KEGG   ENZYME: 2.1.1.94Help
Entry
EC 2.1.1.94                 Enzyme                                 

Name
tabersonine 16-O-methyltransferase;
11-demethyl-17-deacetylvindoline 11-methyltransferase;
11-O-demethyl-17-O-deacetylvindoline O-methyltransferase;
S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 16-hydroxytabersonine = S-adenosyl-L-homocysteine + 16-methoxytabersonine [RN:R05885]
Reaction(KEGG)
R05885;
(other) R03229
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Substrate
S-adenosyl-L-methionine [CPD:C00019];
16-hydroxytabersonine [CPD:C11643]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
16-methoxytabersonine [CPD:C11675]
Comment
Involved in the biosynthesis of vindoline from tabersonine in the Madagascar periwinkle, Catharanthus roseus.
History
EC 2.1.1.94 created 1989, modified 2005
Pathway
ec00901  Indole alkaloid biosynthesis
Orthology
K21895  tabersonine 16-O-methyltransferase
Reference
1
  Authors
De Luca, V., Balsevich, J., Tyler, R.T., Eilert, U., Panchuk, B.D. and Kurz, W.G.W.
  Title
Biosynthesis of indole alkaloids - developmental regulation of the biosynthetic-pathway from tabersonine to vindoline in Catharanthus roseus.
  Journal
J Plant Physiol 125:147-156 (1986)
Reference
2  [PMID:24254077]
  Authors
Fahn W, Laussermair E, Deus-Neumann B, Stockigt J
  Title
Late enzymes of vindoline biosynthesis : S-Adenosyl-L-methionine: 11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase and unspecific acetylesterase.
  Journal
Plant Cell Rep 4:337-40 (1985)
DOI:10.1007/BF00269893
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.94
IUBMB Enzyme Nomenclature: 2.1.1.94
ExPASy - ENZYME nomenclature database: 2.1.1.94
BRENDA, the Enzyme Database: 2.1.1.94
CAS: 100984-95-0

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