KEGG   ENZYME: 2.3.1.13Help
Entry
EC 2.3.1.13                 Enzyme                                 

Name
glycine N-acyltransferase;
glycine acyltransferase;
glycine-N-acylase
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acyl-CoA:glycine N-acyltransferase
Reaction(IUBMB)
acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
glycine [CPD:C00037]
Product
CoA [CPD:C00010];
N-acylglycine [CPD:C02055]
Comment
The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC 2.3.1.68 glutamine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.
History
EC 2.3.1.13 created 1961
Orthology
K00628  glycine N-acyltransferase / glycine N-benzoyltransferase
K22749  glycine N-acyltransferase
Genes
HSA: 10249(GLYAT) 219970(GLYATL2)
PTR: 451206(GLYATL2) 748398(GLYAT)
PPS: 100979655(GLYATL2) 100980359(GLYAT)
GGO: 101124654(GLYAT) 101125629
PON: 100173810(GLYAT) 100443306
NLE: 100588653 100593268(GLYATL2) 100593830
MCC: 701659(GLYAT)
MCF: 102146442(GLYAT) 102146816
CSAB: 103235080(GLYAT)
RRO: 104680418(GLYAT)
RBB: 108541348(GLYAT)
CJC: 100395000(GLYAT) 100395366(GLYATL2)
SBQ: 101033622(GLYAT) 101033935(GLYATL2)
MMU: 107146(Glyat) 64697(Keg1)
RNO: 171179(Glyatl2) 293779(Glyat)
CCAN: 109678086
OCU: 100345309(GLYAT)
TUP: 102485105 102488756(GLYAT) 102500544(GLYATL2)
CFA: 483463(GLYAT)
AML: 100476924
UMR: 103666140(GLYAT) 103666271(GLYATL2)
ORO: 101370241(GLYAT) 101370831
FCA: 101094699(GLYATL2) 101097840(GLYAT)
PTG: 102966010(GLYAT) 102966774(GLYATL2)
AJU: 106986792(GLYATL2) 106986793
BTA: 104974345 281787(GLYAT) 515352(GLYATL2) 518623
PHD: 102338225(GLYAT) 102338579 102339524(GLYATL2)
BACU: 103012684(GLYAT) 103013536
MYD: 102767900(GLYAT) 102768179 102769546 102770418(GLYATL2)
HAI: 109389993(GLYAT) 109390041(GLYATL2)
RSS: 109438812(GLYAT) 109439517 109439518(GLYATL2)
MDO: 100027219(GLYAT) 100027341
OAA: 100081664(GLYAT)
NPR: 108798821
 » show all
Taxonomy
Reference
1  [PMID:457678]
  Authors
Nandi DL, Lucas SV, Webster LT Jr.
  Title
Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization.
  Journal
J Biol Chem 254:7230-7 (1979)
  Sequence
[bta:281787]
Reference
2  [PMID:13174534]
  Authors
SCHACHTER D, TAGGART JV.
  Title
Glycine N-acylase: purification and properties.
  Journal
J Biol Chem 208:263-75 (1954)
Reference
3  [PMID:931988]
  Authors
Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ.
  Title
Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man.
  Journal
J Biol Chem 251:3352-8 (1976)
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.13
IUBMB Enzyme Nomenclature: 2.3.1.13
ExPASy - ENZYME nomenclature database: 2.3.1.13
BRENDA, the Enzyme Database: 2.3.1.13
CAS: 9029-95-2

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