KEGG   ENZYME: 2.3.1.13
Entry
EC 2.3.1.13                 Enzyme                                 
Name
glycine N-acyltransferase;
glycine acyltransferase;
glycine-N-acylase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acyl-CoA:glycine N-acyltransferase
Reaction(IUBMB)
acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395]
Reaction(KEGG)
R00395
Substrate
acyl-CoA [CPD:C00040];
glycine [CPD:C00037]
Product
CoA [CPD:C00010];
N-acylglycine [CPD:C02055]
Comment
The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC 2.3.1.68 glutamine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.
History
EC 2.3.1.13 created 1961
Orthology
K00628  glycine N-acyltransferase / glycine N-benzoyltransferase
K22749  glycine N-acyltransferase
Genes
HSA: 10249(GLYAT) 219970(GLYATL2)
PTR: 451206(GLYATL2) 748398(GLYAT)
PPS: 100979655(GLYATL2) 100980359(GLYAT)
GGO: 101124654(GLYAT) 101125629
PON: 100173810(GLYAT) 100443306(GLYATL2) 100448068
PPYG: 129008206 129008356
NLE: 100588653 100593268(GLYATL2) 100593830
HMH: 116468207(GLYATL2) 116468815(GLYAT)
SSYN: 129475448(GLYAT) 129478408(GLYATL2)
MCC: 114672254 701659(GLYAT)
MCF: 102146442(GLYAT)
MTHB: 126936171
MNI: 105496094(GLYAT)
CSAB: 103235080(GLYAT)
CATY: 105600759(GLYAT)
PANU: 101001949(GLYAT)
TGE: 112606476(GLYAT)
MLEU: 105530757(GLYAT)
RRO: 104680418(GLYAT)
RBB: 108541348(GLYAT)
TFN: 117080716(GLYAT)
PTEH: 111544978(GLYAT)
CANG: 105527196(GLYAT)
CJC: 100395000(GLYAT) 100395366(GLYATL2)
SBQ: 101033622(GLYAT) 101033935(GLYATL2)
CIMI: 108282878(GLYATL2) 108282879(GLYAT)
ANAN: 105730323(GLYATL2) 105730324(GLYAT)
CSYR: 103253803(GLYATL2) 103269914 103269915
MMUR: 105863123(GLYATL2) 105863143
LCAT: 123642731 123642734(GLYATL2)
PCOQ: 105810009(GLYATL2) 105810068
OGA: 100944583(GLYAT) 100958233 100958553 100959183(GLYATL2)
MMU: 107146(Glyat) 64697(Keg1)
MCAL: 110285861(Glyat) 110285927
MPAH: 110333589 110334444
RNO: 171179(Glyatl2) 293779(Glyat)
MCOC: 116101066 116101070
ANU: 117721946 117723317
ASYL: 127667303 127689537
MUN: 110565447 110565760
CGE: 100774147 100774433 100774725
MAUA: 101831003 101841125
PROB: 127228904 127228906
PLEU: 114703386 114703387
MORG: 121454269(Glyat) 121454334 121454336 121454473 121454631
MFOT: 126498309 126498312 126498313 126498314 126498315
AAMP: 119811672 119812880 119812899 119812916
NGI: 103733343 103733398
HGL: 101711412 101712854 101713466(Glyat)
CPOC: 100730253 100733575
CCAN: 109678086
DORD: 105995257 105995531
DSP: 122104903 122104904
DMER: 138833869
PLOP: 125362689 125362690
NCAR: 124958958 124960038
MMMA: 107135854 107135857(Glyat)
ITI: 101960208 101961074
OCU: 100345309
OPI: 101532529
TUP: 102485105 102488756(GLYAT) 102500544(GLYATL2)
GVR: 103597522(GLYATL2) 103597524 103608043
CFA: 483463(GLYAT)
CLUD: 112663397(GLYAT)
VVP: 112930488(GLYAT)
VLG: 121471923(GLYAT)
NPO: 129494049(GLYAT)
AML: 100476924
UMR: 103666140
UAH: 113246537(GLYAT)
UAR: 123785071(GLYAT)
ELK: 111149525 111150163
LLV: 125078915
MPUF: 101672896(GLYAT) 101689032(GLYATL2)
MNP: 132015697(GLYATL2) 132020826
MLK: 131811648(GLYATL2) 131812987(GLYAT)
NVS: 122912951 122912953(GLYATL2)
ORO: 101370241(GLYAT) 101370831
EJU: 114215251(GLYATL2) 114215371
ZCA: 113915065 113915068(GLYATL2)
MLX: 118015877(GLYAT) 118016303
NSU: 110575841
LWW: 102749519
FCA: 101094699(GLYATL2) 101097840(GLYAT)
PYU: 121043386(GLYAT) 121043768(GLYATL2)
PCOO: 112865400(GLYAT) 112866035(GLYATL2)
PBG: 122482826(GLYATL2) 122483802
PVIV: 125176690 125176691(GLYATL2)
LRUF: 124504661 124506454
LGF: 123601725 123602724(GLYATL2)
AJU: 106986792
PTG: 102966010(GLYAT) 102966774(GLYATL2)
PPAD: 109246472(GLYAT) 109247014(GLYATL2)
PUC: 125933287 125933299
PLEZ: 122200163(GLYATL2) 122200294(GLYAT)
HHV: 120240296(GLYATL2) 120240385
BTA: 104974345 281787(GLYAT) 515352(GLYATL2) 518623
BOM: 102270060(GLYAT) 102270337 102274551(GLYATL2)
BIU: 109569442(GLYATL2) 109569864 109569929 109569937
BBUB: 102393759 102402141 102407775
BBIS: 104983647(GLYAT) 104987662 104989684 105001532 105001538
CHX: 102175500 102176061 102176349(GLYATL2)
OAS: 101108419 101108685(GLYAT) 101109387(GLYATL2)
BTAX: 128060630 128060651 128060998(GLYATL2)
CSUM: 138092427 138092525 138093231(GLYATL2)
ODA: 120877109 120877110 120877113(GLYATL2)
CCAD: 122449919(GLYATL2) 122449920 122449923
MREE: 136174193 136174414 136174416 136176055(GLYATL2)
OVR: 110137913 110144785(GLYATL2) 110144789(GLYAT)
MBEZ: 129537452 129537453 129554872 129554876 129554878(GLYATL2)
SSC: 100518109 100518644 100525206(GLYATL2)
CFR: 102511836(GLYATL2) 102512308 102523093
CBAI: 105070055 105070057 105070059(GLYATL2)
CDK: 105094918(GLYATL2) 105094920 105094922
VPC: 102531980(GLYATL2) 102532226 102532484
BACU: 103012684(GLYAT) 103013536
BMUS: 118898704 118900085
LVE: 103084960 103085242
OOR: 101286759 101287020
LALB: 132525152 132525775
GMF: 115848535 115848541
DLE: 111183924 111183925
PCAD: 102988596 102988877
PSIU: 116758227 116758717
PPHC: 136126576 136126689
NASI: 112402161 112402409
ECB: 100066603 100068374
EPZ: 103556884 103556886(GLYAT)
EAI: 106825141(GLYAT) 106825142
MYB: 102246796 102250190 102250899(GLYATL2)
MYD: 102767900(GLYAT) 102768179 102769546 102770418(GLYATL2)
MMYO: 118663701 118664988(GLYATL2) 118664990 118664992
MLF: 102438632(GLYATL2) 102441742 102442368 102442997 111822960
MDT: 132241125(GLYATL2) 132241127 132241129 132241131 132241132
MYUM: 139017965 139017966 139017969 139017971 139018969(GLYATL2)
PKL: 118712810(GLYATL2) 118712812 118712813 118712815
EFUS: 103292664 103292666 103292667 103292671(GLYATL2) 103292757
MNA: 107527657(GLYATL2) 107527658(GLYAT)
DRO: 112303553(GLYATL2) 112303558
SHON: 118996870(GLYATL2)
AJM: 119058869
PDIC: 114500943(GLYATL2) 114500944(GLYAT)
PHAS: 123829264 123829308 123829310(GLYATL2)
MMF: 118628366 118628713 118628714(GLYATL2)
PPAM: 129062624(GLYATL2) 129062729
HAI: 109389993(GLYAT) 109390041(GLYATL2)
RFQ: 117029890(GLYATL2) 117030569
PALE: 102891747 102895685
PGIG: 120600763
PVP: 105309550
RAY: 107497335(GLYAT)
TOD: 119254329(GLYATL2) 119254330 119254331 119255256
SARA: 101552140
SFUM: 130045938
SETR: 126017934
LAV: 100662425 100662985 100663214 100668301(GLYAT) 100668589 104847055
TMU: 101350172 101357009
ETF: 101657783 101658105
DNM: 101423027
MDO: 100027269(GLYATL2) 100027301 100027341
GAS: 123251946 123251997 123252718 123256209
SHR: 100916236 100916412 100916499 100916674 100918927
AFZ: 127539822 127540452 127540488 127541632 127541634
PCW: 110200706 110200708
TVP: 118852626 118853002
PBRV: 138177068 138177099
OAA: 100081664 114810122
TACU: 119943602(GLYAT)
NPR: 108798821
RTEM: 120909259 120909260
ACAT: 141106332 141106334 141106335 141106729
BBUF: 121003462 121003478
BGAR: 122940898 122941436 122942117
DTC: 141100079 141100083 141100084
PWL: 138287082 138287083 138287431 138287442 138287443 138288460 138288462 138288769 138300559(GLYATL2)
MUO: 115460522 115482194 115482199 115482242
GSH: 117348575 117348576
LMIX: 132989543
BBEL: 109482204
HAME: 121854082 121862398 121864063
HRJ: 124261194
HASI: 137281948
OSN: 115223248
 » show all
Reference
1  [PMID:457678]
  Authors
Nandi DL, Lucas SV, Webster LT Jr
  Title
Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.
  Journal
J Biol Chem 254:7230-7 (1979)
  Sequence
[bta:281787]
Reference
2  [PMID:13174534]
  Authors
SCHACHTER D, TAGGART JV.
  Title
Glycine N-acylase: purification and properties.
  Journal
J Biol Chem 208:263-75 (1954)
Reference
3  [PMID:931988]
  Authors
Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ.
  Title
Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man.
  Journal
J Biol Chem 251:3352-8 (1976)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.13
IUBMB Enzyme Nomenclature: 2.3.1.13
ExPASy - ENZYME nomenclature database: 2.3.1.13
BRENDA, the Enzyme Database: 2.3.1.13
CAS: 9029-95-2

  All links  
Gene (14)   
   MGENES (13)   
   RefGene (1)   
Protein sequence (47)   
   UniProt (12)   
   SWISS-PROT (11)   
   RefSeq(pep) (24)   
DNA sequence (42)   
   RefSeq(nuc) (25)   
   GenBank (9)   
   EMBL (8)   
Protein domain (6)   
   InterPro (4)   
   Pfam (2)   
All databases (109)   

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