936

AEC:

105144290

ACEP:

105619207

PBAR:

105433112

VEM:

105558905

HST:

105183808

DQU:

106744101

CFO:

105251370

FEX:

115242323

LHU:

105670136

PGC:

109854953

OBO:

105283767

PCF:

106792967

PFUC:

122520048

VPS:

122631774

VCRB:

124426962

NVI:

100123669

CSOL:

105368924

TPRE:

106655576

LHT:

122505272

LBD:

127281040

MDL:	103574787 106694290

CGLO:

123266173

FAS:

105269043

DAM:

107036703

AGIF:

122857209

VCAN:

122409565

CCIN:

107268788

DSM:

124410626

NPT:

124220221

NFB:

124183492

NLO:

107227302

NVG:

124305931

TCA:

661821

DPA:

109540451

SOY:

115884915

AGRG:

126735577

ATD:

109598942

CSET:

123313863

AGB:

108912949

LDC:

111505005

NVL:

108562140

APLN:

108742476

PPYR:

116181369

OTU:

111425792

BMOR:

101744195

BMAN:

114249898

MSEX:

115445230

DPL:	KGM_207769

BANY:

112046226

MJU:

123872774

NIQ:

126773980

VCD:

124534390

MCIX:

123656299

PMAC:

106717726

PPOT:

106108468

PXU:

106115835

PRAP:

110995152

PBX:

123710208

PNAP:

125049096

ZCE:

119830802

CCRC:

123695950

LSIN:

126975967

HAW:

110372866

HZE:

124637796

TNL:

113499038

SLIU:

111365053

OFU:

114360958

PXY:

105387479

PGW:

126371867

CCRN:

123295083

API:

100168380

DNX:

107171844

AGS:

114120252

RMD:

113550631

ACOO:

126845557

BTAB:

109034206

DCI:

103516521

CLEC:

106669960

HHAL:

106691140

NLU:

111049543

HVI:	124367329 124367395 124367429 124371885 124372833

PHU:	Phum_PHUM438210

FOC:

113203902

TPAL:

117645459

ZNE:

110837239

CSEC:

111866269

IEL:

124158607

FCD:

110852948

DPX:	DAPPUDRAFT_50570

PVM:	113811444 113811458

PJA:

122267067

PCHN:

125036737

PMOO:

119592629

HAME:

121872293

PCLA:

123772872

PTRU:

123513720

HAZT:

108680475

EAF:

111709284

LSM:

121118055

PPOI:

119092843 119092848

DSV:

119445610

RSAN:

119376011 119390515

RMP:

119170013

VDE:

111252059

VJA:

111271195

TUT:

107371698

DPTE:

113797178

DFR:

124497197

CSCU:

111642630

PTEP:

107440288

UDV:

129220959

SDM:

118189118

LPOL:

106457531

PMEO:

129592212

CEL:	CELE_ZK1128.2(mett-10)

CBR:	CBG_09879(Cbr-mett-10)

CRQ:	GCK72_009596

NAI:	NECAME_02035

BMY:	BM_BM7633(Bma-mett-10)

LOA:	LOAG_01952

TSP:	Tsp_01507 Tsp_12275

HRO:	HELRODRAFT_194040

LGI:	LOTGIDRAFT_121844

PCAN:

112561775

BGT:

106068367

GAE:

121389997

HRF:

124132071

HRJ:

124254187

CRG:

105347004

CVN:

111133822

CANU:

128186997

OED:

125674577

MYI:

110455566

PMAX:

117333072

MMER:

123533929

DPOL:

127868342

OBI:

106869560

OSN:

115224468

LAK:

106154003

SMM:	Smp_129140.1

SHX:	MS3_00005337(METTL16)

OVI:	T265_01188

EGL:

EGR_05066

NVE:

5507281

EPA:

110233634

ATEN:

116304784

ADF:

107354373

AMIL:

114966831

PDAM:

113685660

SPIS:

111339945

DGT:	114520431 114538261

XEN:

124434517

HMG:

100201906

HSY:

130623306

TAD:	TRIADDRAFT_28751

AQU:

100631625

ATH:	AT2G21070(FIO1)

ALY:

9314600

CRB:	17888846 17892947

CSAT:

104702653 104713551 104751764

EUS:	EUTSA_v10000146mg

BRP:

103864244

BNA:	106420602 106420607

BOE:

106337314

RSZ:

108849697

THJ:

104807791

CPAP:

110816590

CIT:

102612205

CIC:	CICLE_v10028267mg

PVY:

116131100

MINC:

123228120

TCC:

18607582

GRA:

105762922

GHI:	107932657 107945042

GAB:

108476494

DZI:

111308762

EGR:

104453416

GMX:	100802073 100819552

GSJ:	114412695 114421505

PVU:	PHAVU_002G189600g

VRA:	106765472 106768963

VAR:

108319107

VUN:

114177723

CCAJ:

109812802

APRC:

113857587

MTR:

112421092

TPRA:

123918743

CAM:	101510943 101511570

PSAT:

127105758

LJA:	Lj4g3v0217740.1(Lj4g3v0217740.1)

ADU:

107481620

AIP:

107631485

AHF:	112734636 112792420

LANG:

109359826

PCIN:

129292150

FVE:

101304449

RCN:

112172166

PPER:

18767317

PMUM:

103334800

PAVI:

110753721

PDUL:

117612162

MDM:

103409315

MSYL:

126623226

PXB:	103932385 103932395

ZJU:

107427563

MNT:

21407692

CSAV:

115704514

CSV:

101205279

CMO:

103490299

BHJ:

120077072

MCHA:

111007785 111022944

CMAX:

111468473

CMOS:

111455141

CPEP:

111811582

RCU:

8265345

JCU:

105650305

HBR:

110673417

MESC:

110607518

POP:

7470383

PEU:

105109101

PALZ:

118040472

JRE:

109006580

CILL:

122314388

CAVE:

132167968

QLO:

115969591

TWL:

120011892

VVI:

100247029

VRI:

117911072

SLY:

101254840

SPEN:

107008552

SOT:	102594731 102601562

SSTN:

125861597

CANN:

107839524

LBB:

132645187

NTA:	107785301 107785444 107807777

NSY:	104229034 104234132

NTO:

104111976

NAU:	109212298 109226024

INI:	109160032 109173465

ITR:	116003834 116028928

SIND:

105169769

OEU:

111380735

EGT:

105957750

SSPL:

121749702 121752381

SMIL:

130989331

APAN:

127262307

HAN:

110921632

ECAD:

122585743

LSV:

111898983

CCAV:

112525712

DCR:

108196683

CSIN:

114257962 114283336

RVL:

131308320

AEW:

130779054

BVG:

104903954

SOE:

110786532

CQI:	110718560 110739526

ATRI:

130805221 130805702

MOF:

131156715

NNU:

104593486

MING:

122085403

TSS:	122648798 122663704

PSOM:

113290514

OSA:

4328120

DOSA:

Os02t0121200-01(Os02g0121200)

OBR:

102710182

OGL:

127762778

BDI:

100835129

ATS:

109766444

TDC:	119314521 119325488

TAES:

123131893 123135878 123143395

TUA:

125516062

LPER:

127308694

LRD:	124686083 124686320

SBI:

8068259

ZMA:

100275693

SITA:

101782727

SVS:

117864922

PVIR:

120654471 120702680

PHAI:

112877496

PDA:

103706342

EGU:

105055058

MUS:

103973364

ZOF:	122042649 122047154

DCT:

110095485

PEQ:

110037379

AOF:

109819811

NCOL:

116260499

ATR:

18441638

SMO:	SELMODRAFT_110877 SELMODRAFT_443646

PPP:

112285489

CRE:	CHLRE_01g044150v5

MNG:

MNEG_7697

CSL:	COCSUDRAFT_53530

APRO:

F751_5074

OLU:	OSTLU_4809

OTA:	OT_ostta12g02050

MIS:	MICPUN_113202(MET10)

MPP:	MICPUCDRAFT_49964

AGO:	AGOS_AAR189C

ERC:

Ecym_6027

PPA:	PAS_chr4_0027

PGU:	PGUG_02662

YLI:	YALI0D10329g

SLB:	AWJ20_2950

BNN:	FOA43_002320

BBRX:

BRETT_005110

OPA:	HPODL_02035

NCR:

NCU11362

NTE:	NEUTE1DRAFT144835(NEUTE1DRAFT_144835)

SMP:	SMAC_09439

PAN:	PODANSg6041

TTT:	THITE_2116145

MTM:	MYCTH_2299692

MGR:

MGG_09820

PPEI:

PpBr36_04004

PGRI:

PgNI_12473

TMN:	UCRPA7_694

SSCK:

SPSK_07417

FGR:	FGSG_04198

FPU:	FPSE_10402

FPOA:

FPOAC1_006649

FVN:	FVRRES_07262

FVR:	FVEG_10386

FOX:	FOXG_20534

NHE:	NECHADRAFT_44289

FFC:	NCS54_00804300

FMU:	J7337_011661

TRE:	TRIREDRAFT_39285

TRR:	M419DRAFT_106028

MAW:

MAC_04269

MAJ:

MAA_02785

PCHM:

VFPPC_07169

CMT:

CCM_03996

AMUS:

LMH87_009227

PLJ:	VFPFJ_08810

PTKZ:

JDV02_006566

VAL:	VDBG_08418

VDA:	VDAG_08081

CFJ:	CFIO01_03901

CLUP:

CLUP02_15739

CHIG:

CH63R_05184

SAPO:

SAPIO_CDS1502

ELA:	UCREL1_7286

PFY:	PFICI_12837

BFU:	BCIN_12g05310

MBE:

MBM_00697

PSCO:

LY89DRAFT_617710

GLZ:	GLAREA_09615

ANI:

AN6713.2

AFM:	AFUA_7G05590

ACT:	ACLA_007350

NFI:	NFIA_026840

ANG:	An07g02250

AFV:	AFLA_003222

ALUC:

AKAW2_11930A

ACHE:

ACHE_60967A

APUU:

APUU_70243S

PCS:	Pc12g06780

PDP:	PDIP_54270

POU:	POX_a00723

TMF:	EYB26_007383

TRG:	TRUGW13939_06975

CIM:	CIMG_05470

CPW:	CPC735_066140

URE:	UREG_06255

PBL:	PAAG_00036

PBN:	PADG_07222

ABE:

ARB_00675

TVE:

TRV_05018

PNO:	SNOG_05851

PTE:

PTT_11931

BZE:	COCCADRAFT_9081

BSC:	COCSADRAFT_38221

BOR:	COCMIDRAFT_30632

AALT:

CC77DRAFT_168121

ARAB:

EKO05_0000659

ZTR:	MYCGRDRAFT_24632

PFJ:	MYCFIDRAFT_41101

FFU:	CLAFUR5_03549

CBET:

CB0940_03168

BCOM:

BAUCODRAFT_70727

TML:	GSTUM_00002139001

SPO:	SPAC27D7.08c

SOM:	SOMG_03735(mtl16)

CNE:

CNC04020

CNB:

CNBC3160

CNG:	CNAG_02784

CGI:	CGB_C6130W

TMS:	TREMEDRAFT_30662

TASA:

A1Q1_06990

CCAC:

CcaHIS019_0400910(CcaverHIS019_0400910)

PPL:	POSPLDRAFT_28036

TVS:	TRAVEDRAFT_60998

DSQ:	DICSQDRAFT_108620

PCO:	PHACADRAFT_258520

SHS:	STEHIDRAFT_126591

HIR:	HETIRDRAFT_478853

PSQ:	PUNSTDRAFT_91935

ADL:	AURDEDRAFT_176350

FME:	FOMMEDRAFT_153997

GTR:	GLOTRDRAFT_123633

RSX:	RhiXN_06608

MRR:	Moror_16301

E1B28_010995

SCM:	SCHCO_02639553(SCHCODRAFT_02639553)

CPUT:

CONPUDRAFT_169696

WSE:	WALSEDRAFT_60716

SGRA:

EX895_001363

MGL:

MGL_0651

MRT:

MRET_2521

PGR:	PGTG_12226

PTRC:

PtA15_4A304

MLR:	MELLADRAFT_74344

MBR:	MONBRDRAFT_27301

SRE:	PTSG_06103

DDI:	DDB_G0275203

DPP:	DICPUDRAFT_25940 DICPUDRAFT_78256

DFA:

DFA_04208

ACAN:

ACA1_142640

TPS:	THAPSDRAFT_11744

PIF:	PITG_06794

PSOJ:

PHYSODRAFT_486208

SPAR:

SPRG_09490

» show all

Reference

1 [PMID:28525753]

Authors

Pendleton KE, Chen B, Liu K, Hunter OV, Xie Y, Tu BP, Conrad NK

Title

The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention.

Journal

Cell 169:824-835.e14 (2017)
DOI:10.1016/j.cell.2017.05.003

Sequence

[hsa:79066]

Reference

2 [PMID:29051200]

Authors

Warda AS, Kretschmer J, Hackert P, Lenz C, Urlaub H, Hobartner C, Sloan KE, Bohnsack MT

Title

Human METTL16 is a N(6)-methyladenosine (m(6)A) methyltransferase that targets pre-mRNAs and various non-coding RNAs.

Journal

EMBO Rep 18:2004-2014 (2017)
DOI:10.15252/embr.201744940

Sequence

[hsa:79066]

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.346

IUBMB Enzyme Nomenclature:

2.1.1.346

ExPASy - ENZYME nomenclature database:

2.1.1.346

BRENDA, the Enzyme Database:

2.1.1.346

DBGET integrated database retrieval system