Entry |
|
Name |
3-hydroxyanthranilate 4-C-methyltransferase;
3-hydroxyanthranilate 4-methyltransferase
|
Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
|
Sysname |
S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase
|
Reaction(IUBMB) |
S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate [RN: R02667]
|
Reaction(KEGG) |
|
Substrate |
S-adenosyl-L-methionine [CPD: C00019];
3-hydroxyanthranilate [CPD: C00632]
|
Product |
S-adenosyl-L-homocysteine [CPD: C00021];
3-hydroxy-4-methylanthranilate [CPD: C03986]
|
Comment |
Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus.
|
History |
EC 2.1.1.97 created 1990
|
Reference |
|
Authors |
Fawaz F, Jones GH. |
Title |
Actinomycin synthesis in Streptomyces antibioticus. Purification and properties of a 3-hydroxyanthranilate 4-methyltransferase. |
Journal |
J Biol Chem 263:4602-6 (1988) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.1.1.97 |
ExPASy - ENZYME nomenclature database: | 2.1.1.97 |
|