KEGG ENZYME: 2.3.1.13

ENZYME: 2.3.1.13

Entry

EC 2.3.1.13 Enzyme

Name

glycine N-acyltransferase;
glycine acyltransferase;
glycine-N-acylase

Class

Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups

Sysname

acyl-CoA:glycine N-acyltransferase

Reaction(IUBMB)

acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395]

Reaction(KEGG)

R00395

Substrate

acyl-CoA [CPD:C00040];
glycine [CPD:C00037]

Product

CoA [CPD:C00010];
N-acylglycine [CPD:C02055]

Comment

The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC 2.3.1.68 glutamine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.

History

EC 2.3.1.13 created 1961

Orthology

K00628

glycine N-acyltransferase / glycine N-benzoyltransferase

K22749

glycine N-acyltransferase

Genes

HSA:	10249(GLYAT) 219970(GLYATL2)

PTR:	451206(GLYATL2) 748398(GLYAT)

PPS:	100979655(GLYATL2) 100980359(GLYAT)

GGO:	101124654(GLYAT) 101125629

PON:	100173810(GLYAT) 100443306

NLE:	100588653 100593268(GLYATL2) 100593830

MCC:	701659(GLYAT)

MCF:	102146442(GLYAT) 102146816

CSAB:

103235080(GLYAT)

RRO:	104680418(GLYAT)

RBB:	108541348(GLYAT)

CJC:	100395000(GLYAT) 100395366(GLYATL2)

SBQ:	101033622(GLYAT) 101033935(GLYATL2)

MMU:	107146(Glyat) 64697(Keg1)

RNO:	171179(Glyatl2) 293779(Glyat)

MUN:	110565447 110565760

CGE:	100774147 100774433 113831596

NGI:	103733343 103733398

HGL:	101711412 101712854 101713466(Glyat)

CCAN:

109678086

OCU:	100345309(GLYAT)

TUP:	102485105 102488756(GLYAT) 102500544(GLYATL2)

CFA:	483463(GLYAT)

AML:

100476924

UMR:	103666140(GLYAT) 103666271(GLYATL2)

ORO:	101370241(GLYAT) 101370831

FCA:	101094699(GLYATL2) 101097840(GLYAT)

PTG:	102966010(GLYAT) 102966774(GLYATL2)

AJU:	106986792(GLYATL2) 106986793

BTA:	104974345 281787(GLYAT) 515352(GLYATL2) 518623

BOM:	102270060 102270337 102274551(GLYATL2) 102284395

BIU:	109569442(GLYATL2) 109569864 109569929 109569937

PHD:	102338225(GLYAT) 102338579 102339524(GLYATL2)

CHX:	102175500 102176061 102176349(GLYATL2)

OAS:	101108419 101108685(GLYAT) 101109387(GLYATL2)

SSC:	100518109 100518644 100525206(GLYATL2)

CFR:	102511836(GLYATL2) 102512308 102523093

CDK:	105094918(GLYATL2) 105094920 105094922

BACU:

103012684(GLYAT) 103013536

LVE:	103084960 103085242

OOR:	101286759 101287020

DLE:	111183924 111183925

ECB:	100066603 100068374

EPZ:	103556884 103556886

EAI:	106825141 106825142

MYB:	102246796 102250190 102250899(GLYATL2) 102252075

MYD:	102767900(GLYAT) 102768179 102769546 102770418(GLYATL2)

MNA:	107527657(GLYATL2) 107527658(GLYAT)

HAI:	109389993(GLYAT) 109390041(GLYATL2)

RSS:	109438812(GLYAT) 109439517 109439518(GLYATL2)

PALE:

102891747 102895685

LAV:	100662425 100662985 100663214 100668301(GLYAT) 100668589 104847055

TMU:	101350172 101357009

MDO:	100027219(GLYAT) 100027341

SHR:	100915893 100916236 100916412 100916499 100916674 100918927(GLYAT)

PCW:	110200706 110200708 110200793

OAA:

100081664

NPR:

108798821

» show all

Reference

1 [PMID:457678]

Authors

Nandi DL, Lucas SV, Webster LT Jr.

Title

Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.

Journal

J Biol Chem 254:7230-7 (1979)

Sequence

[bta:281787]

Reference

2 [PMID:13174534]

Authors

SCHACHTER D, TAGGART JV.

Title

Glycine N-acylase: purification and properties.

Journal

J Biol Chem 208:263-75 (1954)

Reference

3 [PMID:931988]

Authors

Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ.

Title

Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man.

Journal

J Biol Chem 251:3352-8 (1976)

Other DBs

ExplorEnz - The Enzyme Database:

2.3.1.13

IUBMB Enzyme Nomenclature:

2.3.1.13

ExPASy - ENZYME nomenclature database:

2.3.1.13

BRENDA, the Enzyme Database:

2.3.1.13

CAS:

9029-95-2

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