KEGG   ENZYME: 2.2.1.14
Entry
EC 2.2.1.14                 Enzyme                                 

Name
6-deoxy-6-sulfo-D-fructose transaldolase;
sftT (gene name)
Class
Transferases;
Transferring aldehyde or ketonic groups;
Transketolases and transaldolases
Sysname
6-deoxy-6-sulfo-D-fructose:D-glyceraldehyde-3-phosphate glyceronetransferase
Reaction(IUBMB)
6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate = (2S)-3-sulfolactaldehyde + beta-D-fructofuranose 6-phosphate [RN:R12731]
Reaction(KEGG)
R12731
Substrate
6-deoxy-6-sulfo-D-fructose [CPD:C20830];
D-glyceraldehyde 3-phosphate [CPD:C00118]
Product
(2S)-3-sulfolactaldehyde [CPD:C21181];
beta-D-fructofuranose 6-phosphate [CPD:C05345]
Comment
The enzyme, characterized from the bacterium Bacillus aryabhattai SOS1, is involved in a degradation pathway for 6-sulfo-D-quinovose. The enzyme can also use D-erythrose 4-phosphate as the acceptor, forming D-sedoheptulose 7-phosphate.
History
EC 2.2.1.14 created 2021
Orthology
K00617  6-deoxy-6-sulfo-D-fructose transaldolase
Genes
BWH: A9C19_00910
BHK: B4U37_05740
BMQ: BMQ_3648
BMH: BMWSH_1555(talC)
BMUR: ABE28_009840
MEKU: HUW50_07770
MSEM: GMB29_25460
LZY: LZ3411_1762 LZ3411_1862
LSUA: H3M12_11825
LHO: LOOC260_121250(tal)
LOL: LACOL_0643(tal1)
ERT: EUR_25510
GMR: GmarT_58970(tal_2)
GPN: Pan110_58800(tal_2)
MRI: Mal4_33870(tal_2)
BPW: WESB_2478
TNA: CTN_1544
 » show all
Reference
1  [PMID:32919372]
  Authors
Frommeyer B, Fiedler AW, Oehler SR, Hanson BT, Loy A, Franchini P, Spiteller D, Schleheck D.
  Title
Environmental and Intestinal Phylum Firmicutes Bacteria Metabolize the Plant Sugar Sulfoquinovose via a 6-Deoxy-6-sulfofructose Transaldolase Pathway.
  Journal
iScience 23:101510 (2020)
DOI:10.1016/j.isci.2020.101510
Other DBs
ExplorEnz - The Enzyme Database: 2.2.1.14
IUBMB Enzyme Nomenclature: 2.2.1.14
ExPASy - ENZYME nomenclature database: 2.2.1.14
BRENDA, the Enzyme Database: 2.2.1.14

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