KEGG   ENZYME: 2.3.1.125
Entry
EC 2.3.1.125                Enzyme                                 
Name
1-alkyl-2-acetylglycerol O-acyltransferase;
1-hexadecyl-2-acetylglycerol acyltransferase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase
Reaction(IUBMB)
acyl-CoA + 1-O-alkyl-2-acetyl-sn-glycerol = CoA + 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol [RN:R04363]
Reaction(KEGG)
R04363
Substrate
acyl-CoA [CPD:C00040];
1-O-alkyl-2-acetyl-sn-glycerol [CPD:C03820]
Product
CoA [CPD:C00010];
1-O-alkyl-2-acetyl-3-acyl-sn-glycerol [CPD:C04361]
Comment
A number of acyl-CoAs can act as acyl donor; maximum activity is obtained with linoleoyl-CoA. Not identical with EC 2.3.1.20 diacylglycerol O-acyltransferase.
History
EC 2.3.1.125 created 1990
Pathway
ec00565  Ether lipid metabolism
Reference
1  [PMID:3422635]
  Authors
Kawasaki T, Snyder F.
  Title
Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells.
  Journal
J Biol Chem 263:2593-6 (1988)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.125
IUBMB Enzyme Nomenclature: 2.3.1.125
ExPASy - ENZYME nomenclature database: 2.3.1.125
BRENDA, the Enzyme Database: 2.3.1.125
CAS: 114704-90-4

  All links  
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
All databases (9)   

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