KEGG   ENZYME: 2.3.1.122
Entry
EC 2.3.1.122                Enzyme                                 

Name
trehalose O-mycolyltransferase;
alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase;
alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
alpha,alpha-trehalose-6-mycolate:alpha,alpha-trehalose-6-mycolate 6'-mycolyltransferase
Reaction(IUBMB)
2 alpha,alpha-trehalose 6-mycolate = alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate [RN:R07248]
Reaction(KEGG)
R07248
Substrate
alpha,alpha'-trehalose 6-mycolate [CPD:C04218]
Product
alpha,alpha-trehalose [CPD:C01083];
alpha,alpha'-trehalose 6,6'-bismycolate [CPD:C04465]
Comment
Catalyses the exchange of mycolic acid between trehalose, trehalose mycolate and trehalose bismycolate. Trehalose 6-palmitate can also act as donor.
History
EC 2.3.1.122 created 1990
Pathway
ec00572  Arabinogalactan biosynthesis - Mycobacterium
Orthology
K18851  diacylglycerol O-acyltransferase / trehalose O-mycolyltransferase
Genes
MTU: Rv0129c(fbpC) Rv1886c(fbpB) Rv3804c(fbpA)
MTV: RVBD_0129c RVBD_1886c RVBD_3804c
MTC: MT0137(fbpC) MT1934(fbpB) MT3911(fbpA)
MRA: MRA_0136(fbpC) MRA_1897(fbpB) MRA_3844(fbpA)
MTF: TBFG_10130 TBFG_11914 TBFG_13838
MTB: TBMG_00130 TBMG_02108 TBMG_03851
MTK: TBSG_00131 TBSG_02119 TBSG_03874
MTZ: TBXG_000130 TBXG_002090 TBXG_003821
MTG: MRGA327_00840 MRGA327_23425
MTI: MRGA423_00845 MRGA423_11765 MRGA423_24000
MTUR: CFBS_0139(fbpC) CFBS_1978(fbpB) CFBS_4033(fbpA)
MTO: MTCTRI2_0132(fbpC) MTCTRI2_1918(fbpB) MTCTRI2_3883(fbpA)
MTD: UDA_0129c(fbpC) UDA_1886c(fbpB) UDA_3804c(fbpA)
MTN: ERDMAN_0150(fbpC) ERDMAN_2078(fbpB) ERDMAN_4170(fbpA)
MTUT: HKBT1_0139(fbpC) HKBT1_1975(fbpB) HKBT1_4016(fbpA)
MTUU: HKBT2_0139(fbpC) HKBT2_1983(fbpB) HKBT2_4026(fbpA)
MTQ: HKBS1_0139(fbpC) HKBS1_1979(fbpB) HKBS1_4029(fbpA)
MBB: BCG_0163c(fbpC) BCG_1923c(fbpB) BCG_3866c(fbpA)
MBT: JTY_0133(fbpC) JTY_1907(fbpB) JTY_3868(fbpA)
MBM: BCGMEX_0133c(fbpC) BCGMEX_1904c(fbpB) BCGMEX_3867c(fbpA)
MAF: MAF_01290(fbpC) MAF_19080(fbpB) MAF_38190(fbpA)
MCE: MCAN_01321(fbpC) MCAN_19011(fbpB) MCAN_38231(fbpA)
MCQ: BN44_10156(fbpC) BN44_120211(fbpA) BN44_40149(fbpB)
MCV: BN43_10150(fbpC) BN43_31028(fbpB) BN43_90319(fbpA)
MCX: BN42_10168(fbpC) BN42_30153(fbpB) BN42_90327(fbpA)
MCZ: BN45_10146(fbpC) BN45_110165(fbpA) BN45_50153(fbpB)
MLE: ML0097(fbpA) ML2028(fbpB) ML2655(fbpC2)
MLB: MLBr00097(fbpA) MLBr02028(fbpB) MLBr02655(fbpC2)
MPA: MAP_0216(fbpA) MAP_1609c(fbpB) MAP_3531c(fbpC2)
MUL: MUL_2970(fbpB) MUL_4793(fbpC) MUL_4987(fbpA)
MMI: MMAR_0328(fbpC) MMAR_2777(fbpB) MMAR_4556(fbpC_2) MMAR_5368(fbpA)
MMAE: MMARE11_02980(fbpC) MMARE11_26980(fbpB) MMARE11_43690(fbpC_2) MMARE11_51890(fbpA)
MLI: MULP_00305(fbpC) MULP_02535(fbpB) MULP_04773(fbpC_2) MULP_05647(fbpA)
MSHG: MSG_00258(fbpC) MSG_02673(fbpB) MSG_04876(fbpA)
MFJ: MFLOJ_05560(fbpB) MFLOJ_32520(fbpC) MFLOJ_36480(fbpA)
MXE: MYXE_02430(fbpA) MYXE_25070(fbpB) MYXE_46510 MYXE_47940(fbpC)
MNV: MNVI_15420(fbpA) MNVI_18110(fbpC) MNVI_41460(fbpB)
MNM: MNVM_20020(fbpC) MNVM_20620(fbpA) MNVM_29820(fbpB_1) MNVM_40800(fbpB_2)
MCOO: MCOO_09690(fbpB) MCOO_30380(fbpA) MCOO_34030(fbpC)
MPHL: MPHLCCUG_00201(fbpC_1) MPHLCCUG_00202(fbpB_1) MPHLCCUG_01766(fbpB_2) MPHLCCUG_02396(fbpC_3) MPHLCCUG_04293(fbpB_3)
MTHN: 4412656_01363(fbpB) 4412656_02288(fbpC_2) 4412656_02315(fbpC_3) 4412656_03604(fbpC_4) 4412656_04405(fbpC_5) 4412656_04406(fbpA_2)
MHAS: MHAS_00109(fbpC_1) MHAS_00637(fbpB_1) MHAS_01844(fbpC_3) MHAS_01874(fbpC_4) MHAS_04493(fbpB_2)
MDU: MDUV_11680(fbpC_1) MDUV_12510 MDUV_26150(fbpB_1) MDUV_34970 MDUV_45820(fbpB_2)
MAUU: NCTC10437_00970(fbpC_1) NCTC10437_01234(fbpC_2) NCTC10437_01709(fbpA_1) NCTC10437_02819(fbpC_3) NCTC10437_02956(fbpC_4) NCTC10437_05407(fbpA_3)
MMAG: MMAD_06310(fbpA) MMAD_09960(fbpC) MMAD_17330(fbpB_1) MMAD_29960 MMAD_51750(fbpB_2) MMAD_52850
MSAL: DSM43276_00152(fbpC_1) DSM43276_00153(fbpA_1) DSM43276_00154(fbpA_2)
MJD: JDM601_1973(fbpB) JDM601_3084(fbpB) JDM601_4122(fbpA) JDM601_4182(fbpC)
MTER: 4434518_01923(fbpB_1) 4434518_03072(fbpB_2) 4434518_04061(fbpA) 4434518_04119(fbpC)
MMIN: MMIN_15580(fbpB_1) MMIN_16220(fbpC) MMIN_36120(fbpB_2)
MHIB: MHIB_14450(fbpB_1) MHIB_25150(fbpB_2) MHIB_34440(fbpA) MHIB_34990(fbpC)
MKR: MKOR_07710(fbpB) MKOR_23830 MKOR_29930(fbpC) MKOR_32900(fbpA)
CGB: cg3186(cmt2)
CGU: WA5_2779(Cmt2)
CGT: cgR_2766
CGM: cgp_3186(cmt2)
CGJ: AR0_13980
CEF: CE2710
CDP: CD241_2083(cmtB)
CDH: CDB402_2058(cmtB)
CDT: CDHC01_2084(cmtB)
CDE: CDHC02_2078(cmtB)
CDR: CDHC03_2080(cmtB)
CDA: CDHC04_2110(cmtB)
CDZ: CD31A_2214(cmtB)
CDB: CDBH8_2170(cmtB)
CDS: CDC7B_2176(cmtB)
CDD: CDCE8392_2098(cmtB)
CDW: CDPW8_2159(cmtB)
CDV: CDVA01_2006(cmtB)
CDIP: ERS451417_02229(cmtB)
CJK: jk0133(cmtB)
CUR: cu0155
CKP: ckrop_0238(cmtA) ckrop_0824(cmtC)
CRD: CRES_0530(cmtB)
CUL: CULC22_02192(cmtB)
CUC: CULC809_02040(cmtB)
CUE: CULC0102_2184(cmtB)
CUN: Cul210932_2170(cmtB)
CUS: CulFRC11_2062(cmtB)
CUQ: Cul210931_2124(cmtB)
CUZ: Cul05146_2162(cmtB)
CUJ: CUL131002_2079c(cmtB)
CVA: CVAR_0244(cmtC) CVAR_0249(cmtE) CVAR_2771
CTER: A606_01010
CGV: CGLAU_01060(fbpA2) CGLAU_05725(fbpB1) CGLAU_05730(fbpB2) CGLAU_11465(fbpC2)
CPEG: CPELA_00925(fbpC1)
CEE: CENDO_01385(fbpA1) CENDO_01390(fbpB1) CENDO_09560 CENDO_10600(fbpB2)
CGK: CGERO_00925(fbpC1)
CRL: NCTC7448_00622(fbpC)
CCHO: CCHOA_00080(fbpC1) CCHOA_00600(fbpC2)
CPRE: Csp1_25030(fbpB_2)
CPSO: CPPEL_00860(fbpC)
CSUR: N24_2978
RFA: A3L23_00910(fbpC_2) A3L23_01133(fbpA_2) A3L23_02025(fbpB_1) A3L23_02026(fbpB_2) A3L23_02215(fbpA_4) A3L23_02722(fbpA_5)
RHS: A3Q41_00640(fbpA_2) A3Q41_01171(fbpA_3) A3Q41_01337(fbpB_3) A3Q41_01338(fbpB_4) A3Q41_02253(fbpA_6) A3Q41_02441(fbpC_1)
RHU: A3Q40_00461(fbpC) A3Q40_00508(fbpA_1) A3Q40_03644(fbpB)
RRT: 4535765_00216(fbpC_1) 4535765_00853(fbpC_2) 4535765_02525(fbpA_2) 4535765_03072(fbpA_3) 4535765_03504(fbpA_4)
GRU: GCWB2_00940(fbpC1) GCWB2_00945(fbpC2) GCWB2_01195(fbpA1) GCWB2_01225(fbpB1) GCWB2_03375(fbpA2) GCWB2_03660(fbpA3) GCWB2_04020(fbpA4) GCWB2_04590(fbpC3) GCWB2_06095 GCWB2_07975(fbpA6) GCWB2_18875(fbpA8) GCWB2_20545(fbpA9) GCWB2_22675(fbpA11)
GOM: D7316_01430(fbpA_3) D7316_01658(fbpA_4) D7316_03053(fbpC_1) D7316_03353(fbpB_1) D7316_03360(fbpB_2) D7316_03457(fbpA_6) D7316_03458(fbpC_2) D7316_03539(fbpA_7) D7316_04712(fbpC_3) D7316_04906(fbpB_3) D7316_04985(fbpA_8) D7316_05278(fbpB_4)
SALS: SLNWT_5536
STRD: NI25_05335
SMAL: SMALA_4346
SALJ: SMD11_0769
SGE: DWG14_08024(fbpA)
BLIN: BLSMQ_1071
TCU: Tcur_1216
FAL: FRAAL5369
AMN: RAM_22840
AMM: AMES_4430
AMZ: B737_4430
AOI: AORI_4816
AMYY: YIM_26405(fbpB1) YIM_32785(fbpA1)
AORI: SD37_23810
AMI: Amir_1031
KAL: KALB_8326
 » show all
Reference
1  [PMID:3654621]
  Authors
Sathyamoorthy N, Takayama K.
  Title
Purification and characterization of a novel mycolic acid exchange enzyme from Mycobacterium smegmatis.
  Journal
J Biol Chem 262:13417-23 (1987)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.122
IUBMB Enzyme Nomenclature: 2.3.1.122
ExPASy - ENZYME nomenclature database: 2.3.1.122
BRENDA, the Enzyme Database: 2.3.1.122
CAS: 111694-11-2

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