KEGG   ENZYME: 2.1.1.355Help
Entry
EC 2.1.1.355                Enzyme                                 

Name
[histone H3]-lysine9 N-trimethyltransferase;
KMT1A (gene name);
KMT1B (gene name);
KMT1C (gene name);
KMT1D (gene name);
KMT1E (gene name);
KMT1F (gene name);
MT8 (gene name);
SUV39H1 (gene name);
G9A (gene name);
EHMT1 (gene name);
PRDM2 (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:[histone H3]-L-lysine9 N6-methyltransferase
Reaction(IUBMB)
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine9 = 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9 (overall reaction);
(1a) S-adenosyl-L-methionine + a [histone H3]-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine9;
(1b) S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine9;
(1c) S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9 = S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
[histone H3]-L-lysine9;
[histone H3]-N6-methyl-L-lysine9;
[histone H3]-N6,N6-dimethyl-L-lysine9
Product
S-adenosyl-L-homocysteine [CPD:C00021];
[histone H3]-N6,N6,N6-trimethyl-L-lysine9;
[histone H3]-N6-methyl-L-lysine9;
[histone H3]-N6,N6-dimethyl-L-lysine9
Comment
This entry describes several enzymes that successively methylate the L-lysine9 residue of histone H3 (H3K9), ultimately generating a trimethylated form. These modifications influence the binding of chromatin-associated proteins. In general, the methylation of H3K9 leads to transcriptional repression of the affected target genes.
History
EC 2.1.1.355 created 1976 as EC 2.1.1.43, modified 1982, modified 1983, part transferred 2019 to EC 2.1.1.355
Pathway
ec00310  Lysine degradation
ec01100  Metabolic pathways
Orthology
K11419  [histone H3]-lysine9 N-trimethyltransferase SUV39H
K11420  [histone H3]-lysine9 N-trimethyltransferase EHMT
K11421  [histone H3]-lysine9 N-trimethyltransferase SETDB1
K11432  [histone H3]-lysine9 N-trimethyltransferase PRDM2
K18494  [histone H3]-lysine9 N-trimethyltransferase SETDB2
Genes
HSA: 10919(EHMT2) 6839(SUV39H1) 7799(PRDM2) 79723(SUV39H2) 79813(EHMT1) 83852(SETDB2) 9869(SETDB1)
PTR: 107971148(SUV39H1) 452719(SETDB2) 462572(EHMT2) 464891(EHMT1) 466014(SUV39H2) 469125(PRDM2) 469481(SETDB1)
PPS: 100968253(EHMT1) 100972839(SETDB1) 100977497(SUV39H1) 100982469(SUV39H2) 100986951(SETDB2) 100991724(EHMT2) 103782930(PRDM2)
GGO: 101125370(PRDM2) 101126338(SUV39H2) 101139808(EHMT2) 101141713(SETDB2) 101146215(SETDB1) 101146540(SUV39H1) 101151843(EHMT1)
PON: 100172621(SUV39H1) 100431310(SETDB1) 100436926(SUV39H2) 100436958(PRDM2) 100437576(SETDB2) 100449422(EHMT1) 100460372(EHMT2)
NLE: 100581330(SETDB1) 100582767(PRDM2) 100584465(EHMT1) 100591032(SUV39H2) 100593118 100598636(SUV39H1) 100606578(EHMT2) 115834394
MCC: 697378(SUV39H2) 706277(SETDB2) 711040(SUV39H1) 715824(EHMT2) 716141(SETDB1) 716295(PRDM2) 721470(EHMT1)
MCF: 101926557(PRDM2) 102117410(SETDB1) 102124788(SETDB2) 102125769(EHMT1) 102134179(SUV39H1) 102136014(SUV39H2) 102139754(EHMT2)
CSAB: 103214423(SETDB2) 103221737(EHMT2) 103225565(PRDM2) 103231938(SUV39H1) 103237926(SUV39H2) 103239544(EHMT1) 103241360 103247223(SETDB1)
RRO: 104660660(SUV39H1) 104662745(SETDB2) 104664471(SUV39H2) 104669606(EHMT1) 104674046(PRDM2) 104678126(EHMT2) 104681064(SETDB1)
RBB: 108517467(SUV39H1) 108519969 108520267(EHMT2) 108530731(SETDB2) 108531071(SUV39H2) 108533259(SETDB1) 108542880(EHMT1)
CJC: 100385110(PRDM2) 100394788(SETDB2) 100398057(EHMT1) 100401369(SUV39H1) 100401513(SUV39H2) 100408867(EHMT2) 100411734(SETDB1)
SBQ: 101040475(SUV39H2) 101042658(SETDB1) 101043411(SETDB2) 101046305(EHMT2) 101052197(SUV39H1) 101054202(PRDM2) 101054241(EHMT1)
MMU: 107303348(Gm45935) 110147(Ehmt2) 110593(Prdm2) 20937(Suv39h1) 239122(Setdb2) 64707(Suv39h2) 77683(Ehmt1) 84505(Setdb1)
MCAL: 110284133(Ehmt2) 110287176(Suv39h1) 110289296(Suv39h2) 110291522(Setdb1) 110293588(Prdm2) 110309030(Setdb2) 110312405(Ehmt1)
MPAH: 110313347(Suv39h1) 110317691(Ehmt1) 110320737(Setdb1) 110322886(Prdm2) 110325326(Setdb2) 110333642(Suv39h2) 110335935(Ehmt2)
RNO: 100361710(Setdb2) 302553(Suv39h1) 313678(Prdm2) 361798(Ehmt2) 362078(Ehmt1) 364785(Suv39h2) 689883(Setdb1)
MUN: 110540015(Setdb2) 110544320 110554698(Suv39h2) 110556467(Prdm2) 110560108(Ehmt2) 110560774(Setdb1) 110561991(Suv39h1) 110565135 110565136 110565639(Ehmt1)
CGE: 100754544(Ehmt1) 100755145(Suv39h2) 100764568(Suv39h1) 100765697(Setdb1) 100769417(Ehmt2) 100773277(Prdm2) 100774155 107979496
NGI: 103724422(Ehmt2) 103727170(Setdb2) 103730089(Setdb1) 103732609(Ehmt1) 103735184(Suv39h2) 103741644(Suv39h1) 103749132 103752332(Prdm2)
HGL: 101696702(Setdb2) 101697232(Ehmt2) 101699104(Ehmt1) 101699822(Prdm2) 101701917(Suv39h2) 101706867(Suv39h1) 101715248(Setdb1)
CCAN: 109681205(Setdb1) 109688969(Ehmt1) 109689573(Ehmt2) 109691104(Setdb2) 109691500(Suv39h2) 109701207(Suv39h1) 109702677(Prdm2)
OCU: 100342335(PHF11) 100348361(EHMT1) 100354725(SUV39H1) 100355131(EHMT2) 100355877(SETDB1) 100358024(SUV39H2) 103352508(PRDM2)
TUP: 102468719(SUV39H1) 102472765 102479735(EHMT2) 102495109(SUV39H2) 102498729(EHMT1) 102499550(PRDM2) 102502264(SETDB1) 102503290(SETDB2)
CFA: 100688431(PRDM2) 474851(EHMT2) 477995(SUV39H2) 483186(SETDB1) 485441(SETDB2) 491224(EHMT1) 491868(SUV39H1)
VVP: 112907242(SUV39H1) 112907769(SETDB1) 112911417(EHMT1) 112913622(EHMT2) 112929764(PRDM2) 112933120(SUV39H2) 112933943(SETDB2)
AML: 100466861(EHMT1) 100468794(EHMT2) 100469547(SUV39H2) 100472595(SUV39H1) 100476962(SETDB2) 100481446(PRDM2) 100482250(SETDB1)
UMR: 103664189(SUV39H2) 103666633(PRDM2) 103667532(SETDB1) 103669105(SUV39H1) 103675323(EHMT1) 103677615(SETDB2) 103682289(EHMT2)
UAH: 113241391(SUV39H2) 113243735(EHMT2) 113246155(SETDB1) 113248390 113248430 113251315 113265922(SUV39H1) 113270485(PRDM2)
ORO: 101364966(PRDM2) 101372094(SETDB1) 101374258(SUV39H2) 101375740(EHMT1) 101376988(EHMT2) 101381146(SUV39H1) 101381937(SETDB2)
FCA: 101082169(PRDM2) 101083571(SUV39H1) 101087111(EHMT1) 101091940(EHMT2) 101094118(SETDB1) 101099218(SUV39H2)
PTG: 102950897(SUV39H1) 102954489(EHMT1) 102962904(SETDB2) 102963752(SUV39H2) 102967892(PRDM2) 102968259(EHMT2) 102970727(SETDB1)
PPAD: 109248069(SUV39H1) 109257028(SETDB1) 109260239(EHMT1) 109260503(EHMT2) 109265964 109273698(SUV39H2) 109274376(PRDM2)
AJU: 106970864(SUV39H1) 106971016(SUV39H2) 106972687 106979835(SETDB1) 106983481(EHMT2) 106988167(PRDM2) 106989056(EHMT1)
BTA: 100138100(SETDB1) 509382(SETDB2) 514062(EHMT2) 523047(SUV39H1) 528606(EHMT1) 536936(SUV39H2) 789222(PRDM2)
BOM: 102264756(SUV39H2) 102271111(EHMT1) 102271191(SUV39H1) 102279999(EHMT2) 102281203(PRDM2) 102287560(SETDB2) 102288279(SETDB1)
BIU: 109555305(SETDB1) 109565691(EHMT1) 109566720(SETDB2) 109567973(SUV39H2) 109570372(PRDM2) 109576929(EHMT2)
BBUB: 102392662(SETDB2) 102395323(EHMT1) 102396138(PRDM2) 102401546(SUV39H1) 102405188(EHMT2) 102408652(SETDB1) 102415169(SUV39H2)
CHX: 102171636(PRDM2) 102174919(SUV39H1) 102176621(SUV39H2) 102178316(EHMT2) 102180982(SETDB1) 102186776(SETDB2) 102189411(EHMT1)
OAS: 101109230(SETDB1) 101110031(SUV39H1) 101115739(EHMT2) 101116064(SETDB2) 101116417(SUV39H2) 101123545(EHMT1) 105601941(PRDM2)
SSC: 100124382(EHMT2) 100157885(SETDB2) 100157920(SETDB1) 100518559(PRDM2) 110258080(EHMT1) 664651(SUV39H2) 767626(SUV39H1)
CFR: 102512057(SETDB1) 102512972(SUV39H1) 102514882(PRDM2) 102514903(SETDB2) 102518579(EHMT2) 102521199(SUV39H2) 102521526(EHMT1)
CDK: 105087443(EHMT2) 105101932 105102102(EHMT1) 105103196(SETDB1) 105103308(SUV39H1) 105104521(SUV39H2) 105107110(PRDM2)
BACU: 102999710(SUV39H2) 103005831(SUV39H1) 103009894(SETDB1) 103017152(SETDB2) 103017744(EHMT1) 103018553(EHMT2) 103020862(PRDM2)
LVE: 103068757(SETDB2) 103072310(EHMT2) 103073919(SUV39H1) 103076461(SETDB1) 103079038(EHMT1) 103083070(PRDM2) 103084616(SUV39H2) 103088198
OOR: 101269551(PRDM2) 101270688(SETDB1) 101272833(EHMT1) 101275448(SETDB2) 101279239(SUV39H2) 101282385(EHMT2) 101289196(SUV39H1)
DLE: 111169525(SUV39H1) 111169744(SETDB1) 111170699(EHMT2) 111175303 111176964(EHMT1) 111178089(SUV39H2) 111187234(PRDM2)
PCAD: 102974835(PRDM2) 102978732(EHMT1) 102981491 102988226(SUV39H2) 102988363(SUV39H1) 102990347(SETDB2) 102993056(EHMT2) 114486049 114486183
ECB: 100054973(PRDM2) 100056120(SETDB2) 100058869(EHMT1) 100059118(EHMT2) 100059254(SETDB1) 100062108(SUV39H1) 100068891(SUV39H2)
EPZ: 103544360 103544897(SUV39H1) 103547642(SETDB1) 103554163(EHMT1) 103556824(SUV39H2) 103563300(EHMT2) 103563428(SETDB2) 103564688(PRDM2)
EAI: 106822324(EHMT2) 106822761(EHMT1) 106827436(SUV39H1) 106828015(PRDM2) 106829693(SETDB2) 106840452(SUV39H2) 106846522(SETDB1)
MYB: 102243180(SUV39H1) 102245485(EHMT1) 102248401(SETDB2) 102249747(PRDM2) 102257713(SETDB1) 102260054(SUV39H2) 102263672(EHMT2)
MYD: 102756540(EHMT1) 102757145(SUV39H2) 102760935(PRDM2) 102763954(SUV39H1) 102765299(SETDB2) 102773684(SETDB1) 102773857(EHMT2)
MNA: 107531408(SETDB2) 107531564 107534821(SUV39H2) 107536199(EHMT1) 107538997(EHMT2) 107539129(SETDB1) 107541392(SUV39H1)
HAI: 109372277(SETDB1) 109373117(EHMT2) 109374812(SUV39H1) 109381271(PRDM2) 109382055(EHMT1) 109387125(SETDB2) 109393823(SUV39H2)
DRO: 112299124(PRDM2) 112302258(EHMT2) 112306260(EHMT1) 112313171 112313537(SETDB1) 112320455(SUV39H2) 112322458(SUV39H1)
PALE: 102879374(EHMT2) 102879589(PRDM2) 102886191(SETDB1) 102891996 102893102(EHMT1) 102894853(SUV39H1) 102898400(SUV39H2)
RAY: 107498490(EHMT2) 107499036(SETDB1) 107503067(EHMT1) 107504834(SUV39H2) 107505354 107510017(SETDB2) 107513143(PRDM2) 107515026(SUV39H1)
MJV: 108389857 108397103(SUV39H2) 108397963(PRDM2) 108400840(EHMT2) 108403560(SETDB2) 108404637 108405374(EHMT1) 108408400(SUV39H1) 108409453(SETDB1)
LAV: 100653780(SUV39H1) 100658021(PRDM2) 100659207(EHMT2) 100660736(EHMT1) 100670438 100673374(SETDB1) 100674328(SUV39H2) 104847199
MDO: 100010516(PRDM2) 100014806(SUV39H2) 100018670(SUV39H1) 100023838(EHMT1) 100025360(EHMT2) 100028710(SETDB2) 100618580(SETDB1)
SHR: 100922258(SUV39H1) 100928904(SETDB1) 100931147(EHMT2) 100932927(EHMT1) 100933751(SUV39H2) 100934863(SETDB2) 100934867(PRDM2)
PCW: 110198885(PRDM2) 110199440(EHMT2) 110201087(SUV39H1) 110205249(EHMT1) 110213411(SETDB2) 110217388(SUV39H2) 110220597(SETDB1)
OAA: 100078328(EHMT1) 100082943(EHMT2) 100083315(SETDB2) 100084051(SUV39H1) 100085175(SUV39H2) 100091318(SETDB1) 100681503(PRDM2)
GGA: 100859816(SETDB1) 112529925 112529927(SUV39H1) 395847(MLLT11) 417250(EHMT1) 418866(SETDB2) 419478(PRDM2) 426314(SUV39H2)
CJO: 107307203(SUV39H1) 107308162(SETDB2) 107308165(PHF11) 107319605(SUV39H2) 107321652(EHMT1) 107323354(PRDM2) 107324577(SETDB1)
NMEL: 110387900(SETDB1) 110391539(SUV39H1) 110392282(SUV39H2) 110402348 110406734(EHMT1) 110408674(PRDM2)
APLA: 101790074 101794756(SETDB1) 101795723(PRDM2) 101796000(SUV39H2) 101805087(EHMT1)
ACYG: 106035063(PHF11) 106035084(SETDB2) 106037080(EHMT1) 106040216(PRDM2) 106046190(SUV39H2) 106049268(SETDB1)
LSR: 110469585 110470972(SUV39H2) 110476787(PRDM2) 110476821(SETDB1) 110476956(EHMT1) 110481760(SUV39H1) 110482327
GFR: 102031848(SUV39H2) 102034546(SETDB1) 102036198(EHMT1) 102043625(SETDB2) 102043786(PHF11) 106631968(PRDM2)
FAB: 101806838(EHMT1) 101812782(PRDM2) 101812936(PHF11) 101814584 101816158(SUV39H2)
PHI: 102099526(EHMT1) 102101563(SETDB1) 102103897(PHF11) 102104074(SETDB2) 102106085 102110616(SUV39H1) 102111894(PRDM2) 102114300(SUV39H2) 106629066
PMAJ: 107204624(SUV39H2) 107211503 107212039(EHMT1) 107213672(PRDM2) 107214655(SETDB1)
CCAE: 111923103(SUV39H2) 111935294 111936927(EHMT1) 111938730(PRDM2) 111939473(SETDB1)
CCW: 104688230(EHMT1) 104689965 104693258(PRDM2) 104694491(SUV39H2)
ETL: 114060918 114065121(PRDM2) 114067139(EHMT1) 114067551(SUV39H2) 114071955(SETDB1) 114073290 114073634
FPG: 101912073(SETDB1) 101912234(PHF11) 101912815(SUV39H2) 101914490(PRDM2) 101916063(EHMT1) 101917763(SETDB2)
FCH: 102055212(SETDB1) 102055395 102057247(EHMT1) 102059458(SUV39H2) 106631029(PRDM2)
CLV: 102085960(EHMT1) 102088543 102092575(PRDM2) 102094505(SETDB1) 102098917(SUV39H2)
EGZ: 104124045(EHMT1) 104129700(SETDB1) 104131606(SETDB2) 104131607(PHF11) 104132393(SUV39H2) 104133098(PRDM2)
NNI: 104009017 104010895(PHF11) 104010896(SETDB2) 104014430(SETDB1) 104014630(SUV39H2) 104022219(EHMT1)
ACUN: 113486655(EHMT1) 113487883(PRDM2) 113488725(SETDB1) 113489224(SETDB2) 113489768(SUV39H2)
PADL: 103913457(PHF11) 103913458(SETDB2) 103915032(SUV39H2) 103918059(PRDM2) 103918930(EHMT1) 103919479(SETDB1)
AAM: 106482427(PRDM2) 106485143(SUV39H2) 106489242(PHF11) 106489246(SETDB2) 106493032(EHMT1) 106495416(SETDB1)
ASN: 102371718(PRDM2) 102374916(EHMT1) 102375358(SUV39H2) 102378805(SUV39H1) 102380189 102381770(EHMT2) 102382539(SETDB1)
AMJ: 102558468(SUV39H1) 102561958(PRDM2) 102563656(SUV39H2) 102564850(EHMT1) 102574756(EHMT2) 102575637(SETDB1) 102576351(SETDB2)
CMY: 102932556(PHF11) 102932781(SETDB2) 102933671(EHMT1) 102937045(SUV39H2) 102937828(SETDB1) 102937831(SUV39H1) 102942942(PRDM2)
CPIC: 101931963(SETDB1) 101939547(PRDM2) 101942163(EHMT1) 101945875(SUV39H2) 101947321(EHMT2) 101950077(PHF11) 101950365(SETDB2) 101951503(SUV39H1)
ACS: 100552443(setdb2) 100553897(suv39h1) 100556375(ehmt2) 100565730(ehmt1) 100565799(setdb1) 100567365(prdm2)
PVT: 110072610 110080651(SETDB2) 110080653(PHF11) 110081193(SUV39H1) 110081479(SETDB1) 110088696(EHMT2) 110089799(EHMT1)
PBI: 103049261(EHMT2) 103052540(SUV39H1) 103053131(SETDB1) 103053645 103057390(EHMT1) 103060604(PRDM2) 103067345 107326457(PHF11)
PMUR: 107283956 107284269(SETDB2) 107291380(PRDM2) 107292899(SETDB1) 107295037(EHMT2) 107297347(EHMT1) 107300048(SUV39H1) 107302473
PMUA: 114583936 114586177(SETDB1) 114588136(SUV39H1) 114589035(EHMT1) 114592073(EHMT2) 114593254(SETDB2) 114602405(PRDM2)
GJA: 107105480(EHMT2) 107106223(PRDM2) 107112843(SUV39H1) 107113385(SETDB2) 107118801(EHMT1) 107119301 107119302 107121584(SETDB1)
XLA: 100037174(suv39h2.L) 108696585(prdm2.L) 108698163(ehmt1.L) 108698559(ehmt2.L) 108699889(ehmt1.S) 108700299(suv39h1.S) 108700333(setdb1.S) 108713053(suv39h2.S) 398711(setdb2.S) 431943(suv39h1.L) 432147(setdb1.L) 494709(prdm2.S)
XTR: 100124713(ehmt1) 100124743(setdb2) 100170624(prdm2) 100484992(ehmt2) 100490309(setdb1) 549262(suv39h2)
NPR: 108783946(PRDM2) 108786543(EHMT2) 108788266(SUV39H1) 108789810(SETDB1) 108794066(SUV39H2) 108794390(EHMT1) 108797823(SETDB2)
DRE: 100003615(prdm2a) 100005761(ehmt1a) 326906(suv39h1b) 335153(setdb2) 402830(ehmt1b) 445198(suv39h1a) 553292(setdb1a) 569250(ehmt2) 768131(setdb1b) 797296(prdm2b)
CSEM: 103384853(suv39h1) 103384937 103385671(prdm2) 103388279(setdb1) 103389041 103389803(setdb2) 103394057(ehmt2) 103394578 103397363
SFM: 108918498(prdm2) 108922673(ehmt1) 108923796(setdb1) 108924930 108934780(suv39h1) 108935584(ehmt2) 108937739 108938542
LCM: 102351913 102356699(SETDB1) 102359250(PRDM2) 102359445(EHMT2) 102360554(SUV39H2) 102361297(EHMT1) 102363588(SETDB2) 106705364
CMK: 103173106 103180404(ehmt1) 103181338(prdm2)
RTP: 109911717(setdb2) 109919887(ehmt2) 109921345(suv39h2) 109925832 109926709(ehmt1) 109937263(prdm2)
DME: Dmel_CG12196(egg) Dmel_CG2995(G9a) Dmel_CG43664(Su(var)3-9) Dmel_CG43665(eIF2gamma)
DSI: Dsimw501_GD16494(Dsim_GD16494) Dsimw501_GD24920(Dsim_GD24920)
NVI: 100116736(SUV39H1) 100120014(Setdb1) 100121084(Ehmt1)
BMOR: 101742950 101743644 692623(Su(var)3-9)
CEL: CELE_R05D3.11(met-2)
CBR: CBG18157(Cbr-met-2)
TSP: Tsp_05330
EGL: EGR_06122
ATH: AT1G17770(SUVH7) AT1G73100(SUVH3) AT2G22740(SUVH6) AT2G24740(SDG21) AT2G33290(SUVH2) AT2G35160(SUVH5) AT4G13460(SUVH9) AT5G04940(SUVH1) AT5G13960(SUVH4)
LJA: Lj0g3v0007239.1(Lj0g3v0007239.1) Lj0g3v0128679.1(Lj0g3v0128679.1) Lj0g3v0265609.1(Lj0g3v0265609.1) Lj0g3v0266169.1(Lj0g3v0266169.1) Lj0g3v0269559.1(Lj0g3v0269559.1) Lj0g3v0293009.1(Lj0g3v0293009.1) Lj1g3v3904410.1(Lj1g3v3904410.1) Lj1g3v4059050.1(Lj1g3v4059050.1) Lj2g3v1989010.1(Lj2g3v1989010.1) Lj2g3v1989010.2(Lj2g3v1989010.2) Lj2g3v1989010.3(Lj2g3v1989010.3) Lj2g3v1989020.1(Lj2g3v1989020.1) Lj2g3v1989030.1(Lj2g3v1989030.1) Lj2g3v1989040.1(Lj2g3v1989040.1) Lj2g3v1989040.2(Lj2g3v1989040.2) Lj5g3v2244670.1(Lj5g3v2244670.1) Lj6g3v0156100.1(Lj6g3v0156100.1) Lj6g3v0156120.1(Lj6g3v0156120.1)
DOSA: Os01t0811300-01(Os01g0811300) Os01t0927000-01(Os01g0927000) Os03t0320400-01(Os03g0320400) Os04t0544100-01(Os04g0544100) Os05t0490700-01(Os05g0490700) Os07t0435900-01(Os07g0435900) Os08t0399300-00(Os08g0399300) Os08t0400000-01(Os08g0400000) Os08t0400200-00(Os08g0400200) Os08t0565700-01(Os08g0565700) Os09t0362900-01(Os09g0362900) Os11t0131600-00(Os11g0131600) Os11t0602200-01(Os11g0602200) Os12t0128450-00(Os12g0128450)
ATS: 109741537(LOC109741537) 109741621 109744867(LOC109744867) 109746199(LOC109746199) 109749138(LOC109749138) 109749619(LOC109749619) 109750455(LOC109750455) 109751482(LOC109751482) 109761403(LOC109761403) 109766085(LOC109766085) 109769949(LOC109769949) 109769961(LOC109769961) 109770115 109771886 109774279(LOC109774279) 109777308(LOC109777308) 109782755(LOC109782755)
CRE: CHLREDRAFT_6823(SET3)
VCN: VOLCADRAFT_93418(VSET3)
NCR: NCU04402(dim-5)
NTE: NEUTE1DRAFT121214(NEUTE1DRAFT_121214)
MGR: MGG_06852
SSCK: SPSK_07647
NHE: NECHADRAFT_94199(SDG2104)
MAW: MAC_09094
MAJ: MAA_00272
CMT: CCM_00746
BFU: BCIN_11g02360(BcDIM5)
MBE: MBM_05751
ANI: AN1170.2
ANG: ANI_1_1828074(An08g03380)
ABE: ARB_02816
TVE: TRV_01916
PTE: PTT_11395
ZTR: MYCGRDRAFT_107709(SDG2411)
SPO: SPBC428.08c(clr4)
CNE: CNH00720
CNB: CNBL0680
LBC: LACBIDRAFT_296206(SDG16210)
ABP: AGABI1DRAFT108076(AGABI1DRAFT_108076) AGABI1DRAFT129982(AGABI1DRAFT_129982)
ABV: AGABI2DRAFT146074(AGABI2DRAFT_146074) AGABI2DRAFT180791(AGABI2DRAFT_180791)
DFA: DFA_00949(suvA)
 » show all
Taxonomy
Reference
1  [PMID:11094092]
  Authors
O'Carroll D, Scherthan H, Peters AH, Opravil S, Haynes AR, Laible G, Rea S, Schmid M, Lebersorger A, Jerratsch M, Sattler L, Mattei MG, Denny P, Brown SD, Schweizer D, Jenuwein T
  Title
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase  gene that displays testis-specific expression.
  Journal
Mol Cell Biol 20:9423-33 (2000)
  Sequence
[mmu:20937 64707]
Reference
2  [PMID:11867540]
  Authors
Schotta G, Ebert A, Krauss V, Fischer A, Hoffmann J, Rea S, Jenuwein T, Dorn R, Reuter G
  Title
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.
  Journal
EMBO J 21:1121-31 (2002)
  Sequence
Reference
3  [PMID:12130538]
  Authors
Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y
  Title
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.
  Journal
Genes Dev 16:1779-91 (2002)
  Sequence
[mmu:110147]
Reference
4  [PMID:11959841]
  Authors
Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ 3rd
  Title
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase  that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.
  Journal
Genes Dev 16:919-32 (2002)
  Sequence
[hsa:9869]
Reference
5  [PMID:14633678]
  Authors
Kim KC, Geng L, Huang S
  Title
Inactivation of a histone methyltransferase by mutations in human cancers.
  Journal
Cancer Res 63:7619-23 (2003)
  Sequence
[hsa:7799]
Reference
6  [PMID:20084102]
  Authors
Wu H, Min J, Lunin VV, Antoshenko T, Dombrovski L, Zeng H, Allali-Hassani A, Campagna-Slater V, Vedadi M, Arrowsmith CH, Plotnikov AN, Schapira M
  Title
Structural biology of human H3K9 methyltransferases.
  Journal
PLoS One 5:e8570 (2010)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.355
IUBMB Enzyme Nomenclature: 2.1.1.355
ExPASy - ENZYME nomenclature database: 2.1.1.355
BRENDA, the Enzyme Database: 2.1.1.355

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