KEGG   ENZYME: 2.1.1.44
Entry
EC 2.1.1.44                 Enzyme                                 
Name
L-histidine Nalpha-methyltransferase;
dimethylhistidine N-methyltransferase;
dimethylhistidine methyltransferase;
histidine-alpha-N-methyltransferase;
S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase;
S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine Nalpha-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase (hercynine-forming)
Reaction(IUBMB)
3 S-adenosyl-L-methionine + L-histidine = 3 S-adenosyl-L-homocysteine + hercynine (overall reaction) [RN:R01169];
(1a) S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + Nalpha-methyl-L-histidine [RN:R10523];
(1b) S-adenosyl-L-methionine + Nalpha-methyl-L-histidine = S-adenosyl-L-homocysteine + Nalpha,Nalpha-dimethyl-L-histidine [RN:R10524];
(1c) S-adenosyl-L-methionine + Nalpha,Nalpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + hercynine [RN:R04436]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
L-histidine [CPD:C00135];
Nalpha-methyl-L-histidine;
Nalpha,Nalpha-dimethyl-L-histidine [CPD:C04259]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
hercynine [CPD:C05575];
Nalpha-methyl-L-histidine;
Nalpha,Nalpha-dimethyl-L-histidine [CPD:C04259]
Comment
Part of the biosynthetic pathway of ergothioneine.
History
EC 2.1.1.44 created 1976, modified 2013
Pathway
ec00340  Histidine metabolism
ec01100  Metabolic pathways
Orthology
K18911  L-histidine Nalpha-methyltransferase
K20246  L-histidine Nalpha-methyltransferase / hercynylcysteine S-oxide synthase
Genes
QSU111995461
NCRNCU04343(egt-1)
NTENEUTE1DRAFT145472(NEUTE1DRAFT_145472)
SMPSMAC_01803
MTMMYCTH_2074210
CTHRCTHT_0030600
MGRMGG_00020 MGG_13219
PPEIPpBr36_02899
TMNUCRPA7_3011
SSCKSPSK_08945
FGRFGSG_03421 FGSG_11987 FGSG_12773
FPUFPSE_06241 FPSE_08378 FPSE_11477
FVRFVEG_15947
FOXFOXG_20012
NHENECHADRAFT_70968 NECHADRAFT_97208
TRETRIREDRAFT_81410
TRRM419DRAFT_103267
MAWMAC_09617
MAJMAA_04856
CMTCCM_07351
PLJVFPFJ_01447
VDAVDAG_10242
CFJCFIO01_13296
CLUPCLUP02_15291
CHIGCH63R_04852
SAPOSAPIO_CDS7015
PFYPFICI_05616
BFUBCIN_12g04180
MBEMBM_01989
PSCOLY89DRAFT_586353
GLZGLAREA_08265
ANIAN7620.2
AFMAFUA_2G15650
ACTACLA_074540
NFINFIA_090880
AORAO090012000265 AO090023000415
ANGANI_1_792134(An15g05880)
AFVAFLA_001980 AFLA_006763
ALUCAKAW2_60182A
ACHEACHE_10907A ACHE_60451S
APUUAPUU_80300A
PDPPDIP_81160
TMFPMAA_036630
TRGTRUGW13939_05155
CIMCIMG_00276
CPWCPC735_059060
UREUREG_00352
PBLPAAG_03909
PBNPADG_11594
ABEARB_02453
TVETRV_08045
AJEHCAG_01026
BGHBDBG_06484
PNOSNOG_13930(SNOG_13929)
PTEPTT_06791
BZECOCCADRAFT_109454
BSCCOCSADRAFT_32544
BORCOCMIDRAFT_95519
AALTCC77DRAFT_949140
ZTRMYCGRDRAFT_75935
PFJMYCFIDRAFT_56905
FFUCLAFUR5_11164
BCOMBAUCODRAFT_116776
NPAUCRNP2_8392
SPOSPBC1604.01(mug158)
CNECNJ01670
CNBCNBJ1790
CNGCNAG_04737
CGICGB_I2320W
TMSTREMEDRAFT_42626
TASAA1Q1_06211
TVSTRAVEDRAFT_64341
DSQDICSQDRAFT_55495
PCOPHACADRAFT_212229
SHSSTEHIDRAFT_66030
HIRHETIRDRAFT_156207
PSQPUNSTDRAFT_131244
ADLAURDEDRAFT_115403
FMEFOMMEDRAFT_78835
GTRGLOTRDRAFT_139012
LBCLACBIDRAFT_188236
CCICC1G_02949
ABPAGABI1DRAFT120644(AGABI1DRAFT_120644)
ABVAGABI2DRAFT186400(AGABI2DRAFT_186400)
PCUBJR316_0007212
MRRMoror_1006
MOREE1B28_012164
SCMSCHCO_02619710(SCHCODRAFT_02619710)
CPUTCONPUDRAFT_77468 CONPUDRAFT_85801
SLASERLADRAFT_470869
WSEWALSEDRAFT_60925
WICJ056_001286
PGRPGTG_04084
MLRMELLADRAFT_110519
XCTJ151_00302
XCJJ158_00300
XCUJ159_00300
XCNJ169_00298
XCWJ162_00299
XCRJ163_00299
XCMJ164_00299
XCFJ172_00293
XOYAZ54_01380
XOZBE73_23120
XFRBER92_18705
XVEBJD12_13500
XPEBJD13_16140
XHRXJ27_16615
XGABI317_23860
XPHXppCFBP6546_11000(egtD)
XVAC7V42_00720(egtD) C7V42_00735(egtD)
XANAC801_00745
XARXB05_17615
LUMCNR27_02125(egtD)
LUSE5843_00855(egtD)
LUGFPZ22_03180(egtD)
PFWPF1751_v1c25760
PFFPFLUOLIPICF724150
SWDSwoo_2444
PLZS4054249_09460
TTUTERTU_3974
LLG44548918_01364(egtD)
LSSNCTC12082_00682(egtD)
MMOBF6R98_12630
MEJQ7A_3010(egtD)
PSALPSLF89_1164
THISHZT40_03135 HZT40_04295
TGRTgr7_2473
TKMTK90_0941
TVRTVD_07835
APRSBI364_03780
ABOABO_0654
ALNAS19_06710
ADIB5T_03346
AXEP40_15710
ACIIC4901_08395(egtD)
ATYA9R16_009445(egtD)
SALNSALB1_3448
RSLRPSI07_2433
RSEF504_929
RPFRpic12D_0892
RPJN234_15270
RPUCDC45_04875(egtD)
REHH16_A2701(h16_A2701)
CNCCNE_1c25990
CUHBJN34_14555
REUReut_A0917
RMERmet_2566
CTIRALTA_A2191
CBWRR42_m2994
CGDCR3_1928
CCUPBKK81_15190
CUPBKK80_16140
CUUBKK79_16810
CPAUEHF44_10300(egtD)
COXE0W60_22780(egtD)
CCAMM5D45_11930(egtD)
CCAXKZ686_14395(egtD)
BTHADR62_4162
BTHLBG87_4458(egtD)
BVEAK36_732(egtD)
BCEOI35_3269
BMULNP80_157(egtD)
BCEPAPZ15_04060
BPYRABD05_06170
BCONNL30_19380
BDFWI26_00140
BLATWK25_02555
BTEIWS51_10965
BSEMWJ12_00170
BPSLWS57_13120
BMECWJ16_00135
BSTGWT74_00250
BSTLBBJ41_09710
BGUKS03_4158(egtD)
BGOBM43_5978(egtD)
BUEBRPE67_BCDS00910
BUQAC233_26305
BGPBGL_2c23700
BPLAbpln_2g24000
BUDAQ610_27135
BUZAYM40_35415
BFNOI25_5492(egtD)
BCAIK788_0000696
PSPWBJG93_21620(egtD)
PARABTO02_22315
PARBCJU94_28475(egtD)
PHSC2L64_18440(egtD)
PTERC2L65_16275(egtD)
PGPCUJ91_29930(egtD)
PCJCUJ87_28135(egtD)
PTSCUJ90_23585(egtD)
PMEGFNZ07_04790(egtD)
PTROG5S35_20685(egtD)
PGISI6I06_27965(egtD)
PACPFAZ97_23670(egtD)
PACSFAZ98_19070(egtD)
AJSAjs_2288
ACRABSY15_3490(egtD)
DACDaci_4835
DELDelCs14_2019
DTSBI380_31530
DHKBO996_22075
ADNAlide_2608
ADKAlide2_2925
LIHL63ED372_02888(egtD)
HYRBSY239_2998(egtD)
HYBQ5W_16970
HTNKI616_07160(egtD)
HCZG9Q37_12970(egtD)
DPYBA022_06180
DIHG7047_22070(egtD)
DIADtpsy_1586
MELAC6568_01560(egtD)
MJELVC68_10285(egtD)
UNDUNDKW_5371
LCHLcho_1724
NIZNNRS527_02106
SPLBSFPGR_16830
TAKTharo_2010
ATWC0099_07925
GEMGM21_2631
GEOGeob_1692
GBMGbem_1582
GBNGEOBRER4_25530
MXAMXAN_7473
MSDMYSTI_08113
MYMA176_007054
MFBMFUL124B02_43145
CCXCOCOR_08068
MFULILAB_08960
MMASMYMAC_007189
SURSTAUR_8338
AGEAA314_00409
AVMJQX13_14735(egtD)
MBDMEBOL_003284
CFUSCYFUS_009890
VINAKJ08_3635
CCROCMC5_025140
MRMA7982_07704
BSEDDN745_18535(egtD)
RBTNOVO_04395 NOVO_05715
MESMEJ066_13070
BJPRN69_41265
STARG3545_14755(egtD)
MPHYMCBMB27_00380
METXA3862_26640
MMESMMSR116_19855(egtD)
CMBCSW64_04980(egtD)
NREBES08_23380
NOVTQ38_002330(egtD)
NOGGKE62_07105(egtD)
SPHKSKP52_19325
SPHPLH20_18580
SMAGAN936_19175
SMAZLH19_23055
STERAOA14_09935
SGISGRAN_4049(egtD)
SPHQBWQ93_14620
SPHOC3E99_16660(egtD)
SPHXE5675_00900(egtD)
SPHUSPPYR_1207(egtD) SPPYR_3476
SPHDHY78_22775
SPHITS85_16705
SSANNX02_16490
SNJA7E77_06940
SMYBJP26_02510
SPANAWL63_03915
SPLMBXU08_15120
SPLKAV944_01330
SPHCCVN68_15810(egtD)
SPHFDM480_05990(egtD)
SPAUDRN02_014595(egtD)
SRHIH9L12_11100(egtD)
SPAPH3Z74_19915(egtD)
SXAFMM02_05405(egtD)
SPAIFPZ24_01285(egtD)
SARIH5J25_18495(egtD)
SAERNEF64_00085(egtD)
SINBSIDU_15825
SYBTZ53_01600
SBDATN00_09735
SPMIK663_03035
SPHBEP837_01893(egtD)
SPHTK426_19995
SYAA6768_25175(egtD)
SPYGYGS_C1P2050
SUFLFIL70_13120(egtD)
SAMISAMIE_1000900
CIJWG74_14665
SPHGAZE99_02630
SFLASPHFLASMR4Y_01850(egtD)
SPHYCHN51_02940(egtD)
BLASBSY18_3729(egtD)
BFWB5J99_08985
SPHJBSL82_14530
SPZRG5C33_18965(egtD)
PALGHFP57_11255(egtD)
PARJJ4G78_14170(egtD)
AEPAMC99_01598
ALBAEB_P1475
ALHG6N82_13730(egtD)
AAYWYH_01210(egtD)
AMXAM2010_463
ANHA6F65_01268(egtD)
ADOA6F68_01856(egtD)
CNAAB433_11925
CMANA9D14_10260
ERYCP97_06905
EGNBMF35_a1447
EFVCHH26_05895(egtD)
ELQGa0102493_112097
ERKCD351_12280(egtD)
ERRDVR09_12255(egtD)
ERFFIU90_12290(egtD)
EMVHQR01_02070(egtD)
PNSA9D12_00190
PORLBG023_112356
POTE2E27_09150(egtD)
ACIMGT370_10905(egtD)
HAXBALOs_0888
MTURv3701c(egtD)
MTVRVBD_3701c
MTCMT3804
MRAMRA_3737
MTFTBFG_13732
MTBTBMG_03744
MTKTBSG_03768
MTZTBXG_003715
MTGMRGA327_22795
MTIMRGA423_23340
MTECCDC5079_3432
MTURCFBS_3922
MTLCCDC5180_3383
MTOMTCTRI2_3771
MTDUDA_3701c
MTNERDMAN_4054
MTJJ112_19890
MTUBMT7199_3766
MTUEJ114_19770
MTXM943_19015
MTULTBHG_03636
MTUTHKBT1_3906
MTUUHKBT2_3916
MTQHKBS1_3919
MBOBQ2027_MB3727C
MBBBCG_3760c
MBTJTY_3762
MBMBCGMEX_3761c
MBKK60_038400
MBXBCGT_3563
MAFMAF_37090
MMICRN08_4081
MCEMCAN_37221
MCQBN44_120099
MCVBN43_90208
MCXBN42_90217
MCZBN45_110057
MPAMAP_0303c
MAOMAP4_3568
MAVIRC58_17730
MAVURE97_17760
MAVMAV_0402
MITOCO_03550
MIAOCU_03620
MIDMIP_00739
MYOOEM_03670
MCHIAN480_01810
MIROCQ_03570
MMALCKJ54_01715(egtD)
MMANMMAN_46310(egtD)
MSAMycsm_06027
MULMUL_4285
MMIMMAR_5212
MMAEMMARE11_50350
MLIMULP_05489
MPSEMPSD_02570(egtD)
MSHOMSHO_10450(egtD)
MMCMmcs_4879
MKMMkms_4968
MJLMjls_5247
MMMW7S_01745
MKNMKAN_13320
MYVG155_27720
MYEAB431_27325
MGOAFA91_03445
MHADB586_03755
MDXBTO20_03110
MSHGMSG_04705(egtD)
MFJMFLOJ_39080(egtD)
MSTOMSTO_42940(egtD)
MSIMMSIM_27490(egtD)
MSAKMSAS_31070(egtD)
MKUI2456_26520(egtD)
MGROFZ046_03785(egtD)
MXEMYXE_03650(egtD)
MNVMNVI_14030(egtD)
MPAGC0J29_28780(egtD)
MNMMNVM_22180(egtD)
MGORH0P51_26675(egtD)
MCOOMCOO_28640(egtD)
MBAIMB901379_04622(egtD)
MSEOMSEO_36210(egtD)
MHEKJMUB5695_00322(egtD)
MGAUMGALJ_40180(egtD)
MLJMLAC_45740(egtD)
MBRDMBRA_18310(egtD)
MSHJMSHI_37090(egtD)
MKRMKOR_31800(egtD)
MDFK0O62_26740(egtD)
MMAMK3U93_23410(egtD)
MHOLK3U96_02225(egtD)
MHERK3U94_21785(egtD)
MSENK3U95_26770(egtD)
MPAEK0O64_26850(egtD)
MSPGF6B93_21305(egtD)
MOTLTS72_26800(egtD)
MVMMJO54_21640(egtD)
MRFMJO55_25020(egtD)
MPAAMKK62_01140(egtD)
MCROMI149_27185(egtD)
MSMMSMEG_6247
MSGMSMEI_6086
MSBLJ00_30890
MSNLI99_30895
MSHLI98_30900
MVAMvan_5483
MGIMflv_1318
MSPMspyr1_48610
MCBMycch_4828
MNED174_25555
MYNMyAD_25095
MFTXA26_56020
MPHLMPHLCCUG_00354(egtD)
MVQMYVA_5373
MLLB1R94_26505
MRHMycrhN_2101
MTHN4412656_04306(egtD)
MHASMHAS_03906(egtD)
MDUMDUV_47520(egtD)
MCHTMCHIJ_17980(egtD)
MDRMDOR_34080(egtD)
MAUUNCTC10437_05228(egtD)
MMAGMMAD_50010(egtD)
MMORMMOR_09310(egtD)
MFXMFAL_07420(egtD)
MAICMAIC_03600(egtD)
MIJMINS_21350(egtD)
MALVMALV_39950(egtD)
MTYMTOK_19920(egtD)
MPSCMPSYJ_14330(egtD)
MARZMARA_45920(egtD)
MGADMGAD_39070(egtD)
MHEVMHEL_26110(egtD)
MSARMSAR_12290(egtD)
MANYMANY_34890(egtD)
MAUBMAUB_28590(egtD)
MPOFMPOR_01120(egtD)
MPHUMPHO_41590(egtD)
MMUCC1S78_026760(egtD)
MMATMMAGJ_31210(egtD)
MBOKMBOE_07330(egtD)
MFGK6L26_04015(egtD)
MSEIMSEDJ_04750(egtD)
MFLVNCTC10271_00327(egtD)
MCEEMCEL_35690(egtD)
MMONEWR22_26360(egtD)
MABMAB_0372
MMVMYCMA_0196
MABBMASS_0368
MABLMMASJCM_0364
MCHEBB28_01815
MIZBAB75_02380
MSTEMSTE_00331(egtD)
MSAOMYCSP_01630
MSALDSM43276_00322(egtD)
MJDJDM601_3981
MTER4434518_03928(egtD)
MMINMMIN_14010(egtD)
MHIBMHIB_32410(egtD)
ASDAS9A_2107
MPAKMIU77_00525(egtD)
CORYFQV43_01340
NFANFA_48840
NFRERS450000_05025(egtD)
NCYNOCYR_4670
NBRO3I_036990
NNONONO_c66340(egtD)
NSLBOX37_13640 BOX37_27025
NSRNS506_01661(egtD)
NTPCRH09_33200(egtD) CRH09_34695(egtD)
NOZDMB37_15930(egtD)
NODFOH10_01820(egtD)
NAHF5544_39490(egtD)
NADNCTC11293_06258(egtD)
NWLNWFMUON74_10250(egtD)
NIEKV110_36240(egtD)
NTCKHQ06_11080(egtD)
NHUH0264_10245(egtD)
NYALTV02_22535(egtD)
NGPLTT66_17710(egtD)
RHARHA1_ro05703
RERRER_43170
REYO5Y_20230
REBXU06_20400
RQIC1M55_21745(egtD)
ROPROP_57720
ROAPd630_LPD02318
RPYY013_21565
RBYCEJ39_08085(egtD)
RHBNY08_2330
RAVAAT18_07305
RFAA3L23_00519(egtD)
RHSA3Q41_02834(egtD)
RHWBFN03_01865
RRZCS378_22375(egtD)
RHUA3Q40_02531(egtD)
RHQIM25_11355
RHODAOT96_01790
RRT4535765_01117(egtD)
RCRNCTC10994_01623(egtD)
RTMG4H71_04775(egtD)
RKOJWS14_31235(egtD)
RGOKYT97_28820(egtD)
ROZCBI38_22555
RPSKJWS13_13060(egtD)
RGORNMQ04_04980(egtD)
REQREQ_12490
GTABCM27_03245
GRUGCWB2_02880(egtD)
GOMD7316_02909(egtD)
GAVC5O27_02155(egtD)
GODGKZ92_02680(egtD)
GJIH1R19_02530(egtD)
GOILK459_06365(egtD)
GHNMVF96_03025(egtD)
GAMIIHQ52_01895(egtD)
GMGNWF22_13205(egtD)
SPINKV203_14460(egtD)
TPULTPB0596_00170(egtD)
SRTSrot_1375
DITC3V38_03550
DIZCT688_14125(egtD)
DPCA6048_14775
DLUA6035_14115
DKNNHB83_14345(egtD)
TOYFO059_06635(egtD)
SCOSCO0913(SCM1.46)
SALBXNR_5669
SMASAVERM_7338(egtD)
SGRSGR_698
SGBWQO_31700
SCBSCAB_11241
SSXSACTE_6222
SVLStrvi_4089
SHYSHJG_7892
SHOSHJGH_7654
SRCM271_04975
SMALSMALA_7430
SSOII1A49_40910(egtD)
SFASfla_0407
SBHSBI_01721 SBI_04408
SVESVEN_6867
SDVBN159_1332
SALSSLNWT_7175
STRPF750_6592
SFISFUL_6743
SCIB446_32005
SLVSLIV_33365(egtD)
SGUSGLAU_29355(egtD)
SVTSVTN_34045
STREGZL_01890
SCWTU94_30465
SLDT261_1097
SLCSL103_16955 SL103_23145
SXISXIM_40600
STRMM444_29575
SAMBSAM23877_6627(egtD)
SPRISPRI_0731
SCZABE83_02240
SCXAS200_07595
SRWTUE45_00191(egtD)
STRFASR50_31985
SLEsle_06860(sle_06860)
SRNA4G23_05242(egtD)
SPAVSpa2297_29065
STRTA8713_28665
SCLFBB341_01715
SGSAVL59_16350
STSIA4E84_35860
SKYD0C37_30425(egtD)
SALWCP975_32100(egtD)
SGMGCM10017557_08730(egtD)
SCADDN051_06580(egtD)
SPHWNFX46_13770(egtD)
SLSSLINC_7405
SNRSNOUR_08415(egtD)
SALUDC74_173 DC74_6876
SALLSAZ_01310 SAZ_35720
SPLULK06_001550
STRDNI25_03155
SNWBBN63_03445
SAUOBV401_40770
SSIAA7J05_03980
SVUB1H20_32545
SPUNBFF78_04725
SGVB1H19_34870
SLAUSLA_6648
SALFSMD44_07734
SALJSMD11_0418 SMD11_0807 SMD11_5689
SLXSLAV_06120(egtD)
STROSTRMOE7_32360
SFKKY5_7465c
SNZDC008_30815(egtD)
SGEDWG14_01147(egtD)
SRJSRO_0888
SLKSLUN_35075(egtD)
SDXC4B68_03760(egtD)
SGDELQ87_04140(egtD)
SQZFQU76_31345(egtD)
SCYAEJ357_04515(egtD)
SASTCD934_31540(egtD)
SNQCP978_05165(egtD)
STIRDDW44_28475(egtD)
SKACP970_02865(egtD)
SGZC0216_12610(egtD)
SVNCP980_05110(egtD)
SNKCP967_00615(egtD)
SHAWCEB94_36715(egtD)
SRKFGW37_04875 FGW37_27930(egtD) FGW37_32380
SFICEIZ62_03285(egtD)
SGALCP966_32080(egtD)
SSPODDQ41_29455(egtD)
SVRCP971_05385(egtD)
SPADDVK44_31770(egtD)
SFYGFH48_07305(egtD)
SAQUEJC51_40705(egtD)
SGFHEP81_00867(egtD)
SCAVCVT27_31290(egtD)
SSEOD0Z67_26295(egtD)
SBYH7H31_32630(egtD)
SRIMCP984_04955(egtD)
SSUBCP968_05400(egtD)
SPHVF9278_42705(egtD)
SCINCP977_30670(egtD)
SFUGCNQ36_03160(egtD)
SPACB1H29_03980
STSUB7R87_31255
SCHACP983_04580(egtD)
SGXH4W23_35695(egtD)
SCOECP976_38155(egtD)
SBATG4Z16_03275(egtD)
SSPBCP982_35760(egtD)
SNFJYK04_07182(egtD)
SPLACP981_32920(egtD)
SBROGQF42_38855(egtD)
STUIGCM10017668_06280(egtD)
SATAC5746_37015(egtD)
SCHFIPT68_32685(egtD)
SHUNDWB77_01279(egtD)
SHARHUT13_20305
SCYGS1361_34720(egtD)
SFEUIM697_19420(egtD)
SLIAHA039_02865(egtD)
SDWK7C20_31590(egtD)
SCALI6J39_32345(egtD)
SAUHSU9_029815(egtD)
SFBCP974_27935(egtD)
SMOBJ7W19_29430(egtD)
SPRACP972_32040(egtD)
SPEUCGZ69_32680(egtD)
SROIIAG44_35305(egtD)
SXNIAG42_04110(egtD)
SGJIAG43_01385(egtD)
SHKJ2N69_33970(egtD)
SANUK7396_05830(egtD)
STRYEQG64_32490(egtD)
SDDD9753_03475(egtD)
SACTDMT42_33780(egtD)
SMAOCAG99_16355
SGOBtest1122_11450(egtD)
SINEKI385_37410(egtD)
SLFJEQ17_07335(egtD)
SDECL3078_39935(egtD)
SAOVG3H79_03210(egtD)
SDURM4V62_05430(egtD)
SYANNRK68_30035(egtD)
SRUGF0345_02150(egtD)
SAKBK1J60_03885(egtD) K1J60_05755(egtD)
STAALDH80_06200(egtD)
SCTSCAT_4662
SCYSCATT_46540
KSKKSE_64540
KABB7C62_33770
KAUB6264_00790
KITCFP65_6446
KISHUT16_30585(egtD)
STRIC7M71_003900(egtD)
YIALO772_26255(egtD)
STRHGXP74_23635(egtD)
ABRYNYE86_31875(egtD)
ARTPE5206_18075(egtD)
LMOIVV02_12415
JTEASJ30_00890
JLIEXU32_14490(egtD)
JAYH7A72_00935(egtD)
PHWG7075_16285(egtD)
MICGGJV80_10935(egtD)
NCANoca_1639
NDKI601_1452(egtD)
NBEBack2_08840(egtD)
NAROCFH99_00195(egtD)
NAQUENKNEFLB_01971(egtD)
NCQK6T13_00790(egtD)
NPCKUV85_08465(egtD)
NPSKRR39_12860(egtD)
PSIMKR76_00175
AEBC6I20_01175(egtD)
KFLKfla_5160
KQIF1D05_08725(egtD)
NDANdas_0640 Ndas_3470
NALB005_3535
NGVCDO52_21005(egtD)
NEXNE857_10265(egtD)
STRREKD16_07235(egtD)
SNAHOUQ99_23975(egtD)
TCUTcur_3638
ACTWF7P10_32765(egtD)
AGRAAGRA3207_006138(egtD)
SROSros_0329
NOABKM31_30895
NOWGBF35_07835(egtD)
NCXNocox_11935(egtD)
NGNLCN96_14315(egtD)
TBITbis_2648
FRAFrancci3_4514
FREFranean1_7303
FRIFraEuI1c_6654 FraEuI1c_7155
FALFRAAL6843
FSYFsymDg_4504
NMLNamu_1079
GOBGobs_0202
SENSACE_3823
SACGFDZ84_35805(egtD)
SVISvir_22440
SACCEYD13_12490(egtD)
AMDAMED_4961
AMNRAM_25255
AMMAMES_4902
AMZB737_4902
AOIAORI_3755
AJAAJAP_20380(egtD)
AMQAMETH_3014
AMYCCU254_17960(egtD)
AMYBBKN51_11250
AABA4R43_11135
AMYYYIM_27645(egtD)
AORISD37_19260
AACDLWP59_15000(egtD)
APRTMUY14_12805(egtD)
AROONQK81_03805(egtD)
ATHML1857_17965(egtD)
PDXPsed_2366 Psed_3380
PSEAWY02_03165 WY02_08125
PSEEFRP1_09630
PSEHXF36_09105
PSEQAD006_17190
PECQAD017_25025
PHHAFB00_25190
PAUTPdca_32250 Pdca_32260
PBROHOP40_24490(egtD)
PPELH6H00_23195(egtD)
APRECNX65_10835(egtD)
AMIAmir_2125
SESPBN6_30880
SSYIEKG83_34685(egtD)
KALKALB_2953
KPHYAOZ06_20030
LEDBBK82_27285
AHMTL08_10815
ACTIUA75_11540
ACADUA74_11455
AHGAHOG_10790(egtD)
ACTAC1701_22040(egtD)
ALOCRK56189 CRK60771
PMADBAY61_17175
SACEGIY23_01060 GIY23_10335(egtD)
ACTUActkin_04014(egtD)
STPStrop_2116
SAQSare_2259
MAUMicau_3408
MILML5_4986
MICBMicB006_2465
MTUACSH63_08020(egtD)
MICHFJK98_16750(egtD)
MTEMGCE86_12995(egtD)
MCABHXZ27_18525(egtD)
MSAGGCM10017556_54360(egtD)
VMAVAB18032_23555
MCRAID554_01375(egtD)
VERHUT12_20330(egtD)
ASEACPL_6424
AMSAMIS_61670
ACTNL083_5287 L083_7398
AFSAFR_38625
ACTSACWT_6291
AIHAiant_21050(egtD)
ACTRAsp14428_55950(egtD)
PLKCIK06_14635(egtD)
PLABC6361_00300 C6361_04525(egtD)
PLATC6W10_01050(egtD) C6W10_21350
PFLAPflav_033920(egtD)
PSUUPsuf_076980(egtD)
ATLAthai_00980(egtD)
ASERAsera_06490(egtD)
CATICS0771_27270(egtD)
DVCDvina_39830(egtD)
DFUDfulv_30250(egtD)
DROSDrose_22740(egtD)
DAURDaura_38940(egtD)
DMATDmats_34710(egtD)
NHYJQS43_04875(egtD)
CCAZCOUCH_05015(egtD)
CAICaci_8031
SNASnas_5171 Snas_5803
NAVJQS30_12780(egtD)
GLYK3N28_07610(egtD) K3N28_10175(egtD)
AEYCDG81_09260(egtD)
EKEEK0264_15145(egtD)
RXYRxyl_0685
RUBGBA63_15145(egtD)
RMARGBA65_19465(egtD)
BSOLFSW04_08720(egtD)
CWOCwoe_4694
PARNNBH00_09420(egtD)
SBAEDSM104329_01348(egtD)
IAMHC251_03785(egtD)
EUZDVS28_a3893
SYPSYNPCC7002_G0154
SYNDKR52_01880
SYHSyncc8109_0137
SYVAWQ23_15405
SYLAWQ21_15715
PMTPMT_0151
CMPCha6605_0924 Cha6605_6115
TVNNIES2134_106700
SLWBRW62_12105
THECFFX45_11880(egtD)
LENLEP3755_31680
LBOLBWT_13420 LBWT_55940
HHGXM38_007130(egtD)
PSERABRG53_3845
GENGM3709_2693
GEEGM3708_149
CHONNIES4102_00650
MPKVL20_3603
MIQB5D77_07710
MVZmyaer102_16740
CYLAA637_04885(egtD)
CWACwatDRAFT_0669
TERTery_0701
PAGHNIES204_04670
OXYHCG48_02440(egtD)
NONNOS3756_18750
NFLCOO91_06060
NOECLI64_23850(egtD)
NSHGXM_06079
NEDHUN01_13950(egtD) HUN01_34300(egtD)
AWAAA650_10900
ANNEH233_01630(egtD)
RSINB6N60_02309
CALHIJ00_06490
FISFIS3754_37670
DOUBMF77_04280(egtD)
DFSHGD76_19445(egtD)
CCURIAR63_17435(egtD)
AFLOHEQ12_04420(egtD)
TOQHCG51_33475(egtD)
NCNBZZ01_15770
ROOG5S37_03015
MEAPMTHMO_2343
IPAIsop_1456
AGVOJF2_75020
KSTKSMBR1_0240
JETL3J17_13845(egtD)
ALUSSTSP2_03355(egtD)
GRWFTO74_14805(egtD)
GRBGOB94_11770(egtD)
TALBFTW19_05985(egtD)
ABASACPOL_0188
EDAGWR55_18315(egtD)
EDGH7846_05980(egtD)
ADINH7849_05225(egtD)
ORPMOP44_07125(egtD)
PFERIRI77_13455(egtD) IRI77_22240(egtD)
ABACLuPra_04570(egtD)
GBAJ421_1882
DRCG0Q07_15200
CPICpin_4447 Cpin_4965
CHITFW415_12130(egtD)
CHIHGWR21_00275
CFILMYF79_15200
ATEEK9M52_02965
FLNFLA_2378
HHYHalhy_2585
PEPAQ505_15340
PCMAY601_2311
PEKFFJ24_009340
PROEH9L23_11640
SHGSph21_2565
SHTKO02_15555
SPHNBV902_12545
SMUII6J00_01530
MUPA0256_07290
MUCMuYL_0155
MUHHYN43_022905
MGINFRZ54_04635(egtD)
MGKFSB76_15585
MRUBDEO27_024390
MGOSDIU38_025485
MMABHQ865_22855
MGIKGO620_012470
AGDFRZ59_14650
OLIFKG96_10190
CMRCycma_1973
CAMUCA2015_1910
ECHIFKX85_05685 FKX85_14085(egtD)
SLISlin_6101
SRDSD10_22655
SMONAWR27_04340
SPIRCWM47_26965(egtD)
SPIKEXU85_31130(egtD)
SPIBG8759_33700(egtD)
STAEHNV11_02835(egtD)
RHOZGXP67_11005(egtD)
DFEDfer_1252
FIBA6C57_03350
ALSDJ013_18510(egtD)
HSWHsw_2886
HYDPK28_12240
HYEAM218_04215
HYGAUC43_12115
HYPA0257_00755
HYZAXW84_13805
HNVDDQ68_08390(egtD)
HYHD3Y59_01875(egtD)
HYJFHG12_15230(egtD)
HQIH9L05_13610
HRSHER32_03815(egtD)
HBNGUY19_00185(egtD)
PKOPKOR_03290 PKOR_17700
PACTCA264_06360
RUFTH63_08500
RTIDC20_20060
RUDTH61_14095
NIBGU926_01585(egtD)
ADDHUW48_10820(egtD)
ASWUHUW51_18210(egtD)
FPFDCC35_11840
FLMMY04_3419(egtD)
FLLEI427_19140(egtD)
FYAKMW28_19645(egtD)
FKAKM029_12135(egtD)
FBTD770_20210
CHKD4L85_23840(egtD)
GFOGFO_0284
GRLLPB144_07785
GRSC7S20_07230(egtD) C7S20_09335(egtD)
FPSZAMR72_10505
FFAFFWV33_03980
FATDVK85_06410
FKIFK004_03995
FALBHYN59_04110(egtD)
FAKFUA48_04405
FLOK1I41_03580
RBIRB2501_03225
ZPRZPR_3669
CATCA2559_13323
MARMYQ22_04400
MARTBTR34_04565
MARBCJ263_13035(egtD)
MAREEJ994_00390
CAOCelal_4080
CLYCelly_3136
CLHIX49_15855
CBALM667_16770
CBATM666_16790
KDIKrodi_0782
DOKMED134_00085
DDOI597_0250(egtD)
DODDCS32_08115
LANLacal_2554
LVNBWR22_12070
ZGAZOBELLIA_872
MLTVC82_2021
SPONHME9304_02218(egtD)
ASLAeqsu_0715
AEVEI546_15300
AICJK629_02930
PTQP700755_003062
NDODDD_1043
NOMAAT17_05470
NSDBST91_00410
NOBCW736_06240
NOJEJ995_04110
POMMED152_03665
POBLPB03_03815
POLABXQ17_02435
AHZAPS56_15390
SYISB49_15115
FOPFNB79_11360
SALTAO058_01100
SMISLDL76_08135
SEONBWZ22_14315
AALGAREALGSMS7_03795(egtD)
OLLCW732_14405
OAQDZC78_03490
AUEC5O00_03170
AQBD1818_10675(egtD)
AQAD1815_20260(egtD)
AQDD1816_12085
EMARD1013_05185
PSYNE9099_14785
AFLAFHG64_05855
ANPFK178_09555
MGELG5B37_11835
GAAHX109_09310
CAGGHYG79_03660(egtD)
ALTIALE3EI_1337
MARXINR76_02015
FLGLV716_03675
FLBLV704_04555
BIAGMA17_10805
CIOCEQ15_10625(egtD)
CHRYCEY12_01740
CPIPCJF12_06060
CSHAEG350_11215(egtD)
CILEG358_16925
CCAUEG346_14120(egtD)
CGLENCTC11432_01867(egtD)
CLACEG342_21865(egtD)
CSALNBC122_00935(egtD)
CJGNCTC13459_02067(egtD)
CCASEIB73_10320
CANTNCTC13489_02180(egtD)
KDAEIB71_04545
FTEFluta_3843
OHOOweho_0985
CPBCphamn1_1309
CLIClim_1148
PROSCHL67_06190(egtD)
MMHMmah_1747
MHAZBHR79_04945
MZHMzhil_1067
MPYMpsy_2947
MZIHWN40_01430(egtD)
NIRNSED_03365
NKRNKOR_03390
NIDNPIRD3C_1612
NIWNisw_01635(egtD)
NCLC5F47_05795(egtD)
NOXC5F49_05645(egtD)
NUEC5F50_04790(egtD)
NCTNMSP_1036
NICDSQ20_03505(egtD)
CSYCENSYa_0372
TAANMY3_02528(egtD)
NBVT478_0971(egtD)
 » show all
Reference
1  [PMID:5484456]
  Authors
Ishikawa Y, Melville DB.
  Title
The enzymatic alpha-N-methylation of histidine.
  Journal
J Biol Chem 245:5967-73 (1970)
DOI:10.1016/S0021-9258(18)62649-3
Reference
2  [PMID:20420449]
  Authors
Seebeck FP
  Title
In vitro reconstitution of Mycobacterial ergothioneine biosynthesis.
  Journal
J Am Chem Soc 132:6632-3 (2010)
DOI:10.1021/ja101721e
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.44
IUBMB Enzyme Nomenclature: 2.1.1.44
ExPASy - ENZYME nomenclature database: 2.1.1.44
BRENDA, the Enzyme Database: 2.1.1.44
CAS: 62213-53-0

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