Entry
Name
calmodulin-lysine N-methyltransferase;
S-adenosylmethionine:calmodulin (lysine) N-methyltransferase;
S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine [RN:
R04062 ]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:
C00019 ];
calmodulin L-lysine [CPD:
C02816 ]
Product
S-adenosyl-L-homocysteine [CPD:
C00021 ];
calmodulin N6-methyl-L-lysine [CPD:
C03941 ]
Comment
One of a group of enzymes methylating proteins; see also the family of histone-lysine N-methyltransferases (previously EC
2.1.1.43 ) and EC
2.1.1.59 [cytochrome c]-lysine N-methyltransferase.
History
EC 2.1.1.60 created 1982, modified 1983
Pathway
Orthology
K18826 calmodulin-lysine N-methyltransferase
Genes
AMJ : 102565761(CAMKMT) 106737962
SANH : 107666367 107698723
CCAR : 109070974 109100918
CGIB : 127970047 128026311
ALIM : 106534025(camkmt) 106536025
PSPA : 121316347 121316678(camkmt)
DME : Dmel_CG10947(CG10947)
DSI : Dsimw501_GD21704(Dsim_GD21704)
AALB : 109430182 109433596
CSAT : 104716521 104721174 104729584
BNA : 106348177 106446057 125597586
HSYR : 120121604 120141667 120216274
CSAV : 115696580 115716842
QLO : 115950945 115951017 115969508
CANN : 107868190 107869094
NTA : 107773212 107795679 107831011
SSPL : 121747939 121785914
SMIL : 131023841 131023963
PSOM : 113330559 113357170
TAES : 123085189 123092787 123098086
MFLO : 136532621 136534698 136548320 136548896
PVIR : 120646682 120691034
PAUA : 133912030 133916535
SMO : SELMODRAFT_112177 SELMODRAFT_78185
» show all
Taxonomy
Reference
Authors
Sitaramayya A, Wright LS, Siegel FL.
Title
Enzymatic methylation of calmodulin in rat brain cytosol.
Journal
J Biol Chem 255:8894-900 (1980)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.60
ExPASy - ENZYME nomenclature database: 2.1.1.60