 | | ENZYME: 2.1.1.88 | |
| Entry |
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| Name |
8-hydroxyquercetin 8-O-methyltransferase;
flavonol 8-O-methyltransferase;
flavonol 8-methyltransferase;
S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase;
8-hydroxyquercitin 8-O-methyltransferase [mis-spelt]
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:3,5,7,8,3',4'-hexahydroxyflavone 8-O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + 3,5,7,8,3',4'-hexahydroxyflavone = S-adenosyl-L-homocysteine + 3,5,7,3',4'-pentahydroxy-8-methoxyflavone [RN: R04398]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
3,5,7,8,3',4'-hexahydroxyflavone
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
3,5,7,3',4'-pentahydroxy-8-methoxyflavone
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| Comment |
Also acts on 8-hydroxykaempferol, but not on the glycosides of 8-hydroxyflavonols. An enzyme from the flower buds of Lotus corniculatus.
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| History |
EC 2.1.1.88 created 1989
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| Reference |
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| Authors |
Jay M, De Luca V, Ibrahim RK. |
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| Title |
Purification, properties and kinetic mechanism of flavonol 8-O-methyltransferase from Lotus corniculatus L. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.1.1.88 |
| ExPASy - ENZYME nomenclature database: | 2.1.1.88 |
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